Organisation and dynamics of antigen receptors: Implications for lymphocyte signalling

Current Opinion in Immunology

Volumn 22, Issue 3, 2010, Pages 299-307

  Treanor, Bebhinn ^a   Batista, Facundo D ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; B LYMPHOCYTE RECEPTOR; EZRIN; GALECTIN; GREEN FLUORESCENT PROTEIN; LYMPHOCYTE ANTIGEN RECEPTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MOESIN; RADIXIN; TRANSMEMBRANE CONDUCTANCE REGULATOR; MEMBRANE PROTEIN;

AMINO TERMINAL SEQUENCE; CARBOXY TERMINAL SEQUENCE; CELL COMPARTMENTALIZATION; CELL MEMBRANE; CYTOSKELETON; DIFFUSION; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMAN; LIPID ANALYSIS; MOLECULAR DYNAMICS; MOLECULAR MODEL; NONHUMAN; PROTEIN ANALYSIS; PROTEIN DETERMINATION; PROTEIN DOMAIN; RECEPTOR BINDING; REVIEW; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; T LYMPHOCYTE; TRANSMISSION ELECTRON MICROSCOPY; BIOLOGICAL MODEL; IMMUNOLOGY; LYMPHOCYTE; LYMPHOCYTE ACTIVATION; METABOLISM;

CELL MEMBRANE; HUMANS; LYMPHOCYTE ACTIVATION; LYMPHOCYTES; MEMBRANE PROTEINS; MODELS, BIOLOGICAL; RECEPTORS, ANTIGEN; SIGNAL TRANSDUCTION;

EID: 77953536657     PISSN: 09527915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.coi.2010.03.009     Document Type: Review

References (59)

