CD200R1 agonist attenuates LPS-induced inflammatory response in human renal proximal tubular epithelial cells by regulating TLR4-MyD88-TAK1-mediated NF-κB and MAPK pathway

Biochemical and Biophysical Research Communications

Volumn 460, Issue 2, 2015, Pages 287-294

  Ding, Yan ^a,d   Yang, Huilan ^b   Xiang, Wei ^a   He, Xiaojie ^c   Liao, Wang ^d   Yi, Zhuwen ^c  

^a Department of Dermatology   (China)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

^c CENTRAL SOUTH UNIVERSITY   (China)

^d HAINAN GENERAL HOSPITAL   (China)

Author keywords

CD200Fc; Human renal proximal tubular epithelial cells; Inflammation; MAPK; NF B; TLR4

Indexed keywords

CD200R1 PROTEIN, HUMAN; CELL SURFACE RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MAP KINASE KINASE KINASE 7; MEMBRANE ANTIGEN; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; MYD88 PROTEIN, HUMAN; MYELOID DIFFERENTIATION FACTOR 88; TLR4 PROTEIN, HUMAN; TOLL LIKE RECEPTOR 4;

AGONISTS; CELL CULTURE; DRUG EFFECTS; ENZYMOLOGY; EPITHELIUM CELL; HUMAN; INFLAMMATION; KIDNEY PROXIMAL TUBULE; METABOLISM; SIGNAL TRANSDUCTION;

ANTIGENS, SURFACE; CELLS, CULTURED; EPITHELIAL CELLS; HUMANS; INFLAMMATION; KIDNEY TUBULES, PROXIMAL; LIPOPOLYSACCHARIDES; MAP KINASE KINASE KINASES; MAP KINASE SIGNALING SYSTEM; MYELOID DIFFERENTIATION FACTOR 88; NF-KAPPA B; RECEPTORS, CELL SURFACE; TOLL-LIKE RECEPTOR 4;

EID: 84937765348     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.03.026     Document Type: Article

References (26)

