메뉴 건너뛰기




Volumn 13, Issue 2, 2016, Pages 1413-1419

Role of autophagy on bone marrow mesenchymal stem-cell proliferation and differentiation into neurons

Author keywords

Autophagy; Bone marrow mesenchymal stem cells; Differentiation; Notch1; Proliferation

Indexed keywords

3 METHYLADENINE; CHLOROQUINE; MICROTUBULE ASSOCIATED PROTEIN 2; NEURON SPECIFIC ENOLASE; NOTCH1 RECEPTOR; RAPAMYCIN; TRANSCRIPTION FACTOR HES 1; NOTCH RECEPTOR;

EID: 84956959812     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.4673     Document Type: Article
Times cited : (19)

References (47)
  • 1
    • 80053312481 scopus 로고    scopus 로고
    • Autophagy and lipid metabolism coordinately modulate life span in germline-less C
    • Lapierre LR, Gelino S, Meléndez A and Hansen M: Autophagy and lipid metabolism coordinately modulate life span in germline-less C. elegans. Curr Biol 21: 1507-1514, 2011.
    • (2011) Elegans. Curr Biol , vol.21 , pp. 1507-1514
    • Lapierre, L.R.1    Gelino, S.2    Meléndez, A.3    Hansen, M.4
  • 2
    • 39149111914 scopus 로고    scopus 로고
    • Roles of autophagy and mTOR signaling in neuronal differentiation of mouse neuroblastoma cells
    • Zeng M and Zhou JN: Roles of autophagy and mTOR signaling in neuronal differentiation of mouse neuroblastoma cells. Cell Signal 20: 659-665, 2008.
    • (2008) Cell Signal , vol.20 , pp. 659-665
    • Zeng, M.1    Zhou, J.N.2
  • 3
    • 84877341629 scopus 로고    scopus 로고
    • Notch signaling: Genetics and structure
    • Greenwald I and Kovall R: Notch signaling: Genetics and structure. WormBook 17: 1-28, 2013.
    • (2013) WormBook , vol.17 , pp. 1-28
    • Greenwald, I.1    Kovall, R.2
  • 4
    • 33750566665 scopus 로고    scopus 로고
    • Notch signaling in stem cell systems
    • Chiba S: Notch signaling in stem cell systems. Stem cells 24: 2437-2447, 2006.
    • (2006) Stem Cells , vol.24 , pp. 2437-2447
    • Chiba, S.1
  • 5
    • 33747623018 scopus 로고    scopus 로고
    • Notch signalling: A simple pathway becomes complex
    • Bray SJ: Notch signalling: A simple pathway becomes complex. Nat Rev Mol Cell Biol 7: 678-689, 2006.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 678-689
    • Bray, S.J.1
  • 7
    • 84863250460 scopus 로고    scopus 로고
    • Molecular targeting regulation of proliferation and differentiation of the bone marrow-derived mesenchymal stem cells or mesenchymal stromal cells
    • Chen BY, Wang X, Chen LW and Luo ZJ: Molecular targeting regulation of proliferation and differentiation of the bone marrow-derived mesenchymal stem cells or mesenchymal stromal cells. Curr Drug Targets 13: 561-571, 2012.
    • (2012) Curr Drug Targets , vol.13 , pp. 561-571
    • Chen, B.Y.1    Wang, X.2    Chen, L.W.3    Luo, Z.J.4
  • 8
    • 0034663515 scopus 로고    scopus 로고
    • Adult rat and human bone marrow stromal cells differentiate into neurons
    • Woodbury D, Schwarz EJ, Prockop DJ and Black IB: Adult rat and human bone marrow stromal cells differentiate into neurons. J Neurosci Res 61: 364-370, 2000.
    • (2000) J Neurosci Res , vol.61 , pp. 364-370
    • Woodbury, D.1    Schwarz, E.J.2    Prockop, D.J.3    Black, I.B.4
  • 9
    • 84934275819 scopus 로고    scopus 로고
    • Efficient in vitro labeling rabbit bone marrow-derived mesenchymal stem cells with SPIO and differentiating into neural-like cells
    • Zhang R, Li J and Xie J: Efficient in vitro labeling rabbit bone marrow-derived mesenchymal stem cells with SPIO and differentiating into neural-like cells. Mol Cells 37: 650-655, 2014.
