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Volumn 7, Issue JAN, 2016, Pages

Natural killer cells and liver fibrosis

Author keywords

Fibrosis; Liver disease; Natural killer cells; Stellate cells

Indexed keywords

CARBON TETRACHLORIDE; CD18 ANTIGEN; CD2 ANTIGEN; CD56 ANTIGEN; CD57 ANTIGEN; CD69 ANTIGEN; CHEMOKINE RECEPTOR CXCR6; GAMMA INTERFERON; INTERCELLULAR ADHESION MOLECULE 1; LYMPHOCYTE ANTIGEN; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; PARACETAMOL; PLATELET DERIVED GROWTH FACTOR; RANTES; SIGLEC 9; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; VASCULAR ADHESION PROTEIN 1;

EID: 84958153545     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2016.00019     Document Type: Short Survey
Times cited : (96)

References (83)
  • 2
    • 84906772735 scopus 로고    scopus 로고
    • How to trigger a killer: modulation of natural killer cell reactivity on many levels
    • Watzl C. How to trigger a killer: modulation of natural killer cell reactivity on many levels. Adv Immunol (2014) 124:137-70. doi:10.1016/B978-0-12-800147-9.00005-4
    • (2014) Adv Immunol , vol.124 , pp. 137-170
    • Watzl, C.1
  • 3
    • 84908232227 scopus 로고    scopus 로고
    • Natural killer cell regulation-beyond the receptors
    • Watzl C, Urlaub D, Fasbender F, Claus M. Natural killer cell regulation-beyond the receptors. F1000Prime Rep (2014) 6:87. doi:10.12703/P6-87
    • (2014) F1000Prime Rep , vol.6 , pp. 87
    • Watzl, C.1    Urlaub, D.2    Fasbender, F.3    Claus, M.4
  • 5
    • 0035165909 scopus 로고    scopus 로고
    • Immunology of the healthy liver: old questions and new insights
    • Mehal WZ, Azzaroli F, Crispe IN. Immunology of the healthy liver: old questions and new insights. Gastroenterology (2001) 120:250-60. doi:10.1053/gast.2001.20947
    • (2001) Gastroenterology , vol.120 , pp. 250-260
    • Mehal, W.Z.1    Azzaroli, F.2    Crispe, I.N.3
  • 6
    • 0017146459 scopus 로고
    • The pit cell: description of a new type of cell occurring in rat liver sinusoids and peripheral blood
    • Wisse E, Van't Noordende JM, Van Der Meulen J, Daems WT. The pit cell: description of a new type of cell occurring in rat liver sinusoids and peripheral blood. Cell Tissue Res (1976) 173:423-35. doi:10.1007/BF00224305
    • (1976) Cell Tissue Res , vol.173 , pp. 423-435
    • Wisse, E.1    Van't Noordende, J.M.2    Van Der Meulen, J.3    Daems, W.T.4
  • 7
    • 67650750880 scopus 로고    scopus 로고
    • The liver as a lymphoid organ
    • Crispe IN. The liver as a lymphoid organ. Annu Rev Immunol (2009) 27:147-63. doi:10.1146/annurev.immunol.021908.132629
    • (2009) Annu Rev Immunol , vol.27 , pp. 147-163
    • Crispe, I.N.1
  • 8
    • 84886294585 scopus 로고    scopus 로고
    • The role of natural killer cells in autoimmune liver disease: a comprehensive review
    • Hudspeth K, Pontarini E, Tentorio P, Cimino M, Donadon M, Torzilli G, et al. The role of natural killer cells in autoimmune liver disease: a comprehensive review. J Autoimmun (2013) 46:55-65. doi:10.1016/j.jaut.2013.07.003
    • (2013) J Autoimmun , vol.46 , pp. 55-65
    • Hudspeth, K.1    Pontarini, E.2    Tentorio, P.3    Cimino, M.4    Donadon, M.5    Torzilli, G.6
  • 9
    • 84862692575 scopus 로고    scopus 로고
    • Migration of lymphocytes into hepatic sinusoids
    • Crispe IN. Migration of lymphocytes into hepatic sinusoids. J Hepatol (2012) 57:218-20. doi:10.1016/j.jhep.2011.12.035
    • (2012) J Hepatol , vol.57 , pp. 218-220
    • Crispe, I.N.1
  • 10
    • 0029860153 scopus 로고    scopus 로고
    • The role of adhesion molecules in the recruitment of hepatic natural killer cells (pit cells) in rat liver
    • Luo D, Vanderkerken K, Bouwens L, Kuppen PJ, Baekeland M, Seynaeve C, et al. The role of adhesion molecules in the recruitment of hepatic natural killer cells (pit cells) in rat liver. Hepatology (1996) 24:1475-80. doi:10.1002/hep.510240629
    • (1996) Hepatology , vol.24 , pp. 1475-1480
    • Luo, D.1    Vanderkerken, K.2    Bouwens, L.3    Kuppen, P.J.4    Baekeland, M.5    Seynaeve, C.6
  • 11
    • 0037100288 scopus 로고    scopus 로고
    • Vascular adhesion protein-1 mediates adhesion and transmigration of lymphocytes on human hepatic endothelial cells
    • Lalor PF, Edwards S, McNab G, Salmi M, Jalkanen S, Adams DH. Vascular adhesion protein-1 mediates adhesion and transmigration of lymphocytes on human hepatic endothelial cells. J Immunol (2002) 169:983-92. doi:10.4049/jimmunol.169.2.983
    • (2002) J Immunol , vol.169 , pp. 983-992
    • Lalor, P.F.1    Edwards, S.2    McNab, G.3    Salmi, M.4    Jalkanen, S.5    Adams, D.H.6
  • 12
    • 80053364442 scopus 로고    scopus 로고
