메뉴 건너뛰기




Volumn 35, Issue 1, 2016, Pages 89-101

Gatekeeper role of brain antigen-presenting CD11c+ cells in neuroinflammation

Author keywords

chemokines; dendritic cells; EAE MS; Th17; two photon microscopy

Indexed keywords

CD11B ANTIGEN; CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR3; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CCR8; CHEMOKINE RECEPTOR CXCR1; CHEMOKINE RECEPTOR CXCR4; CXCL9 CHEMOKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GLYCOPROTEIN P 15095; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 17; L SELECTIN; RANTES; TRANSCRIPTION FACTOR FOXP3;

EID: 84955399292     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.15252/embj.201591488     Document Type: Article
Times cited : (45)

References (58)
  • 2
    • 33846472053 scopus 로고    scopus 로고
    • CNS myeloid DCs presenting endogenous myelin peptides "preferentially" polarize CD4+ T(H)-17 cells in relapsing EAE
    • Bailey SL, Schreiner B, McMahon EJ, Miller SD, (2007) CNS myeloid DCs presenting endogenous myelin peptides "preferentially" polarize CD4+ T(H)-17 cells in relapsing EAE. Nat Immunol 8: 172-180
    • (2007) Nat Immunol , vol.8 , pp. 172-180
    • Bailey, S.L.1    Schreiner, B.2    McMahon, E.J.3    Miller, S.D.4
  • 3
    • 0038523790 scopus 로고    scopus 로고
    • Myelin oligodendrocyte glycoprotein-specific T cell receptor transgenic mice develop spontaneous autoimmune optic neuritis
    • Bettelli E, Pagany M, Weiner HL, Linington C, Sobel RA, Kuchroo VK, (2003) Myelin oligodendrocyte glycoprotein-specific T cell receptor transgenic mice develop spontaneous autoimmune optic neuritis. J Exp Med 197: 1073-1081
    • (2003) J Exp Med , vol.197 , pp. 1073-1081
    • Bettelli, E.1    Pagany, M.2    Weiner, H.L.3    Linington, C.4    Sobel, R.A.5    Kuchroo, V.K.6
  • 5
    • 42649101626 scopus 로고    scopus 로고
    • Choreography of cell motility and interaction dynamics imaged by two-photon microscopy in lymphoid organs
    • Cahalan MD, Parker I, (2008) Choreography of cell motility and interaction dynamics imaged by two-photon microscopy in lymphoid organs. Annu Rev Immunol 26: 585-626
    • (2008) Annu Rev Immunol , vol.26 , pp. 585-626
    • Cahalan, M.D.1    Parker, I.2
  • 6
    • 79952143765 scopus 로고    scopus 로고
    • Cellular and molecular events in the localization of diabetogenic T cells to islets of Langerhans
    • Calderon B, Carrero JA, Miller MJ, Unanue ER, (2011) Cellular and molecular events in the localization of diabetogenic T cells to islets of Langerhans. Proc Natl Acad Sci USA 108: 1561-1566
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 1561-1566
    • Calderon, B.1    Carrero, J.A.2    Miller, M.J.3    Unanue, E.R.4
  • 7
    • 35348978611 scopus 로고    scopus 로고
    • Real-time manipulation of T cell-dendritic cell interactions in vivo reveals the importance of prolonged contacts for CD4+ T cell activation
    • Celli S, Lemaître F, Bousso P, (2007) Real-time manipulation of T cell-dendritic cell interactions in vivo reveals the importance of prolonged contacts for CD4+ T cell activation. Immunity 27: 625-634
    • (2007) Immunity , vol.27 , pp. 625-634
    • Celli, S.1    Lemaître, F.2    Bousso, P.3
  • 8
    • 79956116032 scopus 로고    scopus 로고
    • RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation
    • Codarri L, Gyülvészi G, Tosevski V, Hesske L, Fontana A, Magnenat L, Suter T, Becher B, (2011) RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation. Nat Immunol 12: 560-567
    • (2011) Nat Immunol , vol.12 , pp. 560-567
    • Codarri, L.1    Gyülvészi, G.2    Tosevski, V.3    Hesske, L.4    Fontana, A.5    Magnenat, L.6    Suter, T.7    Becher, B.8
  • 10
    • 0036081355 scopus 로고    scopus 로고
    • Gene Expression Omnibus: NCBI gene expression and hybridization array data repository
    • Edgar R, Domrachev M, Lash AE, (2002) Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res 30: 207-210
