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Volumn 71, Issue 3, 2016, Pages 295-307

Barrier function of the nasal mucosa in health and type-2 biased airway diseases

Author keywords

allergic rhinitis; chronic rhinosinusitis with nasal polyps; eosinophil extracellular traps; immune response; nasal epithelial barrier

Indexed keywords

ANTIINFECTIVE AGENT; CHEMOKINE; CYTOKINE; DUPILUMAB; GLUCOCORTICOID; OMALIZUMAB; ANTIMICROBIAL CATIONIC PEPTIDE;

EID: 84957436413     PISSN: 01054538     EISSN: 13989995     Source Type: Journal    
DOI: 10.1111/all.12809     Document Type: Review
Times cited : (106)

References (108)
  • 2
    • 84869147350 scopus 로고    scopus 로고
    • Defective epithelial barrier in chronic rhinosinusitis: The regulation of tight junctions by IFN-γ and IL-4
    • Soyka MB, Wawrzyniak P, Eiwegger T, Holzmann D, Treis A, Wanke K, et al., Defective epithelial barrier in chronic rhinosinusitis: the regulation of tight junctions by IFN-γ and IL-4. J Allergy Clin Immunol 2012; 130: 1087-1096.
    • (2012) J Allergy Clin Immunol , vol.130 , pp. 1087-1096
    • Soyka, M.B.1    Wawrzyniak, P.2    Eiwegger, T.3    Holzmann, D.4    Treis, A.5    Wanke, K.6
  • 6
    • 33745698838 scopus 로고    scopus 로고
    • Blocking of protease allergens with inhibitors reduces allergic responses in allergic rhinitis and other allergic diseases
    • Suzuki M, Itoh M, Ohta N, Nakamura Y, Moriyama A, Matsumoto T, et al., Blocking of protease allergens with inhibitors reduces allergic responses in allergic rhinitis and other allergic diseases. Acta Otolaryngol 2006; 126: 746-751.
    • (2006) Acta Otolaryngol , vol.126 , pp. 746-751
    • Suzuki, M.1    Itoh, M.2    Ohta, N.3    Nakamura, Y.4    Moriyama, A.5    Matsumoto, T.6
  • 7
    • 84941186673 scopus 로고    scopus 로고
    • Oncostatin M promotes mucosal epithelial barrier dysfunction, and its expression is increased in patients with eosinophilic mucosal disease
    • Pothoven K, Norton JE, Hulse KE, Suh LA, Carter RG, Rocci E, et al., Oncostatin M promotes mucosal epithelial barrier dysfunction, and its expression is increased in patients with eosinophilic mucosal disease. J Allergy Clin Immunol 2015; 136: 737-746.
    • (2015) J Allergy Clin Immunol , vol.136 , pp. 737-746
    • Pothoven, K.1    Norton, J.E.2    Hulse, K.E.3    Suh, L.A.4    Carter, R.G.5    Rocci, E.6
  • 8
    • 84857734855 scopus 로고    scopus 로고
    • Acquired cilia dysfunction in chronic rhinosinusitis
    • Gudis D, Zhao KQ, Cohen NA,. Acquired cilia dysfunction in chronic rhinosinusitis. Am J Rhinol Allergy 2012; 26: 1-6.
    • (2012) Am J Rhinol Allergy , vol.26 , pp. 1-6
    • Gudis, D.1    Zhao, K.Q.2    Cohen, N.A.3
  • 10
    • 84862089589 scopus 로고    scopus 로고
    • Role of innate immunity in the pathogenesis of allergic rhinitis
    • Melvin TA, Ramanathan M Jr,. Role of innate immunity in the pathogenesis of allergic rhinitis. Curr Opin Otolaryngol Head Neck Surg 2012; 20: 194-198.
    • (2012) Curr Opin Otolaryngol Head Neck Surg , vol.20 , pp. 194-198
    • Melvin, T.A.1    Ramanathan, M.2
  • 11
    • 84862017237 scopus 로고    scopus 로고
    • Reduced expression of antimicrobial PLUNC proteins in nasal polyp tissues of patients with chronic rhinosinusitis
    • Seshadri S, Lin DC, Rosati M, Carter RG, Norton JE, Suh L, et al., Reduced expression of antimicrobial PLUNC proteins in nasal polyp tissues of patients with chronic rhinosinusitis. Allergy 2012; 67: 920-928.
    • (2012) Allergy , vol.67 , pp. 920-928
    • Seshadri, S.1    Lin, D.C.2    Rosati, M.3    Carter, R.G.4    Norton, J.E.5    Suh, L.6
  • 12
    • 42449114052 scopus 로고    scopus 로고
    • Th2 cytokines associated with chronic rhinosinusitis with polyps down-regulate the antimicrobial immune function of human sinonasal epithelial cells
    • Ramanathan M Jr, Lee WK, Spannhake EW, Lane AP,. Th2 cytokines associated with chronic rhinosinusitis with polyps down-regulate the antimicrobial immune function of human sinonasal epithelial cells. Am J Rhinol 2008; 22: 115-121.
    • (2008) Am J Rhinol , vol.22 , pp. 115-121
    • Ramanathan, M.1    Lee, W.K.2    Spannhake, E.W.3    Lane, A.P.4
  • 13
    • 84920874768 scopus 로고    scopus 로고
    • Role of the bitter taste receptor T2R38 in upper respiratory infection and chronic rhinosinusitis
    • Lee RJ, Cohen NA,. Role of the bitter taste receptor T2R38 in upper respiratory infection and chronic rhinosinusitis. Curr Opin Allergy Clin Immunol 2015; 15: 14-20.
    • (2015) Curr Opin Allergy Clin Immunol , vol.15 , pp. 14-20
    • Lee, R.J.1    Cohen, N.A.2
  • 14
    • 84868610108 scopus 로고    scopus 로고
    • T2R38 taste receptor polymorphisms underlie susceptibility to upper respiratory infection
    • Lee RJ, Xiong G, Kofonow JM, Chen B, Lysenko A, Jiang P, et al., T2R38 taste receptor polymorphisms underlie susceptibility to upper respiratory infection. J Clin Invest 2012; 122: 4145-4159.