1. R.J. Cook, D.D. Gladman, D. Pericak, and M.B. Urowitz Prediction of short term mortality in systemic lupus erythematosus with time dependent measures of disease activity J. Rheumatol. 27 2000 1892 1895
2. C.C. Mok, R.C. Kwok, and P.S. Yip Effect of renal disease on the standardized mortality ratio and life expectancy of patients with systemic lupus erythematosus Arthritis Rheum. 65 2013 2154 2160
3. M.M. Ward Changes in the incidence of endstage renal disease due to lupus nephritis in the United States, 1996-2004 J. Rheumatol. 36 2009 63 67
4. F. Yuan, D.E. Tabor, R.K. Nelson, H. Yuan, Y. Zhang, J. Nuxoll, K.K. Bynote, S.M. Lele, D. Wang, and K.A. Gould A dexamethasone prodrug reduces the renal macrophage response and provides enhanced resolution of established murine lupus nephritis PLoS One 8 2013 e81483
5. D.A. Costello, A. Lyons, S. Denieffe, T.C. Browne, F.F. Cox, and M.A. Lynch Long term potentiation is impaired in membrane glycoprotein CD200-deficient mice: a role for toll-like receptor activation J. Biol. Chem. 286 2011 34722 34732
6. W. Masocha Systemic lipopolysaccharide (LPS)-induced microglial activation results in different temporal reduction of CD200 and CD200 receptor gene expression in the brain J. Neuroimmunol. 214 2009 78 82
7. S. Zhang, H. Cherwinski, J.D. Sedgwick, and J.H. Phillips Molecular mechanisms of CD200 inhibition of mast cell activation J. Immunol. 173 2004 6786 6793
8. R.M. Gorczynski, Z. Chen, L. Lee, K. Yu, and J. Hu Anti-CD200R ameliorates collagen-induced arthritis in mice Clin. Immunol. 104 2002 256 264
9. R.M. Gorczynski, Z. Chen, K. Yu, and J. Hu CD200 immunoadhesin suppresses collagen-induced arthritis in mice Clin. Immunol. 101 2001 328 334
10. T. Chitnis, J. Imitola, Y. Wang, W. Elyaman, P. Chawla, M. Sharuk, K. Raddassi, R.T. Bronson, and S.J. Khoury Elevated neuronal expression of CD200 protects Wlds mice from inflammation-mediated neurodegeneration Am. J. Pathol. 170 2007 1695 1712
11. R.M. Hoek, S.R. Ruuls, C.A. Murphy, G.J. Wright, R. Goddard, S.M. Zurawski, B. Blom, M.E. Homola, W.J. Streit, M.H. Brown, A.N. Barclay, and J.D. Sedgwick Down-regulation of the macrophage lineage through interaction with OX2 (CD200) Science 290 2000 1768 1771
12. C. Broderick, R.M. Hoek, J.V. Forrester, J. Liversidge, J.D. Sedgwick, and A.D. Dick Constitutive retinal CD200 expression regulates resident microglia and activation state of inflammatory cells during experimental autoimmune uveoretinitis Am. J. Pathol. 161 2002 1669 1677
13. Y. Liu, Y. Bando, D. Vargas-Lowy, W. Elyaman, S.J. Khoury, T. Huang, K. Reif, and T. Chitnis CD200R1 agonist attenuates mechanisms of chronic disease in a murine model of multiple sclerosis J. Neurosci. 30 2010 2025 2038
14. U. Kunter, S. Daniel, M.B. Arvelo, J. Choi, T. Shukri, V.I. Patel, C.R. Longo, S.T. Scali, G. Shrikhande, E. Rocha, E. Czismadia, C. Mottley, S.T. Grey, J. Floege, and C. Ferran Combined expression of A1 and A20 achieves optimal protection of renal proximal tubular epithelial cells Kidney Int. 68 2005 1520 1532
15. B. Li, Y. Yue, C. Dong, Y. Shi, and S. Xiong Blockade of macrophage autophagy ameliorates activated lymphocytes-derived DNA induced murine lupus possibly via inhibition of proinflammatory cytokine production Clin. Exp. Rheumatol. 32 2014 705 714
16. N. Ronda, P. Cravedi, L. Benozzi, P. Lunghi, A. Bonati, L. Allegri, M.L. Carnevali, C. Caserta, A. Borghetti, and C. Buzio Early proinflammatory activation of renal tubular cells by normal and pathologic IgG Nephron Exp. Nephrol. 100 2005 e77 84
17. M. Venegas-Pont, M.B. Manigrasso, S.C. Grifoni, B.B. LaMarca, C. Maric, L.C. Racusen, P.H. Glover, A.V. Jones, H.A. Drummond, and M.J. Ryan Tumor necrosis factor-alpha antagonist etanercept decreases blood pressure and protects the kidney in a mouse model of systemic lupus erythematosus Hypertension 56 2010 643 649
18. L. Hang, J.H. Slack, C. Amundson, S. Izui, A.N. Theofilopoulos, and F.J. Dixon Induction of murine autoimmune disease by chronic polyclonal B cell activation J. Exp. Med. 157 1983 874 883
19. S.A. Summers, A. Hoi, O.M. Steinmetz, K.M. O'Sullivan, J.D. Ooi, D. Odobasic, S. Akira, A.R. Kitching, and S.R. Holdsworth TLR9 and TLR4 are required for the development of autoimmunity and lupus nephritis in pristane nephropathy J. Autoimmun. 35 2010 291 298
20. A. Lartigue, N. Colliou, S. Calbo, A. Francois, S. Jacquot, C. Arnoult, F. Tron, D. Gilbert, and P. Musette Critical role of TLR2 and TLR4 in autoantibody production and glomerulonephritis in lpr mutation-induced mouse lupus J. Immunol. 183 2009 6207 6216
21. K.E. Lee, E.Y. Kim, C.S. Kim, J.S. Choi, E.H. Bae, S.K. Ma, K.K. Kim, J.U. Lee, and S.W. Kim Macrophage-stimulating protein attenuates gentamicin-induced inflammation and apoptosis in human renal proximal tubular epithelial cells Biochem. Biophys. Res. Commun. 434 2013 527 533
22. H. Kimura, D. Mikami, K. Kamiyama, H. Sugimoto, K. Kasuno, N. Takahashi, H. Yoshida, and M. Iwano Telmisartan, a possible PPAR-delta agonist, reduces TNF-alpha-stimulated VEGF-C production by inhibiting the p38MAPK/HSP27 pathway in human proximal renal tubular cells Biochem. Biophys. Res. Commun. 454 2014 320 327
23. M.C. Jenmalm, H. Cherwinski, E.P. Bowman, J.H. Phillips, and J.D. Sedgwick Regulation of myeloid cell function through the CD200 receptor J. Immunol. 176 2006 191 199
24. I. Boudakov, J. Liu, N. Fan, P. Gulay, K. Wong, and R.M. Gorczynski Mice lacking CD200R1 show absence of suppression of lipopolysaccharide-induced tumor necrosis factor-alpha and mixed leukocyte culture responses by CD200 Transplantation 84 2007 251 257
25. M. Andreucci, G. Lucisano, T. Faga, B. Bertucci, O. Tamburrini, A. Pisani, M. Sabbatini, S. Salzano, M. Vitale, G. Fuiano, and A. Michael Differential activation of signaling pathways involved in cell death, survival and inflammation by radiocontrast media in human renal proximal tubular cells Toxicol. Sci. 119 2011 408 416
26. Y. Guo, W. Yuan, L. Wang, M. Shang, and Y. Peng Parathyroid hormone-potentiated connective tissue growth factor expression in human renal proximal tubular cells through activating the MAPK and NF-kappaB signalling pathways Nephrol. Dial. Transpl. 26 2011 839 847