Metabolomics screening identifies reduced L-carnitine to be associated with progressive emphysema

Clinical Science

Volumn 130, Issue 4, 2016, Pages 273-287

  Conlon, Thomas M ^a   Bartel, Jörg ^a   Ballweg, Korbinian ^a   Göunter, Stefanie ^a   Prehn, Cornelia ^b   Krumsiek, Jan ^a   Meiners, Silke ^a   Theis, Fabian J ^a   Adamski, Jerzy ^a,b,c   Eickelberg, Oliver ^a,d   Yildirim, Ali Önder ^a  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

^b Genome Analysis Center   (Germany)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^d LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

Biomarkers; Chronic obstructive pulmonary disease (COPD); Metabolome; Ppoptosis

Indexed keywords

ACYLCARNITINE; AMINO ACID; BIOGENIC AMINE; CARNITINE; LYSOPHOSPHATIDYLCHOLINE; PANCREATIC ELASTASE; BIOLOGICAL MARKER; SUPEROXIDE;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRONCHOALVEOLAR LAVAGE FLUID; CELL STIMULATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; DISEASE COURSE; FEMALE; IN VITRO STUDY; IN VIVO STUDY; LEUKOCYTE DIFFERENTIAL COUNT; LUNG; LUNG ALVEOLUS CELL; LUNG COMPLIANCE; LUNG EMPHYSEMA; LUNG FUNCTION; METABOLOME; METABOLOMICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; TOTAL LUNG CAPACITY; ANIMAL; BLOOD; C57BL MOUSE; CELL LINE; CHEMICALLY INDUCED; CHEMISTRY; DISEASE MODEL; DOWN REGULATION; DRUG EFFECTS; EPITHELIUM CELL; MASS SPECTROMETRY; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PROCEDURES; PULMONARY EMPHYSEMA; REGRESSION ANALYSIS; TIME FACTOR;

ANIMALS; APOPTOSIS; BIOMARKERS; BRONCHOALVEOLAR LAVAGE FLUID; CARNITINE; CELL LINE; DISEASE MODELS, ANIMAL; DOWN-REGULATION; EPITHELIAL CELLS; FEMALE; LEAST-SQUARES ANALYSIS; LUNG; LUNG COMPLIANCE; MASS SPECTROMETRY; METABOLOME; METABOLOMICS; MICE, INBRED C57BL; PANCREATIC ELASTASE; PULMONARY EMPHYSEMA; SUPEROXIDES; TIME FACTORS;

EID: 84958045017     PISSN: 01435221     EISSN: 14708736     Source Type: Journal    
DOI: 10.1042/CS20150438     Document Type: Article

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