    • (2002) Nucleic Acids Res , vol.30 , pp. 207-210
    • Edgar, R.1    Domrachev, M.2    Lash, A.E.3
  • 14
    • 0035874640 scopus 로고    scopus 로고
    • CXCL10 (IFN-gamma-inducible protein-10) control of encephalitogenic CD4+ T cell accumulation in the central nervous system during experimental autoimmune encephalomyelitis
    • Fife BT, Kennedy KJ, Paniagua MC, Lukacs NW, Kunkel SL, Luster AD, Karpus WJ, (2001) CXCL10 (IFN-gamma-inducible protein-10) control of encephalitogenic CD4+ T cell accumulation in the central nervous system during experimental autoimmune encephalomyelitis. J Immunol 166: 7617-7624
    • (2001) J Immunol , vol.166 , pp. 7617-7624
    • Fife, B.T.1    Kennedy, K.J.2    Paniagua, M.C.3    Lukacs, N.W.4    Kunkel, S.L.5    Luster, A.D.6    Karpus, W.J.7
  • 15
    • 0035865406 scopus 로고    scopus 로고
    • Brain dendritic cells and macrophages/microglia in central nervous system inflammation
    • Fischer HG, Reichmann G, (2001) Brain dendritic cells and macrophages/microglia in central nervous system inflammation. J Immunol 166: 2717-2726
    • (2001) J Immunol , vol.166 , pp. 2717-2726
    • Fischer, H.G.1    Reichmann, G.2
  • 16
    • 37549061420 scopus 로고    scopus 로고
    • New angles on neuronal dendrites in vivo
    • Göbel W, Helmchen F, (2007) New angles on neuronal dendrites in vivo. J Neurophysiol 98: 3770-3779
    • (2007) J Neurophysiol , vol.98 , pp. 3770-3779
    • Göbel, W.1    Helmchen, F.2
  • 18
    • 33747623280 scopus 로고    scopus 로고
    • Interleukin 18-independent engagement of interleukin 18 receptor-alpha is required for autoimmune inflammation
    • Gutcher I, Urich E, Wolter K, Prinz M, Becher B, (2006) Interleukin 18-independent engagement of interleukin 18 receptor-alpha is required for autoimmune inflammation. Nat Immunol 7: 946-953
    • (2006) Nat Immunol , vol.7 , pp. 946-953
    • Gutcher, I.1    Urich, E.2    Wolter, K.3    Prinz, M.4    Becher, B.5
  • 19
    • 54849131500 scopus 로고    scopus 로고
    • Therapeutic targeting of chemokine signaling in Multiple Sclerosis
    • Hamann I, Zipp F, Infante-Duarte C, (2008) Therapeutic targeting of chemokine signaling in Multiple Sclerosis. J Neurol Sci 274: 31-38
    • (2008) J Neurol Sci , vol.274 , pp. 31-38
    • Hamann, I.1    Zipp, F.2    Infante-Duarte, C.3
  • 24
    • 33846558558 scopus 로고    scopus 로고
    • Kinetics and organ distribution of IL-17-producing CD4 cells in proteolipid protein 139-151 peptide-induced experimental autoimmune encephalomyelitis of SJL mice
    • Hofstetter HH, Toyka KV, Tary-Lehmann M, Lehmann PV, (2007) Kinetics and organ distribution of IL-17-producing CD4 cells in proteolipid protein 139-151 peptide-induced experimental autoimmune encephalomyelitis of SJL mice. J Immunol 178: 1372-1378
    • (2007) J Immunol , vol.178 , pp. 1372-1378
    • Hofstetter, H.H.1    Toyka, K.V.2    Tary-Lehmann, M.3    Lehmann, P.V.4
  • 28
    • 84867191763 scopus 로고    scopus 로고
    • Conditional DC depletion does not affect priming of encephalitogenic Th cells in EAE
    • Isaksson M, Lundgren BA, Ahlgren KM, Kämpe O, Lobell A, (2012) Conditional DC depletion does not affect priming of encephalitogenic Th cells in EAE. Eur J Immunol 42: 2555-2563
    • (2012) Eur J Immunol , vol.42 , pp. 2555-2563
    • Isaksson, M.1    Lundgren, B.A.2    Ahlgren, K.M.3    Kämpe, O.4    Lobell, A.5
  • 29
    • 33748588423 scopus 로고    scopus 로고
    • The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells
    • Ivanov II, McKenzie BS, Zhou L, Tadokoro CE, Lepelley A, Lafaille JJ, Cua DJ, Littman DR, (2006) The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell 126: 1121-1133
    • (2006) Cell , vol.126 , pp. 1121-1133
    • Ivanov, I.I.1    McKenzie, B.S.2    Zhou, L.3    Tadokoro, C.E.4    Lepelley, A.5    Lafaille, J.J.6    Cua, D.J.7    Littman, D.R.8