    • (2012) J Clin Invest , vol.122 , pp. 4145-4159
    • Lee, R.J.1    Xiong, G.2    Kofonow, J.M.3    Chen, B.4    Lysenko, A.5    Jiang, P.6
  • 15
    • 84957454593 scopus 로고    scopus 로고
    • Th2 biased upper airway inflammation is associated with an impaired response to viral infection with Herpes simplex virus 1
    • Dec 23. [Epub ahead of print]
    • Lan F, Wang XD, Nauwynck JH, Holtappels G, Zhang L, Johnston LS, et al., Th2 biased upper airway inflammation is associated with an impaired response to viral infection with Herpes simplex virus 1. Rhinology 2015, Dec 23. [Epub ahead of print]. http://www.ncbi.nlm.nih.gov/pubmed/26702454
    • (2015) Rhinology
    • Lan, F.1    Wang, X.D.2    Nauwynck, J.H.3    Holtappels, G.4    Zhang, L.5    Johnston, L.S.6
  • 16
    • 84863115029 scopus 로고    scopus 로고
    • Herpes simplex virus type 1 infection facilitates invasion of Staphylococcus aureus into the nasal mucosa and nasal polyp tissue
    • Wang X, Zhang N, Glorieux S, Holtappels G, Vaneechoutte M, Krysko O, et al., Herpes simplex virus type 1 infection facilitates invasion of Staphylococcus aureus into the nasal mucosa and nasal polyp tissue. PLoS One 2012; 7: e39875.
    • (2012) PLoS One , vol.7 , pp. e39875
    • Wang, X.1    Zhang, N.2    Glorieux, S.3    Holtappels, G.4    Vaneechoutte, M.5    Krysko, O.6
  • 17
    • 79551668577 scopus 로고    scopus 로고
    • Alternatively activated macrophages and impaired phagocytosis of S. Aureus in chronic rhinosinusitis
    • Krysko O, Holtappels G, Zhang N, Kubica M, Deswarte K, Derycke L, et al., Alternatively activated macrophages and impaired phagocytosis of S. aureus in chronic rhinosinusitis. Allergy 2011; 66: 396-403.
    • (2011) Allergy , vol.66 , pp. 396-403
    • Krysko, O.1    Holtappels, G.2    Zhang, N.3    Kubica, M.4    Deswarte, K.5    Derycke, L.6
  • 20
    • 80052272960 scopus 로고    scopus 로고
    • Reduced diversity of the intestinal microbiota during infancy is associated with increased risk of allergic disease at school age
    • Bisgaard H, Li N, Bonnelykke K, Chawes BL, Skov T, Paludan-Muller G, et al., Reduced diversity of the intestinal microbiota during infancy is associated with increased risk of allergic disease at school age. J Allergy Clin Immunol 2011; 128: 646-652.
    • (2011) J Allergy Clin Immunol , vol.128 , pp. 646-652
    • Bisgaard, H.1    Li, N.2    Bonnelykke, K.3    Chawes, B.L.4    Skov, T.5    Paludan-Muller, G.6
  • 22
    • 84855206779 scopus 로고    scopus 로고
    • Regulation of inflammatory responses by the commensal microbiota
    • Marsland BJ,. Regulation of inflammatory responses by the commensal microbiota. Thorax 2012; 67: 93-94.
    • (2012) Thorax , vol.67 , pp. 93-94
    • Marsland, B.J.1
  • 23
    • 84856242309 scopus 로고    scopus 로고
    • Microbiome complexity and staphylococcus aureus in chronic rhinosinusitis
    • Feazel LM, Robertson CE, Ramakrishnan VR, Frank DN,. Microbiome complexity and staphylococcus aureus in chronic rhinosinusitis. Laryngoscope 2012; 122: 467-472.
    • (2012) Laryngoscope , vol.122 , pp. 467-472
    • Feazel, L.M.1    Robertson, C.E.2    Ramakrishnan, V.R.3    Frank, D.N.4
  • 24
    • 84895555213 scopus 로고    scopus 로고
    • Decreased diversity of nasal microbiota and their secreted extracellular vesicles in patients with chronic rhinosinusitis based on a metagenomic analysis
    • Choi EB, Hong SW, Kim DK, Jeon SG, Kim KR, Cho SH, et al., Decreased diversity of nasal microbiota and their secreted extracellular vesicles in patients with chronic rhinosinusitis based on a metagenomic analysis. Allergy 2014; 69: 517-526.
    • (2014) Allergy , vol.69 , pp. 517-526
    • Choi, E.B.1    Hong, S.W.2    Kim, D.K.3    Jeon, S.G.4    Kim, K.R.5    Cho, S.H.6
  • 25
    • 80052661706 scopus 로고    scopus 로고
    • Bacterial colonization is associated with different inflammatory pattern in rhinosinusitis with nasal polyps
    • Ba L, Zhang N, Meng J, Zhang J, Lin P, Zhou P, et al., Bacterial colonization is associated with different inflammatory pattern in rhinosinusitis with nasal polyps. Allergy 2011; 66: 1296-1303.
    • (2011) Allergy , vol.66 , pp. 1296-1303
    • Ba, L.1    Zhang, N.2    Meng, J.3    Zhang, J.4    Lin, P.5    Zhou, P.6
  • 26
    • 84864313480 scopus 로고    scopus 로고
    • Chronic rhinosinusitis and asthma: Novel understanding of the role of IgE "above atopy"
    • Bachert C, Zhang N,. Chronic rhinosinusitis and asthma: novel understanding of the role of IgE "above atopy". J Intern Med 2012; 272: 133-143.
    • (2012) J Intern Med , vol.272 , pp. 133-143
    • Bachert, C.1    Zhang, N.2
  • 27
    • 70449719323 scopus 로고    scopus 로고
    • Detection of Staphylococcus aureus in nasal tissue with peptide nucleic acid - Fluorescence in situ hybridization
    • Corriveau MN, Zhang N, Holtappels G, Van Roy N, Bachert C,. Detection of Staphylococcus aureus in nasal tissue with peptide nucleic acid-fluorescence in situ hybridization. Am J Rhinol Allergy 2009; 23: 461-465.
