Toll-like receptor 2, 3, 4, 5 ligands and interleukin-4 synergistically induce TARC production in nasal polyp fibroblasts

Auris Nasus Larynx

Volumn 35, Issue 4, 2008, Pages 515-520

  Nonaka, Manabu ^a   Ogihara, Nozomu ^a   Fukumoto, Akira ^a   Sakanushi, Atsuko ^a   Pawankar, Ruby ^a   Yagi, Toshiaki ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

Author keywords

Fibroblasts; Nasal polyp; TARC; TLR ligand

Indexed keywords

INTERLEUKIN 4; THYMUS AND ACTIVATION REGULATED CHEMOKINE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5;

ADULT; ARTICLE; CHRONIC SINUSITIS; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBROBLAST; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; NOSE POLYP; PROTEIN EXPRESSION; PROTEIN SECRETION; REAL TIME POLYMERASE CHAIN REACTION; TH2 CELL;

ADULT; BIOPSY; CELL LINE; CHEMOKINE CCL17; FEMALE; FIBROBLASTS; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-4; MALE; MIDDLE AGED; NASAL POLYPS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TOLL-LIKE RECEPTOR 1; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 3; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTOR 5;

EID: 54049104011     PISSN: 03858146     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.anl.2008.02.001     Document Type: Article

References (31)

