메뉴 건너뛰기




Volumn 9, Issue 2, 2016, Pages 401-413

CD161int CD8+ T cells: A novel population of highly functional, memory CD8+ T cells enriched within the gut

Author keywords

[No Author keywords available]

Indexed keywords

CD103 ANTIGEN; CD161 ANTIGEN; CD69 ANTIGEN; EOMESODERMIN; INTERLEUKIN 12; INTERLEUKIN 18; TRANSCRIPTION FACTOR T BET; ALPHA E INTEGRINS; ALPHA INTEGRIN; EOMES PROTEIN, HUMAN; KLRB1 PROTEIN, HUMAN; LECTIN; LEUKOCYTE ANTIGEN; NATURAL KILLER CELL LECTIN LIKE RECEPTOR SUBFAMILY B; PHORBOL 13 ACETATE 12 MYRISTATE; T BOX TRANSCRIPTION FACTOR; T LYMPHOCYTE ANTIGEN; T-BOX TRANSCRIPTION FACTOR TBX21;

EID: 84961794382     PISSN: 19330219     EISSN: 19353456     Source Type: Journal    
DOI: 10.1038/mi.2015.69     Document Type: Article
Times cited : (89)

References (48)
  • 1
    • 84862959581 scopus 로고    scopus 로고
    • Human MAIT and CD8 alpha alpha cells develop from a pool of type-17 precommitted CD8+ Tcells
    • Walker L.J, et al. Human MAIT and CD8 alpha alpha cells develop from a pool of type-17 precommitted CD8+ Tcells. Blood. 119, 422-433 (2012).
    • (2012) Blood , vol.119 , pp. 422-433
    • Walker, L.J.1
  • 2
    • 65249134069 scopus 로고    scopus 로고
    • Memory T cells in nonlymphoid tissue that provide enhanced local immunity during infection with herpes simplex virus
    • Gebhardt T, et al. Memory T cells in nonlymphoid tissue that provide enhanced local immunity during infection with herpes simplex virus. Nat. Immunol. 10, 524-530 (2009).
    • (2009) Nat. Immunol , vol.10 , pp. 524-530
    • Gebhardt, T.1
  • 3
    • 84862777442 scopus 로고    scopus 로고
    • Skin infection generates non-migratory memory CD8+ T(RM) cells providing global skin immunity
    • Jiang X, et al. Skin infection generates non-migratory memory CD8+ T(RM) cells providing global skin immunity. Nature. 483, 227-231 (2012).
    • (2012) Nature , vol.483 , pp. 227-231
    • Jiang, X.1
  • 4
    • 32044442312 scopus 로고    scopus 로고
    • Cutting edge: Gut microenvironment promotes differentiation of a unique memory CD8 T cell population
    • Masopust D, Vezys V, Wherry E.J, Barber D.L, & Ahmed R. Cutting edge: gut microenvironment promotes differentiation of a unique memory CD8 T cell population. J. Immunol. 176, 2079-2083 (2006).
    • (2006) J. Immunol , vol.176 , pp. 2079-2083
    • Masopust, D.1    Vezys, V.2    Wherry, E.J.3    Barber, D.L.4    Ahmed, R.5
  • 5
    • 0027966063 scopus 로고
    • Human NKRP1A A disulfide-linked homodimer of the C-Type lectin superfamily expressed by a subset of NK and T lymphocytes
    • Lanier L.L, Chang C, & Phillips J.H. Human NKRP1A. A disulfide-linked homodimer of the C-Type lectin superfamily expressed by a subset of NK and T lymphocytes. J. Immunol. 153, 2417-2428 (1994).
    • (1994) J. Immunol , vol.153 , pp. 2417-2428
    • Lanier, L.L.1    Chang, C.2    Phillips, J.H.3
  • 6
    • 29644443088 scopus 로고    scopus 로고
    • Expression of CD161 (NKR-P1A) defines subsets of human CD4 and CD8 T cells with different functional activities
    • Takahashi T, Dejbakhsh-Jones S, & Strober S. Expression of CD161 (NKR-P1A) defines subsets of human CD4 and CD8 T cells with different functional activities. J. Immunol. 176, 211-216 (2006).
