CXC chemokine ligand 16 promotes integrin-mediated adhesion of liver-infiltrating lymphocytes to cholangiocytes and hepatocytes within the inflamed human liver

Journal of Immunology

Volumn 174, Issue 2, 2005, Pages 1055-1062

  Heydtmann, Mathis ^a   Lalor, Patricia F ^a   Eksteen, J Albertus ^a   Hübscher, Stefan G ^a   Briskin, Mike ^b   Adams, David H ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b MILLENNIUM PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; CD4 ANTIGEN; CD56 ANTIGEN; CD8 ANTIGEN; CHEMOKINE; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CXCR6; PROTEIN CXC CHEMOKINE LIGAND 16; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ARTICLE; BILE DUCT; CELL ADHESION; CELL DESTRUCTION; CELL MEMBRANE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENDOTHELIUM CELL; HEPATITIS; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; IMMUNE RESPONSE; LIVER; LIVER CELL; LIVER INJURY; LYMPHOCYTE; LYMPHOCYTE ACTIVATION; PORTAL VEIN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN INTERACTION; T LYMPHOCYTE;

EID: 11844294973     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.174.2.1055     Document Type: Article

References (34)

1. Lauer, G. M., and B. D. Walker. 2001. Hepatitis C virus infection. N. Engl. J. Med. 345:41.
2. + T cells in chronic hepatitis C virus infection. J. Immunol. 169:3447.
3. Willberg, C., E. Barnes, and P. Klenerman. 2003. HCV immunology: death and the maiden T cell. Cell Death Differ. 10(Suppl. 1):S39.
4. Heydtmann, M., P. Shields, G. McCaughan, and D. Adams. 2001. Cytokines and chemokines in the immune response to hepatitis C infection. Curr. Opin. Infect. Dis. 14:279.
5. Campbell, D. J., C. H. Kim, and E. C. Butcher. 2003. Chemokines in the systemic organization of immunity. Immunol. Rev. 195:58.
6. Baltus, T., K. S. Weber, Z. Johnson, A. E. Proudfoot, and C. Weber. 2003. Oligomerization of RANTES is required for CCR1-mediated arrest but not CCR5-mediated transmigration of leukocytes on inflamed endothelium. Blood 102:1985.
7. Johnston, B., and E. C. Butcher. 2002. Chemokines in rapid leukocyte adhesion triggering and migration. Semin. Immunol. 14:83.
8. Foxman, E. F., E. J. Kunkel, and E. C. Butcher. 1999. Integrating conflicting chemotactic signals: the role of memory in leukocyte navigation. J. Cell Biol. 147:577.
9. Matloubian, M., A. David, S. Engel, J. E. Ryan, and J. G. Cyster. 2000. A transmembrane CXC chemokine is a ligand for HIV-coreceptor Bonzo. Nat. Immunol. 1:298.
10. Wilbanks, A., S. C. Zondlo, K. Murphy, S. Mak, D. Soler, P. Langdon, D. P. Andrew, L. Wu, and M. Briskin. 2001. Expression cloning of the strl33/bonzo/tymstr ligand reveals elements of CC, CXC, and CX3C chemokines. J. Immunol. 166:5145.
11. Sharron, M., S. Pohlmann, K. Price, E. Lolis, M. Tsang, F. Kirchhoff, R. W. Doms, and B. Lee. 2000. Expression and coreceptor activity of STRL33/Bonzo on primary peripheral blood lymphocytes. Blood 96:41.
12. + NK and NK-T peripheral blood lymphocytes identified by chemokine receptor expression repertoire. J. Immunol. 166:6477.
13. Unutmaz, D., W. Xiang, M. J. Sunshine, J. Campbell, E. Butcher, and D. R. Littman. 2000. The primate lentiviral receptor Bonzo/STRL33 is coordinately regulated with CCR5 and its expression pattern is conserved between human and mouse. J. Immunol. 165:3284.
14. Kim, C. H., E. J. Kunkel, J. Boisvert, B. Johnston, J. J. Campbell, M. C. Genovese, H. B. Greenberg, and E. C. Butcher. 2001. Bonzo/CXCR6 expression defines type 1-polarized T-cell subsets with extralymphoid tissue homing potential. J. Clin. Invest. 107:595.
15. Boisvert, J., E. J. Kunkel, J. J. Campbell, E. B. Keeffe, E. C. Butcher, and H. B. Greenberg. 2003. Liver-infiltrating lymphocytes in end-stage hepatitis C virus: subsets, activation status, and chemokine receptor phenotypes. J. Hepatol. 38:67.
16. Napoli, J., G. A. Bishop, P. H. McGuinness, D. M. Painter, and G. W. McCaughan. 1996. Progressive liver injury in chronic hepatitis C infection correlates with increased intrahepatic expression of Th1-associated cytokines. Hepatology 24:759.
