Hepatic wound repair

Fibrogenesis and Tissue Repair

Volumn 2, Issue 1, 2009, Pages

  Parola, Maurizio ^a   Pinzani, Massimo ^b  

^a UNIVERSITY OF TURIN   (Italy)

^b UNIVERSITY OF FLORENCE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 80054730582     PISSN: None     EISSN: 17551536     Source Type: Journal    
DOI: 10.1186/1755-1536-2-4     Document Type: Review

References (28)

1. Friedman SL. Mechanisms of disease: mechanisms of hepatic fibrosis and therapeutic implications. Nat Clin Pract Gastroenterol Hepatol 2004, 1:98-105. 10.1038/ncpgasthep0055, 16265071.
2. Pinzani M, Rombouts K. Liver fibrosis - from the bench to clinical targets. Dig Liver Dis 2004, 36:231-242. 10.1016/j.dld.2004.01.003, 15115333.
3. Friedman SL. Mechanisms of hepatic fibrogenesis. Gastroenterology 2008, 134:1655-1669. 10.1053/j.gastro.2008.03.003, 2888539, 18471545.
4. Parola M, Marra F, Pinzani M. Myofibroblast-like cells and liver fibrogenesis: emerging concepts in a rapidly moving scenario. Mol Asp Med 2008, 29:58-66.
5. Cassiman D, Libbrecht L, Desmet V, Denef C, Roskams T. Hepatic stellate cell/myofibroblast subpopulations in fibrotic human and rat livers. J Hepatol 2002, 36:200-209. 10.1016/S0168-8278(01)00260-4, 11830331.
6. Friedman SL. Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver. Physiol Rev 2008, 88:125-172. 10.1152/physrev.00013.2007, 2888531, 18195085.
7. Forbes SJ, Russo FP, Rey V, Burra P, Rugge M, Wright NA, Alison MR. A significant proportion of myofibroblasts are of bone marrow origin in human liver fibrosis. Gastroenterology 2004, 126:955-963. 10.1053/j.gastro.2004.02.025, 15057733.
8. Russo FP, Alison MR, Bigger BW, Amofah E, Florou A, Amin F, Bou-Gharios G, Jeffery R, Iredale JP, Forbes SJ. The bone marrow functionally contributes to liver fibrosis. Gastroenterology 2006, 130:1807-1821. 10.1053/j.gastro.2006.01.036, 16697743.
9. Valfrè di Bonzo L, Ferrero I, Cravanzola C, Mareschi K, Rustichelli D, Novo E, Sanavio F, Cannito S, Zamara E, Bertero M, Davit A, Francica S, Novelli F, Colombatto S, Fagioli F, Parola M. Human mesenchymal stem cells as a two-edged sword in hepatic regenerative medicine: engraftment and hepatocyte differentiation versus profibrogenic potential. Gut 2008, 57:223-231. 10.1136/gut.2006.111617, 17639088.
10. Kisseleva T, Uchinami H, Feirt N, Quintana-Bustamante O, Segovia JC, Schwabe RF, Brenner DA. Bone marrow-derived fibrocytes participate in pathogenesis of liver fibrosis. J Hepatol 2006, 45:429-438. 10.1016/j.jhep.2006.04.014, 16846660.
11. Zeisberg M, Yang C, Martino M, Duncan MB, Rieder F, Tanjore H, Kalluri R. Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition. J Biol Chem 2007, 282:23337-23347. 10.1074/jbc.M700194200, 17562716.
12. Xia J-L, Dai C, Michalopoulos GK, Liu Y. Hepatocyte growth factor attenuates liver fibrosis induced by bile duct ligation. Am J Pathol 2006, 168:1500-1512. 10.2353/ajpath.2006.050747, 1606599, 16651617.
13. Pinzani M, Marra F. Cytokine receptor and signalling in hepatic stellate cells. Sem Liver Dis 2001, 21:397-417.