    • (2006) J. Immunol , vol.176 , pp. 211-216
    • Takahashi, T.1    Dejbakhsh-Jones, S.2    Strober, S.3
  • 7
    • 0032772678 scopus 로고    scopus 로고
    • CD8+NKR-P1A+ T cells preferentially accumulate in human liver
    • Ishihara S, et al. CD8+NKR-P1A+ T cells preferentially accumulate in human liver. Eur. J. Immunol. 29, 2406-2413 (1999).
    • (1999) Eur. J. Immunol , vol.29 , pp. 2406-2413
    • Ishihara, S.1
  • 8
    • 4444298192 scopus 로고    scopus 로고
    • Diverse populations of T cells with NK cell receptors accumulate in the human intestine in health and in colorectal cancer
    • O'Keeffe J, et al. Diverse populations of T cells with NK cell receptors accumulate in the human intestine in health and in colorectal cancer. Eur. J. Immunol. 34, 2110-2119 (2004).
    • (2004) Eur. J. Immunol , vol.34 , pp. 2110-2119
    • O'Keeffe, J.1
  • 9
    • 77649253219 scopus 로고    scopus 로고
    • Analysis of CD161 expression on human CD8+ Tcells defines a distinct functional subset with tissue-homing properties
    • Billerbeck E, et al. Analysis of CD161 expression on human CD8+ Tcells defines a distinct functional subset with tissue-homing properties. Proc. Natl. Acad. Sci. USA. 107, 3006-3011 (2010).
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 3006-3011
    • Billerbeck, E.1
  • 10
    • 79251585935 scopus 로고    scopus 로고
    • Human MAIT cells are xenobiotic-resistant, tissuetargeted, CD161hi IL-17-secreting T cells
    • Dusseaux M, et al. Human MAIT cells are xenobiotic-resistant, tissuetargeted, CD161hi IL-17-secreting T cells. Blood. 117, 1250-1259 (2011).
    • (2011) Blood , vol.117 , pp. 1250-1259
    • Dusseaux, M.1
  • 11
    • 0033591698 scopus 로고    scopus 로고
    • An invariant T cell receptor alpha chain defines a novel TAPindependent major histocompatibility complex class Ib-restricted alpha/.beta T cell subpopulation in mammals
    • Tilloy F, et al. An invariant T cell receptor alpha chain defines a novel TAPindependent major histocompatibility complex class Ib-restricted alpha/.beta T cell subpopulation in mammals. J. Exp. Med. 189, 1907-1921 (1999).
    • (1999) J. Exp. Med , vol.189 , pp. 1907-1921
    • Tilloy, F.1
  • 12
    • 0037434974 scopus 로고    scopus 로고
    • Selection of evolutionarily conserved mucosal-Associated invariant T cells by MR1
    • Treiner E, et al. Selection of evolutionarily conserved mucosal-Associated invariant T cells by MR1. Nature. 422, 164-169 (2003).
    • (2003) Nature , vol.422 , pp. 164-169
    • Treiner, E.1
  • 13
    • 84885981736 scopus 로고    scopus 로고
    • Antigen-loadedMR1 tetramers define Tcell receptor heterogeneity in mucosal-Associated invariant T cells
    • Reantragoon R, et al. Antigen-loadedMR1 tetramers define Tcell receptor heterogeneity in mucosal-Associated invariant T cells. J. Exp. Med. 210, 2305-2320 (2013).
    • (2013) J. Exp. Med , vol.210 , pp. 2305-2320
    • Reantragoon, R.1
  • 14
    • 29144438027 scopus 로고    scopus 로고
    • Cutting Edge: Lectin-like transcript 1 is a ligand for the CD161 receptor
    • Aldemir H, et al. Cutting Edge: lectin-like transcript 1 is a ligand for the CD161 receptor. J. Immunol. 175, 7791-7795 (2005).
    • (2005) J. Immunol , vol.175 , pp. 7791-7795
    • Aldemir, H.1
  • 15
    • 45549100768 scopus 로고    scopus 로고
    • Functional consequences of interactions between human NKR-P1A and its ligand LLT1 expressed on activated dendritic cells and B cells
    • Rosen D.B, et al. Functional consequences of interactions between human NKR-P1A and its ligand LLT1 expressed on activated dendritic cells and B cells. J. Immunol. 180, 6508-6517 (2008).
    • (2008) J. Immunol , vol.180 , pp. 6508-6517
    • Rosen, D.B.1
  • 16
    • 80055065444 scopus 로고    scopus 로고
    • Induction of lectin-like transcript 1 (LLT1) protein cell surface expression by pathogens and interferon-g contributes to modulate immune responses
    • Germain C, et al. Induction of lectin-like transcript 1 (LLT1) protein cell surface expression by pathogens and interferon-g contributes to modulate immune responses. J. Biol. Chem. 286, 37964-37975 (2011).
