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Volumn , Issue , 2013, Pages 975-988

Drug-drug interaction: Enzyme induction

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EID: 84955335675     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-3-642-25240-2_43     Document Type: Chapter
Times cited : (1)

References (35)
  • 1
    • 0031714527 scopus 로고    scopus 로고
    • The relationship among microsomal enzyme induction, liver weight and histological change in rat toxicology studies
    • Amacher DE, Schomaker SJ, Burkhardt JE (1998) The relationship among microsomal enzyme induction, liver weight and histological change in rat toxicology studies. Food Chem Toxicol 36:831-839
    • (1998) Food Chem Toxicol , vol.36 , pp. 831-839
    • Amacher, D.E.1    Schomaker, S.J.2    Burkhardt, J.E.3
  • 2
    • 0034968708 scopus 로고    scopus 로고
    • The relationship among microsomal enzyme induction, liver weight and histological change in beagle dog toxicology studies
    • Amacher DE, Schomaker SJ, Burkhardt JE (2001) The relationship among microsomal enzyme induction, liver weight and histological change in beagle dog toxicology studies. Food Chem Toxicol 39:817-825
    • (2001) Food Chem Toxicol , vol.39 , pp. 817-825
    • Amacher, D.E.1    Schomaker, S.J.2    Burkhardt, J.E.3
  • 3
    • 77951713752 scopus 로고    scopus 로고
    • Pain management in the cirrhotic patient: The clinical challenge
    • Chandok N, Watt KDS (2010) Pain management in the cirrhotic patient: the clinical challenge. Mayo Clin Proc 85:451-458
    • (2010) Mayo Clin Proc , vol.85 , pp. 451-458
    • Chandok, N.1    Watt, K.2
  • 4
    • 67649404709 scopus 로고    scopus 로고
    • In vitro and in vivo induction of cytochrome p450: A survey of the current practises and recommendations: A pharmaceutical research and manufacturers of america perspective
    • Chu V, Einolf HJ, Evers R et al (2009) In vitro and in vivo induction of cytochrome P450: a survey of the current practises and recommendations: a pharmaceutical research and manufacturers of America perspective. Drug Metab Dispos 37:1339-1354
    • (2009) Drug Metab Dispos , vol.37 , pp. 1339-1354
    • Chu, V.1    Einolf, H.J.2    Evers, R.3
  • 5
    • 22844431873 scopus 로고    scopus 로고
    • Evaluation of mechanisms inducing thyroid toxicity and the ability of the enhanced oecd test guideline 407 to detect these changes
    • Cunha GC, van Ravenzwaay B (2005) Evaluation of mechanisms inducing thyroid toxicity and the ability of the enhanced OECD test guideline 407 to detect these changes. Arch Toxicol 79:390-405
    • (2005) Arch Toxicol , vol.79 , pp. 390-405
    • Cunha, G.C.1    Van Ravenzwaay, B.2
  • 6
    • 0035146956 scopus 로고    scopus 로고
    • Effects of organic solvents on the activities of cytochrome p450 isoforms, udp-dependent glucuronyl transferase, and phenol sulfotransferase in human hepatocytes
    • Easterbrook J, Lu C, Sakai Y et al (2001) Effects of organic solvents on the activities of cytochrome P450 isoforms, UDP-dependent glucuronyl transferase, and phenol sulfotransferase in human hepatocytes. Drug Metab Dispos 29:141-144
    • (2001) Drug Metab Dispos , vol.29 , pp. 141-144
    • Easterbrook, J.1    Lu, C.2    Sakai, Y.3
  • 7
    • 84955348527 scopus 로고    scopus 로고
    • Guidance for industry: Drug interaction studies -study design, data analysis, implications for dosing, and labeling recommendations. Draft guidance, rockville foisy mm, yakiwchuk em, hughes ca (2008) induction effects if ritonavir: Implications for drug interactions
    • FDA (2012) Guidance for industry: drug interaction studies -study design, data analysis, implications for dosing, and labeling recommendations. Draft guidance, Rockville Foisy MM, Yakiwchuk EM, Hughes CA (2008) Induction effects if ritonavir: implications for drug interactions. Ann Pharmacother 42:1048-1059
    • (2012) Ann Pharmacother , vol.42 , pp. 1048-1059
  • 8
    • 0029786432 scopus 로고    scopus 로고
    • Differential induction of prehepatic and hepatic metabolism of verapamil by rifampicin
    • Fromm MF, Busse D, Kroemer HK et al (1996) Differential induction of prehepatic and hepatic metabolism of verapamil by rifampicin. Hepatology 24:796-801
    • (1996) Hepatology , vol.24 , pp. 796-801
    • Fromm, M.F.1    Busse, D.2    Kroemer, H.K.3
  • 9
    • 0036842968 scopus 로고    scopus 로고
    • In vivo and in vitro induction of cytochrome p450 enzymes in beagle dogs
    • Graham RA, Downey A, Mudra D et al (2002) In vivo and in vitro induction of cytochrome P450 enzymes in beagle dogs. Drug Metab Dispos 30:1206-1213
    • (2002) Drug Metab Dispos , vol.30 , pp. 1206-1213
    • Graham, R.A.1    Downey, A.2    Mudra, D.3
  • 10
    • 34247505094 scopus 로고    scopus 로고
    • Induction of drug metabolizing enzymes: A survey of in vitro methodologies and interpretations used in the pharmaceutical industry - do they comply with fda recommendations?
