-
1
-
-
84888143300
-
Loss of dE2F compromises mitochondrial function
-
Ambrus A.M., Islam A.B., Holmes K.B., Moon N.S., Lopez-Bigas N., Benevolenskaya E.V., Frolov M.V. Loss of dE2F compromises mitochondrial function. Dev. Cell 2013, 27:438-451.
-
(2013)
Dev. Cell
, vol.27
, pp. 438-451
-
-
Ambrus, A.M.1
Islam, A.B.2
Holmes, K.B.3
Moon, N.S.4
Lopez-Bigas, N.5
Benevolenskaya, E.V.6
Frolov, M.V.7
-
2
-
-
84959852003
-
The history and future of targeting cyclin-dependent kinases in cancer therapy
-
Asghar U., Witkiewicz A.K., Turner N.C., Knudsen E.S. The history and future of targeting cyclin-dependent kinases in cancer therapy. Nat. Rev. Drug Discov. 2015, 14:130-146.
-
(2015)
Nat. Rev. Drug Discov.
, vol.14
, pp. 130-146
-
-
Asghar, U.1
Witkiewicz, A.K.2
Turner, N.C.3
Knudsen, E.S.4
-
3
-
-
84919863195
-
MCT4 defines a glycolytic subtype of pancreatic cancer with poor prognosis and unique metabolic dependencies
-
Baek G., Tse Y.F., Hu Z., Cox D., Buboltz N., McCue P., Yeo C.J., White M.A., DeBerardinis R.J., Knudsen E.S., Witkiewicz A.K. MCT4 defines a glycolytic subtype of pancreatic cancer with poor prognosis and unique metabolic dependencies. Cell Rep. 2014, 9:2233-2249.
-
(2014)
Cell Rep.
, vol.9
, pp. 2233-2249
-
-
Baek, G.1
Tse, Y.F.2
Hu, Z.3
Cox, D.4
Buboltz, N.5
McCue, P.6
Yeo, C.J.7
White, M.A.8
DeBerardinis, R.J.9
Knudsen, E.S.10
Witkiewicz, A.K.11
-
4
-
-
84923188503
-
Emerging links between E2F control and mitochondrial function
-
Benevolenskaya E.V., Frolov M.V. Emerging links between E2F control and mitochondrial function. Cancer Res. 2015, 75:619-623.
-
(2015)
Cancer Res.
, vol.75
, pp. 619-623
-
-
Benevolenskaya, E.V.1
Frolov, M.V.2
-
5
-
-
80052507407
-
E2F transcription factor-regulates oxidative metabolism
-
Blanchet E., Annicotte J.S., Lagarrigue S., Aguilar V., Clapé C., Chavey C., Fritz V., Casas F., Apparailly F., Auwerx J., Fajas L. E2F transcription factor-regulates oxidative metabolism. Nat. Cell Biol. 2011, 13:1146-1152.
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 1146-1152
-
-
Blanchet, E.1
Annicotte, J.S.2
Lagarrigue, S.3
Aguilar, V.4
Clapé, C.5
Chavey, C.6
Fritz, V.7
Casas, F.8
Apparailly, F.9
Auwerx, J.10
Fajas, L.11
-
6
-
-
33846924500
-
Loss of Mcl-protein and inhibition of electron transport chain together induce anoxic cell death
-
Brunelle J.K., Shroff E.H., Perlman H., Strasser A., Moraes C.T., Flavell R.A., Danial N.N., Keith B., Thompson C.B., Chandel N.S. Loss of Mcl-protein and inhibition of electron transport chain together induce anoxic cell death. Mol. Cell. Biol. 2007, 27:1222-1235.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 1222-1235
-
-
Brunelle, J.K.1
Shroff, E.H.2
Perlman, H.3
Strasser, A.4
Moraes, C.T.5
Flavell, R.A.6
Danial, N.N.7
Keith, B.8
Thompson, C.B.9
Chandel, N.S.10
-
7
-
-
84892861646
-
KRAS: feeding pancreatic cancer proliferation
-
Bryant K.L., Mancias J.D., Kimmelman A.C., Der C.J. KRAS: feeding pancreatic cancer proliferation. Trends Biochem. Sci. 2014, 39:91-100.
-
(2014)
Trends Biochem. Sci.
