Human and Murine Clonal CD8+ T Cell Expansions Arise during Tuberculosis Because of TCR Selection

PLoS Pathogens

Volumn 11, Issue 5, 2015, Pages

  Nunes Alves, Cláudio ^a,b,c   Booty, Matthew G ^a,d   Carpenter, Stephen M ^a,e   Rothchild, Alissa C ^a,d   Martin, Constance J ^f   Desjardins, Danielle ^e   Steblenko, Katherine ^a   Kløverpris, Henrik N ^g,h,i   Madansein, Rajhmun ^h   Ramsuran, Duran ^g   Leslie, Alasdair ^g,h   Correia Neves, Margarida ^b,c   Behar, Samuel M ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MINHO   (Portugal)

^c UNIVERSITY OF MINHO   (Portugal)

^d HARVARD MEDICAL SCHOOL   (United States)

^e BRIGHAM AND WOMEN S HOSPITAL   (United States)

^f HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^g AFRICA HEALTH RESEARCH INSTITUTE   (South Africa)

^h UNIVERSITY OF KWAZULU NATAL   (South Africa)

ⁱ UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GRANZYME B; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR BETA CHAIN; TRANSPORTER ASSOCIATED WITH ANTIGEN PROCESSING 1; BCG VACCINE; EPITOPE; LYMPHOCYTE ANTIGEN RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; COMPLEMENTARITY DETERMINING REGION; CONTROLLED STUDY; CYTOTOXICITY ASSAY; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; LUNG GRANULOMA; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NEXT GENERATION SEQUENCING; NONHUMAN; TUBERCULOSIS; ANIMAL; ANTIGEN PRESENTATION; C57BL MOUSE; IMMUNOLOGY; LYMPHOCYTE ACTIVATION;

MURINAE; MYCOBACTERIUM TUBERCULOSIS;

ANIMALS; ANTIGEN PRESENTATION; CD8-POSITIVE T-LYMPHOCYTES; EPITOPES, T-LYMPHOCYTE; HUMANS; IMMUNODOMINANT EPITOPES; INTERFERON-GAMMA; LYMPHOCYTE ACTIVATION; MICE, INBRED C57BL; RECEPTORS, ANTIGEN, T-CELL; TUBERCULOSIS; TUBERCULOSIS VACCINES;

EID: 84930341569     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004849     Document Type: Article

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