A direct proofreader-clamp interaction stabilizes the Pol III replicase in the polymerization mode

EMBO Journal

Volumn 32, Issue 9, 2013, Pages 1322-1333

  Jergic, Slobodan ^a   Horan, Nicholas P ^a   Elshenawy, Mohamed M ^b   Mason, Claire E ^a   Urathamakul, Thitima ^a   Ozawa, Kiyoshi ^a,c   Robinson, Andrew ^a,d   Goudsmits, Joris M H ^e   Wang, Yao ^a   Pan, Xuefeng ^a,f   Beck, Jennifer L ^a   Van Oijen, Antoine M ^d,e   Huber, Thomas ^c   Hamdan, Samir M ^b   Dixon, Nicholas E ^a  

^a UNIVERSITY OF WOLLONGONG   (Australia)

^b KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Saudi Arabia)

^c AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

^d UNIVERSITY OF GRONINGEN   (Netherlands)

^e HARVARD MEDICAL SCHOOL   (United States)

^f BEIJING INSTITUTE OF TECHNOLOGY   (China)

Author keywords

beta sliding clamp; DNA polymerase III; DNA replication; Escherichia coli; proofreading exonuclease

Indexed keywords

ENZYME; EXONUCLEASE; POLYMERASE III REPLICASE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CONTROLLED STUDY; DNA REPLICATION; DNA SYNTHESIS; DNA TEMPLATE; IN VITRO STUDY; MUTAGENESIS; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; REPLISOME;

AMINO ACID SEQUENCE; BINDING SITES; DNA POLYMERASE III; DNA REPLICATION; DNA, SINGLE-STRANDED; ENZYME STABILITY; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID;

ESCHERICHIA COLI;

EID: 84877631000     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2012.347     Document Type: Article

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