-
1
-
-
77955889782
-
Relationship between environmental exposures in children and adult lung disease: the case for outdoor exposures
-
10.1177/1479972309345929, 19819910
-
Soto-Martinez M, Sly PD. Relationship between environmental exposures in children and adult lung disease: the case for outdoor exposures. Chron Respir Dis 2010, 7:173-186. 10.1177/1479972309345929, 19819910.
-
(2010)
Chron Respir Dis
, vol.7
, pp. 173-186
-
-
Soto-Martinez, M.1
Sly, P.D.2
-
2
-
-
34548838308
-
U.S. EPA health assessment for diesel engine exhaust: a review
-
Ris C. U.S. EPA health assessment for diesel engine exhaust: a review. Inhal Toxicol 2007, 19(Suppl 1):229-239.
-
(2007)
Inhal Toxicol
, vol.19
, Issue.SUPPL. 1
, pp. 229-239
-
-
Ris, C.1
-
3
-
-
3042719079
-
Effects of cigarette smoke on the human airway epithelial cell transcriptome
-
10.1073/pnas.0401422101, 454179, 15210990
-
Spira A, Beane J, Shah V, Liu G, Schembri F, Yang X, Palma J, Brody JS. Effects of cigarette smoke on the human airway epithelial cell transcriptome. Proc Natl Acad Sci USA 2004, 101:10143-10148. 10.1073/pnas.0401422101, 454179, 15210990.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 10143-10148
-
-
Spira, A.1
Beane, J.2
Shah, V.3
Liu, G.4
Schembri, F.5
Yang, X.6
Palma, J.7
Brody, J.S.8
-
4
-
-
61749088394
-
The field of tissue injury in the lung and airway
-
Steiling K, Ryan J, Brody JS, Spira A. The field of tissue injury in the lung and airway. Cancer Prev Res (Phila) 2008, 1:396-403.
-
(2008)
Cancer Prev Res (Phila)
, vol.1
, pp. 396-403
-
-
Steiling, K.1
Ryan, J.2
Brody, J.S.3
Spira, A.4
-
5
-
-
56849114813
-
Environmental risk factors for heart disease
-
10.1515/REVEH.2008.23.3.167, 19119685
-
O'Toole TE, Conklin DJ, Bhatnagar A. Environmental risk factors for heart disease. Rev Environ Health 2008, 23:167-202. 10.1515/REVEH.2008.23.3.167, 19119685.
-
(2008)
Rev Environ Health
, vol.23
, pp. 167-202
-
-
O'Toole, T.E.1
Conklin, D.J.2
Bhatnagar, A.3
-
6
-
-
77957867918
-
Endothelin-1 as a potential marker of melatonin's therapeutic effects in smoking-induced vasculopathy
-
10.1016/j.lfs.2010.09.011, 20854829
-
Rodella LF, Favero G, Rossini C, Foglio E, Reiter RJ, Rezzani R. Endothelin-1 as a potential marker of melatonin's therapeutic effects in smoking-induced vasculopathy. Life Sci 2010, 87:558-564. 10.1016/j.lfs.2010.09.011, 20854829.
-
(2010)
Life Sci
, vol.87
, pp. 558-564
-
-
Rodella, L.F.1
Favero, G.2
Rossini, C.3
Foglio, E.4
Reiter, R.J.5
Rezzani, R.6
-
7
-
-
64749084472
-
Peroxynitrite as regulator of vascular prostanoid synthesis
-
10.1016/j.abb.2008.10.023, 18983814
-
Schildknecht S, Ullrich V. Peroxynitrite as regulator of vascular prostanoid synthesis. Arch Biochem Biophys 2009, 484:183-189. 10.1016/j.abb.2008.10.023, 18983814.
-
(2009)
Arch Biochem Biophys
, vol.484
, pp. 183-189
-
-
Schildknecht, S.1
Ullrich, V.2
-
8
-
-
72149118185
-
Residential traffic exposure and coronary heart disease: results from the Heinz Nixdorf Recall Study
-
Hoffmann B, Moebus S, Dragano N, Mohlenkamp S, Memmesheimer M, Erbel R, Jockel KH. Residential traffic exposure and coronary heart disease: results from the Heinz Nixdorf Recall Study. Biomarkers 2009, 14(Suppl 1):74-78.
-
(2009)
Biomarkers
, vol.14
, Issue.SUPPL. 1
, pp. 74-78
-
-
Hoffmann, B.1
Moebus, S.2
Dragano, N.3
Mohlenkamp, S.4
Memmesheimer, M.5
Erbel, R.6
Jockel, K.H.7
-
9
-
-
34548821633
-
Mortality effects of longer term exposures to fine particulate air pollution: review of recent epidemiological evidence
-
Pope CA. Mortality effects of longer term exposures to fine particulate air pollution: review of recent epidemiological evidence. Inhal Toxicol 2007, 19(Suppl 1):33-38.
-
(2007)
Inhal Toxicol
, vol.19
, Issue.SUPPL. 1
, pp. 33-38
-
-
Pope, C.A.1
-
10
-
-
23644440662
-
Mortality and long-term exposure to ambient air pollution: ongoing analyses based on the American Cancer Society cohort
-
10.1080/15287390590935941, 16024490
-
Krewski D, Burnett R, Jerrett M, Pope CA, Rainham D, Calle E, Thurston G, Thun M. Mortality and long-term exposure to ambient air pollution: ongoing analyses based on the American Cancer Society cohort. J Toxicol Environ Health A 2005, 68:1093-1109. 10.1080/15287390590935941, 16024490.