17. Racanelli, V., and B. Rehermann. 2003. Hepatitis C virus infection: when silence is deception. Trends Immunol. 24:456.
18. Shields, P. L., C. M. Morland, M. Salmon, S. Qin, S. G. Hubscher, and D. H. Adams. 1999. Chemokine and chemokine receptor interactions provide a mechanism for selective T cell recruitment to specific liver compartments within hepatitis C-infected liver. J. Immunol. 163:6236.
19. Joplin, R. 1994. Isolation and culture of biliary epithelial cells. Gut 35:875.
20. Nussler, A. K., G. Vergani, S. M. Gollin, K. Dorko, S. M. Morris, Jr., A. J. Demetris, M. Nomoto, H. G. Beger, and S. C. Strom. 1999. Isolation and characterization of a human hepatic epithelial-like cell line (AKN-1) from a normal liver. In Vitro Cell. Dev. Biol. Anim. 35:190.
21. Lalor, P. F., S. Edwards, G. McNab, M. Salmi, S. Jalkanen, and D. H. Adams. 2002. Vascular adhesion protein-1 mediates adhesion and transmigration of lymphocytes on human hepatic endothelial cells. J. Immunol. 169:983.
22. Ismail, T., J. Howl, M. Wheatley, P. McMaster, J. M. Neuberger, and A. J. Strain. 1991. Growth of normal human hepatocytes in primary culture: effect of hormones and growth factors on DNA synthesis. Hepatology 14:1076.
23. Adams, D. H., S. G. Hubscher, J. Shaw, G. D. Johnson, C. Babbs, R. Rothlein, and J. M. Neuberger. 1991. Increased expression of intercellular adhesion molecule 1 on bile ducts in primary biliary cirrhosis and primary sclerosing cholangitis. Hepatology 14:426.
24. Mould, A. P., A. N. Garratt, J. A. Askari, S. K. Akiyama, and M. J. Humphries. 1995. Identification of a novel anti-integrin monoclonal antibody that recognizes a ligand-induced binding site epitope on the β1 subunit. FEBS Lett. 363:118.
25. 1. Proc. Natl. Acad. Sci. USA 90:9051.
26. Grant, A. J., S. Goddard, J. Ahmed-Choudhury, G. Reynolds, D. G. Jackson, M. Briskin, L. Wu, S. G. Hubscher, and D. H. Adams. 2002. Hepatic expression of secondary lymphoid chemokine (CCL21) promotes the development of portal-associated lymphoid tissue in chronic inflammatory liver disease. Am. J. Pathol. 160:1445.
27. Shimaoka, T., T. Nakayama, N. Fukumoto, N. Kume, S. Takahashi, J. Yamaguchi, M. Minami, K. Hayashida, T. Kita, J. Ohsumi, et al. 2004. Cell surface-anchored SR-PSOX/CXC chemokine ligand 16 mediates firm adhesion of CXC chemokine receptor 6-expressing cells. J. Leukocyte Biol. 75:267.
28. Bazan, J. F., K. B. Bacon, G. Hardiman, W. Wang, K. Soo, D. Rossi, D. R. Greaves, A. Zlotnik, and T. J. Schall. 1997. A new class of membrane-bound chemokine with a CX3C motif. Nature 385:640.
29. Yasoshima, M., Y. Nakanuma, K. Tsuneyama, J. Vandewater, and M. E. Gershwin. 1995. Immunohistochemical analysis of adhesion molecules in the microenvironment of portal tracts in relation to aberrant expression of PDC E2 and HLA-DR on the bile-ducts in primary biliary-cirrhosis. J. Pathol. 175:319.
30. Johnston, B., C. H. Kim, D. Soler, M. Emoto, and E. C. Butcher. 2003. Differential chemokine responses and homing patterns of murine TCR αβ NKT cell subsets. J. Immunol. 171:2960.
31. Probert, C. S., A. D. Christ, L. J. Saubermann, J. R. Turner, A. Chott, D. Carr-Locke, S. P. Balk, and R. S. Blumberg. 1997. Analysis of human common bile duct-associated T cells: evidence for oligoclonality, T cell clonal persistence, and epithelial cell recognition. J. Immunol. 158:1941.
32. Crispe, I. N. 2003. Hepatic T cells and liver tolerance. Nat. Rev. Immunol. 3:51.
33. Kenna, T., L. G. Mason, S. A. Porcelli, Y. Koezuka, J. E. Hegarty, C. O'Farrelly, and D. G. Doherty. 2003. NKT cells from normal and tumor-bearing human livers are phenotypically and functionally distinct from murine NKT cells. J. Immunol. 171:1775.
34. Wilhelm, M. J., J. Pratschke, F. Beato, M. Taal, M. Kusaka, W. W. Hancock, and N. L. Tilney. 2000. Activation of the heart by donor brain death accelerates acute rejection after transplantation. Circulation 102:2426.