Progression of lipopolysaccharide signal pathway

Journal of Central South University (Medical Sciences)

Volumn 31, Issue 1, 2006, Pages 141-145

  Yang, Yi Xin ^a   Li, Gui Yuan ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Lipopolysaccharide; MAP kinase pathway; NF B pathway

Indexed keywords

CD14 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; LIPOPOLYSACCHARIDE BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6;

GRAM NEGATIVE BACTERIUM; HOST RESISTANCE; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; REVIEW; SIGNAL TRANSDUCTION;

ACUTE-PHASE PROTEINS; ANTIGENS, CD14; CARRIER PROTEINS; GRAM-NEGATIVE BACTERIA; LIPOPOLYSACCHARIDES; MEMBRANE GLYCOPROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NF-KAPPA B; SIGNAL TRANSDUCTION;

EID: 33644916106     PISSN: 16727347     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (26)

1. Diks SH, Richel DJ, Peppelenbosch MP. LPS signal transduction: the picture is becoming more complex [J]. Curr Top Med Chem, 2004, 4(11): 1115-1126.
2. Palsson-McDermoll EM, O'Neill LA. Signal transduction by the lipopolysaccharide receptor, Toll-like receptor-4 [J]. Immunology, 2004, 113(2): 153-162.
3. Weiss J. Bactericidal/permeability-increasing protein (BPI) and lipopolysa-ccharide-binding protein (LBP): structure, function and regulation in host defence against Gram-negative bacteria [J]. Biochem Soc Trans, 2003, 31 (Pt 4): 785-790.
4. Bingle CD, Craven CJ. Meet the relatives: a family of BPI- and LBP-related proteins [J]. Trends Immunol, 2004, 25(2): 53-55.
5. Bingle CD, Gorr SU. Host defense in oral and airway epithelia; chromosome 20 contributes a new protein family [J]. Int J Biochem Cell Biol, 2004, 36(11): 2144-2152.
6. Geetha C, Venkatesh SG, Dunn BH, et al. Expression and antibacterial activity of human parotid secretory protein (PSP) [J]. Biochem Soc Trans, 2003, 31 (Pt 4): 815-818.
7. Geetha C, Venkatesh SG, Bingle L, et al. Design and validation of anti-inflammatory peptides from human parotid secretory protein [J]. J Dent Res, 2005, 84(2): 149-153.
8. Zhou HD, Li GY, Yang YX, et al. Intraeellular co-localization of SPLUNC, protein with nanobacteria in nasopharyngeal carcinoma epithelia HNE, cells depended on the bactericidal permeability increasing protein domain[J]. Mol Immunol, 2005, (Epub ahead of print).
9. Pugin J, Schurer MC, Letureq D, et al. Lipopolyscchride-binding protein and soluble CDI4 [J]. Proc Nail Acad Sci, 1993, 90: 2744-2748.
10. Medzhitov R, Preston-Hurlburt P, Janeway CA Jr. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity[J]. Nature, 1997, 388(6640): 394-397.
11. Underhill DM, and A. Ozinsky. Toll-like receptors; key mediators of microbe detection[J]. Curr Opin Immunol, 2002, 14: 103-110.
12. Monick MM, Yarovinsky TO, Powers LS, et al. Respiratory syncytial virus up-regulates TLR4 and sensitizes airway epithelial cells to endotoxinfj]. J BM Chem, 2003, 278(52): 53035-53044.
13. Abreu MT, Vora P, Faure E, et al. Decreased expression of Toll-like receptor-4 and MD-2 correlates with intestinal epithelial cell protection against dysregulated proinflammatory gene expression in response to bacterial lipopolysaccharide [J]. J Immunol, 2001, 167(3): 1609-1616.
14. Youn HS, Lee JY, Fitzgerald KA, et. al. Specific Inhibition of MyD88-Independent Signaling Pathways of TLR3 and TLR4 by Resveratrol: Molecular Targets Are TBK1 and RIP1 in TRIE Complex [J]. J Immunol, 2005, 175(5): 3339-3346.
15. Rao N, Nguyen S, Ngo K, et al. A novel splice variant of interleukin-1 receptor (IL-1R)-associated kinase 1 plays a negative regulatory role in toll/IL-1R-induced inflammatory signaling[J]. Mol Cell Biol, 2005, 25(15): 6521-6532.
16. Muzio M, Natoli G, Saccani S, et al. The human toll signaling pathway: divergence of nuclear factor κB and JNK/SAPK activation upstream of tumor necrosis factor receptor associated factor 6 (TKAFO)[J]. J Exp Med, 1998, 187(12): 2097-2101.
17. Kawai, T, Adachi O, Ogawa T, et al. Unresponsiveness of MyD88-defielent mice to endotoxin [J]. Immunity, 1999, 11 (1): 115-122.
18. Fitzgerald KA, Palsson-McDermott EM, Bowie AG, et al. Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction [J]. Nature, 2001, 413(6851): 78-83.
19. Horng T, Barton GM, Medzhitov R. TIRAP; an adapter molecule in the Toll signaling pathway [J]. Nat Immunol, 2001, 2(9): 835-841.
20. Shishodia S, Koul D, Aggarwal BB. Cyclooxygenase (COX)-2 inhibitor celecoxib abrogates TNF-induced NF-kappa B activation through inhibition of activation of I kappa B alpha kinase and Akt in human non-small cell lung carcinoma: correlation with suppression of COX-2 synthesis[J]. J Immunol, 2004, 173(3): 2011-2022.
21. Dunn KL, Kspino PS, Drobic B, He S, Davie JR. The Ras-MAPK signal transduction pathway, cancer and chromatin remodeling[J]. Biochem Cell Biol, 2005, 83(1): 1-14.
22. Carl VS, Brown-Steinke K, Nicklin MJ, et. al. Toll-like receptor 2 and 4 (TLR2 and TLR4) agonists differentially regulate secretory interleukin-1 receptor antagonist gene expression in macrophages [J]. J Biol Chem, 2002, 277(20): 17448-17456.
23. Arndl PG, Suzuki N, Avdi NJ, et al. Lipopolysaccharide-induced c-Jun NH2-terminal kinase activation in human neutrophils; role of phosphalidylinositol 3-Kinase and Syk-mediated palhways [J]. J Biol Chem, 2004, 279(12): 10883-10891.
24. Ballaz S, Mulshine JL. The polential contributions of chronic inflammation to lung carcinogenesis [J]. Clin Lung Cancer, 2003, 5 (1): 46-62.
25. Basak C, Pathak SK, Bhattacharyya A, et al. NF-kappaB- and C/FBPbeta-driven interleukm-1 beta gene expression and PAKl-mediated caspase-1 activation play essential roles in interleukin-1 beta release from Helicobacter pylori lipopolysaccharide-stimulated macrophages[J]. J Biol Chem, 2005, 280(6): 4279-4288.
26. Luo JL, Maeda S, Hsu LC, et al. Inhibition of NF-kappaB in cancer cells converts inflammation- induced tumor growth mediated by TNF-alpha to TRAIL-mediated tumor regression[J]. Cancer Cell, 2004, 6(3): 297-305.