    • Siglec-9 is a novel leukocyte ligand for vascular adhesion protein-1 and can be used in PET imaging of inflammation and cancer
    • Aalto K, Autio A, Kiss EA, Elima K, Nymalm Y, Veres TZ, et al. Siglec-9 is a novel leukocyte ligand for vascular adhesion protein-1 and can be used in PET imaging of inflammation and cancer. Blood (2011) 118:3725-33. doi:10.1182/blood-2010-09-311076
    • (2011) Blood , vol.118 , pp. 3725-3733
    • Aalto, K.1    Autio, A.2    Kiss, E.A.3    Elima, K.4    Nymalm, Y.5    Veres, T.Z.6
  • 13
    • 84928825044 scopus 로고    scopus 로고
    • Re-examining the origin and function of liver-resident NK cells
    • Peng H, Tian Z. Re-examining the origin and function of liver-resident NK cells. Trends Immunol (2015) 36:293-9. doi:10.1016/j.it.2015.03.006
    • (2015) Trends Immunol , vol.36 , pp. 293-299
    • Peng, H.1    Tian, Z.2
  • 14
    • 33644517272 scopus 로고    scopus 로고
    • Difference in cytotoxicity against hepatocellular carcinoma between liver and periphery natural killer cells in humans
    • Ishiyama K, Ohdan H, Ohira M, Mitsuta H, Arihiro K, Asahara T. Difference in cytotoxicity against hepatocellular carcinoma between liver and periphery natural killer cells in humans. Hepatology (2006) 43:362-72. doi:10.1002/hep.21035
    • (2006) Hepatology , vol.43 , pp. 362-372
    • Ishiyama, K.1    Ohdan, H.2    Ohira, M.3    Mitsuta, H.4    Arihiro, K.5    Asahara, T.6
  • 15
    • 44849125747 scopus 로고    scopus 로고
    • CD27 defines phenotypically and functionally different human NK cell subsets
    • Vossen MT, Matmati M, Hertoghs KM, Baars PA, Gent MR, Leclercq G, et al. CD27 defines phenotypically and functionally different human NK cell subsets. J Immunol (2008) 180:3739-45. doi:10.4049/jimmunol.180.6.3739
    • (2008) J Immunol , vol.180 , pp. 3739-3745
    • Vossen, M.T.1    Matmati, M.2    Hertoghs, K.M.3    Baars, P.A.4    Gent, M.R.5    Leclercq, G.6
  • 16
    • 77954169111 scopus 로고    scopus 로고
    • Liver grafts contain a unique subset of natural killer cells that are transferred into the recipient after liver transplantation
    • Moroso V, Metselaar HJ, Mancham S, Tilanus HW, Eissens D, Van Der Meer A, et al. Liver grafts contain a unique subset of natural killer cells that are transferred into the recipient after liver transplantation. Liver Transpl (2010) 16:895-908. doi:10.1002/lt.22080
    • (2010) Liver Transpl , vol.16 , pp. 895-908
    • Moroso, V.1    Metselaar, H.J.2    Mancham, S.3    Tilanus, H.W.4    Eissens, D.5    Van Der Meer, A.6
  • 17
    • 84880838425 scopus 로고    scopus 로고
    • NK cell isolation from liver biopsies: phenotypic and functional analysis of low cell numbers by flow cytometry
    • Li N, Puga Yung GL, Pradier A, Toso C, Giostra E, Morard I, et al. NK cell isolation from liver biopsies: phenotypic and functional analysis of low cell numbers by flow cytometry. Front Immunol (2013) 4:61. doi:10.3389/fimmu.2013.00061
    • (2013) Front Immunol , vol.4 , pp. 61
    • Li, N.1    Puga Yung, G.L.2    Pradier, A.3    Toso, C.4    Giostra, E.5    Morard, I.6
  • 18
    • 84977871295 scopus 로고    scopus 로고
    • Natural killer cell maturation markers in the human liver and expansion of an NKG2C+KIR+ population
    • Hydes T, Abuhilal M, Armstrong T, Primrose J, Takhar A, Khakoo S. Natural killer cell maturation markers in the human liver and expansion of an NKG2C+KIR+ population. Lancet (2015) 385(Suppl 1):S45. doi:10.1016/S0140-6736(15)60360-9
    • (2015) Lancet , vol.385
    • Hydes, T.1    Abuhilal, M.2    Armstrong, T.3    Primrose, J.4    Takhar, A.5    Khakoo, S.6
  • 20
    • 84953345460 scopus 로고    scopus 로고
    • Human liver-resident CD56/CD16 NK cells are retained within hepatic sinusoids via the engagement of CCR5 and CXCR6 pathways
    • Hudspeth K, Donadon M, Cimino M, Pontarini E, Tentorio P, Preti M, et al. Human liver-resident CD56/CD16 NK cells are retained within hepatic sinusoids via the engagement of CCR5 and CXCR6 pathways. J Autoimmun (2016) 66:40-50. doi:10.1016/j.jaut.2015.08.011
    • (2016) J Autoimmun , vol.66 , pp. 40-50
    • Hudspeth, K.1    Donadon, M.2    Cimino, M.3    Pontarini, E.4    Tentorio, P.5    Preti, M.6
  • 21
    • 11844294973 scopus 로고    scopus 로고
    • CXC chemokine ligand 16 promotes integrin-mediated adhesion of liver-infiltrating lymphocytes to cholangiocytes and hepatocytes within the inflamed human liver
    • Heydtmann M, Lalor PF, Eksteen JA, Hubscher SG, Briskin M, Adams DH. CXC chemokine ligand 16 promotes integrin-mediated adhesion of liver-infiltrating lymphocytes to cholangiocytes and hepatocytes within the inflamed human liver. J Immunol (2005) 174:1055-62. doi:10.4049/jimmunol.174.2.1055
    • (2005) J Immunol , vol.174 , pp. 1055-1062
