-
2
-
-
59149105528
-
Improvement of overall survival in advanced stage mantle cell lymphoma
-
Herrmann A, Hoster E, Zwingers T, et al. Improvement of overall survival in advanced stage mantle cell lymphoma. J Clin Oncol. 2009;27(4): 511-518.
-
(2009)
J Clin Oncol
, vol.27
, Issue.4
, pp. 511-518
-
-
Herrmann, A.1
Hoster, E.2
Zwingers, T.3
-
3
-
-
70349748583
-
Frontline therapy in mantle cell lymphoma: The role of high-dose therapy and integration of new agents
-
Kahl BS. Frontline therapy in mantle cell lymphoma: the role of high-dose therapy and integration of new agents. Curr Hematol Malig Rep. 2009;4(4):213-217.
-
(2009)
Curr Hematol Malig Rep
, vol.4
, Issue.4
, pp. 213-217
-
-
Kahl, B.S.1
-
4
-
-
79952164250
-
Should there be a standard therapy for mantle cell lymphoma?
-
Smith MR. Should there be a standard therapy for mantle cell lymphoma? Future Oncol. 2011;7(2): 227-237.
-
(2011)
Future Oncol
, vol.7
, Issue.2
, pp. 227-237
-
-
Smith, M.R.1
-
5
-
-
80053131089
-
Mantle cell lymphoma: The promise of new treatment options
-
Goy A, Kahl B. Mantle cell lymphoma: the promise of new treatment options. Crit Rev Oncol Hematol. 2011;80(1):69-86.
-
(2011)
Crit Rev Oncol Hematol
, vol.80
, Issue.1
, pp. 69-86
-
-
Goy, A.1
Kahl, B.2
-
6
-
-
77449116884
-
Mantle cell lymphoma: Biological insights and treatment advances
-
Leonard JP, Williams ME, Goy A, et al. Mantle cell lymphoma: biological insights and treatment advances. Clin Lymphoma Myeloma. 2009;9(4): 267-277.
-
(2009)
Clin Lymphoma Myeloma
, vol.9
, Issue.4
, pp. 267-277
-
-
Leonard, J.P.1
Williams, M.E.2
Goy, A.3
-
7
-
-
78650985963
-
Mantle cell lymphoma: Biology, pathogenesis, and the molecular basis of treatment in the genomic era
-
Pérez-Galán P, Dreyling M, Wiestner A. Mantle cell lymphoma: biology, pathogenesis, and the molecular basis of treatment in the genomic era. Blood. 2011;117(1):26-38.
-
(2011)
Blood
, vol.117
, Issue.1
, pp. 26-38
-
-
Pérez-Galán, P.1
Dreyling, M.2
Wiestner, A.3
-
8
-
-
0021270716
-
Molecular cloning of the chromosomal breakpoint of B-cell lymphomas and leukemias with the t(11;14) chromosome translocation
-
Tsujimoto Y, Yunis J, Onorato-Showe L, et al. Molecular cloning of the chromosomal breakpoint of B-cell lymphomas and leukemias with the t(11;14) chromosome translocation. Science. 1984; 224(4656):1403-1406. (Pubitemid 14123338)
-
(1984)
Science
, vol.224
, Issue.4656
, pp. 1403-1406
-
-
Tsujimoto, Y.1
Yunis, J.2
Onorato-Showe, L.3
-
9
-
-
0025942999
-
PRAD1, a candidate BCL1 oncogene: Mapping and expression in centrocytic lymphoma
-
Rosenberg CL, Wong E, Petty EM, et al. PRAD1, a candidate BCL1 oncogene: mapping and expression in centrocytic lymphoma. Proc Natl Acad Sci U S A. 1991;88(21):9638-9642. (Pubitemid 21915686)
-
(1991)
Proceedings of the National Academy of Sciences of the United States of America
, vol.88
, Issue.21
, pp. 9638-9642
-
-
Rosenberg, C.L.1
Wong, E.2
Petty, E.M.3
Bale, A.E.4
Tsujimoto, Y.5
Harris, N.L.6
Arnold, A.7
-
10
-
-
0026759027
-
Characterization of chromosome 11 translocation breakpoints at the bcl-1 and PRAD1 loci in centrocytic lymphoma
-
Williams ME, Swerdlow SH, Rosenberg CL, Arnold A. Characterization of chromosome 11 translocation breakpoints at the bcl-1 and PRAD1 loci in centrocytic lymphoma. Cancer Res. 1992; 52(19 suppl):5541s-5544s.
