Cutting the Gordian Knot: Identifiability of anaplerotic reactions in Corynebacterium glutamicum by means of 13C-metabolic flux analysis

Biotechnology and Bioengineering

Volumn 113, Issue 3, 2016, Pages 661-674

  Kappelmann, Jannick ^a   Wiechert, Wolfgang ^a   Noack, Stephan ^a  

^a FORSCHUNGSZENTRUM JÜLICH   (Germany)

Author keywords

13C metabolic flux analysis; Anaplerosis; C. glutamicum; Flux observability; Metabolic fluxes; Structural identifiability

Indexed keywords

ISOMERS; ISOTOPES; METABOLISM; REACTION RATES; TOPOLOGY;

ANAPLEROSIS; C. GLUTAMICUM; METABOLIC FLUX; METABOLIC FLUX ANALYSIS; STRUCTURAL IDENTIFIABILITY;

REACTION INTERMEDIATES;

CORYNEBACTERIUM GLUTAMICUM; GENE DELETION; METABOLIC FLUX ANALYSIS; MODEL; STRESS; METABOLISM;

AMINO ACID; CARBON; CARBOXYLIC ACID;

AMINO ACIDS; CARBON ISOTOPES; CARBOXYLIC ACIDS; CORYNEBACTERIUM GLUTAMICUM; METABOLIC FLUX ANALYSIS; METABOLIC NETWORKS AND PATHWAYS;

EID: 84955701469     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.25833     Document Type: Article

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