    • (2009) Am J Rhinol Allergy , vol.23 , pp. 461-465
    • Corriveau, M.N.1    Zhang, N.2    Holtappels, G.3    Van Roy, N.4    Bachert, C.5
  • 30
    • 33744748625 scopus 로고    scopus 로고
    • Regulation of mucin genes in chronic inflammatory airway diseases
    • Voynow JA, Gendler SJ, Rose MC,. Regulation of mucin genes in chronic inflammatory airway diseases. Am J Respir Cell Mol Biol 2006; 34: 661-665.
    • (2006) Am J Respir Cell Mol Biol , vol.34 , pp. 661-665
    • Voynow, J.A.1    Gendler, S.J.2    Rose, M.C.3
  • 31
    • 84893342186 scopus 로고    scopus 로고
    • Staphylococcus enterotoxin A induces MUC5B expression via Toll-like receptor 2, extracellular signal-regulated kinase 1/2, and p38 mitogen-activated protein kinase in human airway epithelial cells
    • Song SY, Chi DH, Bae CH, Kim YD,. Staphylococcus enterotoxin A induces MUC5B expression via Toll-like receptor 2, extracellular signal-regulated kinase 1/2, and p38 mitogen-activated protein kinase in human airway epithelial cells. Am J Rhinol Allergy 2014; 28: e25-e30.
    • (2014) Am J Rhinol Allergy , vol.28 , pp. e25-e30
    • Song, S.Y.1    Chi, D.H.2    Bae, C.H.3    Kim, Y.D.4
  • 32
    • 78649735324 scopus 로고    scopus 로고
    • Airway mucus function and dysfunction
    • Fahy JV, Dickey BF,. Airway mucus function and dysfunction. N Engl J Med 2010; 363: 2233-2247.
    • (2010) N Engl J Med , vol.363 , pp. 2233-2247
    • Fahy, J.V.1    Dickey, B.F.2
  • 33
    • 84929996502 scopus 로고    scopus 로고
    • TMEM16A-mediated mucin secretion in IL-13-induced nasal epithelial cells from chronic rhinosinusitis patients
    • Zhang Y, Wang X, Wang H, Jiao J, Li Y, Fan E, et al., TMEM16A-mediated mucin secretion in IL-13-induced nasal epithelial cells from chronic rhinosinusitis patients. Allergy Asthma Immunol Res 2015; 7: 367-375.
    • (2015) Allergy Asthma Immunol Res , vol.7 , pp. 367-375
    • Zhang, Y.1    Wang, X.2    Wang, H.3    Jiao, J.4    Li, Y.5    Fan, E.6
  • 35
    • 84892403891 scopus 로고    scopus 로고
    • The development of nasal polyp disease involves early nasal mucosal inflammation and remodelling
    • Meng J, Zhou P, Liu Y, Liu F, Yi X, Liu S, et al., The development of nasal polyp disease involves early nasal mucosal inflammation and remodelling. PLoS One 2013; 8: e82373.
    • (2013) PLoS One , vol.8 , pp. e82373
    • Meng, J.1    Zhou, P.2    Liu, Y.3    Liu, F.4    Yi, X.5    Liu, S.6
  • 36
    • 79960015037 scopus 로고    scopus 로고
    • Pollen proteases compromise the airway epithelial barrier through degradation of transmembrane adhesion proteins and lung bioactive peptides
    • Vinhas R, Cortes L, Cardoso I, Mendes VM, Manadas B, Todo-Bom A, et al., Pollen proteases compromise the airway epithelial barrier through degradation of transmembrane adhesion proteins and lung bioactive peptides. Allergy 2011; 66: 1088-1098.
    • (2011) Allergy , vol.66 , pp. 1088-1098
    • Vinhas, R.1    Cortes, L.2    Cardoso, I.3    Mendes, V.M.4    Manadas, B.5    Todo-Bom, A.6
  • 37
    • 33644908476 scopus 로고    scopus 로고
    • Pen ch 13 allergen induces secretion of mediators and degradation of occludin protein of human lung epithelial cells
    • Tai HY, Tam MF, Chou H, Peng HJ, Su SN, Perng DW, et al., Pen ch 13 allergen induces secretion of mediators and degradation of occludin protein of human lung epithelial cells. Allergy 2006; 61: 382-388.
    • (2006) Allergy , vol.61 , pp. 382-388
    • Tai, H.Y.1    Tam, M.F.2    Chou, H.3    Peng, H.J.4    Su, S.N.5    Perng, D.W.6
  • 39
    • 33846914242 scopus 로고    scopus 로고
    • Sinonasal epithelial cell expression of toll-like receptor 9 is decreased in chronic rhinosinusitis with polyps
    • Ramanathan M Jr, Lee WK, Dubin MG, Lin S, Spannhake EW, Lane AP,. Sinonasal epithelial cell expression of toll-like receptor 9 is decreased in chronic rhinosinusitis with polyps. Am J Rhinol 2007; 21: 110-116.
    • (2007) Am J Rhinol , vol.21 , pp. 110-116
    • Ramanathan, M.1    Lee, W.K.2    Dubin, M.G.3    Lin, S.4    Spannhake, E.W.5    Lane, A.P.6
  • 40
    • 54049104011 scopus 로고    scopus 로고
    • Toll-like receptor 2, 3, 4, 5 ligands and interleukin-4 synergistically induce TARC production in nasal polyp fibroblasts
    • Nonaka M, Ogihara N, Fukumoto A, Sakanushi A, Pawankar R, Yagi T,. Toll-like receptor 2, 3, 4, 5 ligands and interleukin-4 synergistically induce TARC production in nasal polyp fibroblasts. Auris Nasus Larynx 2008; 35: 515-520.
    • (2008) Auris Nasus Larynx , vol.35 , pp. 515-520
    • Nonaka, M.1    Ogihara, N.2    Fukumoto, A.3    Sakanushi, A.4    Pawankar, R.5    Yagi, T.6
  • 45
    • 84871710260 scopus 로고    scopus 로고
    • An insight into the diverse roles of surfactant proteins, SP-A and SP-D in innate and adaptive immunity
    • Nayak A, Dodagatta-Marri E, Tsolaki AG, Kishore U,. An insight into the diverse roles of surfactant proteins, SP-A and SP-D in innate and adaptive immunity. Front Immunol 2012; 3: 131.
