-
1
-
-
84875225940
-
Corticosteroid resistance in patients with asthma and chronic obstructive pulmonary disease
-
Barnes PJ. Corticosteroid resistance in patients with asthma and chronic obstructive pulmonary disease. J Allergy Clin Immunol 2013;131:636-645.
-
(2013)
J Allergy Clin Immunol
, vol.131
, pp. 636-645
-
-
Barnes, P.J.1
-
2
-
-
79954543523
-
Steroid resistance in severe asthma: Current mechanisms and future treatment
-
Durham A, Adcock IM, Tliba O. Steroid resistance in severe asthma: current mechanisms and future treatment. Curr Pharm Des 2011;17: 674-684.
-
(2011)
Curr Pharm des
, vol.17
, pp. 674-684
-
-
Durham, A.1
Adcock, I.M.2
Tliba, O.3
-
4
-
-
84859965263
-
Pathogenesis of severe asthma
-
Poon AH, Eidelman DH, Martin JG, Laprise C, Hamid Q. Pathogenesis of severe asthma. Clin Exp Allergy 2012;42:625-637.
-
(2012)
Clin Exp Allergy
, vol.42
, pp. 625-637
-
-
Poon, A.H.1
Eidelman, D.H.2
Martin, J.G.3
Laprise, C.4
Hamid, Q.5
-
5
-
-
79954510723
-
Immunopathogenesis of severe asthma
-
Brightling CE, Gupta S, Hollins F, Sutcliffe A, Amrani Y. Immunopathogenesis of severe asthma. Curr Pharm Des 2011;17: 667-673.
-
(2011)
Curr Pharm des
, vol.17
, pp. 667-673
-
-
Brightling, C.E.1
Gupta, S.2
Hollins, F.3
Sutcliffe, A.4
Amrani, Y.5
-
6
-
-
84899951712
-
Bronchial epithelial cells are rendered insensitive to glucocorticoid transactivation by transforming growth factor-beta1
-
Keenan CR, Mok JS, Harris T, Xia Y, Salem S, Stewart AG. Bronchial epithelial cells are rendered insensitive to glucocorticoid transactivation by transforming growth factor-beta1. Respir Res 2014; 15:55.
-
(2014)
Respir Res
, vol.15
, pp. 55
-
-
Keenan, C.R.1
Mok, J.S.2
Harris, T.3
Xia, Y.4
Salem, S.5
Stewart, A.G.6
-
7
-
-
84856760174
-
Interleukin-17A induces glucocorticoid insensitivity in human bronchial epithelial cells
-
Zijlstra GJ, Ten Hacken NH, Hoffmann RF, van Oosterhout AJ, Heijink IH. Interleukin-17A induces glucocorticoid insensitivity in human bronchial epithelial cells. Eur Respir J 2012;39:439-445.
-
(2012)
Eur Respir J
, vol.39
, pp. 439-445
-
-
Zijlstra, G.J.1
Ten Hacken, N.H.2
Hoffmann, R.F.3
Van Oosterhout, A.J.4
Heijink, I.H.5
-
8
-
-
77955350723
-
Induction of glucocorticoid receptor-beta expression in epithelial cells of asthmatic airways by T-helper type 17 cytokines
-
Vazquez-Tello A, Semlali A, Chakir J, Martin JG, Leung DY, Eidelman DH, Hamid Q. Induction of glucocorticoid receptor-beta expression in epithelial cells of asthmatic airways by T-helper type 17 cytokines. Clin Exp Allergy 2010;40:1312-1322.
-
(2010)
Clin Exp Allergy
, vol.40
, pp. 1312-1322
-
-
Vazquez-Tello, A.1
Semlali, A.2
Chakir, J.3
Martin, J.G.4
Leung, D.Y.5
Eidelman, D.H.6
Hamid, Q.7
-
9
-
-
37849037750
-
Airway smooth muscle cell as an inflammatory cell: Lessons learned from interferon signaling pathways
-
Tliba O, Amrani Y. Airway smooth muscle cell as an inflammatory cell: lessons learned from interferon signaling pathways. Proc Am Thorac Soc 2008;5:106-112.
-
(2008)
Proc Am Thorac Soc
, vol.5
, pp. 106-112
-
-
Tliba, O.1
Amrani, Y.2
-
10
-
-
31144477001
-
Fraktalkine produced by airway smooth muscle cells contributes to mast cell recruitment in asthma
-
El-Shazly A, Berger P, Girodet PO, Ousova O, Fayon M, Vernejoux JM, Marthan R, Tunon-de-Lara JM. Fraktalkine produced by airway smooth muscle cells contributes to mast cell recruitment in asthma. J Immunol 2006;176:1860-1868.
