-
1
-
-
0022350602
-
Yeast mRNA splicing in vitro
-
Lin R.J., Newman A.J., Cheng S.C., Abelson J. Yeast mRNA splicing in vitro. J Biol Chem 1985, 260:14780-14792.
-
(1985)
J Biol Chem
, vol.260
, pp. 14780-14792
-
-
Lin, R.J.1
Newman, A.J.2
Cheng, S.C.3
Abelson, J.4
-
2
-
-
0001468848
-
Splicing of precursors to mRNAs by the spliceosome
-
Cold Spring Harbor Laboratory Press, R.F. Gesteland, T.R. Cech, J.F. Atkins (Eds.)
-
Burge C.B., Tuschl T., Sharp P.A. Splicing of precursors to mRNAs by the spliceosome. The RNA World II 1999, 525-560. Cold Spring Harbor Laboratory Press. R.F. Gesteland, T.R. Cech, J.F. Atkins (Eds.).
-
(1999)
The RNA World II
, pp. 525-560
-
-
Burge, C.B.1
Tuschl, T.2
Sharp, P.A.3
-
3
-
-
0000996356
-
The growing world of small nuclear ribonucleoproteins
-
Cold Spring Harbor Laboratory Press, R.F. Gesteland, T.R. Cech, J.F. Atkins (Eds.)
-
Yu Y.-T., Scharl E.C., Smith C.M., Steitz J.A. The growing world of small nuclear ribonucleoproteins. The RNA World II 1999, 487-524. Cold Spring Harbor Laboratory Press. R.F. Gesteland, T.R. Cech, J.F. Atkins (Eds.).
-
(1999)
The RNA World II
, pp. 487-524
-
-
Yu, Y.-T.1
Scharl, E.C.2
Smith, C.M.3
Steitz, J.A.4
-
5
-
-
0028365538
-
Functional association of essential splicing factor(s) with PRP19 in a protein complex
-
Tarn W.Y., Hsu C.H., Huang K.T., Chen H.R., Kao H.Y., Lee K.R., Cheng S.C. Functional association of essential splicing factor(s) with PRP19 in a protein complex. EMBO J 1994, 13:2421-2431.
-
(1994)
EMBO J
, vol.13
, pp. 2421-2431
-
-
Tarn, W.Y.1
Hsu, C.H.2
Huang, K.T.3
Chen, H.R.4
Kao, H.Y.5
Lee, K.R.6
Cheng, S.C.7
-
6
-
-
0026486883
-
A novel base-pairing interaction between U2 and U6 snRNAs suggests a mechanism for catalytic activation of the spliceosome
-
Madhani H.D., Guthrie C. A novel base-pairing interaction between U2 and U6 snRNAs suggests a mechanism for catalytic activation of the spliceosome. Cell 1992, 71:803-817.
-
(1992)
Cell
, vol.71
, pp. 803-817
-
-
Madhani, H.D.1
Guthrie, C.2
-
7
-
-
84887624226
-
RNA catalyses nuclear pre-mRNA splicing
-
Fica S.M., Tuttle N., Novak T., Li N.S., Lu J., Koodathingal P., Dai Q., Staley J.P., Piccirilli J.A. RNA catalyses nuclear pre-mRNA splicing. Nature 2013, 503:229-234.
-
(2013)
Nature
, vol.503
, pp. 229-234
-
-
Fica, S.M.1
Tuttle, N.2
Novak, T.3
Li, N.S.4
Lu, J.5
Koodathingal, P.6
Dai, Q.7
Staley, J.P.8
Piccirilli, J.A.9
-
8
-
-
84901929739
-
Evidence for a group II intron-like catalytic triplex in the spliceosome
-
Fica S.M., Mefford M.A., Piccirilli J.A., Staley J.P. Evidence for a group II intron-like catalytic triplex in the spliceosome. Nat Struct Mol Biol 2014, 21:464-471.
-
(2014)
Nat Struct Mol Biol
, vol.21
, pp. 464-471
-
-
Fica, S.M.1
Mefford, M.A.2
Piccirilli, J.A.3
Staley, J.P.4
-
9
-
-
41749109563
-
Crystal structure of a self-spliced group II intron
-
Toor N., Keating K.S., Taylor S.D., Pyle A.M. Crystal structure of a self-spliced group II intron. Science 2008, 320:77-82.
-
(2008)
Science
, vol.320
, pp. 77-82
-
-
Toor, N.1
Keating, K.S.2
Taylor, S.D.3
Pyle, A.M.4
-
10
-
-
0026605043
-
U5 snRNA interacts with exon sequences at 5' and 3' splice sites
-
Newman A.J., Norman C. U5 snRNA interacts with exon sequences at 5' and 3' splice sites. Cell 1992, 68:743-754.