-
(2005)
J Toxicol Environ Health A
, vol.68
, pp. 1093-1109
-
-
Krewski, D.1
Burnett, R.2
Jerrett, M.3
Pope, C.A.4
Rainham, D.5
Calle, E.6
Thurston, G.7
Thun, M.8
-
11
-
-
36248985688
-
Air pollution combustion emissions: characterization of causative agents and mechanisms associated with cancer, reproductive, and cardiovascular effects
-
10.1016/j.mrrev.2007.08.003, 17951105
-
Lewtas J. Air pollution combustion emissions: characterization of causative agents and mechanisms associated with cancer, reproductive, and cardiovascular effects. Mutat Res 2007, 636:95-133. 10.1016/j.mrrev.2007.08.003, 17951105.
-
(2007)
Mutat Res
, vol.636
, pp. 95-133
-
-
Lewtas, J.1
-
12
-
-
77956246433
-
Acute effects of motor vehicle traffic-related air pollution exposures on measures of oxidative stress in human airways
-
10.1111/j.1749-6632.2010.05604.x, 20716291
-
Laumbach RJ, Kipen HM. Acute effects of motor vehicle traffic-related air pollution exposures on measures of oxidative stress in human airways. Ann N Y Acad Sci 2010, 1203:107-112. 10.1111/j.1749-6632.2010.05604.x, 20716291.
-
(2010)
Ann N Y Acad Sci
, vol.1203
, pp. 107-112
-
-
Laumbach, R.J.1
Kipen, H.M.2
-
13
-
-
50949106154
-
Cardiovascular effects of air pollution
-
Brook RD. Cardiovascular effects of air pollution. Clin Sci (Lond) 2008, 115:175-187.
-
(2008)
Clin Sci (Lond)
, vol.115
, pp. 175-187
-
-
Brook, R.D.1
-
14
-
-
30544438454
-
Air pollution: from lung to heart
-
Kunzli N, Tager IB. Air pollution: from lung to heart. Swiss Med Wkly 2005, 135:697-702.
-
(2005)
Swiss Med Wkly
, vol.135
, pp. 697-702
-
-
Kunzli, N.1
Tager, I.B.2
-
15
-
-
50949117527
-
Network inference algorithms elucidate Nrf2 regulation of mouse lung oxidative stress
-
10.1371/journal.pcbi.1000166, 2516606, 18769717
-
Taylor RC, Acquaah-Mensah G, Singhal M, Malhotra D, Biswal S. Network inference algorithms elucidate Nrf2 regulation of mouse lung oxidative stress. PLoS Comput Biol 2008, 4:e1000166. 10.1371/journal.pcbi.1000166, 2516606, 18769717.
-
(2008)
PLoS Comput Biol
, vol.4
-
-
Taylor, R.C.1
Acquaah-Mensah, G.2
Singhal, M.3
Malhotra, D.4
Biswal, S.5
-
16
-
-
74249101956
-
Delineation of a gene network underlying the pulmonary response to oxidative stress in asthma
-
Freishtat RJ, Benton AS, Watson AM, Wang Z, Rose MC, Hoffman EP. Delineation of a gene network underlying the pulmonary response to oxidative stress in asthma. J Investig Med 2009, 57:756-764.
-
(2009)
J Investig Med
, vol.57
, pp. 756-764
-
-
Freishtat, R.J.1
Benton, A.S.2
Watson, A.M.3
Wang, Z.4
Rose, M.C.5
Hoffman, E.P.6
-
17
-
-
77953681096
-
A systems biology approach to understanding atherosclerosis
-
10.1002/emmm.201000063, 2992755, 20201031
-
Ramsey SA, Gold ES, Aderem A. A systems biology approach to understanding atherosclerosis. EMBO Mol Med 2010, 2:79-89. 10.1002/emmm.201000063, 2992755, 20201031.
-
(2010)
EMBO Mol Med
, vol.2
, pp. 79-89
-
-
Ramsey, S.A.1
Gold, E.S.2
Aderem, A.3
-
18
-
-
75749119678
-
The use of network analyses for elucidating mechanisms in cardiovascular disease
-
10.1039/b912078e, 20094647
-
Diez D, Wheelock AM, Goto S, Haeggstrom JZ, Paulsson-Berne G, Hansson GK, Hedin U, Gabrielsen A, Wheelock CE. The use of network analyses for elucidating mechanisms in cardiovascular disease. Mol Biosyst 2010, 6:289-304. 10.1039/b912078e, 20094647.
-
(2010)
Mol Biosyst
, vol.6
, pp. 289-304
-
-
Diez, D.1
Wheelock, A.M.2
Goto, S.3
Haeggstrom, J.Z.4
Paulsson-Berne, G.5
Hansson, G.K.6
Hedin, U.7
Gabrielsen, A.8
Wheelock, C.E.9
-
19
-
-
65949121177
-
Systems biology approaches and pathway tools for investigating cardiovascular disease
-
10.1039/b902356a, 19462016
-
Wheelock CE, Wheelock AM, Kawashima S, Diez D, Kanehisa M, van Erk M, Kleemann R, Haeggstrom JZ, Goto S. Systems biology approaches and pathway tools for investigating cardiovascular disease. Mol Biosyst 2009, 5:588-602. 10.1039/b902356a, 19462016.
-
(2009)
Mol Biosyst
, vol.5
, pp. 588-602
-
-
Wheelock, C.E.1
Wheelock, A.M.2
Kawashima, S.3
Diez, D.4
Kanehisa, M.5
van Erk, M.6
Kleemann, R.7
Haeggstrom, J.Z.8
Goto, S.9
-
20
-
-
60849113126
-
Transcriptional network classifiers
-
10.1186/1471-2105-10-S9-S1, 20151484
-
Chang HH, Ramoni MF. Transcriptional network classifiers. BMC Bioinformatics 2009, 10(Suppl 9):S1. 10.1186/1471-2105-10-S9-S1, 20151484.