-
(2006)
J Immunol
, vol.176
, pp. 1860-1868
-
-
El-Shazly, A.1
Berger, P.2
Girodet, P.O.3
Ousova, O.4
Fayon, M.5
Vernejoux, J.M.6
Marthan, R.7
Tunon-De-Lara, J.M.8
-
11
-
-
0032991806
-
Constitutive and cytokine-stimulated expression of eotaxin by human airway smooth muscle cells
-
Ghaffar O, Hamid Q, Renzi PM, Allakhverdi Z, Molet S, Hogg JC, Shore SA, Luster AD, Lamkhioued B. Constitutive and cytokine-stimulated expression of eotaxin by human airway smooth muscle cells. Am J Respir Crit Care Med 1999;159:1933-1942.
-
(1999)
Am J Respir Crit Care Med
, vol.159
, pp. 1933-1942
-
-
Ghaffar, O.1
Hamid, Q.2
Renzi, P.M.3
Allakhverdi, Z.4
Molet, S.5
Hogg, J.C.6
Shore, S.A.7
Luster, A.D.8
Lamkhioued, B.9
-
12
-
-
23444451466
-
CCR3 expression and function in asthmatic airway smooth muscle cells
-
Joubert P, Lajoie-Kadoch S, Labonte I, Gounni AS, Maghni K, Wellemans V, Chakir J, Laviolette M, Hamid Q, Lamkhioued B. CCR3 expression and function in asthmatic airway smooth muscle cells. J Immunol 2005;175:2702-2708.
-
(2005)
J Immunol
, vol.175
, pp. 2702-2708
-
-
Joubert, P.1
Lajoie-Kadoch, S.2
Labonte, I.3
Gounni, A.S.4
Maghni, K.5
Wellemans, V.6
Chakir, J.7
Laviolette, M.8
Hamid, Q.9
Lamkhioued, B.10
-
13
-
-
33845519705
-
Airway smooth muscle and mast cellderived CC chemokine ligand 19 mediate airway smooth muscle migration in asthma
-
Kaur D, Saunders R, Berger P, Siddiqui S, Woodman L, Wardlaw A, Bradding P, Brightling CE. Airway smooth muscle and mast cellderived CC chemokine ligand 19 mediate airway smooth muscle migration in asthma. Am J Respir Crit Care Med 2006;174: 1179-1188.
-
(2006)
Am J Respir Crit Care Med
, vol.174
, pp. 1179-1188
-
-
Kaur, D.1
Saunders, R.2
Berger, P.3
Siddiqui, S.4
Woodman, L.5
Wardlaw, A.6
Bradding, P.7
Brightling, C.E.8
-
14
-
-
34047143642
-
Increased expression of ADAM33 and ADAM8 with disease progression in asthma
-
Foley SC, Mogas AK, Olivenstein R, Fiset PO, Chakir J, Bourbeau J, Ernst P, Lemiere C, Martin JG, Hamid Q. Increased expression of ADAM33 and ADAM8 with disease progression in asthma. J Allergy Clin Immunol 2007;119:863-871.
-
(2007)
J Allergy Clin Immunol
, vol.119
, pp. 863-871
-
-
Foley, S.C.1
Mogas, A.K.2
Olivenstein, R.3
Fiset, P.O.4
Chakir, J.5
Bourbeau, J.6
Ernst, P.7
Lemiere, C.8
Martin, J.G.9
Hamid, Q.10
-
15
-
-
33645280327
-
A disintegrin and metalloproteinase 33 protein in patients with asthma: Relevance to airflow limitation
-
Lee JY, Park SW, Chang HK, Kim HY, Rhim T, Lee JH, Jang AS, Koh ES, Park CS. A disintegrin and metalloproteinase 33 protein in patients with asthma: Relevance to airflow limitation. Am J Respir Crit Care Med 2006;173:729-735.