    • (2011) J. Biol. Chem , vol.286 , pp. 37964-37975
    • Germain, C.1
  • 17
    • 0032494097 scopus 로고    scopus 로고
    • CD161 (NKR-P1A) costimulation of CD1d-dependent activation of human T cells expressing invariant Va24JaQ T cell receptor a chains
    • Exley M, Porcelli S, Furman M, Garcia J, & Balk S. CD161 (NKR-P1A) costimulation of CD1d-dependent activation of human T cells expressing invariant Va24JaQ T cell receptor a chains. J. Exp. Med. 188, 867-876 (1998).
    • (1998) J. Exp. Med , vol.188 , pp. 867-876
    • Exley, M.1    Porcelli, S.2    Furman, M.3    Garcia, J.4    Balk, S.5
  • 18
    • 77956124982 scopus 로고    scopus 로고
    • CD161 is a marker of all human IL-17-producing T-cell subsets and is induced by RORC
    • Maggi L, et al. CD161 is a marker of all human IL-17-producing T-cell subsets and is induced by RORC. Eur. J. Immunol. 40, 2174-2181 (2010).
    • (2010) Eur. J. Immunol , vol.40 , pp. 2174-2181
    • Maggi, L.1
  • 19
    • 84919777275 scopus 로고    scopus 로고
    • CD161 defines a transcriptional and functional phenotype across distinct human Tcell lineages
    • Fergusson J.R, et al. CD161 defines a transcriptional and functional phenotype across distinct human Tcell lineages. Cell Rep. 9, 1-14 (2014).
    • (2014) Cell Rep , vol.9 , pp. 1-14
    • Fergusson, J.R.1
  • 20
    • 84892453502 scopus 로고    scopus 로고
    • CD161+ +cD8+ T cells, including the MAIT cell subset, are specifically activated by IL-12+IL-18 in a TCR-independent manner
    • Ussher J.E, et al. CD161+ +CD8+ T cells, including the MAIT cell subset, are specifically activated by IL-12+IL-18 in a TCR-independent manner. Eur. J. Immunol. 44, 195-203 (2014).
    • (2014) Eur. J. Immunol , vol.44 , pp. 195-203
    • Ussher, J.E.1
  • 21
    • 0033554726 scopus 로고    scopus 로고
    • Two subsets of memory T lymphocytes with distinct homing potentials
    • Sallusto F, Lenig D, Forster R, Lipp M, & Lanzavecchia A. Two subsets of memory T lymphocytes with distinct homing potentials. Nature. 401, 708-712 (1999).
    • (1999) Nature , vol.401 , pp. 708-712
    • Sallusto, F.1    Lenig, D.2    Forster, R.3    Lipp, M.4    Lanzavecchia, A.5
  • 22
    • 65949112929 scopus 로고    scopus 로고
    • Stepwise development of MAITcells in mouse and human
    • Martin E, et al. Stepwise development of MAITcells in mouse and human. PLoS Biol. 7, e54 (2009).
    • (2009) PLoS Biol , vol.7 , pp. e54
    • Martin, E.1
  • 23
    • 84872772721 scopus 로고    scopus 로고
    • Distribution and compartmentalization of human circulating and tissue-resident memory T cell subsets
    • Sathaliyawala T, et al. Distribution and compartmentalization of human circulating and tissue-resident memory T cell subsets. Immunity. 38, 187-197 (2013).
    • (2013) Immunity , vol.38 , pp. 187-197
    • Sathaliyawala, T.1
  • 24
    • 84875466830 scopus 로고    scopus 로고
    • IL-7 licenses activation of human liver intrasinusoidal mucosal-Associated invariant Tcells
    • Tang X.-Z, et al. IL-7 licenses activation of human liver intrasinusoidal mucosal-Associated invariant Tcells. J. Immunol. 190, 3142-3152 (2013).
    • (2013) J. Immunol , vol.190 , pp. 3142-3152
    • Tang, X.-Z.1
  • 25
    • 0027944111 scopus 로고
    • Adhesion between epithelial cells and T lymphocytes mediated by E-cadherin and the alphaEbeta7 integrin
    • Cepek K.L, et al. Adhesion between epithelial cells and T lymphocytes mediated by E-cadherin and the alphaEbeta7 integrin. Nature. 372, 190-193 (1994).