-
(2009)
BMC Bioinformatics
, vol.10
, Issue.SUPPL. 9
-
-
Chang, H.H.1
Ramoni, M.F.2
-
21
-
-
79959759890
-
Construction of a computable cell proliferation network focused on non-diseased lung cells
-
10.1186/1752-0509-5-105, 3160372, 21722388
-
Westra JW, Schlage WK, Frushour BP, Gebel S, Catlett NL, Han W, Eddy SF, Hengstermann A, Matthews AL, Mathis C, et al. Construction of a computable cell proliferation network focused on non-diseased lung cells. BMC Syst Biol 2011, 5:105. 10.1186/1752-0509-5-105, 3160372, 21722388.
-
(2011)
BMC Syst Biol
, vol.5
, pp. 105
-
-
Westra, J.W.1
Schlage, W.K.2
Frushour, B.P.3
Gebel, S.4
Catlett, N.L.5
Han, W.6
Eddy, S.F.7
Hengstermann, A.8
Matthews, A.L.9
Mathis, C.10
-
22
-
-
77649273792
-
Nrf2 protects against airway disorders
-
10.1016/j.taap.2009.07.024, 19646463
-
Cho HY, Kleeberger SR. Nrf2 protects against airway disorders. Toxicol Appl Pharmacol 2010, 244:43-56. 10.1016/j.taap.2009.07.024, 19646463.
-
(2010)
Toxicol Appl Pharmacol
, vol.244
, pp. 43-56
-
-
Cho, H.Y.1
Kleeberger, S.R.2
-
23
-
-
33644649131
-
Nrf2 defends the lung from oxidative stress
-
10.1089/ars.2006.8.76, 16487040
-
Cho HY, Reddy SP, Kleeberger SR. Nrf2 defends the lung from oxidative stress. Antioxid Redox Signal 2006, 8:76-87. 10.1089/ars.2006.8.76, 16487040.
-
(2006)
Antioxid Redox Signal
, vol.8
, pp. 76-87
-
-
Cho, H.Y.1
Reddy, S.P.2
Kleeberger, S.R.3
-
24
-
-
33646698196
-
Current concepts of redox signaling in the lungs
-
10.1089/ars.2006.8.681, 16677111
-
Rahman I, Yang SR, Biswas SK. Current concepts of redox signaling in the lungs. Antioxid Redox Signal 2006, 8:681-689. 10.1089/ars.2006.8.681, 16677111.
-
(2006)
Antioxid Redox Signal
, vol.8
, pp. 681-689
-
-
Rahman, I.1
Yang, S.R.2
Biswas, S.K.3
-
25
-
-
84885685207
-
Reverse Causal Reasoning Methods Whitepaper
-
Reverse Causal Reasoning Methods Whitepaper. , http://www.selventa.com/technology/white-papers
-
-
-
-
26
-
-
34047188665
-
Computational causal reasoning models of mechanisms of androgen stimulation in prostate cancer
-
Pratt D, Hahn W, Matthews A, Febbo P, Berger R, Duckworth B, Levy J, Segaran T, Sun J, Ladd B, Elliston K. Computational causal reasoning models of mechanisms of androgen stimulation in prostate cancer. Conf Proc IEEE Eng Med Biol Soc 2006, 1:38.
-
(2006)
Conf Proc IEEE Eng Med Biol Soc
, vol.1
, pp. 38
-
-
Pratt, D.1
Hahn, W.2
Matthews, A.3
Febbo, P.4
Berger, R.5
Duckworth, B.6
Levy, J.7
Segaran, T.8
Sun, J.9
Ladd, B.10
Elliston, K.11
-
27
-
-
58149360793
-
SIRT1 promotes differentiation of normal human keratinocytes
-
10.1038/jid.2008.179, 18563176
-
Blander G, Bhimavarapu A, Mammone T, Maes D, Elliston K, Reich C, Matsui MS, Guarente L, Loureiro JJ. SIRT1 promotes differentiation of normal human keratinocytes. J Invest Dermatol 2009, 129:41-49. 10.1038/jid.2008.179, 18563176.
-
(2009)
J Invest Dermatol
, vol.129
, pp. 41-49
-
-
Blander, G.1
Bhimavarapu, A.2
Mammone, T.3
Maes, D.4
Elliston, K.5
Reich, C.6
Matsui, M.S.7
Guarente, L.8
Loureiro, J.J.9
-
28
-
-
34347223660
-
Epitope-driven TB vaccine development: a streamlined approach using immuno-informatics, ELISpot assays, and HLA transgenic mice
-
10.2174/156652407780831584, 17584075
-
McMurry JA, Kimball S, Lee JH, Rivera D, Martin W, Weiner DB, Kutzler M, Sherman DR, Kornfeld H, De Groot AS. Epitope-driven TB vaccine development: a streamlined approach using immuno-informatics, ELISpot assays, and HLA transgenic mice. Curr Mol Med 2007, 7:351-368. 10.2174/156652407780831584, 17584075.
-
(2007)
Curr Mol Med
, vol.7
, pp. 351-368
-
-
McMurry, J.A.1
Kimball, S.2
Lee, J.H.3
Rivera, D.4
Martin, W.5
Weiner, D.B.6
Kutzler, M.7
Sherman, D.R.8
Kornfeld, H.9
De Groot, A.S.10
-
29
-
-
79952708723
-
Endoplasmic reticulum stress in liver disease
-
10.1016/j.jhep.2010.11.005, 21145844
-
Malhi H, Kaufman RJ. Endoplasmic reticulum stress in liver disease. J Hepatol 2011, 54:795-809. 10.1016/j.jhep.2010.11.005, 21145844.
