메뉴 건너뛰기




Volumn 29, Issue 1, 2016, Pages 3-18

In Vitro Systems Toxicology Assessment of a Candidate Modified Risk Tobacco Product Shows Reduced Toxicity Compared to That of a Conventional Cigarette

Author keywords

[No Author keywords available]

Indexed keywords

AEROSOL; SMOKE;

EID: 84955508349     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/acs.chemrestox.5b00321     Document Type: Article
Times cited : (69)

References (62)
  • 1
    • 84893235639 scopus 로고    scopus 로고
    • U.S. Department of Health and Human Services, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health, Atlanta, GA
    • (2014) The Health Consequences of Smoking: 50 Years of Progress: A Report of the Surgeon General, U.S. Department of Health and Human Services, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health, Atlanta, GA.
    • (2014) The Health Consequences of Smoking: 50 Years of Progress: A Report of the Surgeon General
  • 3
    • 0345005991 scopus 로고
    • Temperature distribution inside a burning cigarette
    • Baker, R. R. (1974) Temperature distribution inside a burning cigarette Nature 247, 405-406 10.1038/247405a0
    • (1974) Nature , vol.247 , pp. 405-406
    • Baker, R.R.1
  • 8
    • 38849107498 scopus 로고    scopus 로고
    • Reversible and permanent effects of tobacco smoke exposure on airway epithelial gene expression
    • Beane, J., Sebastiani, P., Liu, G., Brody, J. S., Lenburg, M. E., and Spira, A. (2007) Reversible and permanent effects of tobacco smoke exposure on airway epithelial gene expression Genome Biol. 8, R201 10.1186/gb-2007-8-9-r201
    • (2007) Genome Biol. , vol.8 , pp. R201
    • Beane, J.1    Sebastiani, P.2    Liu, G.3    Brody, J.S.4    Lenburg, M.E.5    Spira, A.6
  • 10
    • 34547755693 scopus 로고    scopus 로고
    • Determination of 10 carcinogenic polycyclic aromatic hydrocarbons in mainstream cigarette smoke
    • Ding, Y. S., Ashley, D. L., and Watson, C. H. (2007) Determination of 10 carcinogenic polycyclic aromatic hydrocarbons in mainstream cigarette smoke J. Agric. Food Chem. 55, 5966-5973 10.1021/jf070649o
    • (2007) J. Agric. Food Chem. , vol.55 , pp. 5966-5973
    • Ding, Y.S.1    Ashley, D.L.2    Watson, C.H.3
  • 11
  • 12
    • 33244473082 scopus 로고    scopus 로고
    • Determination of toxic carbonyl compounds in cigarette smoke
    • Fujioka, K. and Shibamoto, T. (2006) Determination of toxic carbonyl compounds in cigarette smoke Environ. Toxicol. 21, 47-54 10.1002/tox.20153
    • (2006) Environ. Toxicol. , vol.21 , pp. 47-54
    • Fujioka, K.1    Shibamoto, T.2
  • 14
    • 84890428113 scopus 로고    scopus 로고
    • The contribution of heavy metals in cigarette smoke condensate to malignant transformation of breast epithelial cells and in vivo initiation of neoplasia through induction of a PI3K-AKT-NFkappaB cascade
    • Mohapatra, P., Preet, R., Das, D., Satapathy, S. R., Siddharth, S., Choudhuri, T., Wyatt, M. D., and Kundu, C. N. (2014) The contribution of heavy metals in cigarette smoke condensate to malignant transformation of breast epithelial cells and in vivo initiation of neoplasia through induction of a PI3K-AKT-NFkappaB cascade Toxicol. Appl. Pharmacol. 274, 168-179 10.1016/j.taap.2013.09.028
    • (2014) Toxicol. Appl. Pharmacol. , vol.274 , pp. 168-179
    • Mohapatra, P.1    Preet, R.2    Das, D.3    Satapathy, S.R.4    Siddharth, S.5    Choudhuri, T.6    Wyatt, M.D.7    Kundu, C.N.8
  • 15
    • 84898620442 scopus 로고    scopus 로고
    • Toxic metal concentrations in mainstream smoke from cigarettes available in the USA
    • Pappas, R. S., Fresquez, M. R., Martone, N., and Watson, C. H. (2014) Toxic metal concentrations in mainstream smoke from cigarettes available in the USA J. Anal. Toxicol. 38, 204-211 10.1093/jat/bku013
    • (2014) J. Anal. Toxicol. , vol.38 , pp. 204-211
    • Pappas, R.S.1    Fresquez, M.R.2    Martone, N.3    Watson, C.H.4
  • 16