    • (2012) Front Immunol , vol.3 , pp. 131
    • Nayak, A.1    Dodagatta-Marri, E.2    Tsolaki, A.G.3    Kishore, U.4
  • 46
    • 34250745760 scopus 로고    scopus 로고
    • Sinonasal surfactant protein A1, A2, and D gene expression in cystic fibrosis: A preliminary report
    • Woodworth BA, Wood R, Baatz JE, Schlosser RJ,. Sinonasal surfactant protein A1, A2, and D gene expression in cystic fibrosis: a preliminary report. Otolaryngol Head Neck Surg 2007; 137: 34-38.
    • (2007) Otolaryngol Head Neck Surg , vol.137 , pp. 34-38
    • Woodworth, B.A.1    Wood, R.2    Baatz, J.E.3    Schlosser, R.J.4
  • 47
    • 33846067633 scopus 로고    scopus 로고
    • Surfactant protein d expression in chronic rhinosinusitis patients and immune responses in vitro to Aspergillus and alternaria in a nasal explant model
    • Ooi EH, Wormald PJ, Carney AS, James CL, Tan LW,. Surfactant protein d expression in chronic rhinosinusitis patients and immune responses in vitro to Aspergillus and alternaria in a nasal explant model. Laryngoscope 2007; 117: 51-57.
    • (2007) Laryngoscope , vol.117 , pp. 51-57
    • Ooi, E.H.1    Wormald, P.J.2    Carney, A.S.3    James, C.L.4    Tan, L.W.5
  • 48
    • 52049100346 scopus 로고    scopus 로고
    • Enhanced expression of murine beta-defensins (MBD-1, -2,- 3, and -4) in upper and lower airway mucosa of influenza virus infected mice
    • Chong KT, Thangavel RR, Tang X,. Enhanced expression of murine beta-defensins (MBD-1, -2,- 3, and -4) in upper and lower airway mucosa of influenza virus infected mice. Virology 2008; 380: 136-143.
    • (2008) Virology , vol.380 , pp. 136-143
    • Chong, K.T.1    Thangavel, R.R.2    Tang, X.3
  • 50
    • 27744522948 scopus 로고    scopus 로고
    • Psoriasin, one of several new proteins identified in nasal lavage fluid from allergic and non-allergic individuals using 2-dimensional gel electrophoresis and mass spectrometry
    • Bryborn M, Adner M, Cardell LO,. Psoriasin, one of several new proteins identified in nasal lavage fluid from allergic and non-allergic individuals using 2-dimensional gel electrophoresis and mass spectrometry. Respir Res 2005; 6: 118.
    • (2005) Respir Res , vol.6 , pp. 118
    • Bryborn, M.1    Adner, M.2    Cardell, L.O.3
  • 51
    • 43549126463 scopus 로고    scopus 로고
    • Comprehensive evaluation of genetic variation in S100A7 suggests an association with the occurrence of allergic rhinitis
    • Bryborn M, Hallden C, Sall T, Adner M, Cardell LO,. Comprehensive evaluation of genetic variation in S100A7 suggests an association with the occurrence of allergic rhinitis. Respir Res 2008; 9: 29.
    • (2008) Respir Res , vol.9 , pp. 29
    • Bryborn, M.1    Hallden, C.2    Sall, T.3    Adner, M.4    Cardell, L.O.5
  • 52
    • 84857457223 scopus 로고    scopus 로고
    • Diminished levels of nasal S100A7 (psoriasin) in seasonal allergic rhinitis: An effect mediated by Th2 cytokines
    • Kvarnhammar AM, Rydberg C, Jarnkrants M, Eriksson M, Uddman R, Benson M, et al., Diminished levels of nasal S100A7 (psoriasin) in seasonal allergic rhinitis: an effect mediated by Th2 cytokines. Respir Res 2012; 13: 2.
    • (2012) Respir Res , vol.13 , pp. 2
    • Kvarnhammar, A.M.1    Rydberg, C.2    Jarnkrants, M.3    Eriksson, M.4    Uddman, R.5    Benson, M.6
  • 55
    • 33746047516 scopus 로고    scopus 로고
    • Human pulmonary surfactant protein D binds the extracellular domains of Toll-like receptors 2 and 4 through the carbohydrate recognition domain by a mechanism different from its binding to phosphatidylinositol and lipopolysaccharide
    • Ohya M, Nishitani C, Sano H, Yamada C, Mitsuzawa H, Shimizu T, et al., Human pulmonary surfactant protein D binds the extracellular domains of Toll-like receptors 2 and 4 through the carbohydrate recognition domain by a mechanism different from its binding to phosphatidylinositol and lipopolysaccharide. Biochemistry 2006; 45: 8657-8664.
    • (2006) Biochemistry , vol.45 , pp. 8657-8664
    • Ohya, M.1    Nishitani, C.2    Sano, H.3    Yamada, C.4    Mitsuzawa, H.5    Shimizu, T.6
  • 56
    • 34948900275 scopus 로고    scopus 로고
    • Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock
    • Vogl T, Tenbrock K, Ludwig S, Leukert N, Ehrhardt C, van Zoelen MA, et al., Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock. Nat Med 2007; 13: 1042-1049.
    • (2007) Nat Med , vol.13 , pp. 1042-1049
    • Vogl, T.1    Tenbrock, K.2    Ludwig, S.3    Leukert, N.4    Ehrhardt, C.5    Van Zoelen, M.A.6
  • 57
    • 84954290425 scopus 로고    scopus 로고
    • Differential release and deposition of S100A8/A9 proteins in inflamed upper airway tissue
    • Van Crombruggen K, Vogl T, Perez-Novo CA, Holtappels G, Bachert C,. Differential release and deposition of S100A8/A9 proteins in inflamed upper airway tissue. Eur Respir J 2016; 47: 264-274.
    • (2016) Eur Respir J , vol.47 , pp. 264-274
    • Van Crombruggen, K.1    Vogl, T.2    Perez-Novo, C.A.3    Holtappels, G.4    Bachert, C.5
  • 58
    • 77649261728 scopus 로고    scopus 로고
    • Evidence for diminished levels of epithelial psoriasin and calprotectin in chronic rhinosinusitis
    • Tieu DD, Peters AT, Carter RG, Suh L, Conley DB, Chandra R, et al., Evidence for diminished levels of epithelial psoriasin and calprotectin in chronic rhinosinusitis. J Allergy Clin Immunol 2010; 125: 667-675.