-
(2011)
J Hepatol
, vol.54
, pp. 795-809
-
-
Malhi, H.1
Kaufman, R.J.2
-
30
-
-
79953788716
-
The transcriptome of Nrf2-/- mice provides evidence for impaired cell cycle progression in the development of cigarette smoke-induced emphysematous changes
-
10.1093/toxsci/kfq039, 20133372
-
Gebel S, Diehl S, Pype J, Friedrichs B, Weiler H, Schuller J, Xu H, Taguchi K, Yamamoto M, Muller T. The transcriptome of Nrf2-/- mice provides evidence for impaired cell cycle progression in the development of cigarette smoke-induced emphysematous changes. Toxicol Sci 2010, 115:238-252. 10.1093/toxsci/kfq039, 20133372.
-
(2010)
Toxicol Sci
, vol.115
, pp. 238-252
-
-
Gebel, S.1
Diehl, S.2
Pype, J.3
Friedrichs, B.4
Weiler, H.5
Schuller, J.6
Xu, H.7
Taguchi, K.8
Yamamoto, M.9
Muller, T.10
-
31
-
-
77649273272
-
Nrf2 the rescue: effects of the antioxidative/electrophilic response on the liver
-
10.1016/j.taap.2010.01.013, 2860427, 20122946
-
Klaassen CD, Reisman SA. Nrf2 the rescue: effects of the antioxidative/electrophilic response on the liver. Toxicol Appl Pharmacol 2010, 244:57-65. 10.1016/j.taap.2010.01.013, 2860427, 20122946.
-
(2010)
Toxicol Appl Pharmacol
, vol.244
, pp. 57-65
-
-
Klaassen, C.D.1
Reisman, S.A.2
-
32
-
-
7244253081
-
Nrf2-Keap1 defines a physiologically important stress response mechanism
-
10.1016/j.molmed.2004.09.003, 15519281
-
Motohashi H, Yamamoto M. Nrf2-Keap1 defines a physiologically important stress response mechanism. Trends Mol Med 2004, 10:549-557. 10.1016/j.molmed.2004.09.003, 15519281.
-
(2004)
Trends Mol Med
, vol.10
, pp. 549-557
-
-
Motohashi, H.1
Yamamoto, M.2
-
33
-
-
0033920261
-
ATF6 as a transcription activator of the endoplasmic reticulum stress element: thapsigargin stress-induced changes and synergistic interactions with NF-Y and YY1
-
10.1128/MCB.20.14.5096-5106.2000, 85959, 10866666
-
Li M, Baumeister P, Roy B, Phan T, Foti D, Luo S, Lee AS. ATF6 as a transcription activator of the endoplasmic reticulum stress element: thapsigargin stress-induced changes and synergistic interactions with NF-Y and YY1. Mol Cell Biol 2000, 20:5096-5106. 10.1128/MCB.20.14.5096-5106.2000, 85959, 10866666.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 5096-5106
-
-
Li, M.1
Baumeister, P.2
Roy, B.3
Phan, T.4
Foti, D.5
Luo, S.6
Lee, A.S.7
-
34
-
-
33344469643
-
Oxidative and electrophilic stresses activate Nrf2 through inhibition of ubiquitination activity of Keap1
-
10.1128/MCB.26.1.221-229.2006, 1317630, 16354693
-
Kobayashi A, Kang MI, Watai Y, Tong KI, Shibata T, Uchida K, Yamamoto M. Oxidative and electrophilic stresses activate Nrf2 through inhibition of ubiquitination activity of Keap1. Mol Cell Biol 2006, 26:221-229. 10.1128/MCB.26.1.221-229.2006, 1317630, 16354693.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 221-229
-
-
Kobayashi, A.1
Kang, M.I.2
Watai, Y.3
Tong, K.I.4
Shibata, T.5
Uchida, K.6
Yamamoto, M.7
-
35
-
-
0347481377
-
Deficiency of the Nrf1 and Nrf2 transcription factors results in early embryonic lethality and severe oxidative stress
-
10.1074/jbc.M308439200, 12968018
-
Leung L, Kwong M, Hou S, Lee C, Chan JY. Deficiency of the Nrf1 and Nrf2 transcription factors results in early embryonic lethality and severe oxidative stress. J Biol Chem 2003, 278:48021-48029. 10.1074/jbc.M308439200, 12968018.
-
(2003)
J Biol Chem
, vol.278
, pp. 48021-48029
-
-
Leung, L.1
Kwong, M.2
Hou, S.3
Lee, C.4
Chan, J.Y.5
-
36
-
-
85050781204
-
Protective effects of adiponectin against renal ischemia-reperfusion injury via prostacyclin -PPARalpha- heme oxygenase-1 signaling pathway
-
Cheng CF, Lian WS, Chen SH, Lai PF, Li HF, Lan YF, Cheng WT, Lin H. Protective effects of adiponectin against renal ischemia-reperfusion injury via prostacyclin -PPARalpha- heme oxygenase-1 signaling pathway. J Cell Physiol 2010,
-
(2010)
J Cell Physiol
-
-
Cheng, C.F.1
Lian, W.S.2
Chen, S.H.3
Lai, P.F.4
Li, H.F.5
Lan, Y.F.6
Cheng, W.T.7
Lin, H.8
-
37
-
-
50949089166
-
NF-kappaB and AP-1 are key signaling pathways in the modulation of NAD(P)H:quinone oxidoreductase 1 gene by mercury, lead, and copper
-
10.1002/jbt.20238, 18752316
-
Korashy HM, El-Kadi AO. NF-kappaB and AP-1 are key signaling pathways in the modulation of NAD(P)H:quinone oxidoreductase 1 gene by mercury, lead, and copper. J Biochem Mol Toxicol 2008, 22:274-283. 10.1002/jbt.20238, 18752316.