-
(2006)
Am J Respir Crit Care Med
, vol.173
, pp. 729-735
-
-
Lee, J.Y.1
Park, S.W.2
Chang, H.K.3
Kim, H.Y.4
Rhim, T.5
Lee, J.H.6
Jang, A.S.7
Koh, E.S.8
Park, C.S.9
-
16
-
-
27644492383
-
A fully dissociated compound of plant origin for inflammatory gene repression
-
De Bosscher K, Vanden Berghe W, Beck IME, Van Molle W, Hennuyer N, Hapgood J, Libert C, Staels B, Louw A, Haegeman G. A fully dissociated compound of plant origin for inflammatory gene repression. Proc Natl Acad Sci USA 2005;102:15827-15832.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 15827-15832
-
-
De Bosscher, K.1
Vanden, B.W.2
Beck, I.M.E.3
Van Molle, W.4
Hennuyer, N.5
Hapgood, J.6
Libert, C.7
Staels, B.8
Louw, A.9
Haegeman, G.10
-
17
-
-
70349247894
-
Compound A, a plant origin ligand of glucocorticoid receptors, increases regulatory T cells and M2 macrophages to attenuate experimental autoimmune neuritis with reduced side effects
-
Zhang Z, Zhang ZY, Schluesener HJ. Compound A, a plant origin ligand of glucocorticoid receptors, increases regulatory T cells and M2 macrophages to attenuate experimental autoimmune neuritis with reduced side effects. J Immunol 2009;183:3081-3091.
-
(2009)
J Immunol
, vol.183
, pp. 3081-3091
-
-
Zhang, Z.1
Zhang, Z.Y.2
Schluesener, H.J.3
-
18
-
-
40849142555
-
A plant-derived ligand favoring monomeric glucocorticoid receptor conformation with impaired transactivation potential attenuates collagen-induced arthritis
-
Dewint P, Gossye V, De Bosscher K, Vanden Berghe W, Van Beneden K, Deforce D, Van Calenbergh S, Muller-Ladner U, Vander Cruyssen B, Verbruggen G, et al. A plant-derived ligand favoring monomeric glucocorticoid receptor conformation with impaired transactivation potential attenuates collagen-induced arthritis. J Immunol 2008;180: 2608-2615.
-
(2008)
J Immunol
, vol.180
, pp. 2608-2615
-
-
Dewint, P.1
Gossye, V.2
De Bosscher, K.3
Vanden, B.W.4
Van, B.K.5
Deforce, D.6
Van, C.S.7
Muller-Ladner, U.8
Vander Cruyssen, B.9
Verbruggen, G.10
-
19
-
-
75149156175
-
Antiinflammatory properties of a plant-derived nonsteroidal, dissociated glucocorticoid receptor modulator in experimental autoimmune encephalomyelitis
-
van Loo G, Sze M, Bougarne N, Praet J, Mc Guire C, Ullrich A, Haegeman G, Prinz M, Beyaert R, De Bosscher K. Antiinflammatory properties of a plant-derived nonsteroidal, dissociated glucocorticoid receptor modulator in experimental autoimmune encephalomyelitis. Mol Endocrinol 2010;24:310-322.
-
(2010)
Mol Endocrinol
, vol.24
, pp. 310-322
-
-
Van Loo, G.1
Sze, M.2
Bougarne, N.3
Praet, J.4
Mc Guire, C.5
Ullrich, A.6
Haegeman, G.7
Prinz, M.8
Beyaert, R.9
De Bosscher, K.10
-
20
-
-
77949524864
-
Therapeutic and adverse effects of a non-steroidal glucocorticoid receptor ligand in a mouse model of multiple sclerosis
-
Wust S, Tischner D, John M, Tuckermann JP, Menzfeld C, Hanisch UK, van den Brandt J, Luhder F, Reichardt HM. Therapeutic and adverse effects of a non-steroidal glucocorticoid receptor ligand in a mouse model of multiple sclerosis. PLoS One 2009;4:e8202.
-
(2009)
PLoS One
, vol.4
, pp. e8202
-
-
Wust, S.1
Tischner, D.2
John, M.3
Tuckermann, J.P.4
Menzfeld, C.5
Hanisch, U.K.6
Van Den Brandt, J.7
Luhder, F.8
Reichardt, H.M.9
-
21
-
-
79954592084
-
An antiinflammatory selective glucocorticoid receptor modulator preserves osteoblast differentiation
-
Rauch A, Gossye V, Bracke D, Gevaert E, Jacques P, VanBeneden K, Vandooren B, Rauner M, Hofbauer LC, Haegeman G, et al. An antiinflammatory selective glucocorticoid receptor modulator preserves osteoblast differentiation. FASEB J 2011;25:1323-1332.
-
(2011)
FASEB J
, vol.25
, pp. 1323-1332
-
-
Rauch, A.1
Gossye, V.2
Bracke, D.3
Gevaert, E.4
Jacques, P.5
Van Beneden, K.6
Vandooren, B.7
Rauner, M.8
Hofbauer, L.C.9
Haegeman, G.10
-
22
-
-
84859390611
-
A dissociated glucocorticoid receptor modulator reduces airway hyperresponsiveness and inflammation in a mouse model of asthma
-
Reber LL, Daubeuf F, Plantinga M, De Cauwer L, Gerlo S, Waelput W, Van Calenbergh S, Tavernier J, Haegeman G, Lambrecht BN, et al. A dissociated glucocorticoid receptor modulator reduces airway hyperresponsiveness and inflammation in a mouse model of asthma. J Immunol 2012;188:3478-3487.