1. Monroe J.G. Ligand-independent tonic signaling in B-cell receptor function. Curr Opin Immunol 2004, 16:288-295.
2. Rajewsky K. Clonal selection and learning in the antibody system. Nature 1996, 381:751-758.
3. Lam K.P., Kuhn R., Rajewsky K. In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death. Cell 1997, 90:1073-1083.
4. Singer S.J., Nicolson G.L. The fluid mosaic model of the structure of cell membranes. Science 1972, 175:720-731.
5. Edidin M., Zagyansky Y., Lardner T.J. Measurement of membrane protein lateral diffusion in single cells. Science 1976, 191:466-468.
6. Fowler V., Branton D. Lateral mobility of human erythrocyte integral membrane proteins. Nature 1977, 268:23-26.
7. Jacobson K., Wu E., Poste G. Measurement of the translational mobility of concanavalin A in glycerol-saline solutions and on the cell surface by fluorescence recovery after photobleaching. Biochim Biophys Acta 1976, 433:215-222.
8. Schindler M., Koppel D.E., Sheetz M.P. Modulation of membrane protein lateral mobility by polyphosphates and polyamines. Proc Natl Acad Sci U S A 1980, 77:1457-1461.
9. Schlessinger J., Axelrod D., Koppel D.E., Webb W.W., Elson E.L. Lateral transport of a lipid probe and labeled proteins on a cell membrane. Science 1977, 195:307-309.
10. Edidin M., Zuniga M.C., Sheetz M.P. Truncation mutants define and locate cytoplasmic barriers to lateral mobility of membrane glycoproteins. Proc Natl Acad Sci U S A 1994, 91:3378-3382.
11. Sheetz M.P., Schindler M., Koppel D.E. Lateral mobility of integral membrane proteins is increased in spherocytic erythrocytes. Nature 1980, 285:510-511.
12. Simson R., Sheets E.D., Jacobson K. Detection of temporary lateral confinement of membrane proteins using single-particle tracking analysis. Biophys J 1995, 69:989-993.
13. Kusumi A., Sako Y., Yamamoto M. Confined lateral diffusion of membrane receptors as studied by single particle tracking (nanovid microscopy). Effects of calcium-induced differentiation in cultured epithelial cells. Biophys J 1993, 65:2021-2040.
14. Fujiwara T., Ritchie K., Murakoshi H., Jacobson K., Kusumi A. Phospholipids undergo hop diffusion in compartmentalized cell membrane. J Cell Biol 2002, 157:1071-1081.
15. Tsuji A., Ohnishi S. Restriction of the lateral motion of band 3 in the erythrocyte membrane by the cytoskeletal network: dependence on spectrin association state. Biochemistry 1986, 25:6133-6139.
16. Wade W.F., Freed J.H., Edidin M. Translational diffusion of class II major histocompatibility complex molecules is constrained by their cytoplasmic domains. J Cell Biol 1989, 109:3325-3331.
17. Sako Y., Kusumi A. Compartmentalized structure of the plasma membrane for receptor movements as revealed by a nanometer-level motion analysis. J Cell Biol 1994, 125:1251-1264.
18. Charrier C., Ehrensperger M.V., Dahan M., Levi S., Triller A. Cytoskeleton regulation of glycine receptor number at synapses and diffusion in the plasma membrane. J Neurosci 2006, 26:8502-8511.
19. Lenne P.F., Wawrezinieck L., Conchonaud F., Wurtz O., Boned A., Guo X.J., Rigneault H., He H.T., Marguet D. Dynamic molecular confinement in the plasma membrane by microdomains and the cytoskeleton meshwork. EMBO J 2006, 25:3245-3256.
20. Kusumi A., Nakada C., Ritchie K., Murase K., Suzuki K., Murakoshi H., Kasai R.S., Kondo J., Fujiwara T. Paradigm shift of the plasma membrane concept from the two-dimensional continuum fluid to the partitioned fluid: high-speed single-molecule tracking of membrane molecules. Annu Rev Biophys Biomol Struct 2005, 34:351-378.
21. Morone N., Fujiwara T., Murase K., Kasai R.S., Ike H., Yuasa S., Usukura J., Kusumi A. Three-dimensional reconstruction of the membrane skeleton at the plasma membrane interface by electron tomography. J Cell Biol 2006, 174:851-862.
22. Andrews N.L., Lidke K.A., Pfeiffer J.R., Burns A.R., Wilson B.S., Oliver J.M., Lidke D.S. Actin restricts Fce{open}RI diffusion and facilitates antigen-induced receptor immobilization. Nat Cell Biol 2008, 10:955-963.
23. Treanor B., Depoil D., Gonzalez-Granja A., Barral P., Weber M., Dushek O., Bruckbauer A., Batista F.D. The membrane skeleton controls diffusion dynamics and signaling through the B cell receptor. Immunity 2010, 32:187-199.
24. Bretscher A., Edwards K., Fehon R.G. ERM proteins and merlin: integrators at the cell cortex. Nat Rev Mol Cell Biol 2002, 3:586-599.
25. Haggie P.M., Kim J.K., Lukacs G.L., Verkman A.S. Tracking of quantum dot-labeled CFTR shows near immobilization by C-terminal PDZ interactions. Mol Biol Cell 2006, 17:4937-4945.
26. Wheeler D., Sneddon W.B., Wang B., Friedman P.A., Romero G. NHERF-1 and the cytoskeleton regulate the traffic and membrane dynamics of G protein-coupled receptors. J Biol Chem 2007, 282:25076-25087.
27. Damjanovich S., Vereb G., Schaper A., Jenei A., Matko J., Starink J.P., Fox G.Q., Arndt-Jovin D.J., Jovin T.M. Structural hierarchy in the clustering of HLA class I molecules in the plasma membrane of human lymphoblastoid cells. Proc Natl Acad Sci U S A 1995, 92:1122-1126.
28. Lillemeier B.F., Pfeiffer J.R., Surviladze Z., Wilson B.S., Davis M.M. Plasma membrane-associated proteins are clustered into islands attached to the cytoskeleton. Proc Natl Acad Sci U S A 2006, 103:18992-18997.
29. Wilson B.S., Steinberg S.L., Liederman K., Pfeiffer J.R., Surviladze Z., Zhang J., Samelson L.E., Yang L.H., Kotula P.G., Oliver J.M. Markers for detergent-resistant lipid rafts occupy distinct and dynamic domains in native membranes. Mol Biol Cell 2004, 15:2580-2592.