    • (2014) Mol Cells , vol.37 , pp. 650-655
    • Zhang, R.1    Li, J.2    Xie, J.3
  • 10
    • 58449135981 scopus 로고    scopus 로고
    • Why are MSCs therapeutic?. New data: New insight
    • Caplan AI: Why are MSCs therapeutic? New data: New insight. J Pathol 217: 318-324, 2009.
    • (2009) J Pathol , vol.217 , pp. 318-324
    • Caplan, A.I.1
  • 11
    • 84902003449 scopus 로고    scopus 로고
    • Intravenous transplantation of bone marrow mesenchymal stem cells promotes neural regeneration after traumatic brain injury
    • Anbari F, Khalili MA, Bahrami AR, Khoradmehr A, Sadeghian F, Fesahat F and Nabi A: Intravenous transplantation of bone marrow mesenchymal stem cells promotes neural regeneration after traumatic brain injury. Neural Regen Res 9: 919-923, 2014.
    • (2014) Neural Regen Res , vol.9 , pp. 919-923
    • Anbari, F.1    Khalili, M.A.2    Bahrami, A.R.3    Khoradmehr, A.4    Sadeghian, F.5    Fesahat, F.6    Nabi, A.7
  • 12
    • 79952987670 scopus 로고    scopus 로고
    • MicroRNA-9 promotes differentiation of mouse bone mesenchymal stem cells into neurons by Notch signaling
    • Jing L, Jia Y, Lu J, Han R, Li J, Wang S, Peng T and Jia Y: MicroRNA-9 promotes differentiation of mouse bone mesenchymal stem cells into neurons by Notch signaling. Neuroreport 22: 206-211, 2011.
    • (2011) Neuroreport , vol.22 , pp. 206-211
    • Jing, L.1    Jia, Y.2    Lu, J.3    Han, R.4    Li, J.5    Wang, S.6    Peng, T.7    Jia, Y.8
  • 14
    • 77955908881 scopus 로고    scopus 로고
    • A novel Gfer-Drp1 link in preserving mitochondrial dynamics and function in pluripotent stem cells
    • Todd LR, Gomathinayagam R and Sankar U: A novel Gfer-Drp1 link in preserving mitochondrial dynamics and function in pluripotent stem cells. Autophagy 6: 821-822, 2010.
    • (2010) Autophagy , vol.6 , pp. 821-822
    • Todd, L.R.1    Gomathinayagam, R.2    Sankar, U.3
  • 16
    • 50249103834 scopus 로고    scopus 로고
    • The cell biology of autophagy in metazoans: A developing story
    • Meléndez A and Neufeld TP: The cell biology of autophagy in metazoans: A developing story. Development 135: 2347-2360, 2008.
    • (2008) Development , vol.135 , pp. 2347-2360
    • Meléndez, A.1    Neufeld, T.P.2
  • 17
    • 39849109338 scopus 로고    scopus 로고
    • Autophagy fights disease through cellular self-digestion
    • Mizushima N, Levine B, Cuervo AM and Klionsky DJ: Autophagy fights disease through cellular self-digestion. Nature 451: 1069-1075, 2008.
    • (2008) Nature , vol.451 , pp. 1069-1075
    • Mizushima, N.1    Levine, B.2    Cuervo, A.M.3    Klionsky, D.J.4
  • 18
    • 77951214016 scopus 로고    scopus 로고
    • Mammalian autophagy: Core molecular machinery and signaling regulation
    • Yang Z and Klionsky DJ: Mammalian autophagy: Core molecular machinery and signaling regulation. Curr Opin Cell Biol 22: 124-131, 2010.
    • (2010) Curr Opin Cell Biol , vol.22 , pp. 124-131
    • Yang, Z.1    Klionsky, D.J.2
  • 19
    • 27644484061 scopus 로고    scopus 로고
    • Autophagy: Molecular machinery for self-eating
    • Yorimitsu T and Klionsky DJ: Autophagy: Molecular machinery for self-eating. Cell Death Differ 12 (Suppl 2): S1542-S1552, 2005.
    • (2005) Cell Death Differ , vol.12 , pp. S1542-S1552
    • Yorimitsu, T.1    Klionsky, D.J.2
  • 21
    • 79953139746 scopus 로고    scopus 로고
    • Drosophila as a model system to study autophagy
    • Zirin J and Perrimon N: Drosophila as a model system to study autophagy. Semin Immunopathol 32: 363-372, 2010.