    • Heydtmann, M.1    Lalor, P.F.2    Eksteen, J.A.3    Hubscher, S.G.4    Briskin, M.5    Adams, D.H.6
  • 22
    • 0036079077 scopus 로고    scopus 로고
    • In vivo developmental stages in murine natural killer cell maturation
    • Kim S, Iizuka K, Kang HS, Dokun A, French AR, Greco S, et al. In vivo developmental stages in murine natural killer cell maturation. Nat Immunol (2002) 3:523-8. doi:10.1038/ni796
    • (2002) Nat Immunol , vol.3 , pp. 523-528
    • Kim, S.1    Iizuka, K.2    Kang, H.S.3    Dokun, A.4    French, A.R.5    Greco, S.6
  • 23
    • 2342447293 scopus 로고    scopus 로고
    • Liver NK cells expressing TRAIL are toxic against self hepatocytes in mice
    • Ochi M, Ohdan H, Mitsuta H, Onoe T, Tokita D, Hara H, et al. Liver NK cells expressing TRAIL are toxic against self hepatocytes in mice. Hepatology (2004) 39:1321-31. doi:10.1002/hep.20204
    • (2004) Hepatology , vol.39 , pp. 1321-1331
    • Ochi, M.1    Ohdan, H.2    Mitsuta, H.3    Onoe, T.4    Tokita, D.5    Hara, H.6
  • 24
    • 20144370572 scopus 로고    scopus 로고
    • TRAIL identifies immature natural killer cells in newborn mice and adult mouse liver
    • Takeda K, Cretney E, Hayakawa Y, Ota T, Akiba H, Ogasawara K, et al. TRAIL identifies immature natural killer cells in newborn mice and adult mouse liver. Blood (2005) 105:2082-9. doi:10.1182/blood-2004-08-3262
    • (2005) Blood , vol.105 , pp. 2082-2089
    • Takeda, K.1    Cretney, E.2    Hayakawa, Y.3    Ota, T.4    Akiba, H.5    Ogasawara, K.6
  • 27
    • 84898640432 scopus 로고    scopus 로고
    • Differentiation of type 1 ILCs from a common progenitor to all helper-like innate lymphoid cell lineages
    • Klose CS, Flach M, Mohle L, Rogell L, Hoyler T, Ebert K, et al. Differentiation of type 1 ILCs from a common progenitor to all helper-like innate lymphoid cell lineages. Cell (2014) 157:340-56. doi:10.1016/j.cell.2014.03.030
    • (2014) Cell , vol.157 , pp. 340-356
    • Klose, C.S.1    Flach, M.2    Mohle, L.3    Rogell, L.4    Hoyler, T.5    Ebert, K.6
  • 28
    • 84862777436 scopus 로고    scopus 로고
    • The transcription factors T-bet and Eomes control key checkpoints of natural killer cell maturation
    • Gordon SM, Chaix J, Rupp LJ, Wu J, Madera S, Sun JC, et al. The transcription factors T-bet and Eomes control key checkpoints of natural killer cell maturation. Immunity (2012) 36:55-67. doi:10.1016/j.immuni.2011.11.016
    • (2012) Immunity , vol.36 , pp. 55-67
    • Gordon, S.M.1    Chaix, J.2    Rupp, L.J.3    Wu, J.4    Madera, S.5    Sun, J.C.6
  • 29
    • 84896847858 scopus 로고    scopus 로고
    • T-bet and Eomes instruct the development of two distinct natural killer cell lineages in the liver and in the bone marrow
    • Daussy C, Faure F, Mayol K, Viel S, Gasteiger G, Charrier E, et al. T-bet and Eomes instruct the development of two distinct natural killer cell lineages in the liver and in the bone marrow. J Exp Med (2014) 211:563-77. doi:10.1084/jem.20131560
    • (2014) J Exp Med , vol.211 , pp. 563-577
    • Daussy, C.1    Faure, F.2    Mayol, K.3    Viel, S.4    Gasteiger, G.5    Charrier, E.6
  • 30
    • 84897965554 scopus 로고    scopus 로고
    • Tissue-resident natural killer cells and their potential diversity
    • Sojka DK, Tian Z, Yokoyama WM. Tissue-resident natural killer cells and their potential diversity. Semin Immunol (2014) 26:127-31. doi:10.1016/j.smim.2014.01.010
    • (2014) Semin Immunol , vol.26 , pp. 127-131
    • Sojka, D.K.1    Tian, Z.2    Yokoyama, W.M.3
  • 31
    • 78449275107 scopus 로고    scopus 로고
    • Critical role for the chemokine receptor CXCR6 in NK cell-mediated antigen-specific memory of haptens and viruses
    • Paust S, Gill HS, Wang BZ, Flynn MP, Moseman EA, Senman B, et al. Critical role for the chemokine receptor CXCR6 in NK cell-mediated antigen-specific memory of haptens and viruses. Nat Immunol (2010) 11:1127-35. doi:10.1038/ni.1953
    • (2010) Nat Immunol , vol.11 , pp. 1127-1135
    • Paust, S.1    Gill, H.S.2    Wang, B.Z.3    Flynn, M.P.4    Moseman, E.A.5    Senman, B.6
  • 32
    • 84875862176 scopus 로고    scopus 로고
    • Liver-resident NK cells confer adaptive immunity in skin-contact inflammation
    • Peng H, Jiang X, Chen Y, Sojka DK, Wei H, Gao X, et al. Liver-resident NK cells confer adaptive immunity in skin-contact inflammation. J Clin Invest (2013) 123:1444-56. doi:10.1172/JCI66381
    • (2013) J Clin Invest , vol.123 , pp. 1444-1456
    • Peng, H.1    Jiang, X.2    Chen, Y.3    Sojka, D.K.4    Wei, H.5    Gao, X.6
  • 33
    • 84924529960 scopus 로고    scopus 로고
    • Cutting edge: identification and characterization of human intrahepatic CD49a+ NK cells
