Simultaneous or Sequential Orthogonal Gradient Formation in a 3D Cell Culture Microfluidic Platform

Small

Volumn 12, Issue 5, 2016, Pages 612-622

  Uzel, Sebastien G M ^a   Amadi, Ovid C ^b   Pearl, Taylor M ^a   Lee, Richard T ^c   So, Peter T C ^a   Kamm, Roger D ^a  

^a Massachusetts Institute of Technology   (United States)

^b HARVARD MIT DIVISION OF HEALTH SCIENCES AND TECHNOLOGY   (United States)

^c HARVARD UNIVERSITY   (United States)

Author keywords

cancer cell migration; dynamic chemotaxis; microfluidics; orthogonal gradients; stem cell differentiation

Indexed keywords

BIOCHEMISTRY; BRAIN; CELL CULTURE; CELLS; CYTOLOGY; DISEASES; MICROFLUIDICS; NEURONS; STEM CELLS; TISSUE; TISSUE ENGINEERING;

BIOLOGICAL PHENOMENA; CANCER CELLS; CONCENTRATION PROFILES; CONCENTRATION-DEPENDENT; LINEAR CONCENTRATION GRADIENTS; MICROFLUIDIC PLATFORMS; ORTHOGONAL GRADIENTS; STEM CELL DIFFERENTIATION;

SCAFFOLDS (BIOLOGY);

CYCLOHEXYLAMINE DERIVATIVE; HYDROGEL; RETINOIC ACID; SAG COMPOUND; THIOPHENE DERIVATIVE;

ANIMAL; CELL CULTURE TECHNIQUE; CELL DIFFERENTIATION; CELL LINE; CHEMOTAXIS; CYTOLOGY; DEVICES; DRUG EFFECTS; EMBRYOLOGY; EQUIPMENT DESIGN; HUMAN; HYDROGEL; MICROFLUIDIC ANALYSIS; MOTONEURON; MOUSE; NEURAL TUBE; PHARMACOLOGY; PROCEDURES; TIME FACTOR;

ANIMALS; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL LINE; CHEMOTAXIS; CYCLOHEXYLAMINES; EQUIPMENT DESIGN; HUMANS; HYDROGEL; MICE; MICROFLUIDIC ANALYTICAL TECHNIQUES; MOTOR NEURONS; NEURAL TUBE; THIOPHENES; TIME FACTORS; TRETINOIN;

EID: 84956904595     PISSN: 16136810     EISSN: 16136829     Source Type: Journal    
DOI: 10.1002/smll.201501905     Document Type: Article

References (61)