1. Imai T., Yoshida T., Baba M., Nishimura M., Kakizaki M., and Yoshie O. Molecular cloning of a novel T cell-directed CC chemokine expressed in thymus by signal sequence trap using Epstein-Barr virus vector. J Biol Chem 271 (1996) 21514-21521
2. Imai T., Nagira M., Takagi S., Kakizaki M., Nishimura M., Wang J., et al. Selective recruitment of CCR4-bearing Th2 cells toward antigen-presenting cells by the CC chemokines thymus and activation-regulated chemokine and macrophage-derived chemokine. Int Immunol 11 (1999) 81-88
3. Romagnani S. Regulation of the development of type 2 T-helper cells in allergy. Curr Opin Immunol 6 (1994) 838-846
4. Elhini A., Abdelwahab S., and Ikeda K. Th1 and Th2 cell population in chronic ethmoidal rhinosinusitis: a chemokine receptor assay. Laryngoscope 115 (2005) 1272-1277
5. Teran L.M., Mochizuki M., Bartels J., Valencia E.L., Nakajima T., Hirai K., et al. Th1- and Th2-type cytokines regulate the expression and production of eotaxin and RANTES by human lung fibroblasts. Am J Respir Cell Mol Biol 20 (1999) 777-786
6. Smith R.S., Smith T.J., Blieden T.M., and Phipps R.P. Fibroblasts as sentinel cells. Synthesis of chemokines and regulation of inflammation. Am J Pathol 151 (1997) 317-322
7. Buckley C.D., Pilling D., Lord J.M., Akbar A.N., Scheel-Toellner D., and Salmon M. Fibroblasts regulate the switch from acute resolving to chronic persistent inflammation. Trends Immunol 22 (2001) 199-204
8. Sappino A.P., Schurch W., and Gabbiani G. Differentiation repertoire of fibroblastic cells: expression of cytoskeletal proteins as marker of phenotypic modulations. Lab Invest 63 (1990) 144-161
9. Schmitt-Graff A., Desmouliere A., and Gabbiani G. Heterogeneity of myofibroblast phenotype features: an example of fibroblastic cell plasticity. Virchows Arch 425 (1994) 3-24
10. Xing X., Jordana M., Braciak T., Ohtoshi T., and Gauldie J. Lipopolysaccharide induces expression of granulocyte/macrophage colony-stimulating factor, interleukin-8, and interleukin-6 in human nasal, but not lung, fibroblasts: evidence for heterogeneity within the respiratory tract. Am J Respir Cell Mol Biol 9 (1993) 255-263
11. Nonaka M., Pawankar R., Saji F., and Yagi T. Distinct expression of RANTES and GM-CSF by lipopolysaccharide in human nasal fibroblasts but not in other airway fibroblasts. Int Arch Allergy Immunol 119 (1999) 314-321
12. Vancheri C., Ohtoshi T., Cox G., Xaubet A., Abrams J.S., Gauldie J., et al. Neutrophilic differentiation induced by human upper airway fibroblast-derived granulocyte/macrophage colony-stimulating factor (GM-CSF). Am J Respir Cell Mol Biol 4 (1991) 11-17
13. Akira S. Toll-like receptor signaling. J Biol Chem 278 (2003) 38105-38108
14. Zlotnik A., and Yoshie O. Chemokines: a new classification system and their role in immunity. Immunity 12 (2000) 121-127
15. Wuyts A., Proost P., and Van Damme J. Interleukin-8 and other CXC chemokines. In: Thomson A.W. (Ed). The Cytokine Handbook. third ed. (1998), Academic Press, San Diego, CA 271-311
16. Suzuki H., Takahashi Y., Wataya H., Ikeda K., Nakabayashi S., Shimomura A., et al. Mechanism of neutrophils recruitment induced by IL-8 in chronic sinusitis. J Allergy Clin Immunol 98 (1996) 659-670
17. Kennedy D.W., Zinreich S.J., Rosenbaum A.E., and John M.E. Functional endoscopic sinus surgery. Arch Otolaryngol 111 (1985) 576-582
18. Mitani T., Okazaki N., Okuno Y., Maeda N., Kuno H., DeMaria T.F., et al. Endotoxin in maxillary sinus effusion from patients with chronic sinusitis [in Japanese]. Nihon Jibiinnkouka Kansenshou Kenkyuukai Kaishi 3 (1985) 98-101
19. Takahashi N., Yamada T., Narita N., and Fujieda S. Double-stranded RNA induces production of RANTES and IL-8 by human nasal fibroblasts. Clin Immunol 118 (2006) 51-58
20. Hamilos D.L., Leung D.Y.M., Wood R., Cunningham L., Bean D.K., Yasruel Z., et al. Evidence for distinct cytokine expression in allergic versus nonallergic chronic sinusitis. J Allergy Clin Immunol 96 (1995) 537-544
21. Yoneyama H., Harada A., Imai T., Baba M., Yoshie O., Zhang Y., et al. Pivotal role of TARC, a CC chemokine, in bacteria-induced fulminant hepatic failure in mice. J Clin Invest 102 (1998) 1933-1941
22. + T cells. Eur J Immunol 29 (1999) 2684-2694
23. Terada N., Nomura T., Kim W.J., Otsuka Y., Takahashi R., Kishi H., et al. Expression of C-C chemokine TARC in human nasal mucosa and its regulation by cytokines. Clin Exp Allergy 31 (2001) 1923-1931
24. Sekiya T., Miyamasu M., Imanishi M., Yamada H., Nakajima T., Yamaguchi M., et al. Inducible expression of a Th2-type CC chemokine thymus- and activation-regulated chemokine by human bronchial epithelial cells. J Immunol 165 (2000) 2205-2213
25. Cecilia B., Eckmann L., and Broide D.H. Kagnoff MF: regulated production of the T helper 2-type T-cell chemoattractant TARC by human bronchial epithelial cells in vitro and in human lung xenografts. Am J Respir Cell Mol Biol 24 (2001) 382-389
26. Wirnsberger G., Hebenstreit D., Posselt G., Horejs-Hoeck J., and Duschl A. IL-4 induces expression of TARC/CCL17 via two STAT6 binding sites. Eur J Immunol 36 (2006) 1882-1891
27. Matsukura S., Stellato C., Plitt J.R., Bickel C., Miura K., Georas S.N., et al. Activation of eotaxin gene transcription by NF-κB and STAT6 in human airway epithelial cells. J Immunol 163 (1999) 6876-6883
28. Takeuchi O., Kawai T., Muhlradt P.F., Morr M., Radolf J.D., Zychlinsky A., et al. Discrimination of bacterial lipoproteins by Toll-like receptor 6. Int Immunol 13 (2001) 933-940
29. Akira S. Toll receptor families: structure and function. Semin Immunol 16 (2004) 1-2
30. Hemmi H., Takeuchi O., Kawai T., Kaisho T., Sato S., Sanjo H., et al. A Toll-like receptor recognizes bacterial DNA. Nature 408 (2000) 740-745
31. Heil F., Hemmi H., Hochrein H., Ampenberger F., Kirschning C., Akira S., et al. Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8. Science 303 (2004) 1526-1531