    • (1994) Nature , vol.372 , pp. 190-193
    • Cepek, K.L.1
  • 26
    • 84888008030 scopus 로고    scopus 로고
    • The developmental pathway for CD103(+)CD8+ tissue-resident memory T cells of skin
    • Mackay L.K, et al. The developmental pathway for CD103(+)CD8+ tissue-resident memory T cells of skin. Nat. Immunol. 14, 1294-1301 (2013).
    • (2013) Nat. Immunol , vol.14 , pp. 1294-1301
    • Mackay, L.K.1
  • 27
    • 84918506186 scopus 로고    scopus 로고
    • Tissue-resident memory T cells
    • Schenkel J.M, & Masopust D. Tissue-resident memory T cells. Immunity. 41, 886-897 (2014).
    • (2014) Immunity , vol.41 , pp. 886-897
    • Schenkel, J.M.1    Masopust, D.2
  • 28
    • 70449474686 scopus 로고    scopus 로고
    • A distinct subset of self-renewing human memory CD8+ T cells survives cytotoxic chemotherapy
    • Turtle C.J, Swanson H.M, Fujii N, Estey E.H, & Riddell S.R. A distinct subset of self-renewing human memory CD8+ T cells survives cytotoxic chemotherapy. Immunity. 31, 834-844 (2009).
    • (2009) Immunity , vol.31 , pp. 834-844
    • Turtle, C.J.1    Swanson, H.M.2    Fujii, N.3    Estey, E.H.4    Riddell, S.R.5
  • 30
    • 55949116720 scopus 로고    scopus 로고
    • Phenotype and function of human T lymphocyte subsets: Consensus and issues
    • Appay V, van Lier R.a.W, Sallusto F, & Roederer M. Phenotype and function of human T lymphocyte subsets: consensus and issues. Cytometry A. 73, 975-983 (2008).
    • (2008) Cytometry A , vol.73 , pp. 975-983
    • Appay, V.1    Van Lier Ra, W.2    Sallusto, F.3    Roederer, M.4
  • 31
    • 84922693685 scopus 로고    scopus 로고
    • MAITcells are licensed through granzyme exchange to kill bacterially sensitized targets
    • Kurioka A, et al. MAITcells are licensed through granzyme exchange to kill bacterially sensitized targets. Mucosal Immunol. 8, 429-440 (2015).
    • (2015) Mucosal Immunol , vol.8 , pp. 429-440
    • Kurioka, A.1
  • 33
    • 0242410712 scopus 로고    scopus 로고
    • Control of effector CD8+ T cell function by the transcription factor Eomesodermin
    • Pearce E.L, et al. Control of effector CD8+ T cell function by the transcription factor Eomesodermin. Science. 302, 1041-1043 (2003).
    • (2003) Science , vol.302 , pp. 1041-1043
    • Pearce, E.L.1
  • 34
    • 60549090859 scopus 로고    scopus 로고
    • Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs
    • Cruz-Guilloty F, et al. Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs. J. Exp. Med. 206, 51-59 (2009).
    • (2009) J. Exp. Med , vol.206 , pp. 51-59
    • Cruz-Guilloty, F.1
  • 35
    • 84855388574 scopus 로고    scopus 로고
    • Novel adenovirus-based vaccines induce broad and sustained T cell responses to HCV in man
    • Barnes E, et al. Novel adenovirus-based vaccines induce broad and sustained T cell responses to HCV in man. Sci. Transl. Med. 4, 1-11 (2012).
    • (2012) Sci. Transl. Med , vol.4 , pp. 1-11
    • Barnes, E.1
  • 36
    • 18844454267 scopus 로고    scopus 로고
    • HIV-specific IFN-gamma/IL-2-secreting CD8 T cells supportCD4-independent proliferation of HIV-1-specific CD8 Tcells
    • Zimmerli S.C, et al. HIV-specific IFN-gamma/IL-2-secreting CD8 T cells supportCD4-independent proliferation of HIV-1-specific CD8 Tcells. Proc. Natl. Acad. Sci. USA. 102, 7239-7244 (2005).
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 7239-7244
    • Zimmerli, S.C.1
  • 37
    • 33745091465 scopus 로고    scopus 로고
    • Functional signatures of protective antiviral T-cell immunity in human virus infections
    • Harari A, et al. Functional signatures of protective antiviral T-cell immunity in human virus infections. Immunol. Rev. 211, 236-254 (2006).
