An immunoglobulin Cκ-reactive single chain antibody fusion protein induces tolerance through receptor editing in a normal polyclonal immune system

Journal of Experimental Medicine

Volumn 201, Issue 5, 2005, Pages 817-828

  Ait Azzouzene, Djemel ^a   Verkoczy, Laurent ^a   Peters, Jorieke ^a,b   Gavin, Amanda ^a   Skog, Patrick ^a   Vela, José Luis ^a   Nemazee, David ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CHIMERIC PROTEIN; HYBRID PROTEIN; IMMUNOGLOBULIN KAPPA CHAIN; POLYCLONAL ANTIBODY; SUPERANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; B LYMPHOCYTE; BONE MARROW; CHIMERA; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; IMMUNOLOGICAL TOLERANCE; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECIPIENT; TRANSGENE; TRANSGENIC MOUSE;

ANIMALS; AUTOANTIGENS; B-LYMPHOCYTES; BONE MARROW CELLS; BONE MARROW TRANSPLANTATION; CELL LINE, TUMOR; GENES, RAG-1; IMMUNE SYSTEM; IMMUNE TOLERANCE; IMMUNOGLOBULIN KAPPA-CHAINS; IMMUNOGLOBULIN LAMBDA-CHAINS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MUTATION; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RECOMBINANT FUSION PROTEINS;

EID: 15444371841     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20041854     Document Type: Article

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