-
(2012)
J Immunol
, vol.188
, pp. 3478-3487
-
-
Reber, L.L.1
Daubeuf, F.2
Plantinga, M.3
De Cauwer, L.4
Gerlo, S.5
Waelput, W.6
Van, C.S.7
Tavernier, J.8
Haegeman, G.9
Lambrecht, B.N.10
-
23
-
-
84883336417
-
Functional KCa3.1 channels regulate steroid insensitivity in bronchial smooth muscle cells
-
Chachi L, Shikotra A, Duffy SM, Tliba O, Brightling C, Bradding P, Amrani Y. Functional KCa3.1 channels regulate steroid insensitivity in bronchial smooth muscle cells. J Immunol 2013;191:2624-2636.
-
(2013)
J Immunol
, vol.191
, pp. 2624-2636
-
-
Chachi, L.1
Shikotra, A.2
Duffy, S.M.3
Tliba, O.4
Brightling, C.5
Bradding, P.6
Amrani, Y.7
-
24
-
-
18644380441
-
The CXCL10/CXCR3 axis mediates human lung mast cell migration to asthmatic airway smooth muscle
-
Brightling CE, Ammit AJ, Kaur D, Black JL, Wardlaw AJ, Hughes JM, Bradding P. The CXCL10/CXCR3 axis mediates human lung mast cell migration to asthmatic airway smooth muscle. Am J Respir Crit Care Med 2005;171:1103-1108.
-
(2005)
Am J Respir Crit Care Med
, vol.171
, pp. 1103-1108
-
-
Brightling, C.E.1
Ammit, A.J.2
Kaur, D.3
Black, J.L.4
Wardlaw, A.J.5
Hughes, J.M.6
Bradding, P.7
-
25
-
-
41449101856
-
Cytokines induce an early steroid resistance in airway smooth muscle cells: Novel role of interferon regulatory factor-1
-
Tliba O, Damera G, Banerjee A, Gu S, Baidouri H, Keslacy S, Amrani Y. Cytokines induce an early steroid resistance in airway smooth muscle cells: novel role of interferon regulatory factor-1. Am J Respir Cell Mol Biol 2008;38:463-472.
-
(2008)
Am J Respir Cell Mol Biol
, vol.38
, pp. 463-472
-
-
Tliba, O.1
Damera, G.2
Banerjee, A.3
Gu, S.4
Baidouri, H.5
Keslacy, S.6
Amrani, Y.7
-
26
-
-
84864507046
-
Sphingosine 1-phosphate induces MKP-1 expression via p38 MAPK- And CREB-mediated pathways in airway smooth muscle cells
-
Che W, Manetsch M, Quante T, Rahman MM, Patel BS, Ge Q, Ammit AJ. Sphingosine 1-phosphate induces MKP-1 expression via p38 MAPK- And CREB-mediated pathways in airway smooth muscle cells. Biochim Biophys Acta 2012;1823:1658-1665.
-
(2012)
Biochim Biophys Acta
, vol.1823
, pp. 1658-1665
-
-
Che, W.1
Manetsch, M.2
Quante, T.3
Rahman, M.M.4
Patel, B.S.5
Ge, Q.6
Ammit, A.J.7
-
27
-
-
34547883918
-
Anti-inflammatory functions of glucocorticoid-induced genes
-
Clark AR. Anti-inflammatory functions of glucocorticoid-induced genes. Mol Cell Endocrinol 2007;275:79-97.
-
(2007)
Mol Cell Endocrinol
, vol.275
, pp. 79-97
-
-
Clark, A.R.1
-
28
-
-
77950892860
-
Abrogation of glucocorticoid receptor dimerization correlates with dissociated glucocorticoid behavior of Compound A
-
Robertson S, Allie-Reid F, Vanden Berghe W, Visser K, Binder A, Africander D, Vismer M, De Bosscher K, Hapgood J, Haegeman G, et al. Abrogation of glucocorticoid receptor dimerization correlates with dissociated glucocorticoid behavior of Compound a. J Biol Chem 2010;285:8061-8075.
