Vitamin D decreases adipocyte lipid storage and increases NAD-SIRT1 pathway in 3T3-L1 adipocytes

Nutrition

Volumn 32, Issue 6, 2016, Pages 702-708

  Chang, Eugene ^a   Kim, Yangha ^a  

^a Ewha Womans University   (South Korea)

Author keywords

1,25(OH)2D; Adipocyte; Lipid storage; Lipolysis; NAD; Obesity; SIRT1

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CALCITRIOL; ISOPRENALINE; LIPID; MESSENGER RNA; NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; SIRTUIN 1; VITAMIN D; 1,25-DIHYDROXYVITAMIN D; SIRT1 PROTEIN, MOUSE;

3T3 CELL LINE; ADIPOCYTE; ANIMAL CELL; ARTICLE; BIOACCUMULATION; CELL MATURATION; CELL PROLIFERATION; CELL STIMULATION; CELL VIABILITY; CONTROLLED STUDY; FATTY ACID OXIDATION; GENE; GENE EXPRESSION; LIPID METABOLISM; LIPID STORAGE; LIPOLYSIS; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VITAMIN D RESPONSIVE GENE; ADIPOGENESIS; ANALOGS AND DERIVATIVES; ANIMAL; CELL CULTURE TECHNIQUE; CELL DIFFERENTIATION; DOSE RESPONSE; DRUG EFFECTS; GENETICS; HUMAN; METABOLISM; MOUSE; OXIDATION REDUCTION REACTION; POLYMERASE CHAIN REACTION;

3T3-L1 CELLS; ADIPOCYTES; ADIPOGENESIS; ANIMALS; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION; HUMANS; LIPID METABOLISM; LIPOLYSIS; MICE; NAD; OXIDATION-REDUCTION; POLYMERASE CHAIN REACTION; SIRTUIN 1; VITAMIN D;

EID: 84958259889     PISSN: 08999007     EISSN: 18731244     Source Type: Journal    
DOI: 10.1016/j.nut.2015.12.032     Document Type: Article

References (50)

