-
1
-
-
84921060015
-
Global distribution and prevalence of hepatitis C virus genotypes
-
Messina JP, Humphreys I, Flaxman A, Brown A, Cooke GS, Pybus OG, et al. Global distribution and prevalence of hepatitis C virus genotypes. Hepatology 2015;61:77-87.
-
(2015)
Hepatology
, vol.61
, pp. 77-87
-
-
Messina, J.P.1
Humphreys, I.2
Flaxman, A.3
Brown, A.4
Cooke, G.S.5
Pybus, O.G.6
-
2
-
-
84879113095
-
Chronic hepatitis C virus (HCV) disease burden and cost in the United States
-
Razavi H, Elkhoury AC, Elbasha E, Estes C, Pasini K, Poynard T, et al. Chronic hepatitis C virus (HCV) disease burden and cost in the United States. Hepatology 2013;57:2164-2170.
-
(2013)
Hepatology
, vol.57
, pp. 2164-2170
-
-
Razavi, H.1
Elkhoury, A.C.2
Elbasha, E.3
Estes, C.4
Pasini, K.5
Poynard, T.6
-
3
-
-
84855388574
-
Novel adenovirus-based vaccines induce broad and sustained T cell responses to HCV in man
-
115ra1
-
Barnes E, Folgori A, Capone S, Swadling L, Aston S, Kurioka A, et al. Novel adenovirus-based vaccines induce broad and sustained T cell responses to HCV in man. Sci Transl Med 2012;4:115ra1.
-
(2012)
Sci Transl Med
, vol.4
-
-
Barnes, E.1
Folgori, A.2
Capone, S.3
Swadling, L.4
Aston, S.5
Kurioka, A.6
-
4
-
-
84908876253
-
A human vaccine strategy based on chimpanzee adenoviral and MVA vectors that primes, boosts, and sustains functional HCV-specific T cell memory
-
261ra153
-
Swadling L, Capone S, Antrobus RD, Brown A, Richardson R, Newell EW, et al. A human vaccine strategy based on chimpanzee adenoviral and MVA vectors that primes, boosts, and sustains functional HCV-specific T cell memory. Sci Transl Med 2014;6:261ra153.
-
(2014)
Sci Transl Med
, vol.6
-
-
Swadling, L.1
Capone, S.2
Antrobus, R.D.3
Brown, A.4
Richardson, R.5
Newell, E.W.6
-
5
-
-
3042715432
-
Distinct MHC class I and II alleles are associated with hepatitis C viral clearance, originating from a single source
-
McKiernan SM, Hagan R, Curry M, McDonald GS, Kelly A, Nolan N, et al. Distinct MHC class I and II alleles are associated with hepatitis C viral clearance, originating from a single source. Hepatology 2004;40:108-114.
-
(2004)
Hepatology
, vol.40
, pp. 108-114
-
-
McKiernan, S.M.1
Hagan, R.2
Curry, M.3
McDonald, G.S.4
Kelly, A.5
Nolan, N.6
-
6
-
-
0142178211
-
HCV persistence and immune evasion in the absence of memory T cell help
-
Grakoui A, Shoukry NH, Woollard DJ, Han JH, Hanson HL, Ghrayeb J, et al. HCV persistence and immune evasion in the absence of memory T cell help. Science 2003;302:659-662.
-
(2003)
Science
, vol.302
, pp. 659-662
-
-
Grakoui, A.1
Shoukry, N.H.2
Woollard, D.J.3
Han, J.H.4
Hanson, H.L.5
Ghrayeb, J.6
-
9
-
-
17644444485
-
Analysis of successful immune responses in persons infected with hepatitis C virus
-
Lechner F, Wong DK, Dunbar PR, Chapman R, Chung RT, Dohrenwend P, et al. Analysis of successful immune responses in persons infected with hepatitis C virus. J Exp Med 2000;191:1499-1512.
-
(2000)
J Exp Med
, vol.191
, pp. 1499-1512
-
-
Lechner, F.1
Wong, D.K.2
Dunbar, P.R.3
Chapman, R.4
Chung, R.T.5
Dohrenwend, P.6
-
10
-
-
4444354594
-
High resolution analysis of cellular immune responses in resolved and persistent hepatitis C virus infection
-
Lauer GM, Barnes E, Lucas M, Timm J, Ouchi K, Kim AY, et al. High resolution analysis of cellular immune responses in resolved and persistent hepatitis C virus infection. Gastroenterology 2004;127:924-936.