, vol.39
, pp. 91-100
-
-
Bryant, K.L.1
Mancias, J.D.2
Kimmelman, A.C.3
Der, C.J.4
-
8
-
-
84870169302
-
Driving the cell cycle through metabolism
-
Cai L., Tu B.P. Driving the cell cycle through metabolism. Annu. Rev. Cell Dev. Biol. 2012, 28:59-87.
-
(2012)
Annu. Rev. Cell Dev. Biol.
, vol.28
, pp. 59-87
-
-
Cai, L.1
Tu, B.P.2
-
9
-
-
77950486542
-
Dissecting the unique role of the retinoblastoma tumor suppressor during cellular senescence
-
Chicas A., Wang X., Zhang C., McCurrach M., Zhao Z., Mert O., Dickins R.A., Narita M., Zhang M., Lowe S.W. Dissecting the unique role of the retinoblastoma tumor suppressor during cellular senescence. Cancer Cell 2010, 17:376-387.
-
(2010)
Cancer Cell
, vol.17
, pp. 376-387
-
-
Chicas, A.1
Wang, X.2
Zhang, C.3
McCurrach, M.4
Zhao, Z.5
Mert, O.6
Dickins, R.A.7
Narita, M.8
Zhang, M.9
Lowe, S.W.10
-
10
-
-
84869228046
-
Molecular pathways: regulation of metabolism by RB
-
Clem B.F., Chesney J. Molecular pathways: regulation of metabolism by RB. Clin. Cancer Res. 2012, 18:6096-6100.
-
(2012)
Clin. Cancer Res.
, vol.18
, pp. 6096-6100
-
-
Clem, B.F.1
Chesney, J.2
-
11
-
-
0034283029
-
The Drosophila cyclin D-Cdk4 complex promotes cellular growth
-
Datar S.A., Jacobs H.W., de la Cruz A.F., Lehner C.F., Edgar B.A. The Drosophila cyclin D-Cdk4 complex promotes cellular growth. EMBO J. 2000, 19:4543-4554.
-
(2000)
EMBO J.
, vol.19
, pp. 4543-4554
-
-
Datar, S.A.1
Jacobs, H.W.2
de la Cruz, A.F.3
Lehner, C.F.4
Edgar, B.A.5
-
12
-
-
77954757207
-
Therapeutic CDK4/6 inhibition in breast cancer: key mechanisms of response and failure
-
Dean J.L., Thangavel C., McClendon A.K., Reed C.A., Knudsen E.S. Therapeutic CDK4/6 inhibition in breast cancer: key mechanisms of response and failure. Oncogene 2010, 29:4018-4032.
-
(2010)
Oncogene
, vol.29
, pp. 4018-4032
-
-
Dean, J.L.1
Thangavel, C.2
McClendon, A.K.3
Reed, C.A.4
Knudsen, E.S.5
-
13
-
-
84903843882
-
Molecular pathways: CDK4 inhibitors for cancer therapy
-
Dickson M.A. Molecular pathways: CDK4 inhibitors for cancer therapy. Clin. Cancer Res. 2014, 20:3379-3383.
-
(2014)
Clin. Cancer Res.
, vol.20
, pp. 3379-3383
-
-
Dickson, M.A.1
-
14
-
-
84906238717
-
CDK4/6 inhibitors have potent activity in combination with pathway selective therapeutic agents in models of pancreatic cancer
-
Franco J., Witkiewicz A.K., Knudsen E.S. CDK4/6 inhibitors have potent activity in combination with pathway selective therapeutic agents in models of pancreatic cancer. Oncotarget 2014, 5:6512-6525.
-
(2014)
Oncotarget
, vol.5
, pp. 6512-6525
-
-
Franco, J.1
Witkiewicz, A.K.2
Knudsen, E.S.3
-
15
-
-
9444228344
-
Specific inhibition of cyclin-dependent kinase 4/6 by PD 0332991 and associated antitumor activity in human tumor xenografts
-
Fry D.W., Harvey P.J., Keller P.R., Elliott W.L., Meade M., Trachet E., Albassam M., Zheng X., Leopold W.R., Pryer N.K., Toogood P.L. Specific inhibition of cyclin-dependent kinase 4/6 by PD 0332991 and associated antitumor activity in human tumor xenografts. Mol. Cancer Ther. 2004, 3:1427-1438.