    • (2010) Semin Immunopathol , vol.32 , pp. 363-372
    • Zirin, J.1    Perrimon, N.2
  • 23
    • 33644984490 scopus 로고    scopus 로고
    • A new description of cellular quiescence
    • Coller HA, Sang L and Roberts JM: A new description of cellular quiescence. PLoS Biol 4: e83, 2006.
    • (2006) PLoS Biol , vol.4 , pp. e83
    • Coller, H.A.1    Sang, L.2    Roberts, J.M.3
  • 24
    • 84872340936 scopus 로고    scopus 로고
    • Tightrope act: Autophagy in stem cell renewal, differentiation, proliferation and aging
    • Phadwal K, Watson AS and Simon AK: Tightrope act: Autophagy in stem cell renewal, differentiation, proliferation and aging. Cell Mol Life Sci 70: 89-103, 2013.
    • (2013) Cell Mol Life Sci , vol.70 , pp. 89-103
    • Phadwal, K.1    Watson, A.S.2    Simon, A.K.3
  • 25
    • 80052382925 scopus 로고    scopus 로고
    • Lack of autophagy in the hematopoietic system leads to loss of hematopoietic stem cell function and dysregulated myeloid proliferation
    • Mortensen M, Watson AS and Simon AK: Lack of autophagy in the hematopoietic system leads to loss of hematopoietic stem cell function and dysregulated myeloid proliferation. Autophagy 7: 1069-1070, 2011.
    • (2011) Autophagy , vol.7 , pp. 1069-1070
    • Mortensen, M.1    Watson, A.S.2    Simon, A.K.3
  • 28
    • 77954955537 scopus 로고    scopus 로고
    • The emerging role of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin signaling network in normal myelopoiesis and leukemogenesis
    • Martelli AM, Evangelisti C, Chiarini F, Grimaldi C, Cappellini A, Ognibene A and McCubrey JA: The emerging role of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin signaling network in normal myelopoiesis and leukemogenesis. Biochim Biophys Acta 1803: 991-1002, 2010.
    • (2010) Biochim Biophys Acta , vol.1803 , pp. 991-1002
    • Martelli, A.M.1    Evangelisti, C.2    Chiarini, F.3    Grimaldi, C.4    Cappellini, A.5    Ognibene, A.6    McCubrey, J.A.7
  • 29
    • 77951217000 scopus 로고    scopus 로고
    • Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class i and III phosphoinositide 3-kinase
    • Wu YT, Tan HL, Shui G, Bauvy C, Huang Q, Wenk MR, Ong CN, Codogno P and Shen HM: Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinase. J Biol Chem 285: 10850-10861, 2010.
    • (2010) J Biol Chem , vol.285 , pp. 10850-10861
    • Wu, Y.T.1    Tan, H.L.2    Shui, G.3    Bauvy, C.4    Huang, Q.5    Wenk, M.R.6    Ong, C.N.7    Codogno, P.8    Shen, H.M.9
  • 30
    • 79956014819 scopus 로고    scopus 로고
    • Induction of lysosomal dilatation, arrested autophagy and cell death by chloroquine in cultured ARPE-19 cells
    • Yoon YH, Cho KS, Hwang JJ, Lee SJ, Choi JA and Koh JY: Induction of lysosomal dilatation, arrested autophagy and cell death by chloroquine in cultured ARPE-19 cells. Invest Ophthalmol Vis Sci 51: 6030-6037, 2010.
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , pp. 6030-6037
    • Yoon, Y.H.1    Cho, K.S.2    Hwang, J.J.3    Lee, S.J.4    Choi, J.A.5    Koh, J.Y.6
  • 31
    • 84870389278 scopus 로고    scopus 로고
    • Coordinated time-dependent modulation of AMPK/Akt/mTOR signaling and autophagy controls osteogenic differentiation of human mesenchymal stem cells
    • Pantovic A, Krstic A, Janjetovic K, Kocic J, Harhaji-Trajkovic L, Bugarski D and Trajkovic V: Coordinated time-dependent modulation of AMPK/Akt/mTOR signaling and autophagy controls osteogenic differentiation of human mesenchymal stem cells. Bone 52: 524-531, 2013.