-
(2010)
J Biol Chem
, vol.285
, pp. 8061-8075
-
-
Robertson, S.1
Allie-Reid, F.2
Vanden, B.W.3
Visser, K.4
Binder, A.5
Africander, D.6
Vismer, M.7
De Bosscher, K.8
Hapgood, J.9
Haegeman, G.10
-
29
-
-
31044434618
-
CD38 expression is insensitive to steroid action in cells treated with tumor necrosis factor-alpha and interferon-gamma by a mechanism involving the up-regulation of the glucocorticoid receptor beta isoform
-
Tliba O, Cidlowski JA, Amrani Y. CD38 expression is insensitive to steroid action in cells treated with tumor necrosis factor-alpha and interferon-gamma by a mechanism involving the up-regulation of the glucocorticoid receptor beta isoform. Mol Pharmacol 2006;69: 588-596.
-
(2006)
Mol Pharmacol
, vol.69
, pp. 588-596
-
-
Tliba, O.1
Cidlowski, J.A.2
Amrani, Y.3
-
30
-
-
0036009461
-
Tumor necrosis factor-alpha-induced secretion of RANTES and interleukin-6 from human airway smooth muscle cells: Modulation by glucocorticoids and beta-agonists
-
Ammit AJ, Lazaar AL, Irani C, O'Neill GM, Gordon ND, Amrani Y, Penn RB, Panettieri RA Jr. Tumor necrosis factor-alpha-induced secretion of RANTES and interleukin-6 from human airway smooth muscle cells: modulation by glucocorticoids and beta-agonists. Am J Respir Cell Mol Biol 2002;26:465-474.
-
(2002)
Am J Respir Cell Mol Biol
, vol.26
, pp. 465-474
-
-
Ammit, A.J.1
Lazaar, A.L.2
Irani, C.3
O'Neill, G.M.4
Gordon, N.D.5
Amrani, Y.6
Penn, R.B.7
Panettieri, R.A.8
-
31
-
-
48649103130
-
Corticosteroids reduce IL-6 in ASM cells via upregulation of MKP-1
-
Quante T, Ng YC, Ramsay EE, Henness S, Allen JC, Parmentier J, Ge Q, Ammit AJ. Corticosteroids reduce IL-6 in ASM cells via upregulation of MKP-1. Am J Respir Cell Mol Biol 2008;39:208-217.
-
(2008)
Am J Respir Cell Mol Biol
, vol.39
, pp. 208-217
-
-
Quante, T.1
Ng, Y.C.2
Ramsay, E.E.3
Henness, S.4
Allen, J.C.5
Parmentier, J.6
Ge, Q.7
Ammit, A.J.8
-
32
-
-
73949127444
-
Glucocorticoid receptor interacting protein-1 restores glucocorticoid responsiveness in steroid-resistant airway structural cells
-
Bhandare R, Damera G, Banerjee A, Flammer JR, Keslacy S, Rogatsky I, Panettieri RA, Amrani Y, Tliba O. Glucocorticoid receptor interacting protein-1 restores glucocorticoid responsiveness in steroid-resistant airway structural cells. Am J Respir Cell Mol Biol 2010;42:9-15.
-
(2010)
Am J Respir Cell Mol Biol
, vol.42
, pp. 9-15
-
-
Bhandare, R.1
Damera, G.2
Banerjee, A.3
Flammer, J.R.4
Keslacy, S.5
Rogatsky, I.6
Panettieri, R.A.7
Amrani, Y.8
Tliba, O.9
-
33
-
-
84866980758
-
Cytokines alter glucocorticoid receptor phosphorylation in airway cells: Role of phosphatases
-
Bouazza B, Krytska K, Debba-Pavard M, Amrani Y, Honkanen RE, Tran J, Tliba O. Cytokines alter glucocorticoid receptor phosphorylation in airway cells: Role of phosphatases. Am J Respir Cell Mol Biol 2012;47: 464-473.
-
(2012)
Am J Respir Cell Mol Biol
, vol.47
, pp. 464-473
-
-
Bouazza, B.1
Krytska, K.2
Debba-Pavard, M.3
Amrani, Y.4
Honkanen, R.E.5
Tran, J.6
Tliba, O.7
-
34
-
-
84891883016
-
Selective modulation of the glucocorticoid receptor can distinguish between transrepression of NF-kB and AP-1
-
De Bosscher K, Beck IM, Dejager L, Bougarne N, Gaigneaux A, Chateauvieux S, Ratman D, Bracke M, Tavernier J, Vanden Berghe W, et al. Selective modulation of the glucocorticoid receptor can distinguish between transrepression of NF-kB and AP-1. Cell Mol Life Sci 2014;71:143-163.
