The chondrocyte clock gene Bmal1 controls cartilage homeostasis and integrity

Journal of Clinical Investigation

Volumn 126, Issue 1, 2016, Pages 365-376

  Dudek, Michal ^a   Gossan, Nicole ^a   Yang, Nan ^a   Im, Hee Jeong ^b   Ruckshanthi, Jayalath P D ^a   Yoshitane, Hikari ^c   Li, Xin ^b   Jin, Ding ^a   Wang, Ping ^a   Boudiffa, Maya ^d   Bellantuono, Ilaria ^d   Fukada, Yoshitaka ^c   Boot Handford, Ray P ^a,e   Meng, Qing Jun ^a,e  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b RUSH UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY OF TOKYO   (Japan)

^d UNIVERSITY OF SHEFFIELD   (United Kingdom)

^e UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACAN PROTEIN; COLLAGEN; COLLAGEN TYPE 2 ALPHA 1; MEMBRANE PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ARNTL; TRANSCRIPTION FACTOR NFATC2; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG; ARNTL PROTEIN, HUMAN; TRANSCRIPTION FACTOR NFAT; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; ARTICULAR CARTILAGE; BIOSYNTHESIS; CARTILAGE CELL; CARTILAGE DEGENERATION; CATABOLISM; CIRCADIAN RHYTHM; CONTROLLED STUDY; GENE EXPRESSION; GENE FUNCTION; GENE LOSS; HOMEOSTASIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MALE; MOUSE; NONHUMAN; OSTEOARTHRITIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; ANIMAL; CHONDROCYTE; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY; SEQUENCE ANALYSIS;

ANIMALS; ARNTL TRANSCRIPTION FACTORS; CARTILAGE, ARTICULAR; CHONDROCYTES; CIRCADIAN RHYTHM; HOMEOSTASIS; HUMANS; MALE; MICE; MICE, KNOCKOUT; NFATC TRANSCRIPTION FACTORS; OSTEOARTHRITIS; SEQUENCE ANALYSIS, RNA; TRANSFORMING GROWTH FACTOR BETA;

EID: 84956631950     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI82755     Document Type: Article

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