Angiotensin-converting enzyme 2 activator diminazene aceturate prevents lipopolysaccharide-induced inflammation by inhibiting MAPK and NF-ΚB pathways in human retinal pigment epithelium

Journal of Neuroinflammation

Volumn 13, Issue 1, 2016, Pages

  Tao, Lifei ^a   Qiu, Yiguo ^a   Fu, Xinyu ^a   Lin, Ru ^a   Lei, Chunyan ^a   Wang, Jiaming ^a   Lei, Bo ^a  

^a THE FIRST AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

Angiotensin converting enzyme 2; Diminazene aceturate; Inflammation; MAPK; NF B

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 2 RECEPTOR; ANGIOTENSIN CONVERTING ENZYME 2; ANGIOTENSIN II; ANGIOTENSIN[1-7]; ANGIOTENSIN[1-7][7 DEXTRO ALANINE]; DIMINAZENE ACETURATE; I KAPPA B; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; MONOCYTE CHEMOTACTIC PROTEIN 1; PHOSPHOPROTEIN; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; CYTOKINE; DIMINAZENE; DIPEPTIDYL CARBOXYPEPTIDASE; ENZYME ACTIVATOR; I KAPPA B BETA; MITOGEN ACTIVATED PROTEIN KINASE KINASE;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; ENZYME PHOSPHORYLATION; EYE PROTECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; PIGMENT EPITHELIUM; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RETINITIS; SIGNAL TRANSDUCTION; CELL CULTURE; CELL SURVIVAL; CYTOLOGY; DOSE RESPONSE; DRUG EFFECTS; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; RETINA; RETINAL PIGMENT EPITHELIUM; TIME FACTOR;

CELL SURVIVAL; CELLS, CULTURED; CYTOKINES; DIMINAZENE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; HUMANS; I-KAPPA B PROTEINS; LIPOPOLYSACCHARIDES; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NF-KAPPA B; PEPTIDYL-DIPEPTIDASE A; RETINA; RETINAL PIGMENT EPITHELIUM; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 84957557356     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/s12974-016-0489-7     Document Type: Article

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