-
(2008)
J Biochem Mol Toxicol
, vol.22
, pp. 274-283
-
-
Korashy, H.M.1
El-Kadi, A.O.2
-
38
-
-
67449168081
-
Disruption of Nrf2 impairs the resolution of hyperoxia-induced acute lung injury and inflammation in mice
-
10.4049/jimmunol.0804248, 2820248, 19454723
-
Reddy NM, Kleeberger SR, Kensler TW, Yamamoto M, Hassoun PM, Reddy SP. Disruption of Nrf2 impairs the resolution of hyperoxia-induced acute lung injury and inflammation in mice. J Immunol 2009, 182:7264-7271. 10.4049/jimmunol.0804248, 2820248, 19454723.
-
(2009)
J Immunol
, vol.182
, pp. 7264-7271
-
-
Reddy, N.M.1
Kleeberger, S.R.2
Kensler, T.W.3
Yamamoto, M.4
Hassoun, P.M.5
Reddy, S.P.6
-
39
-
-
67349214659
-
Dose-dependent transitions in Nrf2-mediated adaptive response and related stress responses to hypochlorous acid in mouse macrophages
-
10.1016/j.taap.2009.04.007, 2697450, 19376150
-
Woods CG, Fu J, Xue P, Hou Y, Pluta LJ, Yang L, Zhang Q, Thomas RS, Andersen ME, Pi J. Dose-dependent transitions in Nrf2-mediated adaptive response and related stress responses to hypochlorous acid in mouse macrophages. Toxicol Appl Pharmacol 2009, 238:27-36. 10.1016/j.taap.2009.04.007, 2697450, 19376150.
-
(2009)
Toxicol Appl Pharmacol
, vol.238
, pp. 27-36
-
-
Woods, C.G.1
Fu, J.2
Xue, P.3
Hou, Y.4
Pluta, L.J.5
Yang, L.6
Zhang, Q.7
Thomas, R.S.8
Andersen, M.E.9
Pi, J.10
-
40
-
-
41549148595
-
Identification of Nrf2-dependent airway epithelial adaptive response to proinflammatory oxidant-hypochlorous acid challenge by transcription profiling
-
Zhu L, Pi J, Wachi S, Andersen ME, Wu R, Chen Y. Identification of Nrf2-dependent airway epithelial adaptive response to proinflammatory oxidant-hypochlorous acid challenge by transcription profiling. Am J Physiol Lung Cell Mol Physiol 2008, 294:L469-477.
-
(2008)
Am J Physiol Lung Cell Mol Physiol
, vol.294
-
-
Zhu, L.1
Pi, J.2
Wachi, S.3
Andersen, M.E.4
Wu, R.5
Chen, Y.6
-
41
-
-
33750221963
-
The unfolded protein response is an important regulator of inflammatory genes in endothelial cells
-
10.1161/01.ATV.0000242903.41158.a1, 16931790
-
Gargalovic PS, Gharavi NM, Clark MJ, Pagnon J, Yang WP, He A, Truong A, Baruch-Oren T, Berliner JA, Kirchgessner TG, Lusis AJ. The unfolded protein response is an important regulator of inflammatory genes in endothelial cells. Arterioscler Thromb Vasc Biol 2006, 26:2490-2496. 10.1161/01.ATV.0000242903.41158.a1, 16931790.
-
(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, pp. 2490-2496
-
-
Gargalovic, P.S.1
Gharavi, N.M.2
Clark, M.J.3
Pagnon, J.4
Yang, W.P.5
He, A.6
Truong, A.7
Baruch-Oren, T.8
Berliner, J.A.9
Kirchgessner, T.G.10
Lusis, A.J.11
-
42
-
-
2442542312
-
PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress
-
10.1074/jbc.M314219200, 14978030
-
Cullinan SB, Diehl JA. PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress. J Biol Chem 2004, 279:20108-20117. 10.1074/jbc.M314219200, 14978030.
-
(2004)
J Biol Chem
, vol.279
, pp. 20108-20117
-
-
Cullinan, S.B.1
Diehl, J.A.2
-
43
-
-
46249090088
-
KLF2 primes the antioxidant transcription factor Nrf2 for activation in endothelial cells
-
10.1161/ATVBAHA.108.165811, 18467642
-
Fledderus JO, Boon RA, Volger OL, Hurttila H, Yla-Herttuala S, Pannekoek H, Levonen AL, Horrevoets AJ. KLF2 primes the antioxidant transcription factor Nrf2 for activation in endothelial cells. Arterioscler Thromb Vasc Biol 2008, 28:1339-1346. 10.1161/ATVBAHA.108.165811, 18467642.
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 1339-1346
-
-
Fledderus, J.O.1
Boon, R.A.2
Volger, O.L.3
Hurttila, H.4
Yla-Herttuala, S.5
Pannekoek, H.6
Levonen, A.L.7
Horrevoets, A.J.8
-
44
-
-
22844450096
-
Differential responses of the Nrf2-Keap1 system to laminar and oscillatory shear stresses in endothelial cells
-
10.1074/jbc.M502551200, 15917255
-
Hosoya T, Maruyama A, Kang MI, Kawatani Y, Shibata T, Uchida K, Warabi E, Noguchi N, Itoh K, Yamamoto M. Differential responses of the Nrf2-Keap1 system to laminar and oscillatory shear stresses in endothelial cells. J Biol Chem 2005, 280:27244-27250. 10.1074/jbc.M502551200, 15917255.