-
(2004)
Mol. Cancer Ther.
, vol.3
, pp. 1427-1438
-
-
Fry, D.W.1
Harvey, P.J.2
Keller, P.R.3
Elliott, W.L.4
Meade, M.5
Trachet, E.6
Albassam, M.7
Zheng, X.8
Leopold, W.R.9
Pryer, N.K.10
Toogood, P.L.11
-
16
-
-
84887045362
-
Metabolic targets for cancer therapy
-
Galluzzi L., Kepp O., Vander Heiden M.G., Kroemer G. Metabolic targets for cancer therapy. Nat. Rev. Drug Discov. 2013, 12:829-846.
-
(2013)
Nat. Rev. Drug Discov.
, vol.12
, pp. 829-846
-
-
Galluzzi, L.1
Kepp, O.2
Vander Heiden, M.G.3
Kroemer, G.4
-
17
-
-
84889575198
-
Modulation of oxidative stress as an anticancer strategy
-
Gorrini C., Harris I.S., Mak T.W. Modulation of oxidative stress as an anticancer strategy. Nat. Rev. Drug Discov. 2013, 12:931-947.
-
(2013)
Nat. Rev. Drug Discov.
, vol.12
, pp. 931-947
-
-
Gorrini, C.1
Harris, I.S.2
Mak, T.W.3
-
18
-
-
84904247308
-
CDK4/6 and IGF1 receptor inhibitors synergize to suppress the growth of p16INK4A-deficient pancreatic cancers
-
Heilmann A.M., Perera R.M., Ecker V., Nicolay B.N., Bardeesy N., Benes C.H., Dyson N.J. CDK4/6 and IGF1 receptor inhibitors synergize to suppress the growth of p16INK4A-deficient pancreatic cancers. Cancer Res. 2014, 74:3947-3958.
-
(2014)
Cancer Res.
, vol.74
, pp. 3947-3958
-
-
Heilmann, A.M.1
Perera, R.M.2
Ecker, V.3
Nicolay, B.N.4
Bardeesy, N.5
Benes, C.H.6
Dyson, N.J.7
-
19
-
-
84877246101
-
The retinoblastoma protein induces apoptosis directly at the mitochondria
-
Hilgendorf K.I., Leshchiner E.S., Nedelcu S., Maynard M.A., Calo E., Ianari A., Walensky L.D., Lees J.A. The retinoblastoma protein induces apoptosis directly at the mitochondria. Genes Dev. 2013, 27:1003-1015.
-
(2013)
Genes Dev.
, vol.27
, pp. 1003-1015
-
-
Hilgendorf, K.I.1
Leshchiner, E.S.2
Nedelcu, S.3
Maynard, M.A.4
Calo, E.5
Ianari, A.6
Walensky, L.D.7
Lees, J.A.8
-
20
-
-
0030849455
-
Dual mechanisms for the inhibition of E2F binding to RB by cyclin-dependent kinase-mediated RB phosphorylation
-
Knudsen E.S., Wang J.Y. Dual mechanisms for the inhibition of E2F binding to RB by cyclin-dependent kinase-mediated RB phosphorylation. Mol. Cell. Biol. 1997, 17:5771-5783.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 5771-5783
-
-
Knudsen, E.S.1
Wang, J.Y.2
-
21
-
-
0042354669
-
A mechanism of cyclin D1 action encoded in the patterns of gene expression in human cancer
-
Lamb J., Ramaswamy S., Ford H.L., Contreras B., Martinez R.V., Kittrell F.S., Zahnow C.A., Patterson N., Golub T.R., Ewen M.E. A mechanism of cyclin D1 action encoded in the patterns of gene expression in human cancer. Cell 2003, 114:323-334.
-
(2003)
Cell
, vol.114
, pp. 323-334
-
-
Lamb, J.1
Ramaswamy, S.2
Ford, H.L.3
Contreras, B.4
Martinez, R.V.5
Kittrell, F.S.6
Zahnow, C.A.7
Patterson, N.8
Golub, T.R.9
Ewen, M.E.10
-
22
-
-
84896722414
-
The molecular balancing act of p16(INK4a) in cancer and aging
-
LaPak K.M., Burd C.E. The molecular balancing act of p16(INK4a) in cancer and aging. Mol. Cancer Res. 2014, 12:167-183.
-
(2014)
Mol. Cancer Res.