    • Marquardt N, Beziat V, Nystrom S, Hengst J, Ivarsson MA, Kekalainen E, et al. Cutting edge: identification and characterization of human intrahepatic CD49a+ NK cells. J Immunol (2015) 194:2467-71. doi:10.4049/jimmunol.1402756
    • (2015) J Immunol , vol.194 , pp. 2467-2471
    • Marquardt, N.1    Beziat, V.2    Nystrom, S.3    Hengst, J.4    Ivarsson, M.A.5    Kekalainen, E.6
  • 34
  • 35
    • 84883464564 scopus 로고    scopus 로고
    • Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME
    • Godoy P, Hewitt NJ, Albrecht U, Andersen ME, Ansari N, Bhattacharya S, et al. Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME. Arch Toxicol (2013) 87:1315-530. doi:10.1007/s00204-013-1078-5
    • (2013) Arch Toxicol , vol.87 , pp. 1315-1530
    • Godoy, P.1    Hewitt, N.J.2    Albrecht, U.3    Andersen, M.E.4    Ansari, N.5    Bhattacharya, S.6
  • 36
  • 37
    • 77953771023 scopus 로고    scopus 로고
    • Prediction and validation of cell alignment along microvessels as order principle to restore tissue architecture in liver regeneration
    • Hoehme S, Brulport M, Bauer A, Bedawy E, Schormann W, Hermes M, et al. Prediction and validation of cell alignment along microvessels as order principle to restore tissue architecture in liver regeneration. Proc Natl Acad Sci U S A (2010) 107:10371-6. doi:10.1073/pnas.0909374107
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 10371-10376
    • Hoehme, S.1    Brulport, M.2    Bauer, A.3    Bedawy, E.4    Schormann, W.5    Hermes, M.6
  • 38
    • 84926409090 scopus 로고    scopus 로고
    • How predictive quantitative modelling of tissue organisation can inform liver disease pathogenesis
    • Drasdo D, Hoehme S, Hengstler JG. How predictive quantitative modelling of tissue organisation can inform liver disease pathogenesis. J Hepatol (2014) 61:951-6. doi:10.1016/j.jhep.2014.06.013
    • (2014) J Hepatol , vol.61 , pp. 951-956
    • Drasdo, D.1    Hoehme, S.2    Hengstler, J.G.3
  • 39
    • 84901262468 scopus 로고    scopus 로고
    • Integrated metabolic spatial-temporal model for the prediction of ammonia detoxification during liver damage and regeneration
    • Schliess F, Hoehme S, Henkel SG, Ghallab A, Driesch D, Bottger J, et al. Integrated metabolic spatial-temporal model for the prediction of ammonia detoxification during liver damage and regeneration. Hepatology (2014) 60:2040-51. doi:10.1002/hep.27136
    • (2014) Hepatology , vol.60 , pp. 2040-2051
    • Schliess, F.1    Hoehme, S.2    Henkel, S.G.3    Ghallab, A.4    Driesch, D.5    Bottger, J.6
  • 40
  • 42
    • 84884735611 scopus 로고    scopus 로고
    • Experimental liver fibrosis research: update on animal models, legal issues and translational aspects
    • Liedtke C, Luedde T, Sauerbruch T, Scholten D, Streetz K, Tacke F, et al. Experimental liver fibrosis research: update on animal models, legal issues and translational aspects. Fibrogenesis Tissue Repair (2013) 6:19. doi:10.1186/1755-1536-6-19
    • (2013) Fibrogenesis Tissue Repair , vol.6 , pp. 19
    • Liedtke, C.1    Luedde, T.2    Sauerbruch, T.3    Scholten, D.4    Streetz, K.5    Tacke, F.6
  • 43
    • 84896806249 scopus 로고    scopus 로고
    • Liver fibrosis and repair: immune regulation of wound healing in a solid organ
    • Pellicoro A, Ramachandran P, Iredale JP, Fallowfield JA. Liver fibrosis and repair: immune regulation of wound healing in a solid organ. Nat Rev Immunol (2014) 14:181-94. doi:10.1038/nri3623
    • (2014) Nat Rev Immunol , vol.14 , pp. 181-194
    • Pellicoro, A.1    Ramachandran, P.2    Iredale, J.P.3    Fallowfield, J.A.4
  • 44
    • 33744538682 scopus 로고    scopus 로고
    • Modern pathogenetic concepts of liver fibrosis suggest stellate cells and TGF-beta as major players and therapeutic targets
    • Gressner AM, Weiskirchen R. Modern pathogenetic concepts of liver fibrosis suggest stellate cells and TGF-beta as major players and therapeutic targets. J Cell Mol Med (2006) 10:76-99. doi:10.1111/j.1582-4934.2006.tb00292.x
    • (2006) J Cell Mol Med , vol.10 , pp. 76-99
    • Gressner, A.M.1    Weiskirchen, R.2
  • 45
    • 84893141250 scopus 로고    scopus 로고
    • Hepatic stellate cells and liver fibrosis
    • Puche JE, Saiman Y, Friedman SL. Hepatic stellate cells and liver fibrosis. Compr Physiol (2013) 3:1473-92. doi:10.1002/cphy.c120035
    • (2013) Compr Physiol , vol.3 , pp. 1473-1492
    • Puche, J.E.1    Saiman, Y.2    Friedman, S.L.3
  • 46
    • 84893724364 scopus 로고    scopus 로고
    • Balance of inflammatory pathways and interplay of immune cells in the liver during homeostasis and injury
    • Baeck C, Tacke F. Balance of inflammatory pathways and interplay of immune cells in the liver during homeostasis and injury. EXCLI J (2014) 13:67-81.