1. Mokdad A.H., Ford E.S., Bowman B.A., Dietz W.H., Vinicor F., Bales V.S., et al. Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001. JAMA 2003, 289:76-79.
2. Wyatt S.B., Winters K.P., Dubbert P.M. Overweight and obesity: prevalence, consequences, and causes of a growing public health problem. Am J Med Sci 2006, 331:166-174.
3. Tchoukalova Y.D., Sarr M.G., Jensen M.D. Measuring committed preadipocytes in human adipose tissue from severely obese patients by using adipocyte fatty acid binding protein. Am J Physiol Regul Integr Comp Physiol 2004, 287:R1132-R1140.
4. Nishimura S., Manabe I., Nagasaki M., Hosoya Y., Yamashita H., Fujita H., et al. Adipogenesis in obesity requires close interplay between differentiating adipocytes, stromal cells, and blood vessels. Diabetes 2007, 56:1517-1526.
5. Kershaw E.E., Flier J.S. Adipose tissue as an endocrine organ. J Clin Endocrinol Metab 2004, 89:2548-2556.
6. Bell N.H., Epstein S., Greene A., Shary J., Oexmann M.J., Shaw S. Evidence for alteration of the vitamin D-endocrine system in obese subjects. J Clin Invest 1985, 76:370-373.
7. Hypponen E., Power C. Vitamin D status and glucose homeostasis in the 1958 British birth cohort: the role of obesity. Diabetes Care 2006, 29:2244-2246.
8. Arunabh S., Pollack S., Yeh J., Aloia J.F. Body fat content and 25-hydroxyvitamin D levels in healthy women. J Clin Endocrinol Metab 2003, 88:157-161.
9. Snijder M.B., van Dam R.M., Visser M., Deeg D.J., Dekker J.M., Bouter L.M., et al. Adiposity in relation to vitamin D status and parathyroid hormone levels: a population-based study in older men and women. J Clin Endocrinol Metab 2005, 90:4119-4123.
10. Beydoun M.A., Boueiz A., Shroff M.R., Beydoun H.A., Wang Y., Zonderman A.B. Associations among 25-hydroxyvitamin D, diet quality, and metabolic disturbance differ by adiposity in adults in the United States. J Clin Endocrinol Metab 2010, 95:3814-3827.
11. Reinehr T., de Sousa G., Alexy U., Kersting M., Andler W. Vitamin D status and parathyroid hormone in obese children before and after weight loss. Eur J Endocrinol 2007, 157:225-232.
12. Tzotzas T., Papadopoulou F.G., Tziomalos K., Karras S., Gastaris K., Perros P., et al. Rising serum 25-hydroxy-vitamin D levels after weight loss in obese women correlate with improvement in insulin resistance. J Clin Endocrinol Metab 2010, 95:4251-4257.
13. Blumberg J.M., Tzameli I., Astapova I., Lam F.S., Flier J.S., Hollenberg A.N. Complex role of the vitamin D receptor and its ligand in adipogenesis in 3T3-L1 cells. J Biol Chem 2006, 281:11205-11213.
14. Kong J., Li Y.C. Molecular mechanism of 1,25-dihydroxyvitamin D3 inhibition of adipogenesis in 3T3-L1 cells. Am J Physiol Endocrinol Metab 2006, 290:E916-E924.
15. Lee H., Bae S., Yoon Y. Anti-adipogenic effects of 1,25-dihydroxyvitamin D3 are mediated by the maintenance of the wingless-type MMTV integration site/beta-catenin pathway. Int J Mol Med 2012, 30:1219-1224.
16. Vu D., Ong J.M., Clemens T.L., Kern P.A. 1,25-Dihydroxyvitamin D induces lipoprotein lipase expression in 3T3-L1 cells in association with adipocyte differentiation. Endocrinology 1996, 137:1540-1544.
17. Nimitphong H., Holick M.F., Fried S.K., Lee M.J. 25-hydroxyvitamin D(3) and 1,25-dihydroxyvitamin D(3) promote the differentiation of human subcutaneous preadipocytes. PLoS One 2012, 7:e52171.
18. Rodgers J.T., Lerin C., Haas W., Gygi S.P., Spiegelman B.M., Puigserver P. Nutrient control of glucose homeostasis through a complex of PGC-1 alpha and SIRT1. Nature 2005, 434:113-118.
19. Chen D., Bruno J., Easlon E., Lin S.J., Cheng H.L., Alt F.W., et al. Tissue-specific regulation of SIRT1 by calorie restriction. Genes Dev 2008, 22:1753-1757.
20. Hayashida S., Arimoto A., Kuramoto Y., Kozako T., Honda S., Shimeno H., et al. Fasting promotes the expression of SIRT1, an NAD+ -dependent protein deacetylase, via activation of PPARalpha in mice. Mol Cell Biochem 2010, 339:285-292.
21. Gerhart-Hines Z., Rodgers J.T., Bare O., Lerin C., Kim S.H., Mostoslavsky R., et al. Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1 alpha. EMBO J 2007, 26:1913-1923.
22. Canto C., Gerhart-Hines Z., Feige J.N., Lagouge M., Noriega L., Milne J.C., et al. AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity. Nature 2009, 458:1056-1060.
23. Picard F., Kurtev M., Chung N., Topark-Ngarm A., Senawong T., Machado De Oliveira R., et al. SIRT1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma. Nature 2004, 429:771-776.
24. Chalkiadaki A., Guarente L. High-fat diet triggers inflammation-induced cleavage of SIRT1 in adipose tissue to promote metabolic dysfunction. Cell Metab 2012, 16:180-188.
25. Mayoral R., Osborn O., McNelis J., Johnson A.M., Oh da Y., Izquierdo C.L., et al. Adipocyte SIRT1 knockout promotes PPARgamma activity, adipogenesis and insulin sensitivity in chronic-HFD and obesity. Mol Metab 2015, 4:378-391.