    • 0037063843 scopus 로고    scopus 로고
    • Effects of volatile aromatics, aldehydes, and phenols in tobacco smoke on viability and proliferation of mouse lymphocytes
    • Poirier, M., Fournier, M., Brousseau, P., and Morin, A. (2002) Effects of volatile aromatics, aldehydes, and phenols in tobacco smoke on viability and proliferation of mouse lymphocytes J. Toxicol. Environ. Health, Part A 65, 1437-1451 10.1080/00984100290071342
    • (2002) J. Toxicol. Environ. Health, Part A , vol.65 , pp. 1437-1451
    • Poirier, M.1    Fournier, M.2    Brousseau, P.3    Morin, A.4
  • 18
    • 84868342268 scopus 로고    scopus 로고
    • Reduced exposure evaluation of an Electrically Heated Cigarette Smoking System. Part 1: Non-clinical and clinical insights
    • Schorp, M. K., Tricker, A. R., and Dempsey, R. (2012) Reduced exposure evaluation of an Electrically Heated Cigarette Smoking System. Part 1: Non-clinical and clinical insights Regul. Toxicol. Pharmacol. 64 (Suppl. 1) S1-S10 10.1016/j.yrtph.2012.08.008
    • (2012) Regul. Toxicol. Pharmacol. , vol.64 , pp. S1-S10
    • Schorp, M.K.1    Tricker, A.R.2    Dempsey, R.3
  • 19
    • 77957179411 scopus 로고
    • Ninety-day inhalation study in rats, comparing smoke from cigarettes that heat tobacco with those that burn tobacco
    • Coggins, C. R., Ayres, P. H., Mosberg, A. T., Sagartz, J. W., Burger, G. T., and Hayes, A. W. (1989) Ninety-day inhalation study in rats, comparing smoke from cigarettes that heat tobacco with those that burn tobacco Toxicol. Sci. 13, 460-483 10.1093/toxsci/13.3.460
    • (1989) Toxicol. Sci. , vol.13 , pp. 460-483
    • Coggins, C.R.1    Ayres, P.H.2    Mosberg, A.T.3    Sagartz, J.W.4    Burger, G.T.5    Hayes, A.W.6
  • 20
    • 84876709598 scopus 로고    scopus 로고
    • Harmful and potentially harmful constituents in tobacco products and tobacco smoke; established list
    • Food and Drug Administration, F. (2012) Harmful and potentially harmful constituents in tobacco products and tobacco smoke; established list Fed. Regist. 77, 20034-20037
    • (2012) Fed. Regist. , vol.77 , pp. 20034-20037
    • Food and Drug Administration1
  • 22
    • 13944255788 scopus 로고    scopus 로고
    • Global gene expression analysis of human bronchial epithelial cells treated with tobacco condensates
    • Jorgensen, E. D., Dozmorov, I., Frank, M. B., Centola, M., and Albino, A. P. (2004) Global gene expression analysis of human bronchial epithelial cells treated with tobacco condensates Cell Cycle 3, 1152-1166 10.4161/cc.3.9.1078
    • (2004) Cell Cycle , vol.3 , pp. 1152-1166
    • Jorgensen, E.D.1    Dozmorov, I.2    Frank, M.B.3    Centola, M.4    Albino, A.P.5
  • 24
    • 77951565529 scopus 로고    scopus 로고
    • Effects of 10 cigarette smoke condensates on primary human airway epithelial cells by comparative gene and cytokine expression studies
    • Pickett, G., Seagrave, J., Boggs, S., Polzin, G., Richter, P., and Tesfaigzi, Y. (2010) Effects of 10 cigarette smoke condensates on primary human airway epithelial cells by comparative gene and cytokine expression studies Toxicol. Sci. 114, 79-89 10.1093/toxsci/kfp298
    • (2010) Toxicol. Sci. , vol.114 , pp. 79-89
    • Pickett, G.1    Seagrave, J.2    Boggs, S.3    Polzin, G.4    Richter, P.5    Tesfaigzi, Y.6
  • 25
    • 36249024700 scopus 로고    scopus 로고
    • Transcriptional responses to complex mixtures: a review
    • Sen, B., Mahadevan, B., and DeMarini, D. M. (2007) Transcriptional responses to complex mixtures: a review Mutat. Res., Rev. Mutat. Res. 636, 144-177 10.1016/j.mrrev.2007.08.002
    • (2007) Mutat. Res., Rev. Mutat. Res. , vol.636 , pp. 144-177
    • Sen, B.1    Mahadevan, B.2    Demarini, D.M.3
  • 26
    • 84862807164 scopus 로고    scopus 로고
    • Genetic toxicology and toxicogenomic analysis of three cigarette smoke condensates in vitro reveals few differences among full-flavor, blonde, and light products