    • (2014) EXCLI J , vol.13 , pp. 67-81
    • Baeck, C.1    Tacke, F.2
  • 47
    • 0034808310 scopus 로고    scopus 로고
    • History, heterogeneity, developmental biology, and functions of quiescent hepatic stellate cells
    • Geerts A. History, heterogeneity, developmental biology, and functions of quiescent hepatic stellate cells. Semin Liver Dis (2001) 21:311-35. doi:10.1055/s-2001-17550
    • (2001) Semin Liver Dis , vol.21 , pp. 311-335
    • Geerts, A.1
  • 48
    • 84901263446 scopus 로고    scopus 로고
    • Protocols for staining of bile canalicular and sinusoidal networks of human, mouse and pig livers, three-dimensional reconstruction and quantification of tissue microarchitecture by image processing and analysis
    • Hammad S, Hoehme S, Friebel A, Von Recklinghausen I, Othman A, Begher-Tibbe B, et al. Protocols for staining of bile canalicular and sinusoidal networks of human, mouse and pig livers, three-dimensional reconstruction and quantification of tissue microarchitecture by image processing and analysis. Arch Toxicol (2014) 88:1161-83. doi:10.1007/s00204-014-1243-5
    • (2014) Arch Toxicol , vol.88 , pp. 1161-1183
    • Hammad, S.1    Hoehme, S.2    Friebel, A.3    Von Recklinghausen, I.4    Othman, A.5    Begher-Tibbe, B.6
  • 49
    • 81155123815 scopus 로고    scopus 로고
    • Modification of chemokine pathways and immune cell infiltration as a novel therapeutic approach in liver inflammation and fibrosis
    • Zimmermann HW, Tacke F. Modification of chemokine pathways and immune cell infiltration as a novel therapeutic approach in liver inflammation and fibrosis. Inflamm Allergy Drug Targets (2011) 10:509-36. doi:10.2174/187152811798104890
    • (2011) Inflamm Allergy Drug Targets , vol.10 , pp. 509-536
    • Zimmermann, H.W.1    Tacke, F.2
  • 50
    • 33744939234 scopus 로고    scopus 로고
    • Anti-fibrotic activity of NK cells in experimental liver injury through killing of activated HSC
    • Melhem A, Muhanna N, Bishara A, Alvarez CE, Ilan Y, Bishara T, et al. Anti-fibrotic activity of NK cells in experimental liver injury through killing of activated HSC. J Hepatol (2006) 45:60-71. doi:10.1016/j.jhep.2005.12.025
    • (2006) J Hepatol , vol.45 , pp. 60-71
    • Melhem, A.1    Muhanna, N.2    Bishara, A.3    Alvarez, C.E.4    Ilan, Y.5    Bishara, T.6
  • 51
    • 32044443617 scopus 로고    scopus 로고
    • Natural killer cells ameliorate liver fibrosis by killing activated stellate cells in NKG2D-dependent and tumor necrosis factor-related apoptosis-inducing ligand-dependent manners
    • Radaeva S, Sun R, Jaruga B, Nguyen VT, Tian Z, Gao B. Natural killer cells ameliorate liver fibrosis by killing activated stellate cells in NKG2D-dependent and tumor necrosis factor-related apoptosis-inducing ligand-dependent manners. Gastroenterology (2006) 130:435-52. doi:10.1053/j.gastro.2005.10.055
    • (2006) Gastroenterology , vol.130 , pp. 435-452
    • Radaeva, S.1    Sun, R.2    Jaruga, B.3    Nguyen, V.T.4    Tian, Z.5    Gao, B.6
  • 52
    • 35349017872 scopus 로고    scopus 로고
    • Retinoic acid signaling sensitizes hepatic stellate cells to NK cell killing via upregulation of NK cell activating ligand RAE1
    • Radaeva S, Wang L, Radaev S, Jeong WI, Park O, Gao B. Retinoic acid signaling sensitizes hepatic stellate cells to NK cell killing via upregulation of NK cell activating ligand RAE1. Am J Physiol Gastrointest Liver Physiol (2007) 293:G809-16. doi:10.1152/ajpgi.00212.2007
    • (2007) Am J Physiol Gastrointest Liver Physiol , vol.293 , pp. G809-G816
    • Radaeva, S.1    Wang, L.2    Radaev, S.3    Jeong, W.I.4    Park, O.5    Gao, B.6
  • 53
    • 49749145668 scopus 로고    scopus 로고
    • Senescence of activated stellate cells limits liver fibrosis
    • Krizhanovsky V, Yon M, Dickins RA, Hearn S, Simon J, Miething C, et al. Senescence of activated stellate cells limits liver fibrosis. Cell (2008) 134:657-67. doi:10.1016/j.cell.2008.06.049
    • (2008) Cell , vol.134 , pp. 657-667
    • Krizhanovsky, V.1    Yon, M.2    Dickins, R.A.3    Hearn, S.4    Simon, J.5    Miething, C.6
  • 54
    • 84860596931 scopus 로고    scopus 로고
    • NKp46-mediated killing of human and mouse hepatic stellate cells attenuates liver fibrosis
    • Gur C, Doron S, Kfir-Erenfeld S, Horwitz E, Abu-Tair L, Safadi R, et al. NKp46-mediated killing of human and mouse hepatic stellate cells attenuates liver fibrosis. Gut (2012) 61:885-93. doi:10.1136/gutjnl-2011-301400
    • (2012) Gut , vol.61 , pp. 885-893
    • Gur, C.1    Doron, S.2    Kfir-Erenfeld, S.3    Horwitz, E.4    Abu-Tair, L.5    Safadi, R.6
  • 56
    • 78651233786 scopus 로고    scopus 로고
    • Amelioration of hepatic fibrosis by NK cell activation