1. G. R. Dubyak, Adv. Physiol. Educ. 2004, 28, 143.
2. S. Boyden, J. Exp. Med. 1962, 115, 453.
3. D. Zicha, G. A. Dunn, A. F. Brown, J. Cell Sci. 1991, 99, 769.
4. S. H. Zigmond, J. Cell Biol. 1977, 75, 606.
5. Y. Xia, G. M. Whitesides, Annu. Rev. Mater. Sci. 1998, 28, 153.
6. N. L. Jeon, S. K. W. Dertinger, D. T. Chiu, I. S. Choi, A. D. Stroock, G. M. Whitesides, Langmuir 2000, 16, 8311.
7. W. J. Polacheck, R. Li, S. G. M. Uzel, R. D. Kamm, Lab Chip 2013, 13, 2252.
8. J. Li, F. Lin, Trends Cell Biol. 2011, 21, 489.
9. A. Pavesi, F. Piraino, G. B. Fiore, K. M. Farino, M. Moretti, M. Rasponi, Lab Chip 2011, 11, 1593.
10. S.-J. Wang, W. Saadi, F. Lin, C. Minh-Canh Nguyen, N. Li Jeon, Exp. Cell Res. 2004, 300, 180.
11. S. K. W. Dertinger, X. Jiang, Z. Li, V. N. Murthy, G. M. Whitesides, Proc. Natl. Acad. Sci. USA 2002, 99, 12542.
12. J. Y. Park, S. K. Kim, D. H. Woo, E. J. Lee, J. H. Kim, S. H. Lee, Stem Cells 2009, 27, 2646.
13. W. Saadi, S. W. Rhee, F. Lin, B. Vahidi, B. G. Chung, N. L. Jeon, Biomed. Microdevices 2007, 9, 627.
14. L. J. Millet, M. E. Stewart, R. G. Nuzzo, M. U. Gillette, Lab Chip 2010, 10, 1525.
15. T. M. Keenan, C. W. Frevert, A. Wu, V. Wong, A. Folch, Lab Chip 2010, 10, 116.
16. B. Harink, S. Le Gac, D. Barata, C. van Blitterswijk, P. Habibovic, Electrophoresis 2015, 36, 475.
17. B. Meier, A. Zielinski, C. Weber, D. Arcizet, S. Youssef, T. Franosch, J. O. Rädler, D. Heinrich, Proc. Natl. Acad. Sci. U SA 2011, 108, 11417.
18. Y. Liu, J. Sai, A. Richmond, J. P. Wikswo, Biomed. Microdevices 2008, 10, 499.
19. D. Irimia, S.-Y. Liu, W. G. Tharp, A. Samadani, M. Toner, M. C. Poznansky, Lab Chip 2006, 6, 191.
20. M. Skoge, H. Yue, M. Erickstad, A. Bae, H. Levine, A. Groisman, Proc. Natl. Acad. Sci. USA 2014, 111, 1.
21. J. Atencia, J. Morrow, L. E. Locascio, Lab Chip 2009, 9, 2707.
22. E. Choi, H. Chang, C. Y. Lim, T. Kim, J. Park, Lab Chip 2012, 12, 3968.
23. M.-E. Brett, R. Deflorio, D. E. Stone, D. T. Eddington, Lab Chip 2012, 12, 3127.
24. J. Wu, X. Wu, F. Lin, Lab Chip 2013, 13, 2484.
25. D. Irimia, Annu. Rev. Biomed. Eng. 2010, 12, 259.
26. I. K. Zervantonakis, S. K. Hughes-Alford, J. L. Charest, J. S. Condeelis, F. B. Gertler, R. D. Kamm, Proc. Natl. Acad. Sci. USA 2012, 109, 13515.
27. O. C. Amadi, M. L. Steinhauser, Y. Nishi, S. Chung, R. D. Kamm, A. P. McMahon, R. T. Lee, Biomed. Microdevices 2010, 12, 1027.
28. U. Haessler, Y. Kalinin, M. A. Swartz, M. Wu, Biomed. Microdevices 2009, 11, 827.
29. Y. Shin, S. Han, J. S. Jeon, K. Yamamoto, I. K. Zervantonakis, R. Sudo, R. D. Kamm, S. Chung, Nat. Protoc. 2012, 7, 1247.
30. W. A. Farahat, L. B. Wood, I. K. Zervantonakis, A. Schor, S. Ong, D. Neal, R. D. Kamm, H. H. Asada, PLoS One 2012, DOI: 10.1371/journal.pone.0037333.
31. B. Mosadegh, C. Huango, J. W. Park, H. S. Shin, B. G. Chung, S. K. Hwang, K. H. Lee, H. J. Kim, J. Brody, N. L. Jeon, Langmuir 2007, 23, 10910.