, vol.12
, pp. 167-183
-
-
LaPak, K.M.1
Burd, C.E.2
-
23
-
-
70350418625
-
MTOR signaling at a glance
-
Laplante M., Sabatini D.M. mTOR signaling at a glance. J. Cell Sci. 2009, 122:3589-3594.
-
(2009)
J. Cell Sci.
, vol.122
, pp. 3589-3594
-
-
Laplante, M.1
Sabatini, D.M.2
-
25
-
-
84861210266
-
Selective CDK4/6 inhibition with tumor responses by PD0332991 in patients with mantle cell lymphoma
-
Leonard J.P., LaCasce A.S., Smith M.R., Noy A., Chirieac L.R., Rodig S.J., Yu J.Q., Vallabhajosula S., Schoder H., English P., et al. Selective CDK4/6 inhibition with tumor responses by PD0332991 in patients with mantle cell lymphoma. Blood 2012, 119:4597-4607.
-
(2012)
Blood
, vol.119
, pp. 4597-4607
-
-
Leonard, J.P.1
LaCasce, A.S.2
Smith, M.R.3
Noy, A.4
Chirieac, L.R.5
Rodig, S.J.6
Yu, J.Q.7
Vallabhajosula, S.8
Schoder, H.9
English, P.10
-
26
-
-
84867415569
-
Cdk4/6 inhibition induces epithelial-mesenchymal transition and enhances invasiveness in pancreatic cancer cells
-
Liu F., Korc M. Cdk4/6 inhibition induces epithelial-mesenchymal transition and enhances invasiveness in pancreatic cancer cells. Mol. Cancer Ther. 2012, 11:2138-2148.
-
(2012)
Mol. Cancer Ther.
, vol.11
, pp. 2138-2148
-
-
Liu, F.1
Korc, M.2
-
27
-
-
84909619139
-
Cell cycle regulation of mitochondrial function
-
Lopez-Mejia I.C., Fajas L. Cell cycle regulation of mitochondrial function. Curr. Opin. Cell Biol. 2015, 33:19-25.
-
(2015)
Curr. Opin. Cell Biol.
, vol.33
, pp. 19-25
-
-
Lopez-Mejia, I.C.1
Fajas, L.2
-
28
-
-
84879766148
-
Pancreatic cancers rely on a novel glutamine metabolism pathway to maintain redox balance
-
Lyssiotis C.A., Son J., Cantley L.C., Kimmelman A.C. Pancreatic cancers rely on a novel glutamine metabolism pathway to maintain redox balance. Cell Cycle 2013, 12:1987-1988.
-
(2013)
Cell Cycle
, vol.12
, pp. 1987-1988
-
-
Lyssiotis, C.A.1
Son, J.2
Cantley, L.C.3
Kimmelman, A.C.4
-
30
-
-
84873039208
-
Loss of RBF1 changes glutamine catabolism
-
Nicolay B.N., Gameiro P.A., Tschöp K., Korenjak M., Heilmann A.M., Asara J.M., Stephanopoulos G., Iliopoulos O., Dyson N.J. Loss of RBF1 changes glutamine catabolism. Genes Dev. 2013, 27:182-196.
-
(2013)
Genes Dev.
, vol.27
, pp. 182-196
-
-
Nicolay, B.N.1
Gameiro, P.A.2
Tschöp, K.3
Korenjak, M.4
Heilmann, A.M.5
Asara, J.M.6
Stephanopoulos, G.7
Iliopoulos, O.8
Dyson, N.J.9
-
31
-
-
84940843287
-
Proteomic analysis of pRb loss highlights a signature of decreased mitochondrial oxidative phosphorylation
-
Nicolay B.N., Danielian P.S., Kottakis F., Lapek J.D., Sanidas I., Miles W.O., Dehnad M., Tschöp K., Gierut J.J., Manning A.L., et al. Proteomic analysis of pRb loss highlights a signature of decreased mitochondrial oxidative phosphorylation. Genes Dev. 2015, 29:1875-1889.
-
(2015)
Genes Dev.
