AMPKα1 controls hepatocyte proliferation independently of energy balance by regulating Cyclin A2 expression

Journal of Hepatology

Volumn 60, Issue 1, 2014, Pages 152-159

  Merlen, Grégory ^a,b,c   Gentric, Géraldine ^a,b,c   Celton Morizur, Séverine ^a,b,c   Foretz, Marc ^a,b,c   Guidotti, Jacques Emmanuel ^a,b,c   Fauveau, Véronique ^a,b,c   Leclerc, Jocelyne ^a,b,c   Viollet, Benoit ^a,b,c   Desdouets, Chantal ^a,b,c  

^a INSTITUT COCHIN   (France)

^b CNRS   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

AMPK; Cyclin A2; G1 S transition; Hapatocytes; Liver regeneration

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR; AMP ACTIVATED PROTEIN KINASE ALPHA1; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLIN A2; FAT DROPLET; GROWTH FACTOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MESSENGER RNA; UNCLASSIFIED DRUG; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE ALPHA 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CYCLE; CELL CYCLE S PHASE; CELL DIVISION; CELL PROLIFERATION; CONTROLLED STUDY; ENERGY BALANCE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; G1 PHASE CELL CYCLE CHECKPOINT; GENE DELETION; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL; LIVER CELL CULTURE; LIVER INJURY; LIVER REGENERATION; MOUSE; NONHUMAN; PARTIAL HEPATECTOMY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN METABOLISM; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WILD TYPE; ANIMAL MODEL; ANTIGEN EXPRESSION; ENZYME PHOSPHORYLATION;

AMP-ACTIVATED PROTEIN KINASE; AMPK; BRDU; BROMODEOXYURIDINE; CALMODULIN DEPENDENT PROTEIN KINASE KINASE; CAMKK; CAMP RESPONSE ELEMENT; CRE; CYCLIN A2; EGF; EPIDERMAL GROWTH FACTOR; G1/S TRANSITION; HAPATOCYTES; HEPATOCYTE GROWTH FACTOR; HGF; HUMAN-ANTIGEN R; HUR; IL-6; INTERLEUKIN-6; KNOCK-OUT; KO; LIVER KINASE B1; LIVER REGENERATION; LKB1; NITRIC OXIDE SYNTHASE; NOS; PARTIAL HEPATECTOMY; PH; PHH3; PHOSPHATIDYLINOSITOL 3-KINASE; PHOSPHO-HISTONE H3; PI3K; REACTIVE OXIGEN SPECIES; ROS; S-ADENOSYLMETHIONINE; SAME; SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION; STAT; WILD TYPE; WT;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; CELL PROLIFERATION; CYCLIN A2; ENERGY METABOLISM; HEPATOCYTES; LIVER REGENERATION; MICE; MICE, INBRED C57BL; S PHASE;

EID: 84890550990     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2013.08.025     Document Type: Article

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