30. Kim J.H., Cramer L., Mueller H., Wilson B., Vilen B.J. Independent trafficking of Ig-alpha/Ig-beta and mu-heavy chain is facilitated by dissociation of the B cell antigen receptor complex. J Immunol 2005, 175:147-154.
31. Simons K., Ikonen E. Functional rafts in cell membranes. Nature 1997, 387:569-572.
32. Cheng P.C., Dykstra M.L., Mitchell R.N., Pierce S.K. A role for lipid rafts in B cell antigen receptor signaling and antigen targeting. J Exp Med 1999, 190:1549-1560.
33. Sohn H.W., Tolar P., Jin T., Pierce S.K. Fluorescence resonance energy transfer in living cells reveals dynamic membrane changes in the initiation of B cell signaling. Proc Natl Acad Sci U S A 2006, 103:8143-8148.
34. Dykstra M., Cherukuri A., Sohn H.W., Tzeng S.J., Pierce S.K. Location is everything: lipid rafts and immune cell signaling. Annu Rev Immunol 2003, 21:457-481.
35. Dietrich C., Bagatolli L.A., Volovyk Z.N., Thompson N.L., Levi M., Jacobson K., Gratton E. Lipid rafts reconstituted in model membranes. Biophys J 2001, 80:1417-1428.
36. Xu C., Gagnon E., Call M.E., Schnell J.R., Schwieters C.D., Carman C.V., Chou J.J., Wucherpfennig K.W. Regulation of T cell receptor activation by dynamic membrane binding of the CD3e{open} cytoplasmic tyrosine-based motif. Cell 2008, 135:702-713.
37. Douglass A.D., Vale R.D. Single-molecule microscopy reveals plasma membrane microdomains created by protein-protein networks that exclude or trap signaling molecules in T cells. Cell 2005, 121:937-950.
38. Vrljic M., Nishimura S.Y., Brasselet S., Moerner W.E., McConnell H.M. Translational diffusion of individual class II MHC membrane proteins in cells. Biophys J 2002, 83:2681-2692.
39. Umemura Y.M., Vrljic M., Nishimura S.Y., Fujiwara T.K., Suzuki K.G., Kusumi A. Both MHC class II and its GPI-anchored form undergo hop diffusion as observed by single-molecule tracking. Biophys J 2008, 95:435-450.
40. Nishimura S.Y., Vrljic M., Klein L.O., McConnell H.M., Moerner W.E. Cholesterol depletion induces solid-like regions in the plasma membrane. Biophys J 2006, 90:927-938.
41. Vrljic M., Nishimura S.Y., Moerner W.E., McConnell H.M. Cholesterol depletion suppresses the translational diffusion of class II major histocompatibility complex proteins in the plasma membrane. Biophys J 2005, 88:334-347.
42. Eggeling C., Ringemann C., Medda R., Schwarzmann G., Sandhoff K., Polyakova S., Belov V.N., Hein B., von Middendorff C., Schonle A., et al. Direct observation of the nanoscale dynamics of membrane lipids in a living cell. Nature 2009, 457:1159-1162.
43. Brewer C.F., Miceli M.C., Baum L.G. Clusters, bundles, arrays and lattices: novel mechanisms for lectin-saccharide-mediated cellular interactions. Curr Opin Struct Biol 2002, 12:616-623.
44. Grigorian A., Torossian S., Demetriou M. T-cell growth, cell surface organization, and the galectin-glycoprotein lattice. Immunol Rev 2009, 230:232-246.
45. Lajoie P., Goetz J.G., Dennis J.W., Nabi I.R. Lattices, rafts, and scaffolds: domain regulation of receptor signaling at the plasma membrane. J Cell Biol 2009, 185:381-385.
46. Chen I.J., Chen H.L., Demetriou M. Lateral compartmentalization of T cell receptor versus CD45 by galectin-N-glycan binding and microfilaments coordinate basal and activation signaling. J Biol Chem 2007, 282:35361-35372.
47. Lajoie P., Partridge E.A., Guay G., Goetz J.G., Pawling J., Lagana A., Joshi B., Dennis J.W., Nabi I.R. Plasma membrane domain organization regulates EGFR signaling in tumor cells. J Cell Biol 2007, 179:341-356.
48. Hao S., August A. Actin depolymerization transduces the strength of B-cell receptor stimulation. Mol Biol Cell 2005, 16:2275-2284.
49. Weber M., Treanor B., Depoil D., Shinohara H., Harwood N.E., Hikida M., Kurosaki T., Batista F.D. Phospholipase C-gamma2 and Vav cooperate within signaling microclusters to propagate B cell spreading in response to membrane-bound antigen. J Exp Med 2008, 205:853-868.
50. Schamel W.W., Reth M. Stability of the B cell antigen receptor complex. Mol Immunol 2000, 37:253-259.
51. Reth M., Wienands J., Schamel W.W. An unsolved problem of the clonal selection theory and the model of an oligomeric B-cell antigen receptor. Immunol Rev 2000, 176:10-18.
52. Guo B., Kato R.M., Garcia-Lloret M., Wahl M.I., Rawlings D.J. Engagement of the human pre-B cell receptor generates a lipid raft-dependent calcium signaling complex. Immunity 2000, 13:243-253.
53. Monroe J.G. ITAM-mediated tonic signalling through pre-BCR and BCR complexes. Nat Rev Immunol 2006, 6:283-294.
54. Lillemeier B.F., Mortelmaier M.A., Forstner M.B., Huppa J.B., Groves J.T., Davis M.M. TCR and Lat are expressed on separate protein islands on T cell membranes and concatenate during activation. Nat Immunol 2010, 11:90-96.
55. Ganguly S., Pucadyil T.J., Chattopadhyay A. Actin cytoskeleton-dependent dynamics of the human serotonin1A receptor correlates with receptor signaling. Biophys J 2008, 95:451-463.
56. Gupta N., Wollscheid B., Watts J.D., Scheer B., Aebersold R., DeFranco A.L. Quantitative proteomic analysis of B cell lipid rafts reveals that ezrin regulates antigen receptor-mediated lipid raft dynamics. Nat Immunol 2006, 7:625-633.
57. Delon J., Kaibuchi K., Germain R.N. Exclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesin. Immunity 2001, 15:691-701.
58. Faure S., Salazar-Fontana L.I., Semichon M., Tybulewicz V.L., Bismuth G., Trautmann A., Germain R.N., Delon J. ERM proteins regulate cytoskeleton relaxation promoting T cell-APC conjugation. Nat Immunol 2004, 5:272-279.
59. Andrews N.L., Pfeiffer J.R., Martinez A.M., Haaland D.M., Davis R.W., Kawakami T., Oliver J.M., Wilson B.S., Lidke D.S. Small, mobile Fce{open}RI receptor aggregates are signaling competent. Immunity 2009, 31:469-479.