, vol.29
, pp. 1875-1889
-
-
Nicolay, B.N.1
Danielian, P.S.2
Kottakis, F.3
Lapek, J.D.4
Sanidas, I.5
Miles, W.O.6
Dehnad, M.7
Tschöp, K.8
Gierut, J.J.9
Manning, A.L.10
-
32
-
-
20444486559
-
An inhibitor of Bcl-family proteins induces regression of solid tumours
-
Oltersdorf T., Elmore S.W., Shoemaker A.R., Armstrong R.C., Augeri D.J., Belli B.A., Bruncko M., Deckwerth T.L., Dinges J., Hajduk P.J., et al. An inhibitor of Bcl-family proteins induces regression of solid tumours. Nature 2005, 435:677-681.
-
(2005)
Nature
, vol.435
, pp. 677-681
-
-
Oltersdorf, T.1
Elmore, S.W.2
Shoemaker, A.R.3
Armstrong, R.C.4
Augeri, D.J.5
Belli, B.A.6
Bruncko, M.7
Deckwerth, T.L.8
Dinges, J.9
Hajduk, P.J.10
-
33
-
-
84876805063
-
Therapeutic advances in pancreatic cancer
-
Paulson A.S., Tran Cao H.S., Tempero M.A., Lowy A.M. Therapeutic advances in pancreatic cancer. Gastroenterology 2013, 144:1316-1326.
-
(2013)
Gastroenterology
, vol.144
, pp. 1316-1326
-
-
Paulson, A.S.1
Tran Cao, H.S.2
Tempero, M.A.3
Lowy, A.M.4
-
34
-
-
84895071580
-
Control of glutamine metabolism by the tumor suppressor Rb
-
Reynolds M.R., Lane A.N., Robertson B., Kemp S., Liu Y., Hill B.G., Dean D.C., Clem B.F. Control of glutamine metabolism by the tumor suppressor Rb. Oncogene 2014, 33:556-566.
-
(2014)
Oncogene
, vol.33
, pp. 556-566
-
-
Reynolds, M.R.1
Lane, A.N.2
Robertson, B.3
Kemp, S.4
Liu, Y.5
Hill, B.G.6
Dean, D.C.7
Clem, B.F.8
-
35
-
-
84859079523
-
Multiple roles of cyclin-dependent kinase 4/6 inhibitors in cancer therapy
-
Roberts P.J., Bisi J.E., Strum J.C., Combest A.J., Darr D.B., Usary J.E., Zamboni W.C., Wong K.K., Perou C.M., Sharpless N.E. Multiple roles of cyclin-dependent kinase 4/6 inhibitors in cancer therapy. J. Natl. Cancer Inst. 2012, 104:476-487.
-
(2012)
J. Natl. Cancer Inst.
, vol.104
, pp. 476-487
-
-
Roberts, P.J.1
Bisi, J.E.2
Strum, J.C.3
Combest, A.J.4
Darr, D.B.5
Usary, J.E.6
Zamboni, W.C.7
Wong, K.K.8
Perou, C.M.9
Sharpless, N.E.10
-
36
-
-
84908213474
-
Mitochondrial ROS in cancer: initiators, amplifiers or an Achilles' heel?
-
Sabharwal S.S., Schumacker P.T. Mitochondrial ROS in cancer: initiators, amplifiers or an Achilles' heel?. Nat. Rev. Cancer 2014, 14:709-721.
-
(2014)
Nat. Rev. Cancer
, vol.14
, pp. 709-721
-
-
Sabharwal, S.S.1
Schumacker, P.T.2
-
37
-
-
84875047028
-
Advancements in the management of pancreatic cancer: 2013
-
Saif M.W. Advancements in the management of pancreatic cancer: 2013. JOP 2013, 14:112-118.
-
(2013)
JOP
, vol.14
, pp. 112-118
-
-
Saif, M.W.1
-
38
-
-
45849105156
-
The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1
-
Sancak Y., Peterson T.R., Shaul Y.D., Lindquist R.A., Thoreen C.C., Bar-Peled L., Sabatini D.M. The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science 2008, 320:1496-1501.
-
(2008)
Science
, vol.320
, pp. 1496-1501
-
-
Sancak, Y.1
Peterson, T.R.2
Shaul, Y.D.3
Lindquist, R.A.4
Thoreen, C.C.5
Bar-Peled, L.6
Sabatini, D.M.7
-
39
-
-
0028931152
-
Inhibition of ras-induced proliferation and cellular transformation by p16INK4
-
Serrano M., Gómez-Lahoz E., DePinho R.A., Beach D., Bar-Sagi D. Inhibition of ras-induced proliferation and cellular transformation by p16INK4. Science 1995, 267:249-252.