-
(2014)
Cell Mol Life Sci
, vol.71
, pp. 143-163
-
-
De Bosscher, K.1
Beck, I.M.2
Dejager, L.3
Bougarne, N.4
Gaigneaux, A.5
Chateauvieux, S.6
Ratman, D.7
Bracke, M.8
Tavernier, J.9
Vanden, B.W.10
-
35
-
-
84856237919
-
Selective non-steroidal glucocorticoid receptor agonists attenuate inflammation but do not impair intestinal epithelial cell restitution in vitro
-
Reuter KC, Loitsch SM, Dignass AU, Steinhilber D, Stein J. Selective non-steroidal glucocorticoid receptor agonists attenuate inflammation but do not impair intestinal epithelial cell restitution in vitro. PLoS One 2012;7:e29756.
-
(2012)
PLoS One
, vol.7
, pp. e29756
-
-
Reuter, K.C.1
Loitsch, S.M.2
Dignass, A.U.3
Steinhilber, D.4
Stein, J.5
-
36
-
-
84862810230
-
MKP-1: A negative feedback effector that represses MAPK-mediated pro-inflammatory signaling pathways and cytokine secretion in human airway smooth muscle cells
-
Manetsch M, Che W, Seidel P, Chen Y, Ammit AJ. MKP-1: A negative feedback effector that represses MAPK-mediated pro-inflammatory signaling pathways and cytokine secretion in human airway smooth muscle cells. Cell Signal 2012;24:907-913.
-
(2012)
Cell Signal
, vol.24
, pp. 907-913
-
-
Manetsch, M.1
Che, W.2
Seidel, P.3
Chen, Y.4
Ammit, A.J.5
-
37
-
-
84875330999
-
Long-acting b2-agonists increase fluticasone propionate-induced mitogen-activated protein kinase phosphatase 1 (MKP-1) in airway smooth muscle cells
-
Manetsch M, Rahman MM, Patel BS, Ramsay EE, Rumzhum NN, Alkhouri H, Ge Q, Ammit AJ. Long-acting b2-agonists increase fluticasone propionate-induced mitogen-activated protein kinase phosphatase 1 (MKP-1) in airway smooth muscle cells. PLoS One 2013;8:e59635.
-
(2013)
PLoS One
, vol.8
, pp. e59635
-
-
Manetsch, M.1
Rahman, M.M.2
Patel, B.S.3
Ramsay, E.E.4
Rumzhum, N.N.5
Alkhouri, H.6
Ge, Q.7
Ammit, A.J.8
-
38
-
-
78650850288
-
Dissociation of osteogenic and immunological effects by the selective glucocorticoid receptor agonist, compound A, in human bone marrow stromal cells
-
Rauner M, Goettsch C, Stein N, Thiele S, Bornhaeuser M, De Bosscher K, Haegeman G, Tuckermann J, Hofbauer LC. Dissociation of osteogenic and immunological effects by the selective glucocorticoid receptor agonist, compound A, in human bone marrow stromal cells. Endocrinology 2011;152:103-112.
-
(2011)
Endocrinology
, vol.152
, pp. 103-112
-
-
Rauner, M.1
Goettsch, C.2
Stein, N.3
Thiele, S.4
Bornhaeuser, M.5
De Bosscher, K.6
Haegeman, G.7
Tuckermann, J.8
Hofbauer, L.C.9
-
39
-
-
84859494247
-
Compound A, a dissociated glucocorticoid receptor modulator, inhibits T-bet (Th1) and induces GATA-3 (Th2) activity in immune cells
-
Liberman AC, Antunica-Noguerol M, Ferraz-de-Paula V, Palermo- Neto J, Castro CN, Druker J, Holsboer F, Perone MJ, Gerlo S, De Bosscher K, et al. Compound A, a dissociated glucocorticoid receptor modulator, inhibits T-bet (Th1) and induces GATA-3 (Th2) activity in immune cells. PLoS One 2012;7:e35155.
-
(2012)
PLoS One
, vol.7
, pp. e35155
-
-
Liberman, A.C.1
Antunica-Noguerol, M.2
Ferraz-De-Paula, V.3
Palermo-, N.J.4
Castro, C.N.5
Druker, J.6
Holsboer, F.7
Perone, M.J.8
Gerlo, S.9
De Bosscher, K.10
-
40
-
-
84872307569
-
Combination of a selective activator of the glucocorticoid receptor compound a with a proteasome inhibitor as a novel strategy for chemotherapy of hematologic malignancies
-
Lesovaya E, Yemelyanov A, Kirsanov K, Popa A, Belitsky G, Yakubovskaya M, Gordon LI, Rosen ST, Budunova I. Combination of a selective activator of the glucocorticoid receptor compound a with a proteasome inhibitor as a novel strategy for chemotherapy of hematologic malignancies. Cell Cycle 2013;12:133-144.