    • Muhanna N, Abu Tair L, Doron S, Amer J, Azzeh M, Mahamid M, et al. Amelioration of hepatic fibrosis by NK cell activation. Gut (2011) 60:90-8. doi:10.1136/gut.2010.211136
    • (2011) Gut , vol.60 , pp. 90-98
    • Muhanna, N.1    Abu Tair, L.2    Doron, S.3    Amer, J.4    Azzeh, M.5    Mahamid, M.6
  • 57
    • 0026782189 scopus 로고
    • Inhibition of rat hepatic lipocyte activation in culture by interferon-gamma
    • Rockey DC, Maher JJ, Jarnagin WR, Gabbiani G, Friedman SL. Inhibition of rat hepatic lipocyte activation in culture by interferon-gamma. Hepatology (1992) 16:776-84. doi:10.1002/hep.1840160325
    • (1992) Hepatology , vol.16 , pp. 776-784
    • Rockey, D.C.1    Maher, J.J.2    Jarnagin, W.R.3    Gabbiani, G.4    Friedman, S.L.5
  • 58
    • 33845644601 scopus 로고    scopus 로고
    • STAT1 inhibits liver fibrosis in mice by inhibiting stellate cell proliferation and stimulating NK cell cytotoxicity
    • Jeong WI, Park O, Radaeva S, Gao B. STAT1 inhibits liver fibrosis in mice by inhibiting stellate cell proliferation and stimulating NK cell cytotoxicity. Hepatology (2006) 44:1441-51. doi:10.1002/hep.21419
    • (2006) Hepatology , vol.44 , pp. 1441-1451
    • Jeong, W.I.1    Park, O.2    Radaeva, S.3    Gao, B.4
  • 59
    • 84969410090 scopus 로고    scopus 로고
    • Targeted therapies in liver fibrosis: combining the best parts of platelet-derived growth factor BB and interferon gamma
    • van Dijk F, Olinga P, Poelstra K, Beljaars L. Targeted therapies in liver fibrosis: combining the best parts of platelet-derived growth factor BB and interferon gamma. Front Med (2015) 2:72. doi:10.3389/fmed.2015.00072
    • (2015) Front Med , vol.2 , pp. 72
    • van Dijk, F.1    Olinga, P.2    Poelstra, K.3    Beljaars, L.4
  • 60
    • 77951861128 scopus 로고    scopus 로고
    • Interferon-alpha-induced TRAIL on natural killer cells is associated with control of hepatitis C virus infection
    • Stegmann KA, Bjorkstrom NK, Veber H, Ciesek S, Riese P, Wiegand J, et al. Interferon-alpha-induced TRAIL on natural killer cells is associated with control of hepatitis C virus infection. Gastroenterology (2010) 138:1885-97. doi:10.1053/j.gastro.2010.01.051
    • (2010) Gastroenterology , vol.138 , pp. 1885-1897
    • Stegmann, K.A.1    Bjorkstrom, N.K.2    Veber, H.3    Ciesek, S.4    Riese, P.5    Wiegand, J.6
  • 61
    • 80053593363 scopus 로고    scopus 로고
    • Early changes in natural killer cell function indicate virologic response to interferon therapy for hepatitis C
    • Ahlenstiel G, Edlich B, Hogdal LJ, Rotman Y, Noureddin M, Feld JJ, et al. Early changes in natural killer cell function indicate virologic response to interferon therapy for hepatitis C. Gastroenterology (2011) 141:1231-1239, 1239.e1. doi:10.1053/j.gastro.2011.06.069
    • (2011) Gastroenterology , vol.141 , pp. 1231-1239
    • Ahlenstiel, G.1    Edlich, B.2    Hogdal, L.J.3    Rotman, Y.4    Noureddin, M.5    Feld, J.J.6
  • 62
    • 84862993192 scopus 로고    scopus 로고
    • NK cells from HCV-infected patients effectively induce apoptosis of activated primary human hepatic stellate cells in a TRAIL-, FasL-and NKG2D-dependent manner
    • Glassner A, Eisenhardt M, Kramer B, Korner C, Coenen M, Sauerbruch T, et al. NK cells from HCV-infected patients effectively induce apoptosis of activated primary human hepatic stellate cells in a TRAIL-, FasL-and NKG2D-dependent manner. Lab Invest (2012) 92:967-77. doi:10.1038/labinvest.2012.54
    • (2012) Lab Invest , vol.92 , pp. 967-977
    • Glassner, A.1    Eisenhardt, M.2    Kramer, B.3    Korner, C.4    Coenen, M.5    Sauerbruch, T.6
  • 63
    • 37349108815 scopus 로고    scopus 로고
    • Abrogation of the antifibrotic effects of natural killer cells/interferon-gamma contributes to alcohol acceleration of liver fibrosis
    • Jeong WI, Park O, Gao B. Abrogation of the antifibrotic effects of natural killer cells/interferon-gamma contributes to alcohol acceleration of liver fibrosis. Gastroenterology (2008) 134:248-58. doi:10.1053/j.gastro.2007.09.034
    • (2008) Gastroenterology , vol.134 , pp. 248-258
    • Jeong, W.I.1    Park, O.2    Gao, B.3
  • 64
    • 79953752559 scopus 로고    scopus 로고
    • Suppression of innate immunity (natural killer cell/interferon-gamma) in the advanced stages of liver fibrosis in mice
    • Jeong WI, Park O, Suh YG, Byun JS, Park SY, Choi E, et al. Suppression of innate immunity (natural killer cell/interferon-gamma) in the advanced stages of liver fibrosis in mice. Hepatology (2011) 53:1342-51. doi:10.1002/hep.24190
    • (2011) Hepatology , vol.53 , pp. 1342-1351
    • Jeong, W.I.1    Park, O.2    Suh, Y.G.3    Byun, J.S.4    Park, S.Y.5    Choi, E.6
  • 65
    • 84859254888 scopus 로고    scopus 로고
    • TGF-beta1 down-regulation of NKG2D/DAP10 and 2B4/SAP expression on human NK cells contributes to HBV persistence