-
(1992)
Cancer Res
, vol.52
, Issue.19 SUPPL.
-
-
Williams, M.E.1
Swerdlow, S.H.2
Rosenberg, C.L.3
Arnold, A.4
-
11
-
-
0028104979
-
PRAD-1/cyclin D1 gene overexpression in chronic lymphoproliferative disorders: A highly specific marker of mantle cell lymphoma
-
Bosch F, Jares P, Campo E, et al. PRAD-1/Cyclin D1 gene overexpression in chronic lymphoproliferative disorders: a highly specific marker of mantle cell lymphoma. Blood. 1994;84(8):2726-2732. (Pubitemid 24317406)
-
(1994)
Blood
, vol.84
, Issue.8
, pp. 2726-2732
-
-
Bosch, F.1
Jares, P.2
Campo, E.3
Lopez-Guillermo, A.4
Piris, M.A.5
Villamor, N.6
Tassies, D.7
Jaffe, E.S.8
Montserrat, E.9
Rozman, C.10
Cardesa, A.11
-
12
-
-
0029002695
-
Cyclin D1 messenger RNA overexpression as a marker for mantle cell lymphoma
-
de Boer CJ, van Krieken JH, Kluin-Nelemans HC, Kluin PM, Schuuring E. Cyclin D1 messenger RNA overexpression as a marker for mantle cell lymphoma. Oncogene. 1995;10(9):1833-1840.
-
(1995)
Oncogene
, vol.10
, Issue.9
, pp. 1833-1840
-
-
De Boer, C.J.1
Van Krieken, J.H.2
Kluin-Nelemans, H.C.3
Kluin, P.M.4
Schuuring, E.5
-
13
-
-
34648824397
-
Genetic and molecular pathogenesis of mantle cell lymphoma: Perspectives for new targeted therapeutics
-
DOI 10.1038/nrc2230, PII NRC2230
-
Jares P, Colomer D, Campo E. Genetic and molecular pathogenesis of mantle cell lymphoma: perspectives for new targeted therapeutics. Nat Rev Cancer. 2007;7(10):750-762. (Pubitemid 47463673)
-
(2007)
Nature Reviews Cancer
, vol.7
, Issue.10
, pp. 750-762
-
-
Jares, P.1
Colomer, D.2
Campo, E.3
-
14
-
-
33645802169
-
Cyclin-dependent kinase pathways as targets for cancer treatment
-
DOI 10.1200/JCO.2005.03.7689
-
Shapiro GI. Cyclin-dependent kinase pathways as targets for cancer treatment. J Clin Oncol. 2006;24(11):1770-1783. (Pubitemid 46628473)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.11
, pp. 1770-1783
-
-
Shapiro, G.I.1
-
15
-
-
33748184149
-
Mantle cell lymphoma cells express predominantly cyclin D1a isoform and are highly sensitive to selective inhibition of CDK4 kinase activity
-
DOI 10.1182/blood-2006-04-016634
-
Marzec M, Kasprzycka M, Lai R, et al. Mantle cell lymphoma cells express predominantly cyclin D1a isoform and are highly sensitive to selective inhibition of CDK4 kinase activity. Blood. 2006; 108(5):1744-1750. (Pubitemid 44316145)
-
(2006)
Blood
, vol.108
, Issue.5
, pp. 1744-1750
-
-
Marzec, M.1
Kasprzycka, M.2
Lai, R.3
Gladden, A.B.4
Wlodarski, P.5
Tomczak, E.6
Nowell, P.7
DePrimo, S.E.8
Sadis, S.9
Eck, S.10
Schuster, S.J.11
Diehl, J.A.12
Wasik, M.A.13
-
16
-
-
0030882326
-
Alterations of the cyclin D1/p16-pRB pathway in mantle cell lymphoma
-
Dreyling MH, Bullinger L, Ott G, et al. Alterations of the cyclin D1/p16-pRB pathway in mantle cell lymphoma. Cancer Res. 1997;57(20):4608-4614. (Pubitemid 27441068)
-
(1997)
Cancer Research
, vol.57
, Issue.20
, pp. 4608-4614
-
-
Dreyling, M.H.1
Bullinger, L.2
Ott, G.3
Stilgenbauer, S.4
