Angiotensin-I converting enzyme inhibitory and antioxidant activities of peptide fractions extracted by ultrafiltration of cowpea Vigna unguiculata hydrolysates

Journal of the Science of Food and Agriculture

Volumn 90, Issue 14, 2010, Pages 2512-2518

  Campos, Maira R Segura ^a   Guerrero, Luis A Chel ^a   Ancona, David A Betancur ^a  

^a UNIVERSIDAD AUTÓNOMA DE YUCATÁN   (Mexico)

Author keywords

ACE inhibitors; Antioxidants; Enzymatic hydrolysis; Peptide fractions; Ultrafiltration; Vigna unguiculata

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; PEPTIDE; PEPTIDE HYDROLASE; PLANT EXTRACT; PROTEIN HYDROLYSATE; VEGETABLE PROTEIN;

ARTICLE; CHEMISTRY; HYDROLYSIS; IC 50; LEGUME; METABOLISM; ULTRAFILTRATION;

ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; FABACEAE; HYDROLYSIS; INHIBITORY CONCENTRATION 50; PEPTIDE HYDROLASES; PEPTIDES; PLANT EXTRACTS; PLANT PROTEINS; PROTEIN HYDROLYSATES; ULTRAFILTRATION;

VIGNA UNGUICULATA;

EID: 78650713791     PISSN: 00225142     EISSN: 10970010     Source Type: Journal    
DOI: 10.1002/jsfa.4114     Document Type: Article

References (40)