    • (2010) J Allergy Clin Immunol , vol.125 , pp. 667-675
    • Tieu, D.D.1    Peters, A.T.2    Carter, R.G.3    Suh, L.4    Conley, D.B.5    Chandra, R.6
  • 59
    • 47749113698 scopus 로고    scopus 로고
    • Eosinophil-derived neurotoxin/RNase 2: Connecting the past, the present and the future
    • Rosenberg HF,. Eosinophil-derived neurotoxin/RNase 2: connecting the past, the present and the future. Curr Pharm Biotechnol 2008; 9: 135-140.
    • (2008) Curr Pharm Biotechnol , vol.9 , pp. 135-140
    • Rosenberg, H.F.1
  • 60
    • 38749088662 scopus 로고    scopus 로고
    • Eosinophil-derived neurotoxin acts as an alarmin to activate the TLR2-MyD88 signal pathway in dendritic cells and enhances Th2 immune responses
    • Yang D, Chen Q, Su SB, Zhang P, Kurosaka K, Caspi RR, et al., Eosinophil-derived neurotoxin acts as an alarmin to activate the TLR2-MyD88 signal pathway in dendritic cells and enhances Th2 immune responses. J Exp Med 2008; 205: 79-90.
    • (2008) J Exp Med , vol.205 , pp. 79-90
    • Yang, D.1    Chen, Q.2    Su, S.B.3    Zhang, P.4    Kurosaka, K.5    Caspi, R.R.6
  • 61
    • 4644235588 scopus 로고    scopus 로고
    • Lysozyme levels in the nasal secretions of patients with perennial allergic rhinitis and recurrent sinusitis
    • Kalfa VC, Spector SL, Ganz T, Cole AM,. Lysozyme levels in the nasal secretions of patients with perennial allergic rhinitis and recurrent sinusitis. Ann Allergy Asthma Immunol 2004; 93: 288-292.
    • (2004) Ann Allergy Asthma Immunol , vol.93 , pp. 288-292
    • Kalfa, V.C.1    Spector, S.L.2    Ganz, T.3    Cole, A.M.4
  • 62
    • 0024436975 scopus 로고
    • Major basic protein and eosinophil-derived neurotoxin concentrations in nasal-lavage fluid after antigen challenge: Effect of systemic corticosteroids and relationship to eosinophil influx
    • Bascom R, Pipkorn U, Proud D, Dunnette S, Gleich GJ, Lichtenstein LM, et al., Major basic protein and eosinophil-derived neurotoxin concentrations in nasal-lavage fluid after antigen challenge: effect of systemic corticosteroids and relationship to eosinophil influx. J Allergy Clin Immunol 1989; 84: 338-346.
    • (1989) J Allergy Clin Immunol , vol.84 , pp. 338-346
    • Bascom, R.1    Pipkorn, U.2    Proud, D.3    Dunnette, S.4    Gleich, G.J.5    Lichtenstein, L.M.6
  • 63
    • 0030950378 scopus 로고    scopus 로고
    • The effect of fluticasone propionate aqueous nasal spray on eosinophils and cytokines in nasal secretions of patients with ragweed allergic rhinitis
    • Alvarado-Valdes CA, Blomgren J, Weiler D, Gleich GJ, Reed CE, Field EA, et al., The effect of fluticasone propionate aqueous nasal spray on eosinophils and cytokines in nasal secretions of patients with ragweed allergic rhinitis. Clin Ther 1997; 19: 273-281.
    • (1997) Clin Ther , vol.19 , pp. 273-281
    • Alvarado-Valdes, C.A.1    Blomgren, J.2    Weiler, D.3    Gleich, G.J.4    Reed, C.E.5    Field, E.A.6
  • 66
    • 77957357809 scopus 로고    scopus 로고
    • Expression of genes that encode the annexin-1 and galectin-1 proteins in nasal polyposis and their modulation by glucocorticoid
    • Fernandes AM, Babeto E, Rahal P, Provazzi PJ, Hidalgo CA, Anselmo-Lima WT,. Expression of genes that encode the annexin-1 and galectin-1 proteins in nasal polyposis and their modulation by glucocorticoid. Braz J Otorhinolaryngol 2010; 76: 213-218.
    • (2010) Braz J Otorhinolaryngol , vol.76 , pp. 213-218
    • Fernandes, A.M.1    Babeto, E.2    Rahal, P.3    Provazzi, P.J.4    Hidalgo, C.A.5    Anselmo-Lima, W.T.6
  • 67
    • 0038241921 scopus 로고    scopus 로고
    • Expression patterns of galectin-1 and galectin-3 in nasal polyps and middle and inferior turbinates in relation to growth regulation and immunosuppression
    • Delbrouck C, Gabius HJ, Kaltner H, Decaestecker C, Kiss R, Hassid S,. Expression patterns of galectin-1 and galectin-3 in nasal polyps and middle and inferior turbinates in relation to growth regulation and immunosuppression. Arch Otolaryngol Head Neck Surg 2003; 129: 665-669.
    • (2003) Arch Otolaryngol Head Neck Surg , vol.129 , pp. 665-669
    • Delbrouck, C.1    Gabius, H.J.2    Kaltner, H.3    Decaestecker, C.4    Kiss, R.5    Hassid, S.6
  • 68
    • 52049109854 scopus 로고    scopus 로고
    • Rosiglitazone attenuates allergic inflammation and inhibits expression of galectin-3 in a mouse model of allergic rhinitis
    • Han JL, Ding RY, Zhao L, Ren Z, Jiang XJ,. Rosiglitazone attenuates allergic inflammation and inhibits expression of galectin-3 in a mouse model of allergic rhinitis. J Int Med Res 2008; 36: 830-836.
    • (2008) J Int Med Res , vol.36 , pp. 830-836
    • Han, J.L.1    Ding, R.Y.2    Zhao, L.3    Ren, Z.4    Jiang, X.J.5
  • 70
    • 48449106952 scopus 로고    scopus 로고
    • Differentiated S100A7 expression in infected tonsils and tonsils from allergic individuals
    • Bryborn M, Mansson A, Cardell LO, Adner M,. Differentiated S100A7 expression in infected tonsils and tonsils from allergic individuals. FEMS Immunol Med Microbiol 2008; 53: 413-420.