-
(1992)
Cell
, vol.68
, pp. 743-754
-
-
Newman, A.J.1
Norman, C.2
-
11
-
-
0027739853
-
The U5 and U6 small nuclear RNAs as active site components of the spliceosome
-
Sontheimer E.J., Steitz J.A. The U5 and U6 small nuclear RNAs as active site components of the spliceosome. Science 1993, 262:1989-1996.
-
(1993)
Science
, vol.262
, pp. 1989-1996
-
-
Sontheimer, E.J.1
Steitz, J.A.2
-
12
-
-
84874268195
-
Dissection of the factor requirements for spliceosome disassembly and the elucidation of its dissociation products using a purified splicing system
-
Fourmann J.B., Schmitzová J., Christian H., Urlaub H., Ficner R., Boon K.L., Fabrizio P., Lührmann R. Dissection of the factor requirements for spliceosome disassembly and the elucidation of its dissociation products using a purified splicing system. Genes Dev 2013, 27:413-428.
-
(2013)
Genes Dev
, vol.27
, pp. 413-428
-
-
Fourmann, J.B.1
Schmitzová, J.2
Christian, H.3
Urlaub, H.4
Ficner, R.5
Boon, K.L.6
Fabrizio, P.7
Lührmann, R.8
-
13
-
-
84894250615
-
Endogenous U2·U5·U6 snRNA complexes in S. pombe are intron lariat spliceosomes
-
Chen W., Shulha H.P., Ashar-Patel A., Yan J., Green K.M., Query C.C., Rhind N., Weng Z., Moore M.J. Endogenous U2·U5·U6 snRNA complexes in S. pombe are intron lariat spliceosomes. RNA 2014, 20:308-320.
-
(2014)
RNA
, vol.20
, pp. 308-320
-
-
Chen, W.1
Shulha, H.P.2
Ashar-Patel, A.3
Yan, J.4
Green, K.M.5
Query, C.C.6
Rhind, N.7
Weng, Z.8
Moore, M.J.9
-
14
-
-
84879311174
-
Molecular dissection of step 2 catalysis of yeast pre-mRNA splicing investigated in a purified system
-
Ohrt T., Odenwälder P., Dannenberg J., Prior M., Warkocki Z., Schmitzová J., Karaduman R., Gregor I., Enderlein J., Fabrizio P., Lührmann R. Molecular dissection of step 2 catalysis of yeast pre-mRNA splicing investigated in a purified system. RNA 2013, 19:902-915.
-
(2013)
RNA
, vol.19
, pp. 902-915
-
-
Ohrt, T.1
Odenwälder, P.2
Dannenberg, J.3
Prior, M.4
Warkocki, Z.5
Schmitzová, J.6
Karaduman, R.7
Gregor, I.8
Enderlein, J.9
Fabrizio, P.10
Lührmann, R.11
-
15
-
-
84861984263
-
Structure, function and regulation of spliceosomal RNA helicases
-
Cordin O., Hahn D., Beggs J.D. Structure, function and regulation of spliceosomal RNA helicases. Curr Opin Cell Biol 2012, 24:431-438.
-
(2012)
Curr Opin Cell Biol
, vol.24
, pp. 431-438
-
-
Cordin, O.1
Hahn, D.2
Beggs, J.D.3
-
16
-
-
63649099704
-
Crystal structure of human spliceosomal U1 snRNP at 5.5Å resolution
-
Pomeranz Krummel D.A., Oubridge C., Leung A.K., Li J., Nagai K. Crystal structure of human spliceosomal U1 snRNP at 5.5Å resolution. Nature 2009, 458:475-480.
-
(2009)
Nature
, vol.458
, pp. 475-480
-
-
Pomeranz Krummel, D.A.1
Oubridge, C.2
Leung, A.K.3
Li, J.4
Nagai, K.5
-
17
-
-
84922041769
-
Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5' splice site recognition
-
Kondo Y., Oubridge C., van Roon A.M., Nagai K. Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5' splice site recognition. eLife 2015, 10.7554/eLife.04986.
-
(2015)
eLife
-
-
Kondo, Y.1
Oubridge, C.2
van Roon, A.M.3
Nagai, K.4
-
18
-
-
33745050151
-
Cryo-electron microscopy of spliceosomal components
-
Stark H., Lührmann R. Cryo-electron microscopy of spliceosomal components. Annu Rev Biophys Biomol Struct 2006, 35:435-457.