    • Hewitt NJ, de Kanter R, LeClyse E (2007a) Induction of drug metabolizing enzymes: a survey of in vitro methodologies and interpretations used in the pharmaceutical industry - do they comply with FDA recommendations? Chem Biol Interact 168:51-65
    • (2007) Chem Biol Interact , vol.168 , pp. 51-65
    • Hewitt, N.J.1    De Kanter, R.2    Le Clyse, E.3
  • 11
    • 33847018050 scopus 로고    scopus 로고
    • Primary hepatocytes: Current understanding of the regulation of metabolic enzymes and transporter proteins, and pharmaceutical practice for the use of hepatocytes in metabolism, enzyme induction, transporter, clearance, and hepatotoxicity studies
    • Hewitt NJ, Gomez Lechon MJ, Houstan JB et al (2007b) Primary hepatocytes: current understanding of the regulation of metabolic enzymes and transporter proteins, and pharmaceutical practice for the use of hepatocytes in metabolism, enzyme induction, transporter, clearance, and hepatotoxicity studies. Drug Metab Dispos 39:159-234
    • (2007) Drug Metab Dispos , vol.39 , pp. 159-234
    • Hewitt, N.J.1    Gomez Lechon, M.J.2    Houstan, J.B.3
  • 12
    • 35648976075 scopus 로고    scopus 로고
    • Induction of hepatic cytochrome p450 enzymes: Methods, mechanisms, recommendations, and in vitro-in vivo correlations
    • Hewitt NJ, LeClyse EL, Fergusson SS (2007c) Induction of hepatic cytochrome P450 enzymes: methods, mechanisms, recommendations, and in vitro-in vivo correlations. Xenobiotica 37:1196-1224
    • (2007) Xenobiotica , vol.37 , pp. 1196-1224
    • Hewitt, N.J.1    Le Clyse, E.L.2    Fergusson, S.S.3
  • 13
    • 0034655747 scopus 로고    scopus 로고
    • Regulation of cytochrome p450 (Cyp) genes by nuclear receptors
    • Honkakoski P, Negishi M (2000) Regulation of cytochrome P450 (CYP) genes by nuclear receptors. Biochem J 347:321-337
    • (2000) Biochem J , vol.347 , pp. 321-337
    • Honkakoski, P.1    Negishi, M.2
  • 14
    • 33846244208 scopus 로고    scopus 로고
    • Evaluation of the effects of hydrophilic organic solvents on cyp3a-mediated drug-drug interaction in vitro
    • Iwase M, Kurata N, Ehana R et al (2006) Evaluation of the effects of hydrophilic organic solvents on CYP3A-mediated drug-drug interaction in vitro. Hum Exp Toxicol 25:715-721
    • (2006) Hum Exp Toxicol , vol.25 , pp. 715-721
    • Iwase, M.1    Kurata, N.2    Ehana, R.3
  • 15
    • 17744375160 scopus 로고    scopus 로고
    • The pregnane x receptor: A promiscuous xenobiotic receptor that has diverged during evolution
    • Jones SA, Moore LB, Shenk JL et al (2000) The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution. Mol Endocrinol 14:27-39
    • (2000) Mol Endocrinol , vol.14 , pp. 27-39
    • Jones, S.A.1    Moore, L.B.2    Shenk, J.L.3
  • 16
    • 84955370511 scopus 로고    scopus 로고
    • Prediction of clinical cyp3a4 induction using cryopreserved human hepatocytes. Xenobiotica 40:791-799 kewley rj, whitelaw ml, chapman-smith a (2004) the mammalian basic helix-loop-helix/pas family of transcriptional regulators
    • Kaneko A, Kato M, Endo C et al (2010) Prediction of clinical CYP3A4 induction using cryopreserved human hepatocytes. Xenobiotica 40:791-799 Kewley RJ, Whitelaw ML, Chapman-Smith A (2004) The mammalian basic helix-loop-helix/PAS family of transcriptional regulators. Int J Biochem Cell Biol 36:189-204
    • (2010) Int J Biochem Cell Biol , vol.36 , pp. 189-204
    • Kaneko, A.1    Kato, M.2    Endo, C.3
  • 17
    • 84955418730 scopus 로고    scopus 로고
    • Sanofi-Aventis Deutschland GmbH, Frankfurt, Germany