    • (2013) Bone , vol.52 , pp. 524-531
    • Pantovic, A.1    Krstic, A.2    Janjetovic, K.3    Kocic, J.4    Harhaji-Trajkovic, L.5    Bugarski, D.6    Trajkovic, V.7
  • 32
    • 84869433016 scopus 로고    scopus 로고
    • Increased SCF/c-kit by hypoxia promotes autophagy of human placental chorionic plate-derived mesenchymal stem cells via regulating the phosphorylation of mTOR
    • Lee Y, Jung J, Cho KJ, Lee SK, Park JW, Oh IH and Kim GJ: Increased SCF/c-kit by hypoxia promotes autophagy of human placental chorionic plate-derived mesenchymal stem cells via regulating the phosphorylation of mTOR. J Cell Biochem 114: 79-88, 2013.
    • (2013) J Cell Biochem , vol.114 , pp. 79-88
    • Lee, Y.1    Jung, J.2    Cho, K.J.3    Lee, S.K.4    Park, J.W.5    Oh, I.H.6    Kim, G.J.7
  • 33
    • 84900901607 scopus 로고    scopus 로고
    • Hypoxia induces autophagy of bone marrow-derived mesenchymal stem cells via activation of ERK1/2
    • Wu J, Niu J, Li X, Li Y, Wang X, Lin J and Zhang F: Hypoxia induces autophagy of bone marrow-derived mesenchymal stem cells via activation of ERK1/2. Cell Physiol Biochem 33: 1467-1474, 2014.
    • (2014) Cell Physiol Biochem , vol.33 , pp. 1467-1474
    • Wu, J.1    Niu, J.2    Li, X.3    Li, Y.4    Wang, X.5    Lin, J.6    Zhang, F.7
  • 34
    • 84896322529 scopus 로고    scopus 로고
    • Atorvastatin induces autophagy of mesenchymal stem cells under hypoxia and serum deprivation conditions by activating the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway
    • Li N, Zhang Q, Qian HY, Jin C, Yang Y and Gao R: Atorvastatin induces autophagy of mesenchymal stem cells under hypoxia and serum deprivation conditions by activating the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway. Chin Med J (Engl) 127: 1046-1051, 2014.
    • (2014) Chin Med J (Engl) , vol.127 , pp. 1046-1051
    • Li, N.1    Zhang, Q.2    Qian, H.Y.3    Jin, C.4    Yang, Y.5    Gao, R.6
  • 35
    • 84908509128 scopus 로고    scopus 로고
    • Autophagy induction is a survival response against oxidative stress in bone marrow-derived mesenchymal stromal cells
    • Song C, Song C and Tong F: Autophagy induction is a survival response against oxidative stress in bone marrow-derived mesenchymal stromal cells. Cytotherapy 26: 1361-1370, 2014.
    • (2014) Cytotherapy , vol.26 , pp. 1361-1370
    • Song, C.1    Song, C.2    Tong, F.3
  • 36
    • 84893714063 scopus 로고    scopus 로고
    • Increased leptin by hypoxic-preconditioning promotes autophagy of mesenchymal stem cells and protects them from apoptosis
    • Wang L, Hu X, Zhu W, Jiang Z, Zhou Y, Chen P and Wang J: Increased leptin by hypoxic-preconditioning promotes autophagy of mesenchymal stem cells and protects them from apoptosis. Sci China Life Sci 57: 171-180, 2014.
    • (2014) Sci China Life Sci , vol.57 , pp. 171-180
    • Wang, L.1    Hu, X.2    Zhu, W.3    Jiang, Z.4    Zhou, Y.5    Chen, P.6    Wang, J.7
  • 37
    • 80053391464 scopus 로고    scopus 로고
    • CAMP induces autophagy via a novel pathway involving ERK, cyclin e and Beclin 1
    • Ugland H, Naderi S, Brech A, Collas P and Blomhoff HK: CAMP induces autophagy via a novel pathway involving ERK, cyclin E and Beclin 1. Autophagy 7: 1199-1211, 2011.
    • (2011) Autophagy , vol.7 , pp. 1199-1211
    • Ugland, H.1    Naderi, S.2    Brech, A.3    Collas, P.4    Blomhoff, H.K.5
  • 38
    • 8344242220 scopus 로고    scopus 로고
    • Autophagy in health and disease: A double-edged sword
    • Shintani T and Klionsky DJ: Autophagy in health and disease: A double-edged sword. Science 306: 990-995, 2004.
