Age modifies respiratory complex I and protein homeostasis in a muscle type-specific manner

Aging Cell

Volumn 15, Issue 1, 2016, Pages 89-99

  Kruse, Shane E ^a   Karunadharma, Pabalu P ^b,c   Basisty, Nathan ^b   Johnson, Richard ^b   Beyer, Richard P ^b   Maccoss, Michael J ^b   Rabinovitch, Peter S ^b   Marcinek, David J ^a,b,d  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

^d University of Washington   (United States)

Author keywords

Aging; Mitochondria; Mitochondrial dysfunction; Protein turnover; Proteome; Skeletal muscle

Indexed keywords

CATALASE; HYDROGEN PEROXIDE; MITOCHONDRIAL PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE);

AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EXTENSOR DIGITORUM LONGUS MUSCLE; FEMALE; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN HOMEOSTASIS; PROTEIN METABOLISM; PROTEOMICS; RESPIRATORY FUNCTION; SOLEUS MUSCLE; TISSUE SPECIFICITY; ANIMAL; C57BL MOUSE; FAST MUSCLE FIBER; HOMEOSTASIS; METABOLISM; PHYSIOLOGY; SLOW MUSCLE FIBER;

AGING; ANIMALS; ELECTRON TRANSPORT COMPLEX I; FEMALE; HOMEOSTASIS; MICE, INBRED C57BL; MITOCHONDRIA; MUSCLE FIBERS, FAST-TWITCH; MUSCLE FIBERS, SLOW-TWITCH; PROTEOMICS;

EID: 84955201688     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12412     Document Type: Article

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