Muller-Hermelink, H.K.5
Bentz, M.6
Hiddemann, W.7
Dohner, H.8
-
17
-
-
0013224058
-
The proliferation gene expression signature is a quantitative integrator of oncogenic events that predicts survival in mantle cell lymphoma
-
DOI 10.1016/S1535-6108(03)00028-X
-
Rosenwald A, Wright G, Wiestner A, et al. The proliferation gene expression signature is a quantitative integrator of oncogenic events that predicts survival in mantle cell lymphoma. Cancer Cell. 2003;3(2):185-197. (Pubitemid 37443390)
-
(2003)
Cancer Cell
, vol.3
, Issue.2
, pp. 185-197
-
-
Rosenwald, A.1
Wright, G.2
Wiestner, A.3
Chan, W.C.4
Connors, J.M.5
Campo, E.6
Gascoyne, R.D.7
Grogan, T.M.8
Muller-Hermelink, H.K.9
Smeland, E.B.10
Chiorazzi, M.11
Giltnane, J.M.12
Hurt, E.M.13
Zhao, H.14
Averett, L.15
Henrickson, S.16
Yang, L.17
Powell, J.18
Wilson, W.H.19
Jaffe, E.S.20
Simon, R.21
Klausner, R.D.22
Montserrat, E.23
Bosch, F.24
Greiner, T.C.25
Weisenburger, D.D.26
Sanger, W.G.27
Dave, B.J.28
Lynch, J.C.29
Vose, J.30
Armitage, J.O.31
Fisher, R.I.32
Miller, T.P.33
LeBlanc, M.34
Ott, G.35
Kvaloy, S.36
Holte, H.37
Delabie, J.38
Staudt, L.M.39
more..
-
18
-
-
0035866814
-
BMI-1 gene amplification and overexpression in hematological malignancies occur mainly in mantle cell lymphomas
-
Beà S, Tort F, Pinyol M, et al. BMI-1 gene amplification and overexpression in hematological malignancies occur mainly in mantle cell lymphomas. Cancer Res. 2001;61(6):2409-2412. (Pubitemid 32685815)
-
(2001)
Cancer Research
, vol.61
, Issue.6
, pp. 2409-2412
-
-
Bea, S.1
Tort, F.2
Pinyol, M.3
Puig, X.4
Hernandez, L.5
Hernandez, S.6
Fernandez, P.L.7
Van Lohuizen, M.8
Colomer, D.9
Campo, E.10
-
19
-
-
0038281327
-
Kip1 protein by cyclin D1 in typical and blastic variants of mantle cell lymphoma (MCL): Implications for pathogenesis
-
DOI 10.1182/blood-2002-01-0263
-
Quintanilla-Martinez L, Davies-Hill T, Fend F, et al. Sequestration of p27Kip1 protein by cyclin D1 in typical and blastic variants of mantle cell lymphoma (MCL): implications for pathogenesis. Blood. 2003;101(8):3181-3187. (Pubitemid 36858013)
-
(2003)
Blood
, vol.101
, Issue.8
, pp. 3181-3187
-
-
Quintanilla-Martinez, L.1
Davies-Hill, T.2
Fend, F.3
Calzada-Wack, J.4
Sorbara, L.5
Campo, E.6
Jaffe, E.S.7
Raffeld, M.8
-
20
-
-
0038473927
-
Flavopiridol in untreated or relapsed mantle-cell lymphoma: Results of a phase II study of the National Cancer Institute of Canada Clinical Trials Group
-
DOI 10.1200/jco.2003.09.057
-
Kouroukis CT, Belch A, Crump M, et al. Flavopiridol is untreated or relapsed mantle-cell lymphoma: results of a phase II study of the National Cancer Institute of Canada Clinical Trials Group. J Clin Oncol. 2003;21(9):1740-1745. (Pubitemid 46638586)
-
(2003)
Journal of Clinical Oncology
, vol.21
, Issue.9
, pp. 1740-1745
-
-
Kouroukis, C.T.1
Belch, A.2
Crump, M.3
Eisenhauer, E.4
Gascoyne, R.D.5
Meyer, R.6
Lohmann, R.7
Lopez, P.8
Powers, J.9
Turner, R.10
Connors, J.M.11
-
21
-
-
77249164677
