Melatonin protects against chronic intermittent hypoxia-induced cardiac hypertrophy by modulating autophagy through the 5′ adenosine monophosphate-activated protein kinase pathway

Biochemical and Biophysical Research Communications

Volumn 464, Issue 4, 2015, Pages 975-981

  Xie, Sheng ^a   Deng, Yan ^a   Pan, Yue Ying ^a   Wang, Zhi Hua ^a   Ren, Jie ^a   Guo, Xue Ling ^a   Yuan, Xiao ^a   Shang, Jin ^a   Liu, Hui Guo ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Adenosine monophosphate activated protein kinase; Apoptosis; Autophagy; Cardiac hypertrophy; Chronic intermittent hypoxia

Indexed keywords

5' ADENOSINE MONOPHOSPHATE ACTIVATED PROTEIN KINASE; ADENYLATE KINASE; ATRIAL NATRIURETIC FACTOR; BECLIN 1; MELATONIN; PROTEIN KINASE; PROTEIN P62; UNCLASSIFIED DRUG; CARDIOTONIC AGENT; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PROTEIN KINASE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CHRONIC INTERMITTENT HYPOXIA; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; HEART MUSCLE; HEART MUSCLE CELL; HEART PROTECTION; HEART VENTRICLE HYPERTROPHY; IN VITRO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RAT; TRANSMISSION ELECTRON MICROSCOPY; TUNEL ASSAY; WESTERN BLOTTING; ANIMAL; ANOXIA; ANTAGONISTS AND INHIBITORS; CARDIOMEGALY; CELL LINE; CHRONIC DISEASE; COMPLICATION; DISEASE MODEL; DRUG EFFECTS; ENZYMOLOGY; HUMAN; METABOLISM; PATHOLOGY; PHAGOSOME; PHYSIOLOGY; SIGNAL TRANSDUCTION; SLEEP DISORDERED BREATHING; SPRAGUE DAWLEY RAT;

RATTUS;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ANOXIA; AUTOPHAGY; CARDIOMEGALY; CARDIOTONIC AGENTS; CELL LINE; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; ENZYME ACTIVATION; HUMANS; MALE; MELATONIN; MICROSCOPY, ELECTRON, TRANSMISSION; MYOCYTES, CARDIAC; PHAGOSOMES; PROTEIN KINASE INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SLEEP APNEA, OBSTRUCTIVE;

EID: 84940462464     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.06.149     Document Type: Article

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