ATRIP Deacetylation by SIRT2 Drives ATR Checkpoint Activation by Promoting Binding to RPA-ssDNA

Cell Reports

Volumn 14, Issue 6, 2016, Pages 1435-1447

  Zhang, Hui ^a   Head, PamelaSara E ^a   Daddacha, Waaqo ^a   Park, Seong Hoon ^b   Li, Xingzhe ^a   Pan, Yunfeng ^a   Madden, Matthew Z ^a   Duong, Duc M ^a   Xie, Maohua ^a   Yu, Bing ^a   Warren, Matthew D ^a   Liu, Elaine A ^a   Dhere, Vishal R ^a   Li, Chunyang ^a   Pradilla, Ivan ^a   Torres, Mylin A ^a   Wang, Ya ^a   Dynan, William S ^a   Doetsch, Paul W ^a   Deng, Xingming ^a   Seyfried, Nicholas T ^a   Gius, David ^b   Yu, David S ^a   more..

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Acetylome; ATR; ATRIP; Cell cycle; Checkpoint; DNA damage response; DNA repair; DNA replication; Metabolism; Replication stress; SIRT2; Sirtuin

Indexed keywords

ATR INTERACTING PROTEIN; ATR PROTEIN; DOUBLE STRANDED DNA; LYSINE; REGULATOR PROTEIN; REPLICATION FACTOR A; SIRTUIN 2; UNCLASSIFIED DRUG; ATM PROTEIN; ATR PROTEIN, HUMAN; ATRIP PROTEIN, HUMAN; DNA BINDING PROTEIN; PROTEIN BINDING; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SINGLE STRANDED DNA; SIRT2 PROTEIN, HUMAN;

ARTICLE; AUTOPHOSPHORYLATION; BIOACCUMULATION; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; DEACETYLATION; DNA DAMAGE; DNA REPLICATION; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; ACETYLATION; CELL CYCLE CHECKPOINT; GENE EXPRESSION REGULATION; GENETICS; HCT 116 CELL LINE; HEK293 CELL LINE; HELA CELL LINE; METABOLISM; PHOSPHORYLATION; TUMOR CELL LINE;

ACETYLATION; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ATAXIA TELANGIECTASIA MUTATED PROTEINS; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; DNA DAMAGE; DNA REPLICATION; DNA, SINGLE-STRANDED; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; HCT116 CELLS; HEK293 CELLS; HELA CELLS; HUMANS; PHOSPHORYLATION; PROTEIN BINDING; REPLICATION PROTEIN A; SIGNAL TRANSDUCTION; SIRTUIN 2;

EID: 84958102018     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2016.01.018     Document Type: Article

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