    • Koose T, Biinning P (2010) Drug Disposition. Sanofi-Aventis Deutschland GmbH, Frankfurt, Germany
    • (2010) Drug Disposition
    • Koose, T.1    Biinning, P.2
  • 18
    • 0031727339 scopus 로고    scopus 로고
    • Effects of rifabutin and rifampicin on the pharmacokinetics of ethinylestradiol and norethindrone
    • LeBel M, Masson E, Guilbert E et al (1998) Effects of rifabutin and rifampicin on the pharmacokinetics of ethinylestradiol and norethindrone. J Clin Pharmacol 38:1042-1050
    • (1998) J Clin Pharmacol , vol.38 , pp. 1042-1050
    • Le Bel, M.1    Masson, E.2    Guilbert, E.3
  • 19
    • 0035897713 scopus 로고    scopus 로고
    • Pregnane x receptor: Molecular basis for species differences in cyp3a induction by xenobiotics
    • LeClyse EL (2001) Pregnane X receptor: molecular basis for species differences in CYP3A induction by xenobiotics. Chem Biol Interact 134:283-289
    • (2001) Chem Biol Interact , vol.134 , pp. 283-289
    • Le Clyse, E.L.1
  • 21
    • 33751579139 scopus 로고    scopus 로고
    • Drug-induced changes in p450 enzyme expression at the gene expression level: A new dimension to the analysis of drug-drug interactions
    • Lee MD, Ayanoglu E, Gong L (2006) Drug-induced changes in P450 enzyme expression at the gene expression level: a new dimension to the analysis of drug-drug interactions. Xenobiotica 36:1013-1080
    • (2006) Xenobiotica , vol.36 , pp. 1013-1080
    • Lee, M.D.1    Ayanoglu, E.2    Gong, L.3
  • 22
    • 0032169485 scopus 로고    scopus 로고
    • The human orphan nuclear receptor pxr is activated by compounds that regulate cyp3a4 gene expression and cause drug interactions
    • Lehmann JM, McKee DD, Watson MA et al (1998) The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions. J Clin Invest 102:1016-1023
    • (1998) J Clin Invest , vol.102 , pp. 1016-1023
    • Lehmann, J.M.1    Mc Kee, D.D.2    Watson, M.A.3
  • 23
    • 0032727340 scopus 로고    scopus 로고
    • Effects of cytochrome p450 inducers on 17a-ethinylestradiol (Ee2) conjugation by primary human hepatocytes
    • Li AP, Hartman NR, Lu C et al (1999) Effects of cytochrome P450 inducers on 17a-ethinylestradiol (EE2) conjugation by primary human hepatocytes. Br J Clin Pharmacol 48:733-742
    • (1999) Br J Clin Pharmacol , vol.48 , pp. 733-742
    • Li, A.P.1    Hartman, N.R.2    Lu, C.3
  • 24
    • 0035897710 scopus 로고    scopus 로고
    • Species comparison in p450 induction: Effects of dexamethasone, omeprazole and rifampin on p450 isoforms 1a and 3a in primary hepatocytes from man, sprague-dawley rat, minipig and beagle dog
    • Lu C, Li AP (2001) Species comparison in P450 induction: effects of dexamethasone, omeprazole and rifampin on P450 isoforms 1A and 3A in primary hepatocytes from man, Sprague-Dawley rat, minipig and beagle dog. Chem Biol Interact 134:271-281
    • (2001) Chem Biol Interact , vol.134 , pp. 271-281
    • Lu, C.1    Li, A.P.2
  • 25
    • 0037379409 scopus 로고    scopus 로고
    • Effects of prototypical microsomal enzyme inducers on cytochrome p450 expression in cultures human hepatocytes
    • Madan A, Graham RA, Carroll KM et al (2003) Effects of prototypical microsomal enzyme inducers on cytochrome P450 expression in cultures human hepatocytes. Drug Metab Dispos 31:421-431
    • (2003) Drug Metab Dispos , vol.31 , pp. 421-431
    • Madan, A.1    Graham, R.A.2    Carroll, K.M.3
  • 27
    • 66649089506 scopus 로고    scopus 로고