    • (2008) FEMS Immunol Med Microbiol , vol.53 , pp. 413-420
    • Bryborn, M.1    Mansson, A.2    Cardell, L.O.3    Adner, M.4
  • 73
    • 84858775590 scopus 로고    scopus 로고
    • Lung natural helper cells are a critical source of Th2 cell-type cytokines in protease allergen-induced airway inflammation
    • Halim TY, Krauss RH, Sun AC, Takei F,. Lung natural helper cells are a critical source of Th2 cell-type cytokines in protease allergen-induced airway inflammation. Immunity 2012; 36: 451-463.
    • (2012) Immunity , vol.36 , pp. 451-463
    • Halim, T.Y.1    Krauss, R.H.2    Sun, A.C.3    Takei, F.4
  • 74
    • 80054889051 scopus 로고    scopus 로고
    • Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161
    • Mjosberg JM, Trifari S, Crellin NK, Peters CP, van Drunen CM, Piet B, et al., Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161. Nat Immunol 2011; 12: 1055-1062.
    • (2011) Nat Immunol , vol.12 , pp. 1055-1062
    • Mjosberg, J.M.1    Trifari, S.2    Crellin, N.K.3    Peters, C.P.4    Van Drunen, C.M.5    Piet, B.6
  • 75
    • 84905859405 scopus 로고    scopus 로고
    • Association between group 2 innate lymphoid cells enrichment, nasal polyps and allergy in chronic rhinosinusitis
    • Miljkovic D, Bassiouni A, Cooksley C, Ou J, Hauben E, Wormald PJ, et al., Association between group 2 innate lymphoid cells enrichment, nasal polyps and allergy in chronic rhinosinusitis. Allergy 2014; 69: 1154-1161.
    • (2014) Allergy , vol.69 , pp. 1154-1161
    • Miljkovic, D.1    Bassiouni, A.2    Cooksley, C.3    Ou, J.4    Hauben, E.5    Wormald, P.J.6
  • 76
    • 84923082670 scopus 로고    scopus 로고
    • Group 2 innate lymphoid cells (ILC2s) are increased in chronic rhinosinusitis with nasal polyps or eosinophilia
    • Ho J, Bailey M, Zaunders J, Mrad N, Sacks R, Sewell W, et al., Group 2 innate lymphoid cells (ILC2s) are increased in chronic rhinosinusitis with nasal polyps or eosinophilia. Clin Exp Allergy 2015; 45: 394-403.
    • (2015) Clin Exp Allergy , vol.45 , pp. 394-403
    • Ho, J.1    Bailey, M.2    Zaunders, J.3    Mrad, N.4    Sacks, R.5    Sewell, W.6
  • 77
    • 84907694433 scopus 로고    scopus 로고
    • Increased ILC2s in the eosinophilic nasal polyp endotype are associated with corticosteroid responsiveness
    • Walford HH, Lund SJ, Baum RE, White AA, Bergeron CM, Husseman J, et al., Increased ILC2s in the eosinophilic nasal polyp endotype are associated with corticosteroid responsiveness. Clin Immunol 2014; 155: 126-135.
    • (2014) Clin Immunol , vol.155 , pp. 126-135
    • Walford, H.H.1    Lund, S.J.2    Baum, R.E.3    White, A.A.4    Bergeron, C.M.5    Husseman, J.6
  • 78
    • 77950879453 scopus 로고    scopus 로고
    • Treatment-recalcitrant chronic rhinosinusitis with polyps is associated with altered epithelial cell expression of interleukin-33
    • Reh DD, Wang Y, Ramanathan M Jr, Lane AP,. Treatment-recalcitrant chronic rhinosinusitis with polyps is associated with altered epithelial cell expression of interleukin-33. Am J Rhinol Allergy 2010; 24: 105-109.
    • (2010) Am J Rhinol Allergy , vol.24 , pp. 105-109
    • Reh, D.D.1    Wang, Y.2    Ramanathan, M.3    Lane, A.P.4
  • 79
    • 79955040263 scopus 로고    scopus 로고
    • The danger signal, extracellular ATP, is a sensor for an airborne allergen and triggers IL-33 release and innate Th2-type responses
    • Kouzaki H, Iijima K, Kobayashi T, O'Grady SM, Kita H,. The danger signal, extracellular ATP, is a sensor for an airborne allergen and triggers IL-33 release and innate Th2-type responses. J Immunol 2011; 186: 4375-4387.
    • (2011) J Immunol , vol.186 , pp. 4375-4387
    • Kouzaki, H.1    Iijima, K.2    Kobayashi, T.3    O'Grady, S.M.4    Kita, H.5
  • 80
    • 84882625503 scopus 로고    scopus 로고
    • IL-33-responsive innate lymphoid cells are an important source of IL-13 in chronic rhinosinusitis with nasal polyps
    • Shaw JL, Fakhri S, Citardi MJ, Porter PC, Corry DB, Kheradmand F, et al., IL-33-responsive innate lymphoid cells are an important source of IL-13 in chronic rhinosinusitis with nasal polyps. Am J Respir Crit Care Med 2013; 188: 432-439.
    • (2013) Am J Respir Crit Care Med , vol.188 , pp. 432-439
    • Shaw, J.L.1    Fakhri, S.2    Citardi, M.J.3    Porter, P.C.4    Corry, D.B.5    Kheradmand, F.6
  • 81
    • 84906822605 scopus 로고    scopus 로고
    • Enhanced innate type 2 immune response in peripheral blood from patients with asthma
    • Bartemes KR, Kephart GM, Fox SJ, Kita H,. Enhanced innate type 2 immune response in peripheral blood from patients with asthma. J Allergy Clin Immunol 2014; 134: 671-678.
    • (2014) J Allergy Clin Immunol , vol.134 , pp. 671-678
    • Bartemes, K.R.1    Kephart, G.M.2    Fox, S.J.3    Kita, H.4
  • 82
    • 84930948511 scopus 로고    scopus 로고
    • Airway epithelium interactions with aeroallergens: Role of secreted cytokines and chemokines in innate immunity
    • Gandhi VD, Vliagoftis H,. Airway epithelium interactions with aeroallergens: role of secreted cytokines and chemokines in innate immunity. Front Immunol 2015; 6: 147.
