Identification of the glycosaminoglycan binding site of interleukin-10 by NMR spectroscopy

Journal of Biological Chemistry

Volumn 291, Issue 6, 2016, Pages 3100-3113

  Kunze, Georg ^a   Köhling, Sebastian ^a,b   Vogel, Alexander ^a   Rademann, Jörg ^a,b   Huster, Daniel ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BINS; CHEMICAL SHIFT; COMPLEXATION; CRYSTAL STRUCTURE; LIGANDS; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POLYSACCHARIDES; PROTEINS;

BIOLOGICAL SIGNIFICANCE; CHEMICAL SHIFT PERTURBATIONS; EXPERIMENTAL CHARACTERIZATION; EXPERIMENTAL DETERMINATION; EXTRACELLULAR MATRICES; MOLECULAR DYNAMICS SIMULATIONS; PROTEIN-LIGAND COMPLEXES; STRUCTURAL CHARACTERIZATION;

BINDING SITES;

ARGININE; GLYCOSAMINOGLYCAN; HEPARIN; INTERLEUKIN 10; LANTHANIDE; LYSINE; GLUCOSAMINOGLYCANS; IL10 PROTEIN, MOUSE;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; HUMAN; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN STRUCTURE; ANIMAL; CHEMISTRY; GENETICS; METABOLISM; MOUSE; NUCLEAR MAGNETIC RESONANCE; X RAY CRYSTALLOGRAPHY;

ANIMALS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; GLYCOSAMINOGLYCANS; INTERLEUKIN-10; MICE; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR;

EID: 84958012411     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.681759     Document Type: Article

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