    • Sun C, Fu B, Gao Y, Liao X, Sun R, Tian Z, et al. TGF-beta1 down-regulation of NKG2D/DAP10 and 2B4/SAP expression on human NK cells contributes to HBV persistence. PLoS Pathog (2012) 8:e1002594. doi:10.1371/journal.ppat.1002594
    • (2012) PLoS Pathog , vol.8
    • Sun, C.1    Fu, B.2    Gao, Y.3    Liao, X.4    Sun, R.5    Tian, Z.6
  • 66
    • 84877139427 scopus 로고    scopus 로고
    • Hepatic stellate cells in liver development, regeneration, and cancer
    • Yin C, Evason KJ, Asahina K, Stainier DY. Hepatic stellate cells in liver development, regeneration, and cancer. J Clin Invest (2013) 123:1902-10. doi:10.1172/JCI66369
    • (2013) J Clin Invest , vol.123 , pp. 1902-1910
    • Yin, C.1    Evason, K.J.2    Asahina, K.3    Stainier, D.Y.4
  • 67
    • 84877076614 scopus 로고    scopus 로고
    • Natural killer and natural killer T cells in liver fibrosis
    • Gao B, Radaeva S. Natural killer and natural killer T cells in liver fibrosis. Biochim Biophys Acta (2013) 1832:1061-9. doi:10.1016/j.bbadis.2012.09.008
    • (2013) Biochim Biophys Acta , vol.1832 , pp. 1061-1069
    • Gao, B.1    Radaeva, S.2
  • 68
    • 84935488734 scopus 로고    scopus 로고
    • Immunosurveillance of the liver by intravascular effector CD8(+) T cells
    • Guidotti LG, Inverso D, Sironi L, Di Lucia P, Fioravanti J, Ganzer L, et al. Immunosurveillance of the liver by intravascular effector CD8(+) T cells. Cell (2015) 161:486-500. doi:10.1016/j.cell.2015.03.005
    • (2015) Cell , vol.161 , pp. 486-500
    • Guidotti, L.G.1    Inverso, D.2    Sironi, L.3    Di Lucia, P.4    Fioravanti, J.5    Ganzer, L.6
  • 70
    • 84864369008 scopus 로고    scopus 로고
    • Severe necroinflammatory reaction caused by natural killer cell-mediated Fas/Fas ligand interaction and dendritic cells in human hepatocyte chimeric mouse
    • Okazaki A, Hiraga N, Imamura M, Hayes CN, Tsuge M, Takahashi S, et al. Severe necroinflammatory reaction caused by natural killer cell-mediated Fas/Fas ligand interaction and dendritic cells in human hepatocyte chimeric mouse. Hepatology (2012) 56:555-66. doi:10.1002/hep.25651
    • (2012) Hepatology , vol.56 , pp. 555-566
    • Okazaki, A.1    Hiraga, N.2    Imamura, M.3    Hayes, C.N.4    Tsuge, M.5    Takahashi, S.6
  • 71
    • 84945293359 scopus 로고    scopus 로고
    • TLR7/8 agonists promote NK-DC cross-talk to enhance NK cell anti-tumor effects in hepatocellular carcinoma
    • Zhou Z, Yu X, Zhang J, Tian Z, Zhang C. TLR7/8 agonists promote NK-DC cross-talk to enhance NK cell anti-tumor effects in hepatocellular carcinoma. Cancer Lett (2015) 369(2):298-306. doi:10.1016/j.canlet.2015.09.017
    • (2015) Cancer Lett , vol.369 , Issue.2 , pp. 298-306
    • Zhou, Z.1    Yu, X.2    Zhang, J.3    Tian, Z.4    Zhang, C.5
  • 72
    • 84882845968 scopus 로고    scopus 로고
    • Impaired CD4(+) T cell stimulation of NK cell anti-fibrotic activity may contribute to accelerated liver fibrosis progression in HIV/HCV patients
    • Glassner A, Eisenhardt M, Kokordelis P, Kramer B, Wolter F, Nischalke HD, et al. Impaired CD4(+) T cell stimulation of NK cell anti-fibrotic activity may contribute to accelerated liver fibrosis progression in HIV/HCV patients. J Hepatol (2013) 59:427-33. doi:10.1016/j.jhep.2013.04.029
    • (2013) J Hepatol , vol.59 , pp. 427-433
    • Glassner, A.1    Eisenhardt, M.2    Kokordelis, P.3    Kramer, B.4    Wolter, F.5    Nischalke, H.D.6
  • 73
    • 84922233795 scopus 로고    scopus 로고
    • Regulatory CD4+ T cells modulate the interaction between NK cells and hepatic stellate cells by acting on either cell type
    • Langhans B, Alwan AW, Kramer B, Glassner A, Lutz P, Strassburg CP, et al. Regulatory CD4+ T cells modulate the interaction between NK cells and hepatic stellate cells by acting on either cell type. J Hepatol (2015) 62:398-404. doi:10.1016/j.jhep.2014.08.038
    • (2015) J Hepatol , vol.62 , pp. 398-404
    • Langhans, B.1    Alwan, A.W.2    Kramer, B.3    Glassner, A.4    Lutz, P.5    Strassburg, C.P.6
  • 74
    • 68149171396 scopus 로고    scopus 로고
    • Hepatocyte-specific NEMO deletion promotes NK/NKT cell-and TRAIL-dependent liver damage
    • Beraza N, Malato Y, Sander LE, Al-Masaoudi M, Freimuth J, Riethmacher D, et al. Hepatocyte-specific NEMO deletion promotes NK/NKT cell-and TRAIL-dependent liver damage. J Exp Med (2009) 206:1727-37. doi:10.1084/jem.20082152
    • (2009) J Exp Med , vol.206 , pp. 1727-1737
    • Beraza, N.1    Malato, Y.2    Sander, L.E.3    Al-Masaoudi, M.4    Freimuth, J.5    Riethmacher, D.6
  • 75
    • 73949112938 scopus 로고    scopus 로고
    • Increased killing of liver NK cells by Fas/Fas ligand and NKG2D/NKG2D ligand contributes to hepatocyte necrosis in virus-induced liver failure