-
(1995)
Science
, vol.267
, pp. 249-252
-
-
Serrano, M.1
Gómez-Lahoz, E.2
DePinho, R.A.3
Beach, D.4
Bar-Sagi, D.5
-
40
-
-
0030944985
-
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
-
Serrano M., Lin A.W., McCurrach M.E., Beach D., Lowe S.W. Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell 1997, 88:593-602.
-
(1997)
Cell
, vol.88
, pp. 593-602
-
-
Serrano, M.1
Lin, A.W.2
McCurrach, M.E.3
Beach, D.4
Lowe, S.W.5
-
41
-
-
84903960967
-
The complex landscape of pancreatic cancer metabolism
-
Sousa C.M., Kimmelman A.C. The complex landscape of pancreatic cancer metabolism. Carcinogenesis 2014, 35:1441-1450.
-
(2014)
Carcinogenesis
, vol.35
, pp. 1441-1450
-
-
Sousa, C.M.1
Kimmelman, A.C.2
-
42
-
-
77954175674
-
Mcl-1; the molecular regulation of protein function
-
Thomas L.W., Lam C., Edwards S.W. Mcl-1; the molecular regulation of protein function. FEBS Lett. 2010, 584:2981-2989.
-
(2010)
FEBS Lett.
, vol.584
, pp. 2981-2989
-
-
Thomas, L.W.1
Lam, C.2
Edwards, S.W.3
-
43
-
-
33750456480
-
Reverse phase protein array: validation of a novel proteomic technology and utility for analysis of primary leukemia specimens and hematopoietic stem cells
-
Tibes R., Qiu Y., Lu Y., Hennessy B., Andreeff M., Mills G.B., Kornblau S.M. Reverse phase protein array: validation of a novel proteomic technology and utility for analysis of primary leukemia specimens and hematopoietic stem cells. Mol. Cancer Ther. 2006, 5:2512-2521.
-
(2006)
Mol. Cancer Ther.
, vol.5
, pp. 2512-2521
-
-
Tibes, R.1
Qiu, Y.2
Lu, Y.3
Hennessy, B.4
Andreeff, M.5
Mills, G.B.6
Kornblau, S.M.7
-
44
-
-
80052242132
-
Targeting cancer metabolism: a therapeutic window opens
-
Vander Heiden M.G. Targeting cancer metabolism: a therapeutic window opens. Nat. Rev. Drug Discov. 2011, 10:671-684.
-
(2011)
Nat. Rev. Drug Discov.
, vol.10
, pp. 671-684
-
-
Vander Heiden, M.G.1
-
45
-
-
84940839674
-
Increased mitochondrial function downstream from KDM5A histone demethylase rescues differentiation in pRB-deficient cells
-
Váraljai R., Islam A.B., Beshiri M.L., Rehman J., Lopez-Bigas N., Benevolenskaya E.V. Increased mitochondrial function downstream from KDM5A histone demethylase rescues differentiation in pRB-deficient cells. Genes Dev. 2015, 29:1817-1834.
-
(2015)
Genes Dev.
, vol.29
, pp. 1817-1834
-
-
Váraljai, R.1
Islam, A.B.2
Beshiri, M.L.3
Rehman, J.4
Lopez-Bigas, N.5
Benevolenskaya, E.V.6
-
46
-
-
84911861458
-
Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function
-
Viale A., Pettazzoni P., Lyssiotis C.A., Ying H., Sánchez N., Marchesini M., Carugo A., Green T., Seth S., Giuliani V., et al. Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function. Nature 2014, 514:628-632.
-
(2014)
Nature
, vol.514
, pp. 628-632
-
-
Viale, A.1
Pettazzoni, P.2
Lyssiotis, C.A.3
Ying, H.4
Sánchez, N.5
Marchesini, M.6
Carugo, A.7
Green, T.8
Seth, S.9
Giuliani, V.10
-
47
-
-
80051700067
-
Pancreatic cancer
-
Vincent A., Herman J., Schulick R., Hruban R.H., Goggins M. Pancreatic cancer. Lancet 2011, 378:607-620.