    • (2015) Front Immunol , vol.6 , pp. 147
    • Gandhi, V.D.1    Vliagoftis, H.2
  • 83
    • 84938199992 scopus 로고    scopus 로고
    • Th2 cytokines impair innate immune responses to rhinovirus in respiratory epithelial cells
    • Contoli M, Ito K, Padovani A, Poletti D, Marku B, Edwards MR, et al., Th2 cytokines impair innate immune responses to rhinovirus in respiratory epithelial cells. Allergy 2015; 70: 910-920.
    • (2015) Allergy , vol.70 , pp. 910-920
    • Contoli, M.1    Ito, K.2    Padovani, A.3    Poletti, D.4    Marku, B.5    Edwards, M.R.6
  • 85
    • 77954336914 scopus 로고    scopus 로고
    • Staphylococcus aureus enterotoxin B augments granulocyte migration and survival via airway epithelial cell activation
    • Huvenne W, Callebaut I, Reekmans K, Hens G, Bobic S, Jorissen M, et al., Staphylococcus aureus enterotoxin B augments granulocyte migration and survival via airway epithelial cell activation. Allergy 2010; 65: 1013-1020.
    • (2010) Allergy , vol.65 , pp. 1013-1020
    • Huvenne, W.1    Callebaut, I.2    Reekmans, K.3    Hens, G.4    Bobic, S.5    Jorissen, M.6
  • 87
    • 79955602309 scopus 로고    scopus 로고
    • Eosinophil and neutrophil extracellular DNA traps in human allergic asthmatic airways
    • Dworski R, Simon HU, Hoskins A, Yousefi S,. Eosinophil and neutrophil extracellular DNA traps in human allergic asthmatic airways. J Allergy Clin Immunol 2011; 127: 1260-1266.
    • (2011) J Allergy Clin Immunol , vol.127 , pp. 1260-1266
    • Dworski, R.1    Simon, H.U.2    Hoskins, A.3    Yousefi, S.4
  • 88
    • 51349135381 scopus 로고    scopus 로고
    • Catapult-like release of mitochondrial DNA by eosinophils contributes to antibacterial defense
    • Yousefi S, Gold JA, Andina N, Lee JJ, Kelly AM, Kozlowski E, et al., Catapult-like release of mitochondrial DNA by eosinophils contributes to antibacterial defense. Nat Med 2008; 14: 949-953.
    • (2008) Nat Med , vol.14 , pp. 949-953
    • Yousefi, S.1    Gold, J.A.2    Andina, N.3    Lee, J.J.4    Kelly, A.M.5    Kozlowski, E.6
  • 89
    • 84869865730 scopus 로고    scopus 로고
    • Eosinophil extracellular DNA traps: Molecular mechanisms and potential roles in disease
    • Yousefi S, Simon D, Simon HU,. Eosinophil extracellular DNA traps: molecular mechanisms and potential roles in disease. Curr Opin Immunol 2012; 24: 736-739.
    • (2012) Curr Opin Immunol , vol.24 , pp. 736-739
    • Yousefi, S.1    Simon, D.2    Simon, H.U.3
  • 90
    • 84925764661 scopus 로고    scopus 로고
    • Active eosinophilic esophagitis is characterized by epithelial barrier defects and eosinophil extracellular trap formation
    • Simon D, Radonjic-Hösli S, Straumann A, Yousefi S, Simon HU, et al., Active eosinophilic esophagitis is characterized by epithelial barrier defects and eosinophil extracellular trap formation. Allergy 2015; 70: 443-452.
    • (2015) Allergy , vol.70 , pp. 443-452
    • Simon, D.1    Radonjic-Hösli, S.2    Straumann, A.3    Yousefi, S.4    Simon, H.U.5
  • 91
    • 84887782138 scopus 로고    scopus 로고
    • Staphylococcus aureus degrades neutrophil extracellular traps to promote immune cell death
    • Thammavongsa V, Missiakas DM, Schneewind O,. Staphylococcus aureus degrades neutrophil extracellular traps to promote immune cell death. Science 2013; 342: 863-866.
    • (2013) Science , vol.342 , pp. 863-866
    • Thammavongsa, V.1    Missiakas, D.M.2    Schneewind, O.3
  • 93
    • 84865032686 scopus 로고    scopus 로고
    • Thymic stromal lymphopoietin stimulates the formation of eosinophil extracellular traps
    • Morshed M, Yousefi S, Stöckle C, Simon HU, Simon D,. Thymic stromal lymphopoietin stimulates the formation of eosinophil extracellular traps. Allergy 2012; 67: 1127-1137.
    • (2012) Allergy , vol.67 , pp. 1127-1137
    • Morshed, M.1    Yousefi, S.2    Stöckle, C.3    Simon, H.U.4    Simon, D.5
  • 94
    • 84900531783 scopus 로고    scopus 로고
    • The importance of local eosinophilia in the surgical outcome of chronic rhinosinusitis: A 3-year prospective observational study
    • Vlaminck S, Vauterin T, Hellings PW, Jorissen M, Acke F, Van Cauwenberge P, et al., The importance of local eosinophilia in the surgical outcome of chronic rhinosinusitis: a 3-year prospective observational study. Am J Rhinol Allergy 2014; 28: 260-264.
    • (2014) Am J Rhinol Allergy , vol.28 , pp. 260-264
    • Vlaminck, S.1    Vauterin, T.2    Hellings, P.W.3    Jorissen, M.4    Acke, F.5    Van Cauwenberge, P.6
  • 95
    • 71449127101 scopus 로고    scopus 로고
    • Modulation of gut-associated lymphoid tissue functions with genetically modified Lactococcus lactis
    • Rottiers P, De Smedt T, Steidler L,. Modulation of gut-associated lymphoid tissue functions with genetically modified Lactococcus lactis. Int Rev Immunol 2009; 28: 465-486.
    • (2009) Int Rev Immunol , vol.28 , pp. 465-486
    • Rottiers, P.1    De Smedt, T.2    Steidler, L.3
  • 96
    • 80052555956 scopus 로고    scopus 로고
    • Microbiological and molecular assessment of bacteriophage ISP for the control of Staphylococcus aureus
    • Vandersteegen K, Mattheus W, Ceyssens PJ, Bilocq F, De Vos D, Pirnay JP, et al., Microbiological and molecular assessment of bacteriophage ISP for the control of Staphylococcus aureus. PLoS One 2011; 6: e24418.
