Systems biology approach for evaluating the biological impact of environmental toxicants in vitro

Chemical Research in Toxicology

Volumn 27, Issue 3, 2014, Pages 367-376

  Gonzalez Suarez, Ignacio ^a   Sewer, Alain ^a   Walker, Paul ^b   Mathis, Carole ^a   Ellis, Samantha ^b   Woodhouse, Heather ^b   Guedj, Emmanuel ^a   Dulize, Remi ^a   Marescotti, Diego ^a   Acali, Stefano ^a   Martin, Florian ^a   Ivanov, Nikolai V ^a   Hoeng, Julia ^a   Peitsch, Manuel C ^a  

^a PHILIP MORRIS PRODUCTS S A   (Switzerland)

^b CYPROTEX DISCOVERY LTD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACROLEIN; CASPASE 3; CASPASE 7; CATECHOL; CIGARETTE SMOKE; CYTOCHROME C; FORMALDEHYDE; GLUTATHIONE; HISTONE H2AX; LACTATE DEHYDROGENASE; REACTIVE OXYGEN METABOLITE; TOBACCO SMOKE;

ARTICLE; BRONCHUS MUCOSA; CELL CYCLE ARREST; CELL STRESS; CYTOTOXICITY; DNA DAMAGE; DNA STRUCTURE; ENVIRONMENTAL EXPOSURE; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; IN VITRO STUDY; MEMBRANE PERMEABILITY; MICROARRAY ANALYSIS; MITOCHONDRIAL MEMBRANE POTENTIAL; OXIDATIVE STRESS; PROTEIN PHOSPHORYLATION; RISK ASSESSMENT; SYSTEMS BIOLOGY; TRANSCRIPTOMICS;

ACROLEIN; APOPTOSIS; CATECHOLS; CELL PROLIFERATION; CELLS, CULTURED; DNA DAMAGE; EPITHELIAL CELLS; FORMALDEHYDE; GENE EXPRESSION PROFILING; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; REACTIVE OXYGEN SPECIES; SMOKE;

EID: 84896364353     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx400405s     Document Type: Article

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