-
Phase I/II study of a hybrid schedule of flavopiridol in relapsed/refractory mantle cell lymphoma (MCL) and diffuse large B-cell lymphoma (DLBCL)
-
abstract
-
Tay K, Shapiro G, Disinski M, et al. Phase I/II study of a hybrid schedule of flavopiridol in relapsed/refractory mantle cell lymphoma (MCL) and diffuse large B-cell lymphoma (DLBCL) [abstract]. Proc Am Soc Clin Oncol. 2009;27: A8563.
-
(2009)
Proc Am Soc Clin Oncol
, vol.27
-
-
Tay, K.1
Shapiro, G.2
Disinski, M.3
-
22
-
-
25444502962
-
In vitro activity of cyclin-dependent kinase inhibitor CYC202 (Seliciclib, R-roscovitine) in mantle cell lymphomas
-
DOI 10.1093/annonc/mdi217
-
Lacrima K, Valentini A, Lambertini C, et al. In vitro activity of cyclin-dependent kinase inhibitor CYC202 (Seliciclib, R-roscovitine) in mantle cell lymphomas. Ann Oncol. 2005;16(7):1169-1176. (Pubitemid 41418321)
-
(2005)
Annals of Oncology
, vol.16
, Issue.7
, pp. 1169-1176
-
-
Lacrima, K.1
Valentini, A.2
Lambertini, C.3
Taborelli, M.4
Rinaldi, A.5
Zucca, E.6
Catapano, C.7
Cavalli, F.8
Gianella-Borradori, A.9
MacCallum, D.E.10
Bertoni, F.11
-
23
-
-
77955720554
-
Responses in mantle cell lymphoma cells to SNS-032 depend on the biological context of each cell line
-
Chen R, Chubb S, Cheng T, et al. Responses in mantle cell lymphoma cells to SNS-032 depend on the biological context of each cell line. Cancer Res. 2010;70(16):6587-6597.
-
(2010)
Cancer Res
, vol.70
, Issue.16
, pp. 6587-6597
-
-
Chen, R.1
Chubb, S.2
Cheng, T.3
-
24
-
-
9444228344
-
Specific inhibition of cyclin-dependent kinase 4/6 by PD 0332991 and associated antitumor activity in human tumor xenografts
-
Fry DW, Harvey PJ, Keller PR, et al. Specific inhibition of cyclin-dependent kinase 4/6 by PD 0332991 and associated antitumor activity in human tumor xenografts. Mol Cancer Ther. 2004; 3(11):1427-1438.
-
(2004)
Mol Cancer Ther
, vol.3
, Issue.11
, pp. 1427-1438
-
-
Fry, D.W.1
Harvey, P.J.2
Keller, P.R.3
-
25
-
-
20244365948
-
Discovery of a potent and selective inhibitor of cyclin-dependent kinase 4/6
-
DOI 10.1021/jm049354h
-
Toogood PL, Harvey PJ, Repine JT, et al. Discovery of a potent and selective inhibitor of cyclindependent kinase 4/6. J Med Chem. 2005;48(7): 2388-2406. (Pubitemid 40516432)
-
(2005)
Journal of Medicinal Chemistry
, vol.48
, Issue.7
, pp. 2388-2406
-
-
Toogood, P.L.1
Harvey, P.J.2
Repine, J.T.3
Sheehan, D.J.4
VanderWel, S.N.5
Zhou, H.6
Keller, P.R.7
McNamara, D.J.8
Sherry, D.9
Zhu, T.10
Brodfuehrer, J.11
Choi, C.12
Barvian, M.R.13
Fry, D.W.14
-
26
-
-
84855983664
-
Phase I, dose-escalation trial of the oral cyclin-dependent kinase 4/6 inhibitor PD0332991, administered using a 21-day schedule in patients with advanced cancer
-
Flaherty KT, LoRusso PM, DeMichele A, et al. Phase I, dose-escalation trial of the oral cyclin-dependent kinase 4/6 inhibitor PD0332991, administered using a 21-day schedule in patients with advanced cancer. Clin Cancer Res. 2012; 18(2):568-576.
