Curcumin upregulates Nrf2 nuclear translocation and protects rat hepatic stellate cells against oxidative stress

Molecular Medicine Reports

Volumn 13, Issue 2, 2016, Pages 1717-1724

  Liu, Zhenxiong ^a   Dou, Weijia ^a   Zheng, Yuanyuan ^b   Wen, Qinsheng ^a   Qin, Ming ^a   Wang, Xuxia ^a   Tang, Hua ^a   Zhang, Rong ^a   Lv, Dandan ^a   Wang, Jingjie ^a   Zhao, Shuguang ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b Department of Gastroenterology   (China)

Author keywords

Curcumin; Fibrosis; Hepatic stellate cell; Nuclear factor erythroid 2 related factor; Oxidative stress

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ANTIOXIDANT; COLLAGEN TYPE 4; CURCUMIN; CYTOPROTECTIVE AGENT; DESMIN; GLUCOSE OXIDASE; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; HYALURONIC ACID; LAMININ; LIVER PROTECTIVE AGENT; MALONALDEHYDE; PROCOLLAGEN; PROCOLLAGEN III; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; ACTIN; PROTECTIVE AGENT; SMOOTH MUSCLE ACTIN, RAT;

ANIMAL CELL; ARTICLE; CELL ACTIVATION; CELL NUCLEUS; CELL PROTECTION; CONTROLLED STUDY; CYTOPLASM; DRUG MECHANISM; EXTRACELLULAR MATRIX; FLOW CYTOMETRY; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; INTERMEDIATE FILAMENT; LIPID PEROXIDATION; LIVER PROTECTION; MYOFIBROBLAST; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RADIOIMMUNOASSAY; RAT; STELLATE CELL; UPREGULATION; WESTERN BLOTTING; ANIMAL; CELL LINE; DRUG EFFECTS; HEPATIC STELLATE CELL; METABOLISM; PATHOLOGY; PROTEIN TRANSPORT;

ACTINS; ANIMALS; CELL LINE; CELL NUCLEUS; CURCUMIN; CYTOPROTECTION; DESMIN; EXTRACELLULAR MATRIX; GLUCOSE OXIDASE; HEPATIC STELLATE CELLS; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PROTECTIVE AGENTS; PROTEIN TRANSPORT; RATS; REACTIVE OXYGEN SPECIES; UP-REGULATION;

EID: 84956962439     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.4690     Document Type: Article

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