Design of chimeric receptor mimics with different TcRVβ isoforms: Type-specific inhibition of superantigen pathogenesis

Journal of Biological Chemistry

Volumn 279, Issue 7, 2004, Pages 5676-5684

  Hong Geller, Elizabeth ^a   Möllhoff, Margit ^a   Shiflett, Patrick R ^a   Gupta, Goutam ^a  

^a LOS ALAMOS NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; CELLS; PROTEINS; TOXIC MATERIALS;

ENTEROTOXINS; TOXIC SHOCK SYNDROME;

BIOCHEMISTRY;

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 2; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; STAPHYLOCOCCUS ENTEROTOXIN; SUPERANTIGEN; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR BETA CHAIN; TOXIC SHOCK SYNDROME TOXIN 1; TUMOR NECROSIS FACTOR ALPHA;

ANTIGEN BINDING; ANTIGEN SPECIFICITY; ARTICLE; BINDING AFFINITY; CHIMERA; CYTOKINE RELEASE; FOOD POISONING; HUMAN; HUMAN CELL; IMMUNOCOMPETENT CELL; IMMUNOSTIMULATION; LYMPHOCYTE PROLIFERATION; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION; T LYMPHOCYTE; TOXIC SHOCK SYNDROME;

AMINO ACID SEQUENCE; ANTIGENS; CELL DIVISION; CELL LINE; CLONING, MOLECULAR; ENTEROTOXINS; HUMANS; INTERLEUKIN-2; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; RECOMBINANT FUSION PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; STAPHYLOCOCCUS AUREUS; T-LYMPHOCYTES; TEMPERATURE; TIME FACTORS;

POSIBACTERIA; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS;

EID: 1242272034     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M309388200     Document Type: Article

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