Age-dependent defects of alpha-synuclein oligomer uptake in microglia and monocytes

Acta Neuropathologica

Volumn 131, Issue 3, 2016, Pages 379-391

  Bliederhaeuser, Corinna ^a   Grozdanov, Veselin ^a   Speidel, Anna ^b   Zondler, Lisa ^a   Ruf, Wolfgang P ^a   Bayer, Hanna ^a   Kiechle, Martin ^a   Feiler, Marisa S ^a   Freischmidt, Axel ^a   Brenner, David ^a   Witting, Anke ^a   Hengerer, Bastian ^b   Fändrich, Marcus ^a   Ludolph, Albert C ^a   Weishaupt, Jochen H ^a   Gillardon, Frank ^b   Danzer, Karin M ^a  

^a UNIVERSITY OF ULM   (Germany)

^b BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

Aging; Alpha synuclein; Exosomes; Microglia; Monocytes; Parkinson s disease

Indexed keywords

ALPHA SYNUCLEIN; OLIGOMER; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CELL ACTIVATION; CELL CULTURE; CELL ISOLATION; CELL SUBPOPULATION; CONTROLLED STUDY; CYTOKINE RELEASE; EXOSOME; GROUPS BY AGE; HUMAN; HUMAN CELL; MICROGLIA; MONOCYTE; MOUSE; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN FOLDING; ANIMAL; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; IMMUNOBLOTTING; METABOLISM; PARKINSON DISEASE; PHYSIOLOGY; SIZE EXCLUSION CHROMATOGRAPHY;

AGING; ALPHA-SYNUCLEIN; ANIMALS; CELLS, CULTURED; CHROMATOGRAPHY, GEL; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXOSOMES; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNOBLOTTING; MICE; MICROGLIA; MONOCYTES; PARKINSON DISEASE; PHAGOCYTOSIS;

EID: 84958111077     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-015-1504-2     Document Type: Article

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