A low resistance microfluidic system for the creation of stable concentration gradients in a defined 3D microenvironment

Biomedical Microdevices

Volumn 12, Issue 6, 2010, Pages 1027-1041

  Amadi, Ovid C ^a,b   Steinhauser, Matthew L ^b   Nishi, Yuichi ^c   Chung, Seok ^d   Kamm, Roger D ^e   McMahon, Andrew P ^c,f   Lee, Richard T ^b,f  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c HARVARD UNIVERSITY   (United States)

^d Korea University   (South Korea)

^e Massachusetts Institute of Technology Cambridge   (United States)

^f HARVARD STEM CELL INSTITUTE   (United States)

Author keywords

Chemotaxis; Concentration gradient; Microfluidic; Migration; Morphogen gradient; Morphogenesis

Indexed keywords

CHEMOTAXIS; CONCENTRATION GRADIENTS; MIGRATION; MORPHOGEN GRADIENTS; MORPHOGENESIS;

BIOCHEMISTRY; CONCENTRATION (PROCESS); FLUIDIC DEVICES; GELS; MORPHOLOGY; WELLS;

MICROFLUIDICS;

OLIGODENDROCYTE TRANSCRIPTION FACTOR 2; PLATELET DERIVED GROWTH FACTOR BB; SONIC HEDGEHOG PROTEIN; STROMAL CELL DERIVED FACTOR 1; TRANSCRIPTION FACTOR NKX2.2;

ANIMAL CELL; ARTICLE; CELL MIGRATION; CHEMOTAXIS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DEVICE; EMBRYONIC STEM CELL; FLOW RATE; HUMAN; HUMAN CELL; HYDROSTATIC PRESSURE; LEUKEMIA CELL LINE; MICROENVIRONMENT; MICROFLUIDICS; NONHUMAN; PRESSURE GRADIENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESISTOR CAPACITOR DEVICE; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CATTLE; CELL DIFFERENTIATION; CELL MOVEMENT; CHEMOTAXIS; ELECTRIC CAPACITANCE; ELECTRIC IMPEDANCE; EMBRYOID BODIES; GENE EXPRESSION REGULATION; HEDGEHOG PROTEINS; HUMANS; JURKAT CELLS; MICROFLUIDIC ANALYTICAL TECHNIQUES; MUSCLE, SMOOTH, VASCULAR; PLATELET-DERIVED GROWTH FACTOR; PRESSURE; T-LYMPHOCYTES;

ERINACEIDAE;

EID: 78049317952     PISSN: 13872176     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10544-010-9457-7     Document Type: Article

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