-
(2005)
J Biol Chem
, vol.280
, pp. 27244-27250
-
-
Hosoya, T.1
Maruyama, A.2
Kang, M.I.3
Kawatani, Y.4
Shibata, T.5
Uchida, K.6
Warabi, E.7
Noguchi, N.8
Itoh, K.9
Yamamoto, M.10
-
45
-
-
77952671413
-
HIF-1 alpha signaling is augmented during intermittent hypoxia by induction of the Nrf2 pathway in NOX1-expressing adenocarcinoma A549 cells
-
10.1016/j.freeradbiomed.2010.03.008, 20347035
-
Malec V, Gottschald OR, Li S, Rose F, Seeger W, Hanze J. HIF-1 alpha signaling is augmented during intermittent hypoxia by induction of the Nrf2 pathway in NOX1-expressing adenocarcinoma A549 cells. Free Radic Biol Med 2010, 48:1626-1635. 10.1016/j.freeradbiomed.2010.03.008, 20347035.
-
(2010)
Free Radic Biol Med
, vol.48
, pp. 1626-1635
-
-
Malec, V.1
Gottschald, O.R.2
Li, S.3
Rose, F.4
Seeger, W.5
Hanze, J.6
-
46
-
-
33846279783
-
Requirement of aryl hydrocarbon receptor overexpression for CYP1B1 up-regulation and cell growth in human lung adenocarcinomas
-
10.1158/1078-0432.CCR-06-1166, 17200336
-
Chang JT, Chang H, Chen PH, Lin SL, Lin P. Requirement of aryl hydrocarbon receptor overexpression for CYP1B1 up-regulation and cell growth in human lung adenocarcinomas. Clin Cancer Res 2007, 13:38-45. 10.1158/1078-0432.CCR-06-1166, 17200336.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 38-45
-
-
Chang, J.T.1
Chang, H.2
Chen, P.H.3
Lin, S.L.4
Lin, P.5
-
47
-
-
33747595955
-
Transcription factors in airway diseases
-
10.1038/labinvest.3700456, 16865089
-
Barnes PJ. Transcription factors in airway diseases. Lab Invest 2006, 86:867-872. 10.1038/labinvest.3700456, 16865089.
-
(2006)
Lab Invest
, vol.86
, pp. 867-872
-
-
Barnes, P.J.1
-
48
-
-
33646171699
-
Divergent roles of IRE1alpha and PERK in the unfolded protein response
-
10.2174/156652406775574569, 16472110
-
Schroder M, Kaufman RJ. Divergent roles of IRE1alpha and PERK in the unfolded protein response. Curr Mol Med 2006, 6:5-36. 10.2174/156652406775574569, 16472110.
-
(2006)
Curr Mol Med
, vol.6
, pp. 5-36
-
-
Schroder, M.1
Kaufman, R.J.2
-
49
-
-
80255128994
-
An Intact Canonical NF-{kappa}B Pathway Is Required for Inflammatory Gene Expression in Response to Hypoxia
-
Fitzpatrick SF, Tambuwala MM, Bruning U, Schaible B, Scholz CC, Byrne A, O'Connor A, Gallagher WM, Lenihan CR, Garvey JF, et al. An Intact Canonical NF-{kappa}B Pathway Is Required for Inflammatory Gene Expression in Response to Hypoxia. J Immunol 2010,
-
(2010)
J Immunol
-
-
Fitzpatrick, S.F.1
Tambuwala, M.M.2
Bruning, U.3
Schaible, B.4
Scholz, C.C.5
Byrne, A.6
O'Connor, A.7
Gallagher, W.M.8
Lenihan, C.R.9
Garvey, J.F.10
-
50
-
-
0031601849
-
Effects of mechanical forces on signal transduction and gene expression in endothelial cells
-
Chien S, Li S, Shyy YJ. Effects of mechanical forces on signal transduction and gene expression in endothelial cells. Hypertension 1998, 31:162-169.
-
(1998)
Hypertension
, vol.31
, pp. 162-169
-
-
Chien, S.1
Li, S.2
Shyy, Y.J.3
-
51
-
-
5344263720
-
NF-kappaB protects lung epithelium against hyperoxia-induced nonapoptotic cell death-oncosis
-
10.1016/j.freeradbiomed.2004.08.007, 15477018
-
Franek WR, Morrow DM, Zhu H, Vancurova I, Miskolci V, Darley-Usmar K, Simms HH, Mantell LL. NF-kappaB protects lung epithelium against hyperoxia-induced nonapoptotic cell death-oncosis. Free Radic Biol Med 2004, 37:1670-1679. 10.1016/j.freeradbiomed.2004.08.007, 15477018.
-
(2004)
Free Radic Biol Med
, vol.37
, pp. 1670-1679
-
-
Franek, W.R.1
Morrow, D.M.2
Zhu, H.3
Vancurova, I.4
Miskolci, V.5
Darley-Usmar, K.6
Simms, H.H.7
Mantell, L.L.8
-
52
-
-
15244356847
-
Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice
-
524225, 15520857
-
Rangasamy T, Cho CY, Thimmulappa RK, Zhen L, Srisuma SS, Kensler TW, Yamamoto M, Petrache I, Tuder RM, Biswal S. Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice. J Clin Invest 2004, 114:1248-1259. 524225, 15520857.
-
(2004)
J Clin Invest
, vol.114
, pp. 1248-1259
-
-
Rangasamy, T.1
Cho, C.Y.2
Thimmulappa, R.K.3
Zhen, L.4
Srisuma, S.S.5
Kensler, T.W.6
Yamamoto, M.7
Petrache, I.8
Tuder, R.M.9
Biswal, S.10
-
53
-
-
51049112958
-
Cigarette smoke induces endoplasmic reticulum stress and the unfolded protein response in normal and malignant human lung cells
-
10.1186/1471-2407-8-229, 2527015, 18694499
-
Jorgensen E, Stinson A, Shan L, Yang J, Gietl D, Albino AP. Cigarette smoke induces endoplasmic reticulum stress and the unfolded protein response in normal and malignant human lung cells. BMC Cancer 2008, 8:229. 10.1186/1471-2407-8-229, 2527015, 18694499.