-
(2013)
Cell Cycle
, vol.12
, pp. 133-144
-
-
Lesovaya, E.1
Yemelyanov, A.2
Kirsanov, K.3
Popa, A.4
Belitsky, G.5
Yakubovskaya, M.6
Gordon, L.I.7
Rosen, S.T.8
Budunova, I.9
-
41
-
-
82455219494
-
Antitumor effect of non-steroid glucocorticoid receptor ligand CpdA on leukemia cell lines CEM and K562
-
Lesovaya EA, Yemelyanov AY, Kirsanov KI, Yakubovskaya MG, Budunova IV. Antitumor effect of non-steroid glucocorticoid receptor ligand CpdA on leukemia cell lines CEM and K562. Biochemistry (Mosc) 2011;76:1242-1252.
-
(2011)
Biochemistry (Mosc)
, vol.76
, pp. 1242-1252
-
-
Lesovaya, E.A.1
Yemelyanov, A.Y.2
Kirsanov, K.I.3
Yakubovskaya, M.G.4
Budunova, I.V.5
-
42
-
-
84856091925
-
Regulation of CCL5 expression in smooth muscle cells following arterial injury
-
Liu H, Ning H, Men H, Hou R, Fu M, Zhang H, Liu J. Regulation of CCL5 expression in smooth muscle cells following arterial injury. PLoS One 2012;7:e30873.
-
(2012)
PLoS One
, vol.7
, pp. e30873
-
-
Liu, H.1
Ning, H.2
Men, H.3
Hou, R.4
Fu, M.5
Zhang, H.6
Liu, J.7
-
43
-
-
78049489350
-
Lysophosphatidic acid inhibits CC chemokine ligand 5/RANTES production by blocking IRF-1-mediated gene transcription in human bronchial epithelial cells
-
Matsuzaki S, Ishizuka T, Hisada T, Aoki H, Komachi M, Ichimonji I, Utsugi M, Ono A, Koga Y, Dobashi K, et al. Lysophosphatidic acid inhibits CC chemokine ligand 5/RANTES production by blocking IRF-1-mediated gene transcription in human bronchial epithelial cells. J Immunol 2010;185:4863-4872.
-
(2010)
J Immunol
, vol.185
, pp. 4863-4872
-
-
Matsuzaki, S.1
Ishizuka, T.2
Hisada, T.3
Aoki, H.4
Komachi, M.5
Ichimonji, I.6
Utsugi, M.7
Ono, A.8
Koga, Y.9
Dobashi, K.10
-
44
-
-
77952753340
-
Characterization of synergistic induction of CX3CL1/fractalkine by TNF-alpha and IFN-gamma in vascular endothelial cells: An essential role for TNF-alpha in post-transcriptional regulation of CX3CL1
-
Matsumiya T, Ota K, Imaizumi T, Yoshida H, Kimura H, Satoh K. Characterization of synergistic induction of CX3CL1/fractalkine by TNF-alpha and IFN-gamma in vascular endothelial cells: An essential role for TNF-alpha in post-transcriptional regulation of CX3CL1. J Immunol 2010;184:4205-4214.
-
(2010)
J Immunol
, vol.184
, pp. 4205-4214
-
-
Matsumiya, T.1
Ota, K.2
Imaizumi, T.3
Yoshida, H.4
Kimura, H.5
Satoh, K.6
-
45
-
-
84895525011
-
Transcriptional and epigenetic modulation of human rhinovirus-induced CXCL10 production by cigarette smoke
-
Hudy MH, Traves SL, Proud D. Transcriptional and epigenetic modulation of human rhinovirus-induced CXCL10 production by cigarette smoke. Am J Respir Cell Mol Biol 2014;50:571-582.
-
(2014)
Am J Respir Cell Mol Biol
, vol.50
, pp. 571-582
-
-
Hudy, M.H.1
Traves, S.L.2
Proud, D.3
-
46
-
-
0042829252
-
Interferon regulatory factor-1 down-regulates cytokine-induced IP-10 expression in pancreatic islets
-
Baker MS, Chen X, Rotramel AR, Nelson JJ, Kaufman DB. Interferon regulatory factor-1 down-regulates cytokine-induced IP-10 expression in pancreatic islets. Surgery 2003;134: 134-141.