-
(2011)
Lancet
, vol.378
, pp. 607-620
-
-
Vincent, A.1
Herman, J.2
Schulick, R.3
Hruban, R.H.4
Goggins, M.5
-
48
-
-
84904259645
-
CDK 4/6 inhibitors sensitize PIK3CA mutant breast cancer to PI3K inhibitors
-
Vora S.R., Juric D., Kim N., Mino-Kenudson M., Huynh T., Costa C., Lockerman E.L., Pollack S.F., Liu M., Li X., et al. CDK 4/6 inhibitors sensitize PIK3CA mutant breast cancer to PI3K inhibitors. Cancer Cell 2014, 26:136-149.
-
(2014)
Cancer Cell
, vol.26
, pp. 136-149
-
-
Vora, S.R.1
Juric, D.2
Kim, N.3
Mino-Kenudson, M.4
Huynh, T.5
Costa, C.6
Lockerman, E.L.7
Pollack, S.F.8
Liu, M.9
Li, X.10
-
49
-
-
33746814985
-
Cyclin D1 repression of nuclear respiratory factor 1 integrates nuclear DNA synthesis and mitochondrial function
-
Wang C., Li Z., Lu Y., Du R., Katiyar S., Yang J., Fu M., Leader J.E., Quong A., Novikoff P.M., Pestell R.G. Cyclin D1 repression of nuclear respiratory factor 1 integrates nuclear DNA synthesis and mitochondrial function. Proc. Natl. Acad. Sci. USA 2006, 103:11567-11572.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 11567-11572
-
-
Wang, C.1
Li, Z.2
Lu, Y.3
Du, R.4
Katiyar, S.5
Yang, J.6
Fu, M.7
Leader, J.E.8
Quong, A.9
Novikoff, P.M.10
Pestell, R.G.11
-
50
-
-
79961117100
-
The meaning of p16(ink4a) expression in tumors: functional significance, clinical associations and future developments
-
Witkiewicz A.K., Knudsen K.E., Dicker A.P., Knudsen E.S. The meaning of p16(ink4a) expression in tumors: functional significance, clinical associations and future developments. Cell Cycle 2011, 10:2497-2503.
-
(2011)
Cell Cycle
, vol.10
, pp. 2497-2503
-
-
Witkiewicz, A.K.1
Knudsen, K.E.2
Dicker, A.P.3
Knudsen, E.S.4
-
51
-
-
84937851216
-
Selective impact of CDK4/6 suppression on patient-derived models of pancreatic cancer
-
Witkiewicz A.K., Borja N.A., Franco J., Brody J.R., Yeo C.J., Mansour J., Choti M.A., McCue P., Knudsen E.S. Selective impact of CDK4/6 suppression on patient-derived models of pancreatic cancer. Oncotarget 2015, 6:15788-15801.
-
(2015)
Oncotarget
, vol.6
, pp. 15788-15801
-
-
Witkiewicz, A.K.1
Borja, N.A.2
Franco, J.3
Brody, J.R.4
Yeo, C.J.5
Mansour, J.6
Choti, M.A.7
McCue, P.8
Knudsen, E.S.9
-
52
-
-
84927144113
-
Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets
-
Witkiewicz A.K., McMillan E.A., Balaji U., Baek G., Lin W.C., Mansour J., Mollaee M., Wagner K.U., Koduru P., Yopp A., et al. Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets. Nat. Commun. 2015, 6:6744.
-
(2015)
Nat. Commun.
, vol.6
, pp. 6744
-
-
Witkiewicz, A.K.1
McMillan, E.A.2
Balaji, U.3
Baek, G.4
Lin, W.C.5
Mansour, J.6
Mollaee, M.7
Wagner, K.U.8
Koduru, P.9
Yopp, A.10
-
53
-
-
84860321700
-
Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism
-
Ying H., Kimmelman A.C., Lyssiotis C.A., Hua S., Chu G.C., Fletcher-Sananikone E., Locasale J.W., Son J., Zhang H., Coloff J.L., et al. Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism. Cell 2012, 149:656-670.
-
(2012)
Cell
, vol.149
, pp. 656-670
-
-
Ying, H.1
Kimmelman, A.C.2
Lyssiotis, C.A.3
Hua, S.4
Chu, G.C.5
Fletcher-Sananikone, E.6
Locasale, J.W.7
Son, J.8
Zhang, H.9
Coloff, J.L.10
|