-
(2008)
BMC Cancer
, vol.8
, pp. 229
-
-
Jorgensen, E.1
Stinson, A.2
Shan, L.3
Yang, J.4
Gietl, D.5
Albino, A.P.6
-
54
-
-
42949118737
-
Cigarette smoke induces an unfolded protein response in the human lung: a proteomic approach
-
Kelsen SG, Duan X, Ji R, Perez O, Liu C, Merali S. Cigarette smoke induces an unfolded protein response in the human lung: a proteomic approach. Am J Respir Cell Mol Biol 2008, 38:541-550.
-
(2008)
Am J Respir Cell Mol Biol
, vol.38
, pp. 541-550
-
-
Kelsen, S.G.1
Duan, X.2
Ji, R.3
Perez, O.4
Liu, C.5
Merali, S.6
-
55
-
-
39949085603
-
Endoplasmic reticulum stress induced by aqueous extracts of cigarette smoke in 3T3 cells activates the unfolded-protein-response-dependent PERK pathway of cell survival
-
10.1016/j.freeradbiomed.2007.12.009, 18206657
-
Hengstermann A, Muller T. Endoplasmic reticulum stress induced by aqueous extracts of cigarette smoke in 3T3 cells activates the unfolded-protein-response-dependent PERK pathway of cell survival. Free Radic Biol Med 2008, 44:1097-1107. 10.1016/j.freeradbiomed.2007.12.009, 18206657.
-
(2008)
Free Radic Biol Med
, vol.44
, pp. 1097-1107
-
-
Hengstermann, A.1
Muller, T.2
-
56
-
-
0035877643
-
Identification of activating transcription factor 4 (ATF4) as an Nrf2-interacting protein. Implication for heme oxygenase-1 gene regulation
-
10.1074/jbc.M101198200, 11274184
-
He CH, Gong P, Hu B, Stewart D, Choi ME, Choi AM, Alam J. Identification of activating transcription factor 4 (ATF4) as an Nrf2-interacting protein. Implication for heme oxygenase-1 gene regulation. J Biol Chem 2001, 276:20858-20865. 10.1074/jbc.M101198200, 11274184.
-
(2001)
J Biol Chem
, vol.276
, pp. 20858-20865
-
-
He, C.H.1
Gong, P.2
Hu, B.3
Stewart, D.4
Choi, M.E.5
Choi, A.M.6
Alam, J.7
-
57
-
-
9744220302
-
Cigarette smoke alters chromatin remodeling and induces proinflammatory genes in rat lungs
-
10.1165/rcmb.2004-0006OC, 15333327
-
Marwick JA, Kirkham PA, Stevenson CS, Danahay H, Giddings J, Butler K, Donaldson K, Macnee W, Rahman I. Cigarette smoke alters chromatin remodeling and induces proinflammatory genes in rat lungs. Am J Respir Cell Mol Biol 2004, 31:633-642. 10.1165/rcmb.2004-0006OC, 15333327.
-
(2004)
Am J Respir Cell Mol Biol
, vol.31
, pp. 633-642
-
-
Marwick, J.A.1
Kirkham, P.A.2
Stevenson, C.S.3
Danahay, H.4
Giddings, J.5
Butler, K.6
Donaldson, K.7
Macnee, W.8
Rahman, I.9
-
58
-
-
27944453137
-
MAPK/AP-1 signal pathway in tobacco smoke-induced cell proliferation and squamous metaplasia in the lungs of rats
-
10.1093/carcin/bgi189, 16051644
-
Zhong CY, Zhou YM, Douglas GC, Witschi H, Pinkerton KE. MAPK/AP-1 signal pathway in tobacco smoke-induced cell proliferation and squamous metaplasia in the lungs of rats. Carcinogenesis 2005, 26:2187-2195. 10.1093/carcin/bgi189, 16051644.
-
(2005)
Carcinogenesis
, vol.26
, pp. 2187-2195
-
-
Zhong, C.Y.1
Zhou, Y.M.2
Douglas, G.C.3
Witschi, H.4
Pinkerton, K.E.5
-
59
-
-
0036258689
-
Kinetics of gene expression profiling in Swiss 3T3 cells exposed to aqueous extracts of cigarette smoke
-
10.1093/carcin/23.5.741, 12016146
-
Bosio A, Knorr C, Janssen U, Gebel S, Haussmann HJ, Muller T. Kinetics of gene expression profiling in Swiss 3T3 cells exposed to aqueous extracts of cigarette smoke. Carcinogenesis 2002, 23:741-748. 10.1093/carcin/23.5.741, 12016146.
-
(2002)
Carcinogenesis
, vol.23
, pp. 741-748
-
-
Bosio, A.1
Knorr, C.2
Janssen, U.3
Gebel, S.4
Haussmann, H.J.5
Muller, T.6
-
60
-
-
3142663363
-
S-glutathiolation of Ras mediates redox-sensitive signaling by angiotensin II in vascular smooth muscle cells
-
10.1074/jbc.M313320200, 15123696
-
Adachi T, Pimentel DR, Heibeck T, Hou X, Lee YJ, Jiang B, Ido Y, Cohen RA. S-glutathiolation of Ras mediates redox-sensitive signaling by angiotensin II in vascular smooth muscle cells. J Biol Chem 2004, 279:29857-29862. 10.1074/jbc.M313320200, 15123696.