  • 31
    • 0034028817 scopus 로고    scopus 로고
    • Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion
    • Jung S, Aliberti J, Graemmel P, Sunshine MJ, Kreutzberg GW, Sher A, Littman DR, (2000) Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion. Mol Cell Biol 20: 4106-4114
    • (2000) Mol Cell Biol , vol.20 , pp. 4106-4114
    • Jung, S.1    Aliberti, J.2    Graemmel, P.3    Sunshine, M.J.4    Kreutzberg, G.W.5    Sher, A.6    Littman, D.R.7
  • 33
    • 33751562439 scopus 로고    scopus 로고
    • Dendritic cells amplify T cell-mediated immune responses in the central nervous system
    • Karman J, Chu HH, Co DO, Seroogy CM, Sandor M, Fabry Z, (2006) Dendritic cells amplify T cell-mediated immune responses in the central nervous system. J Immunol 177: 7750-7760
    • (2006) J Immunol , vol.177 , pp. 7750-7760
    • Karman, J.1    Chu, H.H.2    Co, D.O.3    Seroogy, C.M.4    Sandor, M.5    Fabry, Z.6
  • 34
    • 18644382218 scopus 로고    scopus 로고
    • Differential requirements for the chemokine receptor CCR7 in T cell activation during Listeria monocytogenes infection
    • Kursar M, Höpken UE, Koch M, Köhler A, Lipp M, Kaufmann SHE, Mittrücker H-W, (2005) Differential requirements for the chemokine receptor CCR7 in T cell activation during Listeria monocytogenes infection. J Exp Med 201: 1447-1457
    • (2005) J Exp Med , vol.201 , pp. 1447-1457
    • Kursar, M.1    Höpken, U.E.2    Koch, M.3    Köhler, A.4    Lipp, M.5    Kaufmann, S.H.E.6    Mittrücker, H.-W.7
  • 36
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method
    • Livak KJ, Schmittgen TD, (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method. Methods 25: 402-408
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 37
    • 0025259714 scopus 로고
    • Granulocyte-macrophage colony-stimulating factor promotes differentiation and survival of human peripheral blood dendritic cells in vitro
    • Markowicz S, Engleman EG, (1990) Granulocyte-macrophage colony-stimulating factor promotes differentiation and survival of human peripheral blood dendritic cells in vitro. J Clin Invest 85: 955-961
    • (1990) J Clin Invest , vol.85 , pp. 955-961
    • Markowicz, S.1    Engleman, E.G.2
  • 38
    • 16244417773 scopus 로고    scopus 로고
    • Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis
    • McMahon EJ, Bailey SL, Castenada CV, Waldner H, Miller SD, (2005) Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis. Nat Med 11: 335-339
    • (2005) Nat Med , vol.11 , pp. 335-339
    • McMahon, E.J.1    Bailey, S.L.2    Castenada, C.V.3    Waldner, H.4    Miller, S.D.5
  • 39
    • 0035283409 scopus 로고    scopus 로고
    • Chemokine receptor expression on T cells in blood and cerebrospinal fluid at relapse and remission of multiple sclerosis: Imbalance of Th1/Th2-associated chemokine signaling
    • Misu T, Onodera H, Fujihara K, Matsushima K, Yoshie O, Okita N, Takase S, Itoyama Y, (2001) Chemokine receptor expression on T cells in blood and cerebrospinal fluid at relapse and remission of multiple sclerosis: imbalance of Th1/Th2-associated chemokine signaling. J Neuroimmunol 114: 207-212
    • (2001) J Neuroimmunol , vol.114 , pp. 207-212
    • Misu, T.1    Onodera, H.2    Fujihara, K.3    Matsushima, K.4    Yoshie, O.5    Okita, N.6    Takase, S.7    Itoyama, Y.8
  • 41
    • 33846018916 scopus 로고    scopus 로고
    • GM-CSF production by autoreactive T cells is required for the activation of microglial cells and the onset of experimental autoimmune encephalomyelitis
    • Ponomarev ED, Shriver LP, Maresz K, Pedras-Vasconcelos J, Verthelyi D, Dittel BN, (2007) GM-CSF production by autoreactive T cells is required for the activation of microglial cells and the onset of experimental autoimmune encephalomyelitis. J Immunol 178: 39-48
    • (2007) J Immunol , vol.178 , pp. 39-48