14. Bataller R, Brenner DA. Liver fibrosis. J Clin Invest 2005, 115:209-218. 546435, 15690074.
15. Iredale JP. Models of liver fibrosis: exploring the dynamic nature of inflammation and repair in a solid organism. J Clin Invest 2007, 117:539-548. 10.1172/JCI30542, 1804370, 17332881.
16. Kallis YN, Alison MR, Forbes SJ. Bone marrow stem cells and liver disease. Gut 2007, 56:716-724. 10.1136/gut.2006.098442, 1942133, 17145739.
17. El-Sharkawy AM, Oakley F, Mann D. The role and regulation of hepatic stellate cells apoptosis in reversal of liver fibrosis. Apoptosis 2005, 10:927-939. 10.1007/s10495-005-1055-4, 16151628.
18. Novo E, Parola M. Redox mechanisms in hepatic chronic wound healing and fibrogenesis. Fibrogen Tissue Rep 2008, 1:5.
19. Pinzani M. Liver fibrosis. Springer Semin Immunopathol 2000, 21:475-490.
20. Ikejima K, Honda H, Yoshikawa M, Hirose M, Kitamura T, Takei Y, Sato N. Leptin augments inflammatory and profibrogenic responses in the murine liver induced by hepatotoxic chemicals. Hepatology 2001, 34:288-297. 10.1053/jhep.2001.26518, 11481614.
21. Kitade M, Yoshiji H, Kojima H, Ikenaka Y, Noguchi R, Kaji K, Yoshii J, Yanase K, Namisaki T, Asada K, Yamazaki M, Tsujimoto T, Akahane T, Uemura M, Fukui H. Leptin-mediated neovascularization is a prerequisite for progression of nonalcoholic steatohepatitis in rats. Hepatology 2006, 44:983-991. 10.1002/hep.21338, 17006938.
22. Aleffi S, Petrai I, Bertolani C, Parola M, Colombatto S, Novo E, Vizzutti F, Anania FA, Milani S, Rombouts K, Laffi G, Pinzani M, Marra F. Upregulation of proinflammatory and proangiogenic cytokines by leptin in human hepatic stellate cells. Hepatology 2005, 42:1339-1348. 10.1002/hep.20965, 16317688.
23. Marra F, Gastaldelli A, Svegliati Baroni G, Tell G, Tiribelli C. Molecular basis and mechanisms of progression of non-alcoholic steatohepatitis. Trends Mol Med 2008, 14:72-81. 10.1016/j.molmed.2007.12.003, 18218340.
24. Medina J, Arroyo AG, Sanchez-Madrid F, Moreno-Otero R. Angiogenesis in chronic inflammatory liver disease. Hepatology 2004, 39:1185-1195. 10.1002/hep.20193, 15122744.
25. Novo E, Cannito S, Zamara E, Valfrè di Bonzo L, Caligiuri A, Cravanzola C, Compagnone A, Colombatto S, Marra F, Pinzani M, Parola M. Proangiogenic cytokines as hypoxia-dependent factors stimulating migration of human hepatic stellate cells. Am J Pathol 2007, 170:1942-1953. 10.2353/ajpath.2007.060887, 1899450, 17525262.
26. De Minicis S, Bataller R, Brenner DA. NADPH oxidase in the liver: defensive, offensive, or fibrogenic?. Gastroenterology 2006, 131:272-275. 10.1053/j.gastro.2006.05.048, 16831609.
27. Zhan SS, Jiang JX, Wu J, Halsted C, Friedman SL, Zern MA, Torok NJ. Phagocytosis of apoptotic bodies by hepatic stellate cells induces NADPH oxidase and is associated with liver fibrosis in vivo. Hepatology 2006, 43:435-445. 10.1002/hep.21093, 16496318.
28. Albano E. Oxidative mechanisms in the pathogenesis of alcoholic liver disease. Mol Asp Med 2008, 29:9-16.