    • (2011) PLoS One , vol.6 , pp. e24418
    • Vandersteegen, K.1    Mattheus, W.2    Ceyssens, P.J.3    Bilocq, F.4    De Vos, D.5    Pirnay, J.P.6
  • 97
    • 19744361985 scopus 로고    scopus 로고
    • Antimicrobial activity of murine lung cells against Staphylococcus aureus is increased in vitro and in vivo after elafin gene transfer
    • McMichael JW, Maxwell AI, Hayashi K, Taylor K, Wallace WA, Govan JR, et al., Antimicrobial activity of murine lung cells against Staphylococcus aureus is increased in vitro and in vivo after elafin gene transfer. Infect Immun 2005; 73: 3.
    • (2005) Infect Immun , vol.73 , pp. 3
    • McMichael, J.W.1    Maxwell, A.I.2    Hayashi, K.3    Taylor, K.4    Wallace, W.A.5    Govan, J.R.6
  • 98
    • 84896543863 scopus 로고    scopus 로고
    • SantosN. Antimicrobial protein rBPI21-induced surface changes on Gram-negative and Gram-positive bacteria
    • Domingues M, Silva P, Franquelim H, Carvalho F, Castanho M,. SantosN. Antimicrobial protein rBPI21-induced surface changes on Gram-negative and Gram-positive bacteria. Nanomedicine 2014; 10: 543-551.
    • (2014) Nanomedicine , vol.10 , pp. 543-551
    • Domingues, M.1    Silva, P.2    Franquelim, H.3    Carvalho, F.4    Castanho, M.5
  • 99
    • 84893728733 scopus 로고    scopus 로고
    • Staphylococcus aureus toxins-their functions and genetics
    • Grumann D, Nubel U, Bröker MK,. Staphylococcus aureus toxins-their functions and genetics. Infect Genet Evol 2014; 21: 583-592.
    • (2014) Infect Genet Evol , vol.21 , pp. 583-592
    • Grumann, D.1    Nubel, U.2    Bröker, M.K.3
  • 100
    • 1242272034 scopus 로고    scopus 로고
    • Design of chimeric receptor mimics with different TcR Vbeta isoforms. Type-specific inhibition of superantigen pathogenesis
    • Hong-Geller E, Möllhoff M, Shiflett P, Gupta G,. Design of chimeric receptor mimics with different TcR Vbeta isoforms. Type-specific inhibition of superantigen pathogenesis. J Biol Chem 2004; 279: 5676-5684.
    • (2004) J Biol Chem , vol.279 , pp. 5676-5684
    • Hong-Geller, E.1    Möllhoff, M.2    Shiflett, P.3    Gupta, G.4
  • 101
    • 0031921886 scopus 로고    scopus 로고
    • Assessment by nasal biopsy of long-term use of mometasone furoate aqueous nasal spray (Nasonex) in the treatment of perennial rhinitis
    • Minshall E, Ghaffar O, Cameron L, O'Brien F, Quinn H, Rowe-Jones J, et al., Assessment by nasal biopsy of long-term use of mometasone furoate aqueous nasal spray (Nasonex) in the treatment of perennial rhinitis. Otolaryngol Head Neck Surg 1998; 118: 648-654.
    • (1998) Otolaryngol Head Neck Surg , vol.118 , pp. 648-654
    • Minshall, E.1    Ghaffar, O.2    Cameron, L.3    O'Brien, F.4    Quinn, H.5    Rowe-Jones, J.6
  • 102
    • 77953359952 scopus 로고    scopus 로고
    • AG013, a mouth rinse formulation of Lactococcus lactis secreting human Trefoil Factor 1, provides a safe and efficacious therapy tool for treating oral mucositis
    • Caluwaerts S, Vandenbroucke K, Steidler L, Neirynck S, Vanhoenacker P, Corveleyn S, et al., AG013, a mouth rinse formulation of Lactococcus lactis secreting human Trefoil Factor 1, provides a safe and efficacious therapy tool for treating oral mucositis. Oral Oncol 2010; 46: 564-570.
    • (2010) Oral Oncol , vol.46 , pp. 564-570
    • Caluwaerts, S.1    Vandenbroucke, K.2    Steidler, L.3    Neirynck, S.4    Vanhoenacker, P.5    Corveleyn, S.6
  • 103
    • 79951956167 scopus 로고    scopus 로고
    • TLR agonist mediated suppression of allergic responses is associated with increased innate inflammation in the airways
    • Duechs M, Hahn C, Benediktus E, Werner-Klein M, Braun A, Hoymann H, et al., TLR agonist mediated suppression of allergic responses is associated with increased innate inflammation in the airways. Pulm Pharmacol Ther 2011; 24: 203-214.
    • (2011) Pulm Pharmacol Ther , vol.24 , pp. 203-214
    • Duechs, M.1    Hahn, C.2    Benediktus, E.3    Werner-Klein, M.4    Braun, A.5    Hoymann, H.6
  • 105
    • 80055080497 scopus 로고    scopus 로고
    • Mepolizumab, a humanised anti-IL-5 monoclonal antibody, as treatment option for severe nasal polyposis
    • Gevaert P, Van Bruaene N, Cattaert T, Van Steen K, Van Zele T, Acke F, et al., Mepolizumab, a humanised anti-IL-5 monoclonal antibody, as treatment option for severe nasal polyposis. J Allergy Clin Immunol 2011; 128: 989-995.
    • (2011) J Allergy Clin Immunol , vol.128 , pp. 989-995
    • Gevaert, P.1    Van Bruaene, N.2    Cattaert, T.3    Van Steen, K.4    Van Zele, T.5    Acke, F.6
  • 108
    • 84871716411 scopus 로고    scopus 로고
    • Omalizumab is effective in allergic and non-allergic patients with nasal polyposis and co-morbid asthma
    • Gevaert P, Calus L, Van Zele T, Blomme K, De Ruyck N, Bauters W, et al., Omalizumab is effective in allergic and non-allergic patients with nasal polyposis and co-morbid asthma. J Allergy Clin Immunol 2013; 131: 110-116.
    • (2013) J Allergy Clin Immunol , vol.131 , pp. 110-116
    • Gevaert, P.1    Calus, L.2    Van Zele, T.3    Blomme, K.4    De Ruyck, N.5    Bauters, W.6


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