Coordinated time-dependent modulation of AMPK/Akt/mTOR signaling and autophagy controls osteogenic differentiation of human mesenchymal stem cells

Bone

Volumn 52, Issue 1, 2013, Pages 524-531

  Pantovic, Aleksandar ^a   Krstic, Aleksandra ^a   Janjetovic, Kristina ^a   Kocic, Jelena ^a   Harhaji Trajkovic, Ljubica ^a   Bugarski, Diana ^a   Trajkovic, Vladimir ^a  

^a UNIVERSITY OF BELGRADE   (Serbia)

Author keywords

Akt; AMPK; Autophagy; Mesenchymal stem cells; MTOR; Osteoblasts

Indexed keywords

ALKALINE PHOSPHATASE; AMMONIUM CHLORIDE; BAFILOMYCIN A1; BECLIN 1; BONE MORPHOGENETIC PROTEIN 2; CHLOROQUINE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; MICROTUBULE ASSOCIATED PROTEIN 1; MICROTUBULE ASSOCIATED PROTEIN 1 LIGHT CHAIN 3BETA; OSTEOCALCIN; PROTEIN KINASE B; PROTEIN KINASE INHIBITOR; PROTEIN P62; RAPAMYCIN; S6 KINASE; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG;

ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL DIFFERENTIATION; CONTROLLED STUDY; CYTOCHEMISTRY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MESENCHYMAL STEM CELL; OSTEOBLAST; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR DOWN REGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TOOTH PULP; UPREGULATION;

ADENYLATE KINASE; AUTOPHAGY; CELL DIFFERENTIATION; FEMALE; HUMANS; OSTEOGENESIS; SIGNAL TRANSDUCTION; STEM CELLS; TOR SERINE-THREONINE KINASES;

EID: 84870389278     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2012.10.024     Document Type: Article

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