    • Ponomarev, E.D.1    Shriver, L.P.2    Maresz, K.3    Pedras-Vasconcelos, J.4    Verthelyi, D.5    Dittel, B.N.6
  • 42
    • 15444366815 scopus 로고    scopus 로고
    • Priming of CTLs by lymphocytic choriomeningitis virus depends on dendritic cells
    • Probst HC, van den Broek M, (2005) Priming of CTLs by lymphocytic choriomeningitis virus depends on dendritic cells. J Immunol 174: 3920-3924
    • (2005) J Immunol , vol.174 , pp. 3920-3924
    • Probst, H.C.1    Van Den Broek, M.2
  • 45
    • 0037086967 scopus 로고    scopus 로고
    • IP-10 and MCP-1 levels in CSF and serum from multiple sclerosis patients with different clinical subtypes of the disease
    • Scarpini E, Galimberti D, Baron P, Clerici R, Ronzoni M, Conti G, Scarlato G, (2002) IP-10 and MCP-1 levels in CSF and serum from multiple sclerosis patients with different clinical subtypes of the disease. J Neurol Sci 195: 41-46
    • (2002) J Neurol Sci , vol.195 , pp. 41-46
    • Scarpini, E.1    Galimberti, D.2    Baron, P.3    Clerici, R.4    Ronzoni, M.5    Conti, G.6    Scarlato, G.7
  • 46
    • 84889687682 scopus 로고    scopus 로고
    • Organization of the mouse and human DC network
    • Schlitzer A, Ginhoux F, (2014) Organization of the mouse and human DC network. Curr Opin Immunol 26: 90-99
    • (2014) Curr Opin Immunol , vol.26 , pp. 90-99
    • Schlitzer, A.1    Ginhoux, F.2
  • 47
    • 35648943680 scopus 로고    scopus 로고
    • New insights into adaptive immunity in chronic neuroinflammation
    • Siffrin V, Brandt AU, Herz J, Zipp F, (2007) New insights into adaptive immunity in chronic neuroinflammation. Adv Immunol 96: 1-40
    • (2007) Adv Immunol , vol.96 , pp. 1-40
    • Siffrin, V.1    Brandt, A.U.2    Herz, J.3    Zipp, F.4
  • 50
    • 0034055609 scopus 로고    scopus 로고
    • Expression of the interferon-gamma-inducible chemokines IP-10 and Mig and their receptor, CXCR3, in multiple sclerosis lesions
    • Simpson JE, Newcombe J, Cuzner ML, Woodroofe MN, (2000) Expression of the interferon-gamma-inducible chemokines IP-10 and Mig and their receptor, CXCR3, in multiple sclerosis lesions. Neuropathol Appl Neurobiol 26: 133-142
    • (2000) Neuropathol Appl Neurobiol , vol.26 , pp. 133-142
    • Simpson, J.E.1    Newcombe, J.2    Cuzner, M.L.3    Woodroofe, M.N.4
  • 52
    • 74049134371 scopus 로고    scopus 로고
    • Mixed results with modulation of TH-17 cells in human autoimmune diseases
    • Steinman L, (2010) Mixed results with modulation of TH-17 cells in human autoimmune diseases. Nat Immunol 11: 41-44
    • (2010) Nat Immunol , vol.11 , pp. 41-44
    • Steinman, L.1
  • 53
    • 40449089827 scopus 로고    scopus 로고
    • Differential regulation of central nervous system autoimmunity by T(H)1 and T(H)17 cells
    • Stromnes IM, Cerretti LM, Liggitt D, Harris RA, Goverman JM, (2008) Differential regulation of central nervous system autoimmunity by T(H)1 and T(H)17 cells. Nat Med 14: 337-342
    • (2008) Nat Med , vol.14 , pp. 337-342
    • Stromnes, I.M.1    Cerretti, L.M.2    Liggitt, D.3    Harris, R.A.4    Goverman, J.M.5
  • 55
    • 0038240921 scopus 로고    scopus 로고
    • Ectopic germinal center formation in rheumatoid synovitis
    • Weyand CM, Goronzy JJ, (2003) Ectopic germinal center formation in rheumatoid synovitis. Ann N Y Acad Sci 987: 140-149
    • (2003) Ann N y Acad Sci , vol.987 , pp. 140-149
    • Weyand, C.M.1    Goronzy, J.J.2
  • 58
    • 27744523653 scopus 로고    scopus 로고
    • CD11chigh dendritic cell ablation impairs lymphopenia-driven proliferation of naive and memory CD8+ T cells
    • Zaft T, Sapoznikov A, Krauthgamer R, Littman DR, Jung S, (2005) CD11chigh dendritic cell ablation impairs lymphopenia-driven proliferation of naive and memory CD8+ T cells. J Immunol 175: 6428-6435
    • (2005) J Immunol , vol.175 , pp. 6428-6435
    • Zaft, T.1    Sapoznikov, A.2    Krauthgamer, R.3    Littman, D.R.4    Jung, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.