The β2 clamp in the Mycobacterium tuberculosis DNA polymerase III αβ2 ε replicase promotes polymerization and reduces exonuclease activity

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Gu, Shoujin ^a,f   Li, Wenjuan ^a   Zhang, Hongtai ^a   Fleming, Joy ^a   Yang, Weiqiang ^b   Wang, Shihua ^b   Wei, Wenjing ^a   Zhou, Jie ^c   Zhu, Guofeng ^d   Deng, Jiaoyu ^e   Hou, Jian ^a   Zhou, Ying ^a   Lin, Shiqiang ^a,b   Zhang, Xian En ^a   Bi, Lijun ^a  

^a INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^b FUJIAN AGRICULTURE AND FORESTRY UNIVERSITY   (China)

^c Department of Pharmacy People's Hospital   (China)

^d SHANGHAI MUNICIPAL CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^e WUHAN INSTITUTE OF VIROLOGY   (China)

^f UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL DNA; DNA DIRECTED DNA POLYMERASE; DNA DIRECTED DNA POLYMERASE GAMMA; DNA REPLICASE; EXONUCLEASE; PROTEIN BINDING; PROTEIN SUBUNIT;

CHEMISTRY; DNA REPLICATION; ENZYMOLOGY; ISOLATION AND PURIFICATION; METABOLISM; MYCOBACTERIUM TUBERCULOSIS; POLYMERIZATION; PROTEIN SECONDARY STRUCTURE; PROTEIN SUBUNIT; STRUCTURE ACTIVITY RELATION;

DNA POLYMERASE III; DNA REPLICATION; DNA, BACTERIAL; DNA-DIRECTED DNA POLYMERASE; EXONUCLEASES; MYCOBACTERIUM TUBERCULOSIS; POLYMERIZATION; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN SUBUNITS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84956638813     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep18418     Document Type: Article

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