-
(2012)
Clin Cancer Res
, vol.18
, Issue.2
, pp. 568-576
-
-
Flaherty, K.T.1
LoRusso, P.M.2
DeMichele, A.3
-
27
-
-
79958149971
-
Phase I study of PD 0332991, a cyclin-dependent kinase inhibitor, administered in 3-week cycles (Schedule 2/1)
-
Schwartz GK, Lorusso PM, Dickson MA, et al. Phase I study of PD 0332991, a cyclin-dependent kinase inhibitor, administered in 3-week cycles (Schedule 2/1). Br J Cancer. 2011;104(12):1862-1868.
-
(2011)
Br J Cancer
, vol.104
, Issue.12
, pp. 1862-1868
-
-
Schwartz, G.K.1
Lorusso, P.M.2
Dickson, M.A.3
-
28
-
-
58749096358
-
Treatment of growing teratoma syndrome
-
Vaughn DJ, Flaherty K, Lal P, et al. Treatment of growing teratoma syndrome. N Engl J Med. 2009; 360(4):423-424.
-
(2009)
N Engl J Med
, vol.360
, Issue.4
, pp. 423-424
-
-
Vaughn, D.J.1
Flaherty, K.2
Lal, P.3
-
29
-
-
46749137956
-
Imaging of cell proliferation: Status and prospects
-
DOI 10.2967/jnumed.107.046391
-
Bading JR, Shields AF. Imaging of cell proliferation: status and prospects. J Nucl Med. 2008; 49(suppl 2):64S-80S. (Pubitemid 351948037)
-
(2008)
Journal of Nuclear Medicine
, vol.49
, Issue.SUPPL.6
-
-
Bading, J.R.1
Shields, A.F.2
-
30
-
-
73649086240
-
Molecular PET and PET/CT imaging of tumour cell proliferation using F-18 fluoro-L-thymidine: A comprehensive evaluation
-
Barwick T, Bencherif B, Mountz JM, Avril N. Molecular PET and PET/CT imaging of tumour cell proliferation using F-18 fluoro-L-thymidine: a comprehensive evaluation. Nucl Med Commun. 2009;30(12):908-917.
-
(2009)
Nucl Med Commun
, vol.30
, Issue.12
, pp. 908-917
-
-
Barwick, T.1
Bencherif, B.2
Mountz, J.M.3
Avril, N.4
-
31
-
-
0042449063
-
Report of an international workshop to standardize response criteria for non-Hodgkin's lymphomas. NCI Sponsored International Working Group
-
Cheson BD, Horning SJ, Coiffier B, et al. Report of an international workshop to standardize response criteria for non-Hodgkin's lymphomas. NCI Sponsored International Working Group. J Clin Oncol. 1999;17(4):1244.