    • Zou Y, Chen T, Han M, Wang H, Yan W, Song G, et al. Increased killing of liver NK cells by Fas/Fas ligand and NKG2D/NKG2D ligand contributes to hepatocyte necrosis in virus-induced liver failure. J Immunol (2010) 184:466-75. doi:10.4049/jimmunol.0900687
    • (2010) J Immunol , vol.184 , pp. 466-475
    • Zou, Y.1    Chen, T.2    Han, M.3    Wang, H.4    Yan, W.5    Song, G.6
  • 76
    • 84921834042 scopus 로고    scopus 로고
    • TRAIL-producing NK cells contribute to liver injury and related fibrogenesis in the context of GNMT deficiency
    • Fernandez-Alvarez S, Gutierrez-De Juan V, Zubiete-Franco I, Barbier-Torres L, Lahoz A, Pares A, et al. TRAIL-producing NK cells contribute to liver injury and related fibrogenesis in the context of GNMT deficiency. Lab Invest (2015) 95:223-36. doi:10.1038/labinvest.2014.151
    • (2015) Lab Invest , vol.95 , pp. 223-236
    • Fernandez-Alvarez, S.1    Gutierrez-De Juan, V.2    Zubiete-Franco, I.3    Barbier-Torres, L.4    Lahoz, A.5    Pares, A.6
  • 77
    • 84941948977 scopus 로고    scopus 로고
    • NKP30-B7-H6 interaction aggravates hepatocyte damage through up-regulation of interleukin-32 expression in hepatitis B virus-related acute-on-chronic liver failure
    • Zou Y, Bao J, Pan X, Lu Y, Liao S, Wang X, et al. NKP30-B7-H6 interaction aggravates hepatocyte damage through up-regulation of interleukin-32 expression in hepatitis B virus-related acute-on-chronic liver failure. PLoS One (2015) 10:e0134568. doi:10.1371/journal.pone.0134568
    • (2015) PLoS One , vol.10
    • Zou, Y.1    Bao, J.2    Pan, X.3    Lu, Y.4    Liao, S.5    Wang, X.6
  • 78
    • 40749156951 scopus 로고    scopus 로고
    • Activation of natural killer cells inhibits liver fibrosis: a novel strategy to treat liver fibrosis
    • Gao B, Radaeva S, Jeong WI. Activation of natural killer cells inhibits liver fibrosis: a novel strategy to treat liver fibrosis. Expert Rev Gastroenterol Hepatol (2007) 1:173-80. doi:10.1586/17474124.1.1.173
    • (2007) Expert Rev Gastroenterol Hepatol , vol.1 , pp. 173-180
    • Gao, B.1    Radaeva, S.2    Jeong, W.I.3
  • 79
    • 42449123606 scopus 로고    scopus 로고
    • Natural killer cell-directed therapies: moving from unexpected results to successful strategies
    • Terme M, Ullrich E, Delahaye NF, Chaput N, Zitvogel L. Natural killer cell-directed therapies: moving from unexpected results to successful strategies. Nat Immunol (2008) 9:486-94. doi:10.1038/ni1580
    • (2008) Nat Immunol , vol.9 , pp. 486-494
    • Terme, M.1    Ullrich, E.2    Delahaye, N.F.3    Chaput, N.4    Zitvogel, L.5
  • 80
    • 9644289366 scopus 로고    scopus 로고
    • Innate immune system plays a critical role in determining the progression and severity of acetaminophen hepatotoxicity
    • Liu ZX, Govindarajan S, Kaplowitz N. Innate immune system plays a critical role in determining the progression and severity of acetaminophen hepatotoxicity. Gastroenterology (2004) 127:1760-74. doi:10.1053/j.gastro.2004.08.053
    • (2004) Gastroenterology , vol.127 , pp. 1760-1774
    • Liu, Z.X.1    Govindarajan, S.2    Kaplowitz, N.3
  • 81
    • 51349122739 scopus 로고    scopus 로고
    • Pathogenic role of natural killer T and natural killer cells in acetaminophen-induced liver injury in mice is dependent on the presence of dimethyl sulfoxide
    • Masson MJ, Carpenter LD, Graf ML, Pohl LR. Pathogenic role of natural killer T and natural killer cells in acetaminophen-induced liver injury in mice is dependent on the presence of dimethyl sulfoxide. Hepatology (2008) 48:889-97. doi:10.1002/hep.22400
    • (2008) Hepatology , vol.48 , pp. 889-897
    • Masson, M.J.1    Carpenter, L.D.2    Graf, M.L.3    Pohl, L.R.4
  • 82
    • 84876561418 scopus 로고    scopus 로고
    • IL-22-producing RORgammat-dependent innate lymphoid cells play a novel protective role in murine acute hepatitis
    • Matsumoto A, Kanai T, Mikami Y, Chu PS, Nakamoto N, Ebinuma H, et al. IL-22-producing RORgammat-dependent innate lymphoid cells play a novel protective role in murine acute hepatitis. PLoS One (2013) 8:e62853. doi:10.1371/journal.pone.0062853
    • (2013) PLoS One , vol.8
    • Matsumoto, A.1    Kanai, T.2    Mikami, Y.3    Chu, P.S.4    Nakamoto, N.5    Ebinuma, H.6
  • 83
    • 84882580383 scopus 로고    scopus 로고
    • Interleukin-33-dependent innate lymphoid cells mediate hepatic fibrosis
    • McHedlidze T, Waldner M, Zopf S, Walker J, Rankin AL, Schuchmann M, et al. Interleukin-33-dependent innate lymphoid cells mediate hepatic fibrosis. Immunity (2013) 39:357-71. doi:10.1016/j.immuni.2013.07.018
    • (2013) Immunity , vol.39 , pp. 357-371
    • McHedlidze, T.1    Waldner, M.2    Zopf, S.3    Walker, J.4    Rankin, A.L.5    Schuchmann, M.6


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