Antioxidant and ACE-inhibitory activities of hemp (Cannabis sativa L.) protein hydrolysates produced by the proteases AFP, HT, Pro-G, actinidin and zingibain

Food Chemistry

Volumn 203, Issue , 2016, Pages 199-206

  Teh, Sue Siang ^a   Bekhit, Alaa El Din A ^a   Carne, Alan ^a   Birch, John ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

ACE inhibitory; Hemp protein isolates; ORAC; Proteases

Indexed keywords

HEMP; HYDROLYSIS; PROTEINS;

ACE-INHIBITORY; ACE-INHIBITORY ACTIVITY; BIOACTIVE PROPERTIES; CASEINOLYTIC ACTIVITY; ORAC; PROTEASES; PROTEIN ISOLATES; SURFACE HYDROPHOBICITY;

ENZYMATIC HYDROLYSIS;

ACTINIDIN; AFP 4000; ANTIOXIDANT; CANNABIS; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HEMP PROTEIN ISOLATE; HT PROTEOLYTIC CONCENTRATE; PROTEIN HYDROLYSATE; PROTEINASE G; UNCLASSIFIED DRUG; VEGETABLE PROTEIN; ZINGIBAIN; 1,1-DIPHENYL-2-PICRYLHYDRAZYL; BIPHENYL DERIVATIVE; CYSTEINE PROTEINASE; DIPEPTIDYL CARBOXYPEPTIDASE; PEPTIDE HYDROLASE; PICRIC ACID;

ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; HYDROPHOBICITY; MOLECULAR WEIGHT; PARTICLE SIZE; PHYSICAL CHEMISTRY; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN HYDROLYSIS; PROTEIN STRUCTURE; PROTEIN UNFOLDING; REACTION TIME; SURFACE PROPERTY; ZETA POTENTIAL; CHEMICAL PHENOMENA; CHEMISTRY; HYDROLYSIS; ISOLATION AND PURIFICATION; POLYACRYLAMIDE GEL ELECTROPHORESIS;

ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANTIOXIDANTS; BIPHENYL COMPOUNDS; CANNABIS; CYSTEINE ENDOPEPTIDASES; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HYDROLYSIS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; PARTICLE SIZE; PEPTIDE HYDROLASES; PEPTIDYL-DIPEPTIDASE A; PICRATES; PROTEIN HYDROLYSATES; SURFACE PROPERTIES;

EID: 84958214206     PISSN: 03088146     EISSN: 18737072     Source Type: Journal    
DOI: 10.1016/j.foodchem.2016.02.057     Document Type: Article

References (27)

