Melatonin inhibits adipogenesis and enhances osteogenesis of human mesenchymal stem cells by suppressing PPARγ expression and enhancing Runx2 expression

Journal of Pineal Research

Volumn 49, Issue 4, 2010, Pages 364-372

  Zhang, Liangming ^a   Su, Peiqiang ^a   Xu, Caixia ^b   Chen, Changhua ^a   Liang, Anjing ^a   Du, Kaili ^a   Peng, Yan ^a   Huang, Dongsheng ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b SOUTH CHINA UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

adipogenesis; human mesenchymal stem cells; melatonin; osteogenesis; peroxisome proliferator activated receptor gamma; Runx2

Indexed keywords

ADIPOCYTE PROTEIN 2; ADIPONECTIN; ALKALINE PHOSPHATASE; BETA1 INTEGRIN; CD44V ANTIGEN; CELL PROTEIN; ENDOGLIN; LEPTIN; LIPOPROTEIN LIPASE; MELATONIN; OSTEOCALCIN; OSTEOPONTIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG;

ADIPOCYTE; ADIPOGENESIS; ARTICLE; BONE DEVELOPMENT; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; DOSE RESPONSE; ENZYME REPRESSION; HUMAN; HUMAN CELL; MESENCHYMAL STEM CELL; NUCLEOTIDE SEQUENCE; OSTEOBLAST; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADIPOGENESIS; ALKALINE PHOSPHATASE; ANALYSIS OF VARIANCE; BIOLOGICAL MARKERS; BONE MARROW CELLS; CELL PROLIFERATION; CELLS, CULTURED; CORE BINDING FACTOR ALPHA 1 SUBUNIT; HISTOCYTOCHEMISTRY; HUMANS; MELATONIN; MESENCHYMAL STEM CELLS; OSTEOGENESIS; PPAR GAMMA; TRYPTAMINES;

EID: 78349247846     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/j.1600-079X.2010.00803.x     Document Type: Article

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