Coactivator-associated arginine methyltransferase-1 function in alveolar epithelial senescence and elastase-induced emphysema susceptibility

American Journal of Respiratory Cell and Molecular Biology

Volumn 53, Issue 6, 2015, Pages 769-781

  Sarker, Rim S J ^a   John Schuster, Gerrit ^a   Bohla, Alexander ^a   Mutze, Kathrin ^a   Burgstaller, Gerald ^a   Bedford, Mark T ^b   Nigshoff, Melanie Kö ^a   Eickelberg, Oliver ^a,c   Yildirim, Ali O ^a  

^a Center for Lung Research   (Germany)

^b UNIVERSITY OF TEXAS   (United States)

^c LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

Alveolar type II cells; Coactivator associated arginine methyltransferase 1; Elastase treatment; Emphysema; Lung regeneration; Senescence

Indexed keywords

BETA GALACTOSIDASE; COACTIVATOR ASSOCIATED ARGININE METHYLTRANSFERASE 1; MESSENGER RNA; PANCREATIC ELASTASE; PROTEIN ARGININE METHYLTRANSFERASE; PROTEIN P16; PROTEIN P21; SIRTUIN 1; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; COACTIVATOR-ASSOCIATED ARGININE METHYLTRANSFERASE 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL AGING; CELL DIFFERENTIATION; CELL MATURATION; CELL MIGRATION; CELL TRANSDIFFERENTIATION; CONTROLLED STUDY; DISEASE COURSE; DISEASE PREDISPOSITION; DOWN REGULATION; ELASTASE-INDUCED EMPHYSEMA; FEMALE; FUNCTIONAL RESIDUAL CAPACITY; HAPLOINSUFFICIENCY; HETEROZYGOSITY; IN VITRO STUDY; IN VIVO STUDY; LUNG ALVEOLUS EPITHELIUM CELL; LUNG COMPLIANCE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN METHYLATION; PROTEIN PHOSPHORYLATION; SENESCENCE; TISSUE REGENERATION; WOUND HEALING IMPAIRMENT; ANIMAL; C57BL MOUSE; CELL LINE; CHEMICALLY INDUCED; ENZYMOLOGY; GENETIC PREDISPOSITION; LUNG EMPHYSEMA; PHYSIOLOGY;

ALVEOLAR EPITHELIAL CELLS; ANIMALS; CELL AGING; CELL DIFFERENTIATION; CELL LINE; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HAPLOINSUFFICIENCY; MICE, INBRED C57BL; PANCREATIC ELASTASE; PROTEIN-ARGININE N-METHYLTRANSFERASES; PULMONARY EMPHYSEMA;

EID: 84963807849     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2014-0216OC     Document Type: Article

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