1. N. Alizadeh-Pasdar, and E.C. Li-Chan Comparison of protein surface hydrophobicity measured at various pH values using three different fluorescent probes Journal of Agricultural and Food Chemistry 48 2000 328 334
2. T. Amza, I. Amadou, K. Zhu, and H. Zhou Effect of extraction and isolation on physicochemical and functional properties of an underutilized seed protein: Gingerbread plum (Neocarya macrophylla) Food Research International 44 2011 2843 2850
3. J.C. Callaway Hempseed as a nutritional resource: An overview Euphytica 140 2004 65 72
4. B. De Ancos, S. Sgroppo, L. Plaza, and M.P. Cano Possible nutritional and health-related value promotion in orange juice preserved by high-pressure treatment Journal of the Science of Food and Agriculture 82 8 2002 790 796
5. S.J. Fayad, B.G. Zanetti-Ramos, P.L.M. Barreto, V. Soldi, and E. Minatti Morphology of soy protein isolates at oil/water and oil/air interfaces Journal of the Brazilian Chemical Society 24 6 2013 1012 1017
6. A.T. Girgih, A. Alashi, R. He, S. Malomo, and R.E. Aluko Preventive and treatment effects of a hemp seed (Cannabis sativa L.) meal protein hydrolysate against high blood pressure in spontaneously hypertensive rats European Journal of Nutrition 53 2014 1237 1246
7. A.T. Girgih, C.C. Udenigwe, and R.E. Aluko In vitro antioxidant properties of hemp seed (Cannabis sativa L.) protein hydrolysate fractions Journal of the American Oil Chemists Society 88 2011 381 389
8. M. Ha, A.E.D. Bekhit, A. Carne, and D.L. Hopkins Comparison of the proteolytic activities of new commercially available bacterial and fungal proteases toward meat proteins Journal of Food Science 78 2013 C170 C177
9. R. He, A. Alashi, S.A. Malomo, A.T. Girgih, D. Chao, X. Ju, and R.E. Aluko Antihypertensive and free radical scavenging properties of enzymatic rapeseed protein hydrolysates Food Chemistry 141 2013 153 159
10. J.D. House, J. Neufeld, and G. Leson Evaluating the quality of protein from hemp seed (Cannabis sativa L.) products through the use of the protein digestibility-corrected amino acid score method Journal of Agriculture and Food Chemistry 58 2010 11801 11807
11. V.K. Jimsheena, and L.R. Gowda Colorimetric, high-throughput assay for screening angiotensin I-converting enzyme inhibitors Analytical Chemistry 81 2009 9388 9394
12. Y. Li, B. Jiang, T. Zhang, W. Mu, and J. Liu Antioxidant and free radical-scavenging activities of chickpea protein hydrolysate Food Chemistry 106 2008 444 450
13. Y. Liu, G. Zhao, J. Ren, M. Zhao, and B. Yang Effect of denaturation during extraction on the conformational and functional properties of peanut protein isolate Innovative Food Science Emerging Technologies 12 3 2011 375 380
14. S.A. Malomo, and R.E. Aluko A comparative study of the structural and functional properties of isolated hemp seed (Cannabis sativa L.) albumin and globulin fractions Food Hydrocolloids 43 2015 743 752
15. N.L. Opatha Vithana, S.L. Mason, A.E.A. Bekhit, and J.D. Morton In vitro digestion of red deer (Cervus elaphus) and cow (Bos taurus) milk International Food Research Journal 19 4 2012 1367 1374
16. M.C. Orsini Delgado, V.A. Tironi, and M. Cristina Anon Antioxidant activity of amaranth protein or their hydrolysates under simulated gastrointestinal digestion LWT - Food Science and Technology 44 2011 1752 1760
17. S. Patel, R. Cudney, and A. McPherson Crystallographic characterization and molecular symmetry of edestin, a legumin from hemp Journal of Molecular Biology 235 1 1994 361 363
18. E. Rosa Zavareze, A.C. Telles, S.L.M.E. Halal, M. Rocha, R. Colussi, and L.M. Assis C. Prentice-Hernández Production and characterization of encapsulated antioxidative protein hydrolysates from Whitemouth croaker (Micropogonias furnieri) muscle and byproduct LWT - Food Science and Technology 59 2014 841 848
19. K. Ryder, M. Ha, A.E.-D. Bekhit, and A. Carne Characterization of novel fungal and bacterial protease preparations and evaluation of their ability to hydrolyze meat myofibrillar and connective tissue proteins Food Chemistry 172 2014 197 206
20. S. Salgin, U. Salgin, and S. Bahadir Zeta potentials and isoelectric points of biomolecules: The effects of ion types and ionic strengths International Journal of Electromedical Science 7 2012 12404 12414
21. M.R. Segura Campos, L.A. Chel Guerrero, and D.A. Betancur Ancona Angiotensin-I converting enzyme inhibitory and antioxidant activities of peptide fractions extracted by ultrafiltration of cowpea Vigna unguiculata hydrolysates Journal of the Science of Food and Agriculture 90 2010 2512 2518
22. C.-H. Tang, Z. Ten, X.-S. Wang, and X.-Q. Yang Physicochemical and functional properties of hemp (Cannabis sativa L.) protein isolate Journal of Agriculture and Food Chemistry 54 2006 8945 8950
23. C.-H. Tang, X.-S. Wang, and X.-Q. Yang Enzymatic hydrolysis of hemp (Cannabis sativa L.) protein isolate by various proteases and antioxidant properties of the resulting hydrolysates Food Chemistry 114 2009 1484 1490
24. S.-S. Teh, A. Bekhit, A. Carne, and J. Birch Effect of the defatting process, acid and alkali extraction on the physicochemical and functional properties of hemp, flax and canola seed cake protein isolates Journal of Food Measurement and Characterization 8 2014 92 104
25. V.F. Thompson, S. Saldana, J. Cong, and D.E. Goll A BODIPY fluorescent microplate assay for measuring activity of calpains and other proteases Analytical Biochemistry 279 2000 170 178
26. S.-W. Yin, C.-H. Tang, J.-S. Cao, E.-K. Hu, Q.-B. Wen, and X.-Q. Yang Effects of limited enzymatic hydrolysis with trypsin on the functional properties of hemp (Cannabis sativa L.) protein isolate Food Chemistry 106 3 2008 1004 1013
27. L. Zhang, J. Li, and K. Zhou Chelating and radical scavenging activities of soy protein hydrolysates prepared from microbial proteases and their effect on meat lipid peroxidation Bioresource Technology 101 2010 2084 2089