-
(1999)
J Clin Oncol
, vol.17
, Issue.4
, pp. 1244
-
-
Cheson, B.D.1
Horning, S.J.2
Coiffier, B.3
-
32
-
-
0032757213
-
18F]- fluorodeoxyglucose and positron emission tomography: Review and 1999 EORTC recommendations
-
DOI 10.1016/S0959-8049(99)00229-4, PII S0959804999002294
-
Young H, Baum R, Cremerius U, et al. Measurement of clinical and subclinical tumour response using [18F]-fluorodeoxyglucose and positron emission tomography: review and 1999 EORTC recommendations. European Organization for Research and Treatment of Cancer (EORTC) PET Study Group. Eur J Cancer. 1999;35(13): 1773-1782. (Pubitemid 29512308)
-
(1999)
European Journal of Cancer
, vol.35
, Issue.13
, pp. 1773-1782
-
-
Young, H.1
Baum, R.2
Cremerius, U.3
Herholz, K.4
Hoekstra, O.5
Lammertsma, A.A.6
Pruim, J.7
Price, P.8
-
33
-
-
3242712108
-
A phase II clinical and pharmacodynamic study of E7070 in patients with metastatic, recurrent, or refractory squamous cell carcinoma of the head and neck: Modulation of retinoblastoma protein phosphorylation by a novel chloroindolyl sulfonamide cell cycle inhibitor
-
DOI 10.1158/1078-0432.CCR-04-0229
-
Haddad RI, Weinstein LJ, Wieczorek TJ, et al. A phase II clinical and pharmacodynamic study of E7070 in patients with metastatic, recurrent, or refractory squamous cell carcinoma of the head and neck: modulation of retinoblastoma protein phosphorylation by a novel chloroindolyl sulfonamide cell cycle inhibitor. Clin Cancer Res. 2004; 10(14):4680-4687. (Pubitemid 38955518)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.14
, pp. 4680-4687
-
-
Haddad, R.I.1
Weinstein, L.J.2
Wieczorek, T.J.3
Bhattacharya, N.4
Raftopoulos, H.5
Oster, M.W.6
Zhang, X.7
Latham Jr., V.M.8
Costello, R.9
Faucher, J.10
DeRosa, C.11
Yule, M.12
Miller, L.P.13
Loda, M.14
Posner, M.R.15
Shapiro, G.I.16
-
34
-
-
2542477282
-
Consistent immunostaining for cyclin D1 can be achieved on a routine basis using a newly available rabbit monoclonal antibody
-
DOI 10.1097/01.pas.0000126054.95798.94
-
Cheuk W, Wong KO, Wong CS, Chan JK. Consistent immunostaining for cyclin D1 can be achieved on a routine basis using a newly available rabbit monoclonal antibody. Am J Surg Pathol. 2004;28(6):801-807. (Pubitemid 38685895)
-
(2004)
American Journal of Surgical Pathology
, vol.28
, Issue.6
, pp. 801-807
-
-
Cheuk, W.1
Wong, K.O.Y.2
Wong, C.S.C.3
Chan, J.K.C.4
-
35
-
-
0027444652
-
A predictive model for aggressive non-Hodgkin's lymphoma. The International Non-Hodgkin's Lymphoma Prognostic Factors Project
-
A predictive model for aggressive non-Hodgkin's lymphoma. The International Non-Hodgkin's Lymphoma Prognostic Factors Project. N Engl J Med. 1993;329(14):987-994.
-
(1993)
N Engl J Med
, vol.329
, Issue.14
, pp. 987-994
-
-
-
36
-
-
38349104577
-
A new prognostic index (MIPI) for patients with advanced-stage mantle cell lymphoma
-
Hoster E, Dreyling M, Klapper W, et al. A new prognostic index (MIPI) for patients with advanced-stage mantle cell lymphoma. Blood. 2008;111(2):558-565.
-
(2008)
Blood
, vol.111
, Issue.2
, pp. 558-565
-
-
Hoster, E.1
Dreyling, M.2
Klapper, W.3
-
37
-
-
33645729415
-
The Ki67 proliferation index is a quantitative indicator of clinical risk in mantle cell lymphoma
-
Katzenberger T, Petzoldt C, Holler S, et al. The Ki67 proliferation index is a quantitative indicator of clinical risk in mantle cell lymphoma. Blood. 2006;107(8):3407.
-
(2006)
Blood
, vol.107
, Issue.8
, pp. 3407
-
-
Katzenberger, T.1
Petzoldt, C.2
Holler, S.3
-
38
-
-
77950649484
-
Incidence and prognostic impact of secondary cytogenetic aberrations in a series of 145 patients with mantle cell lymphoma
-
Espinet B, Salaverria I, Bea S, et al. Incidence and prognostic impact of secondary cytogenetic aberrations in a series of 145 patients with mantle cell lymphoma. Genes Chromosomes Cancer. 2010;49(5):439-451.