-
(2004)
J Biol Chem
, vol.279
, pp. 29857-29862
-
-
Adachi, T.1
Pimentel, D.R.2
Heibeck, T.3
Hou, X.4
Lee, Y.J.5
Jiang, B.6
Ido, Y.7
Cohen, R.A.8
-
61
-
-
0034695441
-
Reactive oxygen species activate p90 ribosomal S6 kinase via Fyn and Ras
-
10.1074/jbc.275.3.1739, 10636870
-
Abe J, Okuda M, Huang Q, Yoshizumi M, Berk BC. Reactive oxygen species activate p90 ribosomal S6 kinase via Fyn and Ras. J Biol Chem 2000, 275:1739-1748. 10.1074/jbc.275.3.1739, 10636870.
-
(2000)
J Biol Chem
, vol.275
, pp. 1739-1748
-
-
Abe, J.1
Okuda, M.2
Huang, Q.3
Yoshizumi, M.4
Berk, B.C.5
-
62
-
-
0033597766
-
Fyn and JAK2 mediate Ras activation by reactive oxygen species
-
10.1074/jbc.274.30.21003, 10409649
-
Abe J, Berk BC. Fyn and JAK2 mediate Ras activation by reactive oxygen species. J Biol Chem 1999, 274:21003-21010. 10.1074/jbc.274.30.21003, 10409649.
-
(1999)
J Biol Chem
, vol.274
, pp. 21003-21010
-
-
Abe, J.1
Berk, B.C.2
-
63
-
-
77349088313
-
Detecting disease associated modules and prioritizing active genes based on high throughput data
-
10.1186/1471-2105-11-26, 2825224, 20070902
-
Qiu YQ, Zhang S, Zhang XS, Chen L. Detecting disease associated modules and prioritizing active genes based on high throughput data. BMC Bioinformatics 2010, 11:26. 10.1186/1471-2105-11-26, 2825224, 20070902.
-
(2010)
BMC Bioinformatics
, vol.11
, pp. 26
-
-
Qiu, Y.Q.1
Zhang, S.2
Zhang, X.S.3
Chen, L.4
-
64
-
-
13244253770
-
Graph-based iterative Group Analysis enhances microarray interpretation
-
10.1186/1471-2105-5-100, 509016, 15272936
-
Breitling R, Amtmann A, Herzyk P. Graph-based iterative Group Analysis enhances microarray interpretation. BMC Bioinformatics 2004, 5:100. 10.1186/1471-2105-5-100, 509016, 15272936.
-
(2004)
BMC Bioinformatics
, vol.5
, pp. 100
-
-
Breitling, R.1
Amtmann, A.2
Herzyk, P.3
-
65
-
-
15944402798
-
Inferring pathways from gene lists using a literature-derived network of biological relationships
-
10.1093/bioinformatics/bti069, 15509611
-
Rajagopalan D, Agarwal P. Inferring pathways from gene lists using a literature-derived network of biological relationships. Bioinformatics 2005, 21:788-793. 10.1093/bioinformatics/bti069, 15509611.
-
(2005)
Bioinformatics
, vol.21
, pp. 788-793
-
-
Rajagopalan, D.1
Agarwal, P.2
-
66
-
-
35348891430
-
Network-based classification of breast cancer metastasis
-
2063581, 17940530
-
Chuang HY, Lee E, Liu YT, Lee D, Ideker T. Network-based classification of breast cancer metastasis. Mol Syst Biol 2007, 3:140. 2063581, 17940530.
-
(2007)
Mol Syst Biol
, vol.3
, pp. 140
-
-
Chuang, H.Y.1
Lee, E.2
Liu, Y.T.3
Lee, D.4
Ideker, T.5
-
67
-
-
38549088837
-
Bioinformatics and computational biology solutions using R and Bioconductor
-
Gentleman R. Bioinformatics and computational biology solutions using R and Bioconductor. Statistics for Biology and Health 2005, xix:397-420.
-
(2005)
Statistics for Biology and Health
, vol.xix
, pp. 397-420
-
-
Gentleman, R.1
-
68
-
-
28744458859
-
Bioconductor: Open software development for computational biology and bioinformatics
-
10.1186/gb-2004-5-10-r80, 545600, 15461798
-
Gentleman RC, VJC, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, et al. Bioconductor: Open software development for computational biology and bioinformatics. Genome Biology 2004, 5:R80. 10.1186/gb-2004-5-10-r80, 545600, 15461798.
-
(2004)
Genome Biology
, vol.5
-
-
Gentleman, R.C.1
Bates, D.M.2
Bolstad, B.3
Dettling, M.4
Dudoit, S.5
Ellis, B.6
Gautier, L.7
Ge, Y.8
Gentry, J.9
-
69
-
-
0142121516
-
Exploration, normalization, and summaries of high density oligonucleotide array probe level data
-
10.1093/biostatistics/4.2.249, 12925520
-
Irizarry RA, BH, Collin F, Beazer-Barclay YD, Antonellis KJ, Scherf U, Speed TP. Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 2003, 4:249-264. 10.1093/biostatistics/4.2.249, 12925520.
-
(2003)
Biostatistics
, vol.4
, pp. 249-264
-
-
Irizarry, R.A.1
Collin, F.2
Beazer-Barclay, Y.D.3
Antonellis, K.J.4
Scherf, U.5
Speed, T.P.6
-
70
-
-
33748324384
-
R: A Language and Environment for Statistical Computing
-
R Development Core Team
-
R Development Core Team R: A Language and Environment for Statistical Computing. 2007, R Development Core Team.
-
(2007)
-
-
-
71
-
-
4544341015
-
Linear models and empirical Bayes methods for assessing differential expression in microarray experiments
-
Smyth GK. Linear models and empirical Bayes methods for assessing differential expression in microarray experiments. Statistical Applications in Genetics and Molecular Biology 2004, 3:Article 3.
-
(2004)
Statistical Applications in Genetics and Molecular Biology
, vol.3
-
-
Smyth, G.K.1
|