32. A. Banerjee, Y. Shuai, R. Dixit, I. Papautsky, D. Klotzkin, J. Lumin. 2010, 130, 1095.
33. M. Arrio-Dupont, S. Cribier, G. Foucault, P. F. Devaux, A. d'Albis, Biophys. J. 1996, 70, 2327.
34. J. R. Lawrence, G. M. Wolfaardt, D. R. Korber, Appl. Env. Microbiol. 1994, 60, 1166.
35. M. Maden, Nat. Rev. Neurosci. 2007, 8, 755.
36. H. Wichterle, I. Lieberam, J. A. Porter, T. M. Jessell, Cell 2002, 110, 385.
37. E. Dessaud, A. P. McMahon, J. Briscoe, Development 2008, 135, 2489.
38. J. Briscoe, J. Ericson, Curr. Opin. Neurobiol. 2001, 11, 43.
39. Y. Okada, T. Shimazaki, G. Sobue, H. Okano, Dev. Biol. 2004, 275, 124.
40. J. Ericson, J. Briscoe, P. Rashbass, V. van Heyningen, T. M. Jessell, Cold Spring Harbor Symp. Quant. Biol. 1997, 62, 451.
41. X.-J. Li, Z.-W. Du, E. D. Zarnowska, M. Pankratz, L. O. Hansen, R. A. Pearce, S.-C. Zhang, Nat. Biotechnol. 2005, 23, 215.
42. J. K. Chen, J. Taipale, K. E. Young, T. Maiti, P. A. Beachy, Proc. Natl. Acad. Sci. USA 2002, 99, 14071.
43. M. Frank-Kamenetsky, X. M. Zhang, S. Bottega, O. Guicherit, H. Wichterle, H. Dudek, D. Bumcrot, F. Y. Wang, S. Jones, J. Shulok, L. L. Rubin, J. A. Porter, J. Biol. 2002, 1, 10.
44. H. Wichterle, M. Peljto, Curr. Protoc. Stem Cell Biol. 2008, DOI: 10.1002/9780470151808.sc01h01s5.
45. C.-Y. Wu, D. Whye, R. W. Mason, W. Wang, J. Visualized Exp. 2012, 1, e3813.
46. T. Wada, M. Honda, I. Minami, N. Tooi, Y. Amagai, N. Nakatsuji, K. Aiba, PLoS One 2009, DOI: 10.1371/journal.pone.0006722.
47. W.-T. Fung, A. Beyzavi, P. Abgrall, N.-T. Nguyen, H.-Y. Li, Lab Chip 2009, 9, 2591.
48. W. J. Polacheck, I. K. Zervantonakis, R. D. Kamm, Cell. Mol. Life Sci. 2013, 70, 1335.
49. S. Rasheed, W. A. Nelson-Rees, E. M. Toth, P. Arnstein, M. B. Gardner, Cancer 1974, 33, 1027.
50. P. Zengel, A. Nguyen-Hoang, C. Schildhammer, R. Zantl, V. Kahl, E. Horn, BMC Cell Biol. 2011, 12, 21.
51. V. Niggli, M. Schmid, A. Nievergelt, Biochem. Biophys. Res. Commun. 2006, 343, 602.
52. R. G. Thorne, S. Hrabetová, C. Nicholson, J. Neurophysiol. 2004, 92, 3471.
53. W. J. Polacheck, J. L. Charest, R. D. Kamm, Proc. Natl. Acad. Sci. USA 2011, 108, 11115.
54. B. J. Dickson, Science 2002, 298, 1959.
55. L. S. Han, J. Appl. Mech. 1960, 27, 403.
56. Y. Shin, S. Han, J. S. Jeon, K. Yamamoto, I. K. Zervantonakis, R. Sudo, R. D. Kamm, Nat. Protocols 2012, 7, 1247.
57. V. Vickerman, J. Blundo, S. Chung, R. Kamm, Lab Chip 2008, 8, 1468.
58. A. J. Dy, A. Cosmanescu, J. Sluka, J. A. Glazier, D. Stupack, D. Amarie, J. Micromech. Microeng. 2014, 24, 057001.
59. M. A. Unger, H. P. Chou, T. Thorsen, A. Scherer, S. R. Quake, Science 2000, 288, 113.
60. C. Liu, D. Cui, H. Cai, X. Chen, Z. Geng, Electrophoresis 2006, 27, 2917.
61. J. H. Kang, Y. C. Kim, J.-K. Park, Lab Chip 2008, 8, 176.