1. Seppo L, Jauhiainen T, Poussa T and Korpela R, A fermented milk high in bioactive peptides has a blood pressure-lowering effect in hypertensive subjects. Am J Clin Nutr 77:326-330 (2003).
2. Miguel M, Alonso M, Salaices M, Aleixandre A and López-Fandiño R, Antihypertensive, ACE inhibitory and vasodilator properties of an egg white hydrolysate: effect of a simulated intestinal digestion. Food Chem 104:163-168 (2007).
3. Won-Kyo J, Eresha M, Jae-Young J, Pyo-Jam P, Byeng Wha S, Hyoung Ching K, et al, Angiotensin I-converting enzyme inhibitory peptide from yellowfin sole (Limanda aspera) frame protein and its antihypertensive effect in spontaneously hypertensyve rats. Food Chem 94:26-32 (2006).
4. Saiga A, Tanabe S and Nishimura T, Antioxidant activity of peptides obtained from porcine myofibrillar proteins by protease treatment. J Agric Food Chem 51:3661-3667 (2006).
5. Je JY, Park PJ, Kwon JY and Kim AK, A novel angiotensin I converting enzyme inhibitory peptide from Alaska pollack (Theragra chalcogramma) frame protein hydrolysate. J Agric Food Chem 52:7842-7845 (2004).
6. Jae-Young J, Pyo-Jam P, Eun-Kyung K and Chang-Bum A, Antioxidant and angiotensin I converting enzyme inhibitory activity of Bambusae caulis in Liquamen. Food Chem 113:932-935 (2009).
7. Giasson BI, Ischiropoulos H, Lee VMY and Trojanowski JQ, Therelationship between oxidative/nitrosative stress and pathological inclusions in Alzheimer's and Parkinson's diseases. Free Radical Biol Med 32:1264-1275 (2002).
8. Pellegrini N, Del Rio D, Colombi B, Bianchi M and Brighenti F, Application of the 2,2′-azinobis (3.ethylbenzothiazoline-6-sulfonic acid) radical cation assay to a flow injection system for the evaluation of antioxidant activity of some pure compounds and beverages. J Agric Food Chem 51:260-264 (2003).
9. Liu JR, Chen MJ and Lin CW, Antimutagenic and antioxidant properties of milk-kefir and soymilk-kefir. J Agric Food Chem 53:2467-2474 (2005).
10. Hong LG, Wei L, Liu H and Hui SY, Mung-bean protein hydrolysates obtained with alcalase exhibit angiotensin I-converting enzyme inhibitory activity. Food Sci Technol Int 11:281-287 (2005).
11. Hernández-Ledesma B, Amigo L, Ramos M and Recio I, Angiotensin converting enzyme inhibitory activity in commercial fermented products: formation of peptides under simulated gastrointestinal digestion. J Agric Food Chem 52:1504-1510 (2004).
12. Freitas RL, Teixeira AR and Ferreira RB, Characterization of the proteins from Vigna unguiculata seeds. J Agric Food Chem 52:1682-1687 (2004).
13. Araujo-González F, Chel-Guerrero L and Betancur-Ancona D, Functional properties of hydrolysates from cowpea (V. unguiculata) seeds. In Advances in Food Science and Food Biotechnology in Developing Countries, Vol. 24, 173-183 (2008).
14. Torruco-Uco J, Chel-Guerrero L, Martínez-Ayala A, Dávila-Ortíz G and Betancur-Ancona D, Angiotensin I converting enzyme inhibitory and antioxidant activities of protein hydrolysates from Phaseolus lunatus and Phaseolus vulgaris seeds. Food Sci Technol 42:1597-1604 (2009).
15. Betancur-Ancona D, Gallegos-Tintoré S and Chel-Guerrero L, Wet fractionation of Phaseolus lunatus seeds: partial characterization of starch and protein. J Sci Food Agric 84:1193-1201 (2004).
16. Pedroche J, Yust MM, Girón-Calle J, Alaiz M, Millán F and Vioque J, Utilization of chickpea protein isolates for the production of peptides with angiotensin I converting enzyme inhibitory activity. J Sci Food Agric 82:960-965 (2002).
17. Megías C, Yust MM, Pedroche J, Lquari H, Girón-Calle J, Alaiz M, et al, Purification of an ACE inhibitory peptide after hydrolysis of sunflower (Helianthus annuus L.) protein isolates. J Agric Food Chem 52:1928-1932 (2004).
18. Yang Y, Marczak DE, Yokoo M, Usui H and Yoshikawa M, Isolation and antihypertensive effect of angiotensin I-converting enzyme (ACE) inhibitory peptides from spinach rubisco. J Agric Food Chem 51:4897-4902 (2003).
19. Nielsen P, Petersen D and Dammann C, Improved method for determining food protein degree of hydrolysis. J Food Sci 66:642-646 (2001).
20. Cho MJ, Unklesbay N, Hsieh F and Clarke AD, Hydrophobicity of bitter peptides from soy protein hydrolysate. J Agric Food Chem 52:5895-5901 (2004).
21. Hayakari M, Kondo Y and Izumi H, A rapid and simple spectrophotometric assay of angiotensin-converting enzyme. Anal Biochem 84:361-369 (1978).
22. Pukalskas A, Van Beek T, Venskutonis R, Linssen J, Van Veldhuizen A and Groot A, Identification of radical scavengers in sweet grass (Hierochloe odorata). J Agric Food Chem 50:2914-2919 (2002).
23. Montgomery D, Diseño y análisis de experimentos. Limusa-Wiley, Mexico (2004).
24. Vioque J, Sánchez-Vioque R, Clemente A, Pedroche J, Bautista J and Millan F, Production and characterization of an extensive rapeseed protein hydrolysate. J Am Òil Chem Soc 76:819-823 (1999).
25. Doucet D, Otter DE, Gauthier SF and Foegeding EA, Enzyme-induced gelation of extensively hydrolyzed whey proteins by Alcalase: peptide identification and determination of enzyme specificity. J Agric Food Chem 51:6300-6308 (2003).
26. Pedroche J, Yust M, Girón-Calle J, Vioque J, Alaiz M and Millán F, Plant protein hydrolysates and tailor-made foods. Electron J Environ Agric Food Chem 2:233-235 (2003).
27. Clemente A, Vioque J, Sánchez-Vioque R, Pedroche J and Millán F, Production of extensive chickpea (Cicer arietinum L.) protein hydrolysates with reduced antigenic activity. J Agric Food Chem 47:3776-3781 (1999).
28. Pommer K, New proteolytic enzymes for the production of savory ingredients. Cereal Foods World 40:745-748 (1995).
29. Qi M, Hettiarachychy N and Kalapathy U, Solubility and emulsifying properties of soy protein isolates modified by pancreatin. J Food Sci 62:1110-1115 (1997).
30. Korhonen H and Pihlanto A, Food-derived bioactive peptides: opportunities for designing future foods. Curr Pharm Des 9:1297-1308 (2003).
31. Yang Y, Marczak ED, Yokoo M, Usui H and Yoshikawa M, Isolation and antihipertensive effect of angiotensin I converting enzyme (ACE) inhibittory peptides from spinach rubisco. J Agric Food Chem 51:4897-4902 (2003).
32. Cheung HS, Wang FL, Ondetti MA, Sabo EF and Cushman DW, Binding of peptide substrates and inhibitors of angiotensin-converting enzyme. J Biol Chem 255: 401-407 (1980).
33. Xue-Ying M, Jin-Ren N, Wei-Ling S, Peng-Peng H and Li F, Value-added utilization of yak milk casein for the production of angiotensin-I-converting enzyme inhibitory peptides. Food Chem 103:1282-1287 (2007).
34. Dávalos A, Miguel M, Bartolomé Band López-Fandiño R, Antioxidant activity of peptides derived from egg white proteins by enzymatic hydrolysis. J Food Prot 67:1939-1944 (2004).
35. Elias RJ, Kellerby SS and Decker EA, Antioxidant activity of proteins and peptides. Crit Rev Food Sci Nutr 48:430-411 (2008).
36. Xiang-Yu C, Jin-Hwa K, Xin Z, Bao-Qiong C, Bum-Chun L, Hyeong-Bae P, et al, Antioxidative and acute anti-inflammatory effects of Campsis grandiflora flower. J Ethnopharmacol 103:223-228 (2006).
37. Hui A, Furong W and Chaoliang L, Antioxidant activities of proteinenriched fraction from the larvae of housefly, Musca domestica. Nat Prod Res 22:507-515 (2008).
38. Larson M, Donovan SM and Potter SM, Effects of dietary protein source on cholesterol metabolism in neonatal pigs. Nutr Res 16:1563-1574 (1996).
39. Pihlanto-Leppälä A, Rokka T and Korhonen H, Angiotensin converting enzyme inhibitory peptides derived from bovine milk proteins. Int Dairy J 8:325-331 (1998).
40. Pihlanto A, Koskinen P, Piilola K, Tupasela T and Korhonen H, Angiotensin I converting enzyme inhibitory properties of whey protein digests: concentration and characterization of active peptides. J Dairy Res 67: 53-64 (2000).