-
(2004)
Gastroenterology
, vol.127
, pp. 924-936
-
-
Lauer, G.M.1
Barnes, E.2
Lucas, M.3
Timm, J.4
Ouchi, K.5
Kim, A.Y.6
-
12
-
-
33947421722
-
Dysfunction and functional restoration of HCV-specific CD8 responses in chronic hepatitis C virus infection
-
Penna A, Pilli M, Zerbini A, Orlandini A, Mezzadri S, Sacchelli L, et al. Dysfunction and functional restoration of HCV-specific CD8 responses in chronic hepatitis C virus infection. Hepatology 2007;45:588-601.
-
(2007)
Hepatology
, vol.45
, pp. 588-601
-
-
Penna, A.1
Pilli, M.2
Zerbini, A.3
Orlandini, A.4
Mezzadri, S.5
Sacchelli, L.6
-
13
-
-
84859436059
-
Sustained viral load reduction in treatment-naive HCV genotype 1 infected patients after therapeutic peptide vaccination
-
Klade CS, Schuller E, Boehm T, von Gabain A, Manns MP. Sustained viral load reduction in treatment-naive HCV genotype 1 infected patients after therapeutic peptide vaccination. Vaccine 2012;30:2943-2950.
-
(2012)
Vaccine
, vol.30
, pp. 2943-2950
-
-
Klade, C.S.1
Schuller, E.2
Boehm, T.3
von Gabain, A.4
Manns, M.P.5
-
14
-
-
68649126284
-
GI-5005, a yeast vector vaccine expressing an NS3-core fusion protein for chronic HCV infection
-
Habersetzer F, Baumert TF, Stoll-Keller F. GI-5005, a yeast vector vaccine expressing an NS3-core fusion protein for chronic HCV infection. Curr Opin Mol Ther 2009;11:456-462.
-
(2009)
Curr Opin Mol Ther
, vol.11
, pp. 456-462
-
-
Habersetzer, F.1
Baumert, T.F.2
Stoll-Keller, F.3
-
15
-
-
77957756030
-
A phase I clinical trial of dendritic cell immunotherapy in HCV-infected individuals
-
Gowans EJ, Roberts S, Jones K, Dinatale I, Latour PA, Chua B, et al. A phase I clinical trial of dendritic cell immunotherapy in HCV-infected individuals. J Hepatol 2010;53:599-607.
-
(2010)
J Hepatol
, vol.53
, pp. 599-607
-
-
Gowans, E.J.1
Roberts, S.2
Jones, K.3
Dinatale, I.4
Latour, P.A.5
Chua, B.6
-
16
-
-
60349132278
-
Immunogenicity of CIGB-230, a therapeutic DNA vaccine preparation, in HCV-chronically infected individuals in a phase I clinical trial
-
Alvarez-Lajonchere L, Shoukry NH, Gra B, Amador-Canizares Y, Helle F, Bedard N, et al. Immunogenicity of CIGB-230, a therapeutic DNA vaccine preparation, in HCV-chronically infected individuals in a phase I clinical trial. J Viral Hepat 2009;16:156-167.
-
(2009)
J Viral Hepat
, vol.16
, pp. 156-167
-
-
Alvarez-Lajonchere, L.1
Shoukry, N.H.2
Gra, B.3
Amador-Canizares, Y.4
Helle, F.5
Bedard, N.6
-
17
-
-
84902991292
-
Efficacy of immunotherapy with TG4040, peg-interferon, and RIBavirin in a phase 2 study of patients with chronic HCV infection
-
Di Bisceglie AM, Janczweska-Kazek E, Habersetzer F, Mazur W, Stanciu C, Carreno V, et al. Efficacy of immunotherapy with TG4040, peg-interferon, and RIBavirin in a phase 2 study of patients with chronic HCV infection. Gastroenterology 2014;147:119-131.
-
(2014)
Gastroenterology
, vol.147
, pp. 119-131
-
-
Di Bisceglie, A.M.1
Janczweska-Kazek, E.2
Habersetzer, F.3
Mazur, W.4
Stanciu, C.5
Carreno, V.6
-
18
-
-
80051490030
-
A poxvirus vaccine is safe, induces T-cell responses, and decreases viral load in patients with chronic hepatitis C
-
Habersetzer F, Honnet G, Bain C, Maynard-Muet M, Leroy V, Zarski JP, et al. A poxvirus vaccine is safe, induces T-cell responses, and decreases viral load in patients with chronic hepatitis C. Gastroenterology 2011;141:890-899.
