High-frequency vaccine-induced CD8+ T cells specific for an epitope naturally processed during infection with Mycobacterium tuberculosis do not confer protection

European Journal of Immunology

Volumn 44, Issue 6, 2014, Pages 1699-1709

  Lindenstrøm, Thomas ^a   Aagaard, Claus ^a   Christensen, Dennis ^a   Agger, Else M ^a   Andersen, Peter ^a  

^a STATENS SERUM INSTITUT   (Denmark)

Author keywords

CD8; Cross priming; Mycobacterial type VII secretion system; Protection; TB10.3 TB10.4

Indexed keywords

BCG VACCINE; EPITOPE; GAMMA INTERFERON; IMYNYPAM EPITOPE; RV 0288; UNCLASSIFIED DRUG;

ADOPTIVE TRANSFER; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL SECRETION SYSTEM; BACTERIAL VIRULENCE; CD8+ T LYMPHOCYTE; CELL EXPANSION; CELLULAR IMMUNITY; CONTROLLED STUDY; CROSS PRESENTATION; DNA FLANKING REGION; FEMALE; LUNG TUBERCULOSIS; LYMPHOCYTOTOXICITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; TYPE 7 SECRETION SYSTEM;

CD8; CROSS-PRIMING; MYCOBACTERIAL TYPE VII SECRETION SYSTEM; PROTECTION; TB10.3/TB10.4;

ANIMALS; ANTIGEN PRESENTATION; ANTIGENS, BACTERIAL; CD8-POSITIVE T-LYMPHOCYTES; DISEASE MODELS, ANIMAL; EPITOPES, T-LYMPHOCYTE; MICE; MYCOBACTERIUM TUBERCULOSIS; TUBERCULOSIS; TUBERCULOSIS VACCINES;

EID: 84901847046     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201344358     Document Type: Article

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