    • (2006) Immunol. Rev , vol.211 , pp. 236-254
    • Harari, A.1
  • 38
    • 85018193995 scopus 로고    scopus 로고
    • Chimpanzee adenovirus vector ebola vaccine -preliminary report
    • advance online publication, 26 November 2014
    • Ledgerwood J.E, et al. Chimpanzee adenovirus vector ebola vaccine -preliminary report. N. Engl. J. Med, advance online publication, 26 November 2014 (doi:10.1056/NEJMoa1410863).
    • N. Engl. J. Med
    • Ledgerwood, J.E.1
  • 39
    • 84918836018 scopus 로고    scopus 로고
    • Mucosal-Associated invariant T-cells: New players in anti-bacterial immunity
    • Ussher J.E, Klenerman P. &Willberg C.B. Mucosal-Associated invariant T-cells: new players in anti-bacterial immunity. Front. Immunol. 5, 450 (2014).
    • (2014) Front. Immunol , vol.5 , pp. 450
    • Ussher, J.E.1    Klenerman, P.2    Willberg, C.B.3
  • 40
    • 84907542588 scopus 로고    scopus 로고
    • Resident memory CD8 Tcells trigger protective innate and adaptive immune responses
    • Schenkel J.M, et al. Resident memory CD8 Tcells trigger protective innate and adaptive immune responses. Science. 346, 98-101 (2014).
    • (2014) Science , vol.346 , pp. 98-101
    • Schenkel, J.M.1
  • 41
    • 84907515251 scopus 로고    scopus 로고
    • Skin-resident memory CD8+ T cells trigger a state of tissue-wide pathogen alert
    • Ariotti S, et al. Skin-resident memory CD8+ T cells trigger a state of tissue-wide pathogen alert. Science. 346, 101-105 (doi:10.1126/.science.1254803) (2014).
    • (2014) Science , vol.346 , pp. 101-105
    • Ariotti, S.1
  • 42
    • 63449133361 scopus 로고    scopus 로고
    • Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation
    • Kleinschek M.A, et al. Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation. J. Exp. Med. 206, 525-534 (2009).
    • (2009) J. Exp. Med , vol.206 , pp. 525-534
    • Kleinschek, M.A.1
  • 43
    • 84892536761 scopus 로고    scopus 로고
    • Pro-inflammatory human Th17 cells selectively express P-glycoprotein and are refractory to glucocorticoids
    • Ramesh R, et al. Pro-inflammatory human Th17 cells selectively express P-glycoprotein and are refractory to glucocorticoids. J. Exp. Med. 211, 89-104 (2014).
    • (2014) J. Exp. Med , vol.211 , pp. 89-104
    • Ramesh, R.1
  • 44
    • 49249135394 scopus 로고    scopus 로고
    • Human interleukin 17-producing cells originate from a CD161+CD4+ T cell precursor
    • Cosmi L, et al. Human interleukin 17-producing cells originate from a CD161+CD4+ T cell precursor. J. Exp. Med. 205, 1903-1916 (2008).
    • (2008) J. Exp. Med , vol.205 , pp. 1903-1916
    • Cosmi, L.1
  • 45
    • 39549087674 scopus 로고    scopus 로고
    • CD161 expression on hepatitis C virus-specific CD8+ T cells suggests a distinct pathway of T cell differentiation
    • Northfield J.W, et al. CD161 expression on hepatitis C virus-specific CD8+ T cells suggests a distinct pathway of T cell differentiation. Hepatology. 47, 396-406 (2008).
    • (2008) Hepatology , vol.47 , pp. 396-406
    • Northfield, J.W.1
  • 47
    • 7244224901 scopus 로고    scopus 로고
    • Frequent expression of the natural killer cell receptor KLRG1 in human cord blood Tcells: Correlation with replicative history
    • Marcolino I, et al. Frequent expression of the natural killer cell receptor KLRG1 in human cord blood Tcells: correlation with replicative history. Eur. J. Immunol. 34, 2672-2680 (2004).
    • (2004) Eur. J. Immunol , vol.34 , pp. 2672-2680
    • Marcolino, I.1
  • 48
    • 27344435774 scopus 로고    scopus 로고
    • Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide
    • Subramanian A, et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide. Proc. Natl. Acad. Sci. USA. 102, 15545-15550 (2005).
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 15545-15550
    • Subramanian, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.