-
(2010)
Genes Chromosomes Cancer
, vol.49
, Issue.5
, pp. 439-451
-
-
Espinet, B.1
Salaverria, I.2
Bea, S.3
-
39
-
-
34548838818
-
Pharmacologic inhibition of CDK4/6: Mechanistic evidence for selective activity or acquired resistance in acute myeloid leukemia
-
DOI 10.1182/blood-2007-02-071266
-
Wang L, Wang J, Blaser BW, et al. Pharmacologic inhibition of CDK4/6: mechanistic evidence for selective activity or acquired resistance in acute myeloid leukemia. Blood. 2007;110(6): 2075-2083. (Pubitemid 47443925)
-
(2007)
Blood
, vol.110
, Issue.6
, pp. 2075-2083
-
-
Wang, L.1
Wang, J.2
Blaser, B.W.3
Duchemin, A.-M.4
Kusewitt, D.F.5
Liu, T.6
Caligiuri, M.A.7
Briesewitz, R.8
-
40
-
-
4444247138
-
Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6
-
DOI 10.1016/j.cell.2004.08.002, PII S0092867404007500
-
Malumbres M, Sotillo R, Santamaria D, et al. Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6. Cell. 2004; 118(4):493-504. (Pubitemid 39485668)
-
(2004)
Cell
, vol.118
, Issue.4
, pp. 493-504
-
-
Malumbres, M.1
Sotillo, R.2
Santamaria, D.3
Galan, J.4
Cerezo, A.5
Ortega, S.6
Dubus, P.7
Barbacid, M.8
-
41
-
-
0033178714
-
Restoration of wild-type p16 down-regulates vascular endothelial growth factor expression and inhibits angiogenesis in human gliomas
-
Harada H, Nakagawa K, Iwata S, et al. Restoration of wild-type p16 down-regulates vascular endothelial growth factor expression and inhibits angiogenesis in human gliomas. Cancer Res. 1999;59(15):3783-3789. (Pubitemid 29381887)
-
(1999)
Cancer Research
, vol.59
, Issue.15
, pp. 3783-3789
-
-
Harada, H.1
Nakagavva, K.2
Iwata, S.3
Saito, M.4
Kumon, Y.5
Sakaki, S.6
Sato, K.7
Hamada, K.8
-
42
-
-
34547684724
-
CDK4 inhibitors and apoptosis: A novel mechanism requiring nucleolar targeting of RelA
-
Thoms HC, Dunlop MG, Stark LA. CDK4 inhibitors and apoptosis: a novel mechanism requiring nucleolar targeting of RelA. Cell Cycle. 2007; 6(11):1293-1297. (Pubitemid 47327959)
-
(2007)
Cell Cycle
, vol.6
, Issue.11
, pp. 1293-1297
-
-
Thoms, H.C.1
Dunlop, M.G.2
Stark, L.A.3
-
43
-
-
83755180834
-
A pilot study to evaluate 3′-deoxy-3′-18F-fluorothymidine PET for initial and early response imaging in mantle cell lymphoma
-
Herrmann K, Buck AK, Schuster T, et al. A pilot study to evaluate 3′-deoxy-3′-18F-fluorothymidine PET for initial and early response imaging in mantle cell lymphoma. J Nucl Med. 2011;52(12):1898-1902.
-
(2011)
J Nucl Med
, vol.52
, Issue.12
, pp. 1898-1902
-
-
Herrmann, K.1
Buck, A.K.2
Schuster, T.3
-
44
-
-
48649105786
-
A novel therapeutic combination using PD 0332991 and bortezomib: Study in the 5T33MM myeloma model
-
Menu E, Garcia J, Huang X, et al. A novel therapeutic combination using PD 0332991 and bortezomib: study in the 5T33MM myeloma model. Cancer Res. 2008;68(14):5519-5523.