    • Evaluation of multiple in vitro systems for assessment of cyp3a4 induction in drug discovery: Human hepatocytes, pregnane x receptor reporter gene, and fa2n-4 and heparg cells
    • McGinnity DF, Zhang G, Kenny JR et al (2009) Evaluation of multiple in vitro systems for assessment of CYP3A4 induction in drug discovery: human hepatocytes, pregnane X receptor reporter gene, and Fa2N-4 and HepaRG cells. Drug Metab Dispos 37:1259-1268
    • (2009) Drug Metab Dispos , vol.37 , pp. 1259-1268
    • Mc Ginnity, D.F.1    Zhang, G.2    Kenny, J.R.3
  • 28
    • 79851505734 scopus 로고    scopus 로고
    • Current in vitro high throughput screening approaches to assess nuclear receptor activation
    • Raucy JL, Lasker JM (2010) Current in vitro high throughput screening approaches to assess nuclear receptor activation. Curr Drug Metab 11:806-814
    • (2010) Curr Drug Metab , vol.11 , pp. 806-814
    • Raucy, J.L.1    Lasker, J.M.2
  • 29
    • 0024401849 scopus 로고
    • Acetaminophen activation by human liver cytochromes p450iie1 and p450ia2
    • Raucy JL, Lasker JM, Lieber CS et al (1989) Acetaminophen activation by human liver cytochromes P450IIE1 and P450IA2. Arch Biochem Biophys 271:270-283
    • (1989) Arch Biochem Biophys , vol.271 , pp. 270-283
    • Raucy, J.L.1    Lasker, J.M.2    Lieber, C.S.3
  • 30
    • 10744233944 scopus 로고    scopus 로고
    • Determination of cytochrome p450 1a2 and cytochrome p450 3a4 induction in cryopreserved human hepatocytes
    • Roymans D, Van Looveren C, Leone A et al (2005) Determination of cytochrome P450 1A2 and cytochrome P450 3A4 induction in cryopreserved human hepatocytes. Biochem Pharmacol 67:427-437
    • (2005) Biochem Pharmacol , vol.67 , pp. 427-437
    • Roymans, D.1    Van Looveren, C.2    Leone, A.3
  • 31
    • 84955360060 scopus 로고    scopus 로고
    • Proprietary information. Search-LC GmbH, Heidelberg, Germany
    • Search-LC GmbH (2010) Proprietary information. Search-LC GmbH, Heidelberg, Germany
  • 32
    • 54349113314 scopus 로고    scopus 로고
    • Modeling, prediction, and in vitro in vivo correlation of cyp3a4 induction
    • Shou M, Hayashi M, Pan Y et al (2008) Modeling, prediction, and in vitro in vivo correlation of CYP3A4 induction. Drug Metab Dispos 36:2355-2370
    • (2008) Drug Metab Dispos , vol.36 , pp. 2355-2370
    • Shou, M.1    Hayashi, M.2    Pan, Y.3
  • 33
    • 0035038008 scopus 로고    scopus 로고
    • Phenobarbital response elements of cytochrome p450 genes and nuclear receptors
    • Sueyoshi T, Negishi M (2001) Phenobarbital response elements of cytochrome P450 genes and nuclear receptors. Annu Rev Pharmacol Toxicol 41:123-143
    • (2001) Annu Rev Pharmacol Toxicol , vol.41 , pp. 123-143
    • Sueyoshi, T.1    Negishi, M.2
  • 34
    • 6944229545 scopus 로고    scopus 로고
    • The involvement of cyp3a4 and cyp2c9 in the metabolism of 17a-ethinylestradiol
    • Wang B, Sanchez RI, Franklin RB et al (2004) The involvement of CYP3A4 and CYP2C9 in the metabolism of 17a-ethinylestradiol. Drug Metab Dispos 32:1209-1212
    • (2004) Drug Metab Dispos , vol.32 , pp. 1209-1212
    • Wang, B.1    Sanchez, R.I.2    Franklin, R.B.3
  • 35
    • 0033199499 scopus 로고    scopus 로고
    • P450 gene induction by structurally diverse xenochemicals: Central role of nuclear receptors car, pxr, and ppar
    • Waxman DJ (1999) P450 gene induction by structurally diverse xenochemicals: central role of nuclear receptors CAR, PXR, and PPAR. Arch Biochem Biophys 369:11-23
    • (1999) Arch Biochem Biophys , vol.369 , pp. 11-23
    • Waxman, D.J.1


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