    • Yauk, C. L., Williams, A., Buick, J. K., Chen, G., Maertens, R. M., Halappanavar, S., and White, P. A. (2012) Genetic toxicology and toxicogenomic analysis of three cigarette smoke condensates in vitro reveals few differences among full-flavor, blonde, and light products Environ. Mol. Mutagen. 53, 281-296 10.1002/em.21689
    • (2012) Environ. Mol. Mutagen. , vol.53 , pp. 281-296
    • Yauk, C.L.1    Williams, A.2    Buick, J.K.3    Chen, G.4    Maertens, R.M.5    Halappanavar, S.6    White, P.A.7
  • 34
    • 0021078674 scopus 로고
    • Differential control by platelet factors of squamous differentiation in normal and malignant human bronchial epithelial cells
    • Lechner, J. F., McClendon, I. A., LaVeck, M. A., Shamsuddin, A. M., and Harris, C. C. (1983) Differential control by platelet factors of squamous differentiation in normal and malignant human bronchial epithelial cells Cancer Res. 43, 5915-5921
    • (1983) Cancer Res. , vol.43 , pp. 5915-5921
    • Lechner, J.F.1    McClendon, I.A.2    Laveck, M.A.3    Shamsuddin, A.M.4    Harris, C.C.5
  • 35
    • 84955480942 scopus 로고    scopus 로고
    • High Content Screening Analysis to Evaluate the Toxicological Effects of Harmful and Potentially Harmful Constituents (HPHC)
    • In press
    • Marescotti, D., Gonzalez Suarez, I., Acali, S., Johne, S., Laurent, A., Frentzel, S., Hoeng, J., and Peitsch, M. High Content Screening Analysis To Evaluate The Toxicological Effects Of Harmful And Potentially Harmful Constituents (HPHC). J. Vis. Exp. 2015, In press
    • (2015) J. Vis. Exp.
    • Marescotti, D.1    Gonzalez Suarez, I.2    Acali, S.3    Johne, S.4    Laurent, A.5    Frentzel, S.6    Hoeng, J.7    Peitsch, M.8
  • 37
    • 77749291770 scopus 로고    scopus 로고
    • Frozen robust multiarray analysis (fRMA)
    • McCall, M. N., Bolstad, B. M., and Irizarry, R. A. (2010) Frozen robust multiarray analysis (fRMA) Biostatistics 11, 242-253 10.1093/biostatistics/kxp059
    • (2010) Biostatistics , vol.11 , pp. 242-253
    • McCall, M.N.1    Bolstad, B.M.2    Irizarry, R.A.3
  • 39
    • 0037316303 scopus 로고    scopus 로고
    • A comparison of normalization methods for high density oligonucleotide array data based on variance and bias
    • Bolstad, B. M., Irizarry, R. A., Astrand, M., and Speed, T. P. (2003) A comparison of normalization methods for high density oligonucleotide array data based on variance and bias Bioinformatics 19, 185-193 10.1093/bioinformatics/19.2.185
    • (2003) Bioinformatics , vol.19 , pp. 185-193
    • Bolstad, B.M.1    Irizarry, R.A.2    Astrand, M.3    Speed, T.P.4
  • 40
    • 1342288026 scopus 로고    scopus 로고
    • Affy - Analysis of Affymetrix GeneChip data at the probe level
    • Gautier, L., Cope, L., Bolstad, B. M., and Irizarry, R. A. (2004) affy - analysis of Affymetrix GeneChip data at the probe level Bioinformatics 20, 307-315 10.1093/bioinformatics/btg405
    • (2004) Bioinformatics , vol.20 , pp. 307-315
    • Gautier, L.1    Cope, L.2    Bolstad, B.M.3    Irizarry, R.A.4
  • 41
    • 4544341015 scopus 로고    scopus 로고
    • Linear models and empirical bayes methods for assessing differential expression in microarray experiments
    • Smyth, G. K. (2004) Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat. Appl. Genet. Mol. Biol. 3, 1 10.2202/1544-6115.1027
    • (2004) Stat. Appl. Genet. Mol. Biol. , vol.3 , pp. 1
    • Smyth, G.K.1
  • 49
    • 84904074764 scopus 로고    scopus 로고
    • Quantification of biological network perturbations for mechanistic insight and diagnostics using two-layer causal models
    • Martin, F., Sewer, A., Talikka, M., Xiang, Y., Hoeng, J., and Peitsch, M. C. (2014) Quantification of biological network perturbations for mechanistic insight and diagnostics using two-layer causal models BMC Bioinf. 15, 238 10.1186/1471-2105-15-238
    • (2014) BMC Bioinf. , vol.15 , pp. 238
