Identification of a mammalian glycerol-3-phosphate phosphatase: Role in metabolism and signaling in pancreatic β-cells and hepatocytes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 4, 2016, Pages E430-E439

  Mugabo, Yves ^a   Zhao, Shangang ^a   Seifried, Annegrit ^b   Gezzar, Sari ^a   Al Mass, Anfal ^a,c   Zhang, Dongwei ^a,d   Lamontagne, Julien ^a   Attane, Camille ^a   Poursharifi, Pegah ^a   Iglesias, José ^a,e   Joly, Erik ^a   Peyot, Marie Line ^a   Gohla, Antje ^b   Madiraju, S R Murthy ^a   Prentki, Marc ^a  

^a CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c MCGILL UNIVERSITY   (Canada)

^d BEIJING UNIVERSITY OF CHINESE MEDICINE   (China)

^e PONTIFICIA UNIVERSIDAD JAVERIANA   (Colombia)

Author keywords

Glucolipotoxicity; Gluconeogenesis; Glucose stimulated insulin secretion; Glycerol 3 phosphate phosphatase; Type 2 diabetes

Indexed keywords

ADENOSINE TRIPHOSPHATE; GLUCOSE; GLYCEROLIPID; GLYCEROPHOSPHATE; HIGH DENSITY LIPOPROTEIN; ALPHA-GLYCEROPHOSPHORIC ACID; FATTY ACID; GLYCEROL; INSULIN; LACTONE; MITOCHONDRIAL PROTEIN; PHOSPHATASE; PHOSPHOGLYCOLATE PHOSPHATASE; TETRAHYDROLIPSTATIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FATTY ACID OXIDATION; GLUCONEOGENESIS; GLUCOSE OXIDATION; GLYCOLYSIS; IN VITRO STUDY; IN VIVO STUDY; INSULIN RELEASE; INTRACELLULAR SIGNALING; LIPID METABOLISM; LIPOGENESIS; LIPOPROTEIN BLOOD LEVEL; LIVER CELL; MALE; MAMMAL; METABOLIC STRESS; MITOCHONDRIAL RESPIRATION; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; WEIGHT GAIN; AMINO ACID SEQUENCE; ANIMAL; ANTAGONISTS AND INHIBITORS; CARBOHYDRATE METABOLISM; CELL LINE; COMPARATIVE STUDY; DRUG EFFECTS; ENZYMOLOGY; GENETICS; HYDROLYSIS; LIVER MITOCHONDRION; METABOLISM; MOLECULAR GENETICS; MOUSE; NUTRITIONAL STATUS; PHYSIOLOGICAL STRESS; PHYSIOLOGY; RNA INTERFERENCE; SECRETION (PROCESS); SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; CARBOHYDRATE METABOLISM; CELL LINE; FATTY ACIDS; GLYCEROL; GLYCEROPHOSPHATES; HEPATOCYTES; HYDROLYSIS; INSULIN; INSULIN-SECRETING CELLS; LACTONES; LIPID METABOLISM; MALE; MICE; MITOCHONDRIA, LIVER; MITOCHONDRIAL PROTEINS; MOLECULAR SEQUENCE DATA; NUTRITIONAL STATUS; PHOSPHORIC MONOESTER HYDROLASES; RATS; RNA INTERFERENCE; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL;

EID: 84955594885     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1514375113     Document Type: Article

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