26. Poulsen M.M., Vestergaard P.F., Clasen B.F., Radko Y., Christensen L.P., Stodkilde-Jorgensen H., et al. High-dose resveratrol supplementation in obese men: an investigator-initiated, randomized, placebo-controlled clinical trial of substrate metabolism, insulin sensitivity, and body composition. Diabetes 2013, 62:1186-1195.
27. Miyoshi H., Souza S.C., Zhang H.H., Strissel K.J., Christoffolete M.A., Kovsan J., et al. Perilipin promotes hormone-sensitive lipase-mediated adipocyte lipolysis via phosphorylation-dependent and -independent mechanisms. J Biol Chem 2006, 281:15837-15844.
28. Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001, 25:402-408.
29. Sergeev I.N. 1,25-Dihydroxyvitamin D3 induces Ca2+-mediated apoptosis in adipocytes via activation of calpain and caspase-12. Biochem Biophys Res Commun 2009, 384:18-21.
30. Zhuang H., Lin Y., Yang G. Effects of 1,25-dihydroxyvitamin D3 on proliferation and differentiation of porcine preadipocyte in vitro. Chem Biol Interact 2007, 170:114-123.
31. Xu A., Wang Y., Xu J.Y., Stejskal D., Tam S., Zhang J., et al. Adipocyte fatty acid-binding protein is a plasma biomarker closely associated with obesity and metabolic syndrome. Clin Chem 2006, 52:405-413.
32. Ranganathan G., Unal R., Pokrovskaya I., Yao-Borengasser A., Phanavanh B., Lecka-Czernik B., et al. The lipogenic enzymes DGAT1, FAS, and LPL in adipose tissue: effects of obesity, insulin resistance, and TZD treatment. J Lipid Res 2006, 47:2444-2450.
33. Ntambi J.M., Miyazaki M. Regulation of stearoyl-CoA desaturases and role in metabolism. Prog Lipid Res 2004, 43:91-104.
34. McGarry J.D., Brown N.F. The mitochondrial carnitine palmitoyltransferase system. From concept to molecular analysis. Eur J Biochem 1997, 244:1-14.
35. Kersten S., Desvergne B., Wahli W. Roles of PPARs in health and disease. Nature 2000, 405:421-424.
36. Spiegelman B.M. Transcriptional control of mitochondrial energy metabolism through the PGC1 coactivators. Novartis Found Symp 2007, 287:60-63.
37. Puigserver P., Wu Z., Park C.W., Graves R., Wright M., Spiegelman B.M. A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell 1998, 92:829-839.
38. Huang Y., Li X., Wang M., Ning H., Lima A., Li Y., et al. Lipoprotein lipase links vitamin D, insulin resistance, and type 2 diabetes: a cross-sectional epidemiological study. Cardiovasc Diabetol 2013, 12:17.
39. Querfeld U., Hoffmann M.M., Klaus G., Eifinger F., Ackerschott M., Michalk D., et al. Antagonistic effects of vitamin D and parathyroid hormone on lipoprotein lipase in cultured adipocytes. J Am Soc Nephrol 1999, 10:2158-2164.
40. Li J., Byrne M.E., Chang E., Jiang Y., Donkin S.S., Buhman K.K., et al. 1 alpha,25-Dihydroxyvitamin D hydroxylase in adipocytes. J Steroid Biochem Mol Biol 2008, 112:122-126.
41. Maetani M., Maskarinec G., Franke A.A., Cooney R.V. Association of leptin, 25-hydroxyvitamin D, and parathyroid hormone in women. Nutr Cancer 2009, 61:225-231.
42. Menendez C., Lage M., Peino R., Baldelli R., Concheiro P., Diéguez C., et al. Retinoic acid and vitamin D powerfully inhibit in vitro leptin secretion by human adipose tissue. J Endocrinol 2001, 170:425-431.
43. Krishnan J., Danzer C., Simka T., Ukropec J., Walter K.M., Kumpf S., et al. Dietary obesity-associated Hif1 α activation in adipocytes restricts fatty acid oxidation and energy expenditure via suppression of the Sirt2-NAD+ system. Genes Dev 2012, 26:259-270.
44. Canto C., Houtkooper R.H., Pirinen E., Youn D.Y., Oosterveer M.H., Cen Y., et al. The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity. Cell Metab 2012, 15:838-847.
45. Kraus D., Yang Q., Kong D., Banks A.S., Zhang L., Rodgers J.T., et al. Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity. Nature 2014, 508:258-262.
46. Pfluger P.T., Herranz D., Velasco-Miguel S., Serrano M., Tschop M.H. SIRT1 protects against high-fat diet-induced metabolic damage. Proc Natl Acad Sci U S A 2008, 105:9793-9798.
47. Wang L., Teng R., Di L., Rogers H., Wu H., Kopp J.B., et al. PPARalpha and SIRT1 mediate erythropoietin action in increasing metabolic activity and browning of white adipocytes to protect against obesity and metabolic disorders. Diabetes 2013, 62:4122-4131.
48. Gillum M.P., Kotas M.E., Erion D.M., Kursawe R., Chatterjee P., Nead K.T., et al. SIRT1 regulates adipose tissue inflammation. Diabetes 2011, 60:3235-3245.
49. Zehnder D., Bland R., Walker E.A., Bradwell A.R., Howie A.J., Hewison M., et al. Expression of 25-hydroxyvitamin D3-1 alpha-hydroxylase in the human kidney. J Am Soc Nephrol 1999, 10:2465-2473.
50. Dampf Stone A., Batie S.F., Sabir M.S., Jacobs E.T., Lee J.H., Whitfield G.K., et al. Resveratrol potentiates vitamin D and nuclear receptor signaling. J Cell Biochem 2015, 116:1130-1143.