-
(2011)
Gastroenterology
, vol.141
, pp. 890-899
-
-
Habersetzer, F.1
Honnet, G.2
Bain, C.3
Maynard-Muet, M.4
Leroy, V.5
Zarski, J.P.6
-
19
-
-
21644453108
-
Low CD8 T-cell proliferative potential and high viral load limit the effectiveness of therapeutic vaccination
-
Wherry EJ, Blattman JN, Ahmed R. Low CD8 T-cell proliferative potential and high viral load limit the effectiveness of therapeutic vaccination. J Virol 2005;79:8960-8968.
-
(2005)
J Virol
, vol.79
, pp. 8960-8968
-
-
Wherry, E.J.1
Blattman, J.N.2
Ahmed, R.3
-
20
-
-
84855372641
-
Vaccine vectors derived from a large collection of simian adenoviruses induce potent cellular immunity across multiple species
-
115ra2
-
Colloca S, Barnes E, Folgori A, Ammendola V, Capone S, Cirillo A, et al. Vaccine vectors derived from a large collection of simian adenoviruses induce potent cellular immunity across multiple species. Sci Transl Med 2012;4:115ra2.
-
(2012)
Sci Transl Med
, vol.4
-
-
Colloca, S.1
Barnes, E.2
Folgori, A.3
Ammendola, V.4
Capone, S.5
Cirillo, A.6
-
21
-
-
12144291311
-
Quantitative adenovirus neutralization assays based on the secreted alkaline phosphatase reporter gene: application in epidemiologic studies and in the design of adenovector vaccines
-
Aste-AmŽzaga M, Bett AJ, Wang F, Casimiro DR, Antonello JM, Patel DK, et al. Quantitative adenovirus neutralization assays based on the secreted alkaline phosphatase reporter gene: application in epidemiologic studies and in the design of adenovector vaccines. Hum Gene Ther 2004;15:293-304.
-
(2004)
Hum Gene Ther
, vol.15
, pp. 293-304
-
-
Aste-AmŽzaga, M.1
Bett, A.J.2
Wang, F.3
Casimiro, D.R.4
Antonello, J.M.5
Patel, D.K.6
-
22
-
-
84877985241
-
Favourable" IL28B polymorphisms are associated with a marked increase in baseline viral load in hepatitis C virus subtype 3a infection and do not predict a sustained virological response after 24 weeks of therapy
-
Bucci C, von Delft A, Christian A, Flemming VM, Harrison A, Halliday J, et al. "Favourable" IL28B polymorphisms are associated with a marked increase in baseline viral load in hepatitis C virus subtype 3a infection and do not predict a sustained virological response after 24 weeks of therapy. J Gen Virol 2013;94:1259-1265.
-
(2013)
J Gen Virol
, vol.94
, pp. 1259-1265
-
-
Bucci, C.1
von Delft, A.2
Christian, A.3
Flemming, V.M.4
Harrison, A.5
Halliday, J.6
-
23
-
-
84867017596
-
HCV genotype-3a T cell immunity: specificity, function and impact of therapy
-
Humphreys IS, von Delft A, Brown A, Hibbert L, Collier JD, Foster GR, et al. HCV genotype-3a T cell immunity: specificity, function and impact of therapy. Gut 2012;61:1589-1599.
-
(2012)
Gut
, vol.61
, pp. 1589-1599
-
-
Humphreys, I.S.1
von Delft, A.2
Brown, A.3
Hibbert, L.4
Collier, J.D.5
Foster, G.R.6
-
24
-
-
19944428565
-
CD8 epitope escape and reversion in acute HCV infection
-
Timm J, Lauer GM, Kavanagh DG, Sheridan I, Kim AY, Lucas M, et al. CD8 epitope escape and reversion in acute HCV infection. J Exp Med 2004;200:1593-1604.
-
(2004)
J Exp Med
, vol.200
, pp. 1593-1604
-
-
Timm, J.1
Lauer, G.M.2
Kavanagh, D.G.3
Sheridan, I.4
Kim, A.Y.5
Lucas, M.6
-
26
-
-
70349423481
-
Visualizing hepatitis C virus infections in human liver by two-photon microscopy
-
Liang Y, Shilagard T, Xiao SY, Snyder N, Lau D, Cicalese L, et al. Visualizing hepatitis C virus infections in human liver by two-photon microscopy. Gastroenterology 2009;137:1448-1458.
-
(2009)
Gastroenterology
, vol.137
, pp. 1448-1458
-
-
Liang, Y.1
Shilagard, T.2
Xiao, S.Y.3
Snyder, N.4
Lau, D.5
Cicalese, L.6
-
27
-
-
24944509220
-
T cells and viral persistence: lessons from diverse infections
-
Klenerman P, Hill A. T cells and viral persistence: lessons from diverse infections. Nat Immunol 2005;6:873-879.