    • (2004) Science , vol.306 , pp. 990-995
    • Shintani, T.1    Klionsky, D.J.2
  • 40
    • 84908225505 scopus 로고    scopus 로고
    • Role of autophagy and mTOR signaling in neural differentiation of bone marrow mesenchymal stem cells
    • Li Y, Wang C, Zhang G, Wang X, Duan R, Gao H, Peng T, Teng J and Jia Y: Role of autophagy and mTOR signaling in neural differentiation of bone marrow mesenchymal stem cells. Cell Biol Int 38: 1337-1343, 2014.
    • (2014) Cell Biol Int , vol.38 , pp. 1337-1343
    • Li, Y.1    Wang, C.2    Zhang, G.3    Wang, X.4    Duan, R.5    Gao, H.6    Peng, T.7    Teng, J.8    Jia, Y.9
  • 41
    • 84891768014 scopus 로고    scopus 로고
    • Hesperetin activates the Notch1 signaling cascade, causes apoptosis, and induces cellular differentiation in anaplastic thyroid cancer
    • Patel PN, Yu XM, Jaskula-Sztul R and Chen H: Hesperetin activates the Notch1 signaling cascade, causes apoptosis, and induces cellular differentiation in anaplastic thyroid cancer. Ann Surg Oncol 21 Suppl 4: S497-S504, 2014.
    • (2014) Ann Surg Oncol , vol.21 , pp. S497-S504
    • Patel, P.N.1    Yu, X.M.2    Jaskula-Sztul, R.3    Chen, H.4
  • 42
    • 84907075560 scopus 로고    scopus 로고
    • NOTCH1 signaling contributes to cell growth, anti-apoptosis and metastasis in salivary adenoid cystic carcinoma
    • Su BH, Qu J, Song M, Huang XY, Hu XM, Xie J, Zhao Y, Ding LC, She L, Chen J, et al: NOTCH1 signaling contributes to cell growth, anti-apoptosis and metastasis in salivary adenoid cystic carcinoma. Oncotarget 5: 6885-6895, 2014.
    • (2014) Oncotarget , vol.5 , pp. 6885-6895
    • Su, B.H.1    Qu, J.2    Song, M.3    Huang, X.Y.4    Hu, X.M.5    Xie, J.6    Zhao, Y.7    Ding, L.C.8    She, L.9    Chen, J.10
  • 44
    • 38449086118 scopus 로고    scopus 로고
    • Expression changes of Notch-related genes during the differentiation of human mesenchymal stem cells into neurons
    • In Chinese
    • Xing Y, Bai RY, Yan WH, Han XF, Duan P, Xu Y and Fan ZG: Expression changes of Notch-related genes during the differentiation of human mesenchymal stem cells into neurons. Sheng Li Xue Bao 59: 267-272, 2007 (In Chinese).
    • (2007) Sheng Li Xue Bao , vol.59 , pp. 267-272
    • Xing, Y.1    Bai, R.Y.2    Yan, W.H.3    Han, X.F.4    Duan, P.5    Xu, Y.6    Fan, Z.G.7
  • 45
    • 84901313025 scopus 로고    scopus 로고
    • How to take autophagy and endocytosis up a notch
    • Barth JM and Köhler K: How to take autophagy and endocytosis up a notch. Biomed Res Int 2014: 960803, 2014.
    • (2014) Biomed Res Int , vol.2014 , pp. 960803
    • Barth, J.M.1    Köhler, K.2
  • 46
    • 84883253496 scopus 로고    scopus 로고
    • A targeted genetic modifier screen links the SWI2/SNF2 protein domino to growth and autophagy genes in Drosophila melanogaster
    • Kwon MH, Callaway H, Zhong J and Yedvobnick B: A targeted genetic modifier screen links the SWI2/SNF2 protein domino to growth and autophagy genes in Drosophila melanogaster. G3 (Bethesda) 3: 815-825, 2013.
    • (2013) G3 (Bethesda) , vol.3 , pp. 815-825
    • Kwon, M.H.1    Callaway, H.2    Zhong, J.3    Yedvobnick, B.4
  • 47
    • 77956309044 scopus 로고    scopus 로고
    • Endocytosis and intracellular trafficking of Notch and its ligands
    • Yamamoto S, Charng WL and Bellen HJ: Endocytosis and intracellular trafficking of Notch and its ligands. Curr Top Dev Biol 92: 165-200, 2010.
    • (2010) Curr Top Dev Biol , vol.92 , pp. 165-200
    • Yamamoto, S.1    Charng, W.L.2    Bellen, H.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.