-
(2003)
Surgery
, vol.134
, pp. 134-141
-
-
Baker, M.S.1
Chen, X.2
Rotramel, A.R.3
Nelson, J.J.4
Kaufman, D.B.5
-
47
-
-
84861175829
-
Asthmatic airway smooth muscle CXCL10 production: Mitogen-activated protein kinase JNK involvement
-
Alrashdan YA, Alkhouri H, Chen E, Lalor DJ, Poniris M, Henness S, Brightling CE, Burgess JK, Armour CL, Ammit AJ, et al. Asthmatic airway smooth muscle CXCL10 production: mitogen-activated protein kinase JNK involvement. Am J Physiol Lung Cell Mol Physiol 2012;302:L1118-L1127.
-
(2012)
Am J Physiol Lung Cell Mol Physiol
, vol.302
, pp. L1118-L1127
-
-
Alrashdan, Y.A.1
Alkhouri, H.2
Chen, E.3
Lalor, D.J.4
Poniris, M.5
Henness, S.6
Brightling, C.E.7
Burgess, J.K.8
Armour, C.L.9
Ammit, A.J.10
-
48
-
-
77956547990
-
TNFa and IFNg synergistically enhance transcriptional activation of CXCL10 in human airway smooth muscle cells via STAT-1, NF-kB, and the transcriptional coactivator CREB-binding protein
-
Clarke DL, Clifford RL, Jindarat S, Proud D, Pang L, Belvisi M, Knox AJ. TNFa and IFNg synergistically enhance transcriptional activation of CXCL10 in human airway smooth muscle cells via STAT-1, NF-kB, and the transcriptional coactivator CREB-binding protein. J Biol Chem 2010;285:29101-29110.
-
(2010)
J Biol Chem
, vol.285
, pp. 29101-29110
-
-
Clarke, D.L.1
Clifford, R.L.2
Jindarat, S.3
Proud, D.4
Pang, L.5
Belvisi, M.6
Knox, A.J.7
-
49
-
-
1342310784
-
Regulation of TNF-alpha and IFN-gamma-induced CXCL10 expression: Participation of the airway smooth muscle in the pulmonary inflammatory response in chronic obstructive pulmonary disease
-
Hardaker EL, Bacon AM, Carlson K, Roshak AK, Foley JJ, Schmidt DB, Buckley PT, Comegys M, Panettieri J, Reynold A., et al. Regulation of TNF-alpha and IFN-gamma-induced CXCL10 expression: participation of the airway smooth muscle in the pulmonary inflammatory response in chronic obstructive pulmonary disease. FASEB J 2003:18:191-193.
-
(2003)
FASEB J
, vol.18
, pp. 191-193
-
-
Hardaker, E.L.1
Bacon, A.M.2
Carlson, K.3
Roshak, A.K.4
Foley, J.J.5
Schmidt, D.B.6
Buckley, P.T.7
Comegys, M.8
Panettieri, J.9
Reynold, A.10
-
50
-
-
0033135134
-
Constitutive activation of an epithelial signal transducer and activator of transcription (STAT) pathway in asthma
-
Sampath D, Castro M, Look D, Holtzman M. Constitutive activation of an epithelial signal transducer and activator of transcription (STAT) pathway in asthma. J Clin Invest 1999;103:1353-1356.
-
(1999)
J Clin Invest
, vol.103
, pp. 1353-1356
-
-
Sampath, D.1
Castro, M.2
Look, D.3
Holtzman, M.4
-
51
-
-
0035090628
-
Association of IFN-gamma and IFN regulatory factor 1 polymorphisms with childhood atopic asthma
-
Nakao F, Ihara K, Kusuhara K, Sasaki Y, Kinukawa N, Takabayashi A, Nishima S, Hara T. Association of IFN-gamma and IFN regulatory factor 1 polymorphisms with childhood atopic asthma. J Allergy Clin Immunol 2001;107:499-504.
-
(2001)
J Allergy Clin Immunol
, vol.107
, pp. 499-504
-
-
Nakao, F.1
Ihara, K.2
Kusuhara, K.3
Sasaki, Y.4
Kinukawa, N.5
Takabayashi, A.6
Nishima, S.7
Hara, T.8
-
52
-
-
40949137893
-
IRF-1 gene variations influence IgE regulation and atopy
-
Schedel M, Pinto LA, Schaub B, Rosenstiel P, Cherkasov D, Cameron L, Klopp N, Illig T, Vogelberg C, Weiland SK, et al. IRF-1 gene variations influence IgE regulation and atopy. Am J Respir Crit Care Med 2008;177:613-621.
-
(2008)
Am J Respir Crit Care Med
, vol.177
, pp. 613-621
-
-
Schedel, M.1
Pinto, L.A.2
Schaub, B.3
Rosenstiel, P.4
Cherkasov, D.5
Cameron, L.6
Klopp, N.7
Illig, T.8
Vogelberg, C.9
Weiland, S.K.10
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