-
(2005)
Nat Immunol
, vol.6
, pp. 873-879
-
-
Klenerman, P.1
Hill, A.2
-
28
-
-
65649113943
-
Cellular immune responses during high-dose interferon-alpha induction therapy for hepatitis C virus infection
-
Barnes E, Gelderblom HC, Humphreys I, Semmo N, Reesink HW, Beld MG, et al. Cellular immune responses during high-dose interferon-alpha induction therapy for hepatitis C virus infection. J Infect Dis 2009;199:819-828.
-
(2009)
J Infect Dis
, vol.199
, pp. 819-828
-
-
Barnes, E.1
Gelderblom, H.C.2
Humphreys, I.3
Semmo, N.4
Reesink, H.W.5
Beld, M.G.6
-
29
-
-
4344574012
-
Impact of alpha interferon and ribavirin on the function of maturing dendritic cells
-
Barnes E, Salio M, Cerundolo V, Medlin J, Murphy S, Dusheiko G, et al. Impact of alpha interferon and ribavirin on the function of maturing dendritic cells. Antimicrob Agents Chemother 2004;48:3382-3389.
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 3382-3389
-
-
Barnes, E.1
Salio, M.2
Cerundolo, V.3
Medlin, J.4
Murphy, S.5
Dusheiko, G.6
-
30
-
-
23944467250
-
Adaptive immune responses in acute and chronic hepatitis C virus infection
-
Bowen DG, Walker CM. Adaptive immune responses in acute and chronic hepatitis C virus infection. Nature 2005;436:946-952.
-
(2005)
Nature
, vol.436
, pp. 946-952
-
-
Bowen, D.G.1
Walker, C.M.2
-
31
-
-
84861579810
-
Lack of full CD8 functional restoration after antiviral treatment for acute and chronic hepatitis C virus infection
-
Missale G, Pilli M, Zerbini A, Penna A, Ravanetti L, Barili V, et al. Lack of full CD8 functional restoration after antiviral treatment for acute and chronic hepatitis C virus infection. Gut 2012;61:1076-1084.
-
(2012)
Gut
, vol.61
, pp. 1076-1084
-
-
Missale, G.1
Pilli, M.2
Zerbini, A.3
Penna, A.4
Ravanetti, L.5
Barili, V.6
-
32
-
-
0032581491
-
Original antigenic sin impairs cytotoxic T lymphocyte responses to viruses bearing variant epitopes
-
Klenerman P, Zinkernagel RM. Original antigenic sin impairs cytotoxic T lymphocyte responses to viruses bearing variant epitopes. Nature 1998;394:482-485.
-
(1998)
Nature
, vol.394
, pp. 482-485
-
-
Klenerman, P.1
Zinkernagel, R.M.2
-
33
-
-
84920945715
-
Cross-reactivity of hepatitis C virus specific vaccine-induced T cells at immunodominant epitopes
-
Kelly C, Swadling L, Brown A, Capone S, Folgori A, Salio M, et al. Cross-reactivity of hepatitis C virus specific vaccine-induced T cells at immunodominant epitopes. Eur J Immunol 2015;45:309-316.
-
(2015)
Eur J Immunol
, vol.45
, pp. 309-316
-
-
Kelly, C.1
Swadling, L.2
Brown, A.3
Capone, S.4
Folgori, A.5
Salio, M.6
-
34
-
-
0037383592
-
Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment
-
Wherry EJ, Blattman JN, Murali-Krishna K, van der Most R, Ahmed R. Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment. J Virol 2003;77:4911-4927.
-
(2003)
J Virol
, vol.77
, pp. 4911-4927
-
-
Wherry, E.J.1
Blattman, J.N.2
Murali-Krishna, K.3
van der Most, R.4
Ahmed, R.5
-
36
-
-
44449125241
-
Hepatitis A and hepatitis B vaccination responses in persons with chronic hepatitis C infections: a review of the evidence and current recommendations
-
Buxton JA, Kim JH. Hepatitis A and hepatitis B vaccination responses in persons with chronic hepatitis C infections: a review of the evidence and current recommendations. Can J Infect Dis Med Microbiol 2008;19:197-202.