-
(2008)
Cancer Res
, vol.68
, Issue.14
, pp. 5519-5523
-
-
Menu, E.1
Garcia, J.2
Huang, X.3
-
45
-
-
33747872306
-
1 arrest in primary myeloma cells and prevents tumor growth by specific inhibition of cyclin-dependent kinase 4/6
-
DOI 10.1158/0008-5472.CAN-06-1098
-
Baughn LB, Di Liberto M, Wu K, et al. A novel orally active small molecule potently induces G1 arrest in primary myeloma cells and prevents tumor growth by specific inhibition of cyclin-dependent kinase 4/6. Cancer Res. 2006;66(15): 7661-7667. (Pubitemid 44289224)
-
(2006)
Cancer Research
, vol.66
, Issue.15
, pp. 7661-7667
-
-
Baughn, L.B.1
Di, L.M.2
Wu, K.3
Toogood, P.L.4
Louie, T.5
Gottschalk, R.6
Niesvizky, R.7
Cho, H.8
Ely, S.9
Moore, M.A.S.10
Chen-Kiang, S.11
-
46
-
-
76049104235
-
PD 0332991, a selective cyclin D kinase 4/6 inhibitor, preferentially inhibits proliferation of luminal estrogen receptor-positive human breast cancer cell lines in vitro
-
Finn RS, Dering J, Conklin D, et al. PD 0332991, a selective cyclin D kinase 4/6 inhibitor, preferentially inhibits proliferation of luminal estrogen receptor-positive human breast cancer cell lines in vitro. Breast Cancer Res. 2009;11(5):R77.
-
(2009)
Breast Cancer Res
, vol.11
, Issue.5
-
-
Finn, R.S.1
Dering, J.2
Conklin, D.3
-
47
-
-
77954757207
-
Therapeutic CDK4/6 inhibition in breast cancer: Key mechanisms of response and failure
-
Dean JL, Thangavel C, McClendon AK, Reed CA, Knudsen ES. Therapeutic CDK4/6 inhibition in breast cancer: key mechanisms of response and failure. Oncogene. 2010;29(28):4018-4032.
-
(2010)
Oncogene
, vol.29
, Issue.28
, pp. 4018-4032
-
-
Dean, J.L.1
Thangavel, C.2
McClendon, A.K.3
Reed, C.A.4
Knudsen, E.S.5
-
48
-
-
79952710710
-
Expression of p16 and Retinoblastoma Determines Response to CDK4/6 Inhibition in Ovarian Cancer
-
Konecny GE, Winterhoff B, Kolarova T, et al. Expression of p16 and Retinoblastoma Determines Response to CDK4/6 Inhibition in Ovarian Cancer. Clin Cancer Res. 2011;17(6): 1591-1602.
-
(2011)
Clin Cancer Res
, vol.17
, Issue.6
, pp. 1591-1602
-
-
Konecny, G.E.1
Winterhoff, B.2
Kolarova, T.3
-
49
-
-
77954279920
-
A synthetic lethal interaction between K-Ras oncogenes and Cdk4 unveils a therapeutic strategy for non-small cell lung carcinoma
-
Puyol M, Martin A, Dubus P, et al. A synthetic lethal interaction between K-Ras oncogenes and Cdk4 unveils a therapeutic strategy for non-small cell lung carcinoma. Cancer Cell. 2010;18(1):63-73.
-
(2010)
Cancer Cell
, vol.18
, Issue.1
, pp. 63-73
-
-
Puyol, M.1
Martin, A.2
Dubus, P.3
-
50
-
-
85117738854
-
Phase I/II pharmacodynamic trial of PD0332991 in patients with KRAS mutant colorectal cancer
-
abstract
-
O'Dwyer PJ, Perini R, DeMichele A, et al. Phase I/II pharmacodynamic trial of PD0332991 in patients with KRAS mutant colorectal cancer [abstract]. Ann Oncol. 2011;22(suppl 3):PP01.
-
(2011)
Ann Oncol
, vol.22
, Issue.SUPPL. 3
-
-
O'Dwyer, P.J.1
Perini, R.2
DeMichele, A.3
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