Synovial regulatory T cells occupy a discrete TCR niche in human arthritis and require local signals to stabilize FOXP3 protein expression

Journal of Immunology

Volumn 195, Issue 12, 2015, Pages 5616-5624

  Bending, David ^a   Giannakopoulou, Eirini ^a,b   Lom, Hannah ^a   Wedderburn, Lucy R ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; GENOMIC DNA; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 6; INTERLEUKIN 7 RECEPTOR; MESSENGER RNA; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR BETA CHAIN; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, HUMAN; LYMPHOCYTE ANTIGEN RECEPTOR;

ANTIGEN EXPRESSION; ARTICLE; BLOOD; CD4+ T LYMPHOCYTE; CELL CULTURE; CELL EXPANSION; CELL LINEAGE; CHRONIC INFLAMMATION; CLONAL VARIATION; CONTROLLED STUDY; DOWN REGULATION; FOXP3 GENE; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; HUMAN TISSUE; IMMUNE RESPONSE; IMMUNOPATHOGENESIS; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; JUVENILE RHEUMATOID ARTHRITIS; MAJOR CLINICAL STUDY; NORMAL HUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STABILITY; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; SYNOVIAL FLUID; SYNOVIUM; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION; TRANSCRIPTION INITIATION; CELL CLONE; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; METABOLISM; TUMOR MICROENVIRONMENT;

ARTHRITIS, JUVENILE; CELLULAR MICROENVIRONMENT; CLONE CELLS; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-6; RECEPTORS, ANTIGEN, T-CELL; SYNOVIAL FLUID; SYNOVIAL MEMBRANE; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, REGULATORY;

EID: 84958280973     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1500391     Document Type: Article

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