-
(2008)
Can J Infect Dis Med Microbiol
, vol.19
, pp. 197-202
-
-
Buxton, J.A.1
Kim, J.H.2
-
37
-
-
84856846467
-
+ T cell responses are primed during acute hepatitis C infection, but rapidly disappear from human blood with viral persistence
-
+ T cell responses are primed during acute hepatitis C infection, but rapidly disappear from human blood with viral persistence. J Exp Med 2012;209:61-75.
-
(2012)
J Exp Med
, vol.209
, pp. 61-75
-
-
Schulze zur Wiesch, J.1
Ciuffreda, D.2
Lewis-Ximenez, L.3
Kasprowicz, V.4
Nolan, B.E.5
Streeck, H.6
-
38
-
-
84874606648
-
Genome-wide association study of spontaneous resolution of hepatitis C virus infection: data from multiple cohorts
-
Duggal P, Thio CL, Wojcik GL, Goedert JJ, Mangia A, Latanich R, et al. Genome-wide association study of spontaneous resolution of hepatitis C virus infection: data from multiple cohorts. Ann Intern Med 2013;158:235-245.
-
(2013)
Ann Intern Med
, vol.158
, pp. 235-245
-
-
Duggal, P.1
Thio, C.L.2
Wojcik, G.L.3
Goedert, J.J.4
Mangia, A.5
Latanich, R.6
-
39
-
-
20144368978
-
Prospective evaluation of community-acquired acute-phase hepatitis C virus infection
-
Cox AL, Netski DM, Mosbruger T, Sherman SG, Strathdee S, Ompad D, et al. Prospective evaluation of community-acquired acute-phase hepatitis C virus infection. Clin Infect Dis 2005;40:951-958.
-
(2005)
Clin Infect Dis
, vol.40
, pp. 951-958
-
-
Cox, A.L.1
Netski, D.M.2
Mosbruger, T.3
Sherman, S.G.4
Strathdee, S.5
Ompad, D.6
-
40
-
-
84898669547
-
Ledipasvir and sofosbuvir for previously treated HCV genotype 1 infection
-
Afdhal N, Reddy KR, Nelson DR, Lawitz E, Gordon SC, Schiff E, et al. Ledipasvir and sofosbuvir for previously treated HCV genotype 1 infection. N Engl J Med 2014;370:1483-1493.
-
(2014)
N Engl J Med
, vol.370
, pp. 1483-1493
-
-
Afdhal, N.1
Reddy, K.R.2
Nelson, D.R.3
Lawitz, E.4
Gordon, S.C.5
Schiff, E.6
-
41
-
-
84880998187
-
Combination interventions to prevent HCV transmission among people who inject drugs: modeling the impact of antiviral treatment, needle and syringe programs, and opiate substitution therapy
-
Martin NK, Hickman M, Hutchinson SJ, Goldberg DJ, Vickerman P. Combination interventions to prevent HCV transmission among people who inject drugs: modeling the impact of antiviral treatment, needle and syringe programs, and opiate substitution therapy. Clin Infect Dis 2013;57(Suppl. 2):S39-S45.
-
(2013)
Clin Infect Dis
, vol.57
, pp. S39-S45
-
-
Martin, N.K.1
Hickman, M.2
Hutchinson, S.J.3
Goldberg, D.J.4
Vickerman, P.5
-
42
-
-
84931378182
-
Successful interferon-free therapy of chronic hepatitis C virus infection normalizes natural killer cell function
-
Serti E, Chepa-Lotrea X, Kim YJ, Keane M, Fryzek N, Liang TJ, et al. Successful interferon-free therapy of chronic hepatitis C virus infection normalizes natural killer cell function. Gastroenterology 2015;149:190-200.
-
(2015)
Gastroenterology
, vol.149
, pp. 190-200
-
-
Serti, E.1
Chepa-Lotrea, X.2
Kim, Y.J.3
Keane, M.4
Fryzek, N.5
Liang, T.J.6
-
44
-
-
84878089612
-
A randomized, double-blind, placebo-controlled assessment of BMS-936558, a fully human monoclonal antibody to programmed death-1 (PD-1), in patients with chronic hepatitis C virus infection
-
Gardiner D, Lalezari J, Lawitz E, DiMicco M, Ghalib R, Reddy KR, et al. A randomized, double-blind, placebo-controlled assessment of BMS-936558, a fully human monoclonal antibody to programmed death-1 (PD-1), in patients with chronic hepatitis C virus infection. PloS One 2013;8:e63818.
-
(2013)
PloS One
, vol.8
-
-
Gardiner, D.1
Lalezari, J.2
Lawitz, E.3
DiMicco, M.4
Ghalib, R.5
Reddy, K.R.6
|