    • Martin, F.1    Sewer, A.2    Talikka, M.3    Xiang, Y.4    Hoeng, J.5    Peitsch, M.C.6
  • 52
    • 13444273546 scopus 로고    scopus 로고
    • DNA repair: the importance of phosphorylating histone H2AX
    • Lowndes, N. F. and Toh, G. W. (2005) DNA repair: the importance of phosphorylating histone H2AX Curr. Biol. 15, R99-R102 10.1016/j.cub.2005.01.029
    • (2005) Curr. Biol. , vol.15 , pp. R99-R102
    • Lowndes, N.F.1    Toh, G.W.2
  • 53
    • 84945479517 scopus 로고    scopus 로고
    • Biological Impact of Cigarette Smoke compared to an Aerosol produced from a Prototypic Modified Risk Tobacco Product on Normal Human Bronchial Epithelial Cells
    • Kogel, U., Gonzalez Suarez, I., Xiang, Y., Dossin, E., Guy, P. A., Mathis, C., Marescotti, D., Goedertier, D., Martin, F., Peitsch, M. C., and Hoeng, J. (2015) Biological Impact of Cigarette Smoke compared to an Aerosol produced from a Prototypic Modified Risk Tobacco Product on Normal Human Bronchial Epithelial Cells Toxicol. In Vitro 29, 2102-2115 10.1016/j.tiv.2015.08.004
    • (2015) Toxicol. in Vitro , vol.29 , pp. 2102-2115
    • Kogel, U.1    Gonzalez Suarez, I.2    Xiang, Y.3    Dossin, E.4    Guy, P.A.5    Mathis, C.6    Marescotti, D.7    Goedertier, D.8    Martin, F.9    Peitsch, M.C.10    Hoeng, J.11
  • 54
    • 0141592290 scopus 로고    scopus 로고
    • Toxicological evaluation of an electrically heated cigarette. Part 1: Overview of technical concepts and summary of findings
    • Patskan, G. and Reininghaus, W. (2003) Toxicological evaluation of an electrically heated cigarette. Part 1: Overview of technical concepts and summary of findings J. Appl. Toxicol. 23, 323-328 10.1002/jat.923
    • (2003) J. Appl. Toxicol. , vol.23 , pp. 323-328
    • Patskan, G.1    Reininghaus, W.2
  • 55
    • 27244431824 scopus 로고    scopus 로고
    • Oxidative stress, cell death, and other damage to alveolar epithelial cells induced by cigarette smoke
    • Aoshiba, K. and Nagai, A. (2003) Oxidative stress, cell death, and other damage to alveolar epithelial cells induced by cigarette smoke Tob. Induced Dis. 1, 219-226 10.1186/1617-9625-1-3-219
    • (2003) Tob. Induced Dis. , vol.1 , pp. 219-226
    • Aoshiba, K.1    Nagai, A.2
  • 57
    • 84866398376 scopus 로고    scopus 로고
    • Nrf2: friend and foe in preventing cigarette smoking-dependent lung disease
    • Muller, T. and Hengstermann, A. (2012) Nrf2: friend and foe in preventing cigarette smoking-dependent lung disease Chem. Res. Toxicol. 25, 1805-1824 10.1021/tx300145n
    • (2012) Chem. Res. Toxicol. , vol.25 , pp. 1805-1824
    • Muller, T.1    Hengstermann, A.2
  • 59
    • 70349495882 scopus 로고    scopus 로고
    • DNA damage response induced by tobacco smoke in normal human bronchial epithelial and A549 pulmonary adenocarcinoma cells assessed by laser scanning cytometry
    • Zhao, H., Albino, A. P., Jorgensen, E., Traganos, F., and Darzynkiewicz, Z. (2009) DNA damage response induced by tobacco smoke in normal human bronchial epithelial and A549 pulmonary adenocarcinoma cells assessed by laser scanning cytometry Cytometry, Part A 75, 840-847 10.1002/cyto.a.20778
    • (2009) Cytometry, Part A , vol.75 , pp. 840-847
    • Zhao, H.1    Albino, A.P.2    Jorgensen, E.3    Traganos, F.4    Darzynkiewicz, Z.5
  • 61
    • 84940404091 scopus 로고    scopus 로고
    • Impaired mitophagy leads to cigarette smoke stress-induced cellular senescence: implications for chronic obstructive pulmonary disease
    • Ahmad, T., Sundar, I. K., Lerner, C. A., Gerloff, J., Tormos, A. M., Yao, H., and Rahman, I. (2015) Impaired mitophagy leads to cigarette smoke stress-induced cellular senescence: implications for chronic obstructive pulmonary disease FASEB J. 29, 2912-2929 10.1096/fj.14-268276
    • (2015) FASEB J. , vol.29 , pp. 2912-2929
    • Ahmad, T.1    Sundar, I.K.2    Lerner, C.A.3    Gerloff, J.4    Tormos, A.M.5    Yao, H.6    Rahman, I.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.