-
(2006)
Annu Rev Biophys Biomol Struct
, vol.35
, pp. 435-457
-
-
Stark, H.1
Lührmann, R.2
-
19
-
-
55549142496
-
Localization of Prp8, Brr2, Snu114 and U4/U6 proteins in the yeast tri-snRNP by electron microscopy
-
Häcker I., Sander B., Golas M.M., Wolf E., Karagöz E., Kastner B., Stark H., Fabrizio P., Lührmann R. Localization of Prp8, Brr2, Snu114 and U4/U6 proteins in the yeast tri-snRNP by electron microscopy. Nat Struct Mol Biol 2008, 15:1206-1212.
-
(2008)
Nat Struct Mol Biol
, vol.15
, pp. 1206-1212
-
-
Häcker, I.1
Sander, B.2
Golas, M.M.3
Wolf, E.4
Karagöz, E.5
Kastner, B.6
Stark, H.7
Fabrizio, P.8
Lührmann, R.9
-
20
-
-
38849192403
-
A protein-based EM label for RNA identifies the location of exons in spliceosomes
-
Alcid E.A., Jurica M.S. A protein-based EM label for RNA identifies the location of exons in spliceosomes. Nat Struct Mol Biol 2008, 15:213-215.
-
(2008)
Nat Struct Mol Biol
, vol.15
, pp. 213-215
-
-
Alcid, E.A.1
Jurica, M.S.2
-
21
-
-
68249149579
-
Exon, intron and splice site locations in the spliceosomal B complex
-
Wolf E., Kastner B., Deckert J., Merz C., Stark H., Lührmann R. Exon, intron and splice site locations in the spliceosomal B complex. EMBO J 2009, 28:2283-2292.
-
(2009)
EMBO J
, vol.28
, pp. 2283-2292
-
-
Wolf, E.1
Kastner, B.2
Deckert, J.3
Merz, C.4
Stark, H.5
Lührmann, R.6
-
23
-
-
84938513943
-
The architecture of the spliceosomal U4/U6.U5 tri-snRNP
-
Nguyen T.H., Galej W.P., Bai X.C., Savva C.G., Newman A.J., Scheres S.H., Nagai K. The architecture of the spliceosomal U4/U6.U5 tri-snRNP. Nature 2015, 523:47-52.
-
(2015)
Nature
, vol.523
, pp. 47-52
-
-
Nguyen, T.H.1
Galej, W.P.2
Bai, X.C.3
Savva, C.G.4
Newman, A.J.5
Scheres, S.H.6
Nagai, K.7
-
24
-
-
84942474131
-
Structure of a yeast spliceosome at 3.6-angstrom resolution
-
Yan C., Hang J., Wan R., Huang M., Wong C.C., Shi Y. Structure of a yeast spliceosome at 3.6-angstrom resolution. Science 2015, 349:1182-1191.
-
(2015)
Science
, vol.349
, pp. 1182-1191
-
-
Yan, C.1
Hang, J.2
Wan, R.3
Huang, M.4
Wong, C.C.5
Shi, Y.6
-
25
-
-
33847688429
-
Structural characterization of the fission yeast U5.U2/U6 spliceosome complex
-
Ohi M.D., Ren L., Wall J.S., Gould K.L., Walz T. Structural characterization of the fission yeast U5.U2/U6 spliceosome complex. Proc Natl Acad Sci U S A 2007, 104:3195-3200.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 3195-3200
-
-
Ohi, M.D.1
Ren, L.2
Wall, J.S.3
Gould, K.L.4
Walz, T.5
-
26
-
-
33749672830
-
Organization of core spliceosomal components U5 snRNA loop I and U4/U6 Di-snRNP within U4/U6.U5 Tri-snRNP as revealed by electron cryomicroscopy
-
Sander B., Golas M.M., Makarov E.M., Brahms H., Kastner B., Lührmann R., Stark H. Organization of core spliceosomal components U5 snRNA loop I and U4/U6 Di-snRNP within U4/U6.U5 Tri-snRNP as revealed by electron cryomicroscopy. Mol Cell 2006, 24:267-278.
-
(2006)
Mol Cell
, vol.24
, pp. 267-278
-
-
Sander, B.1
Golas, M.M.2
Makarov, E.M.3
Brahms, H.4
Kastner, B.5
Lührmann, R.6
Stark, H.7
-
27
-
-
2342539773
-
Three-dimensional structure of a pre-catalytic human spliceosomal complex B
-
Boehringer D., Makarov E.M., Sander B., Makarova O.V., Kastner B., Lührmann R., Stark H. Three-dimensional structure of a pre-catalytic human spliceosomal complex B. Nat Struct Mol Biol 2004, 11:463-468.
-
(2004)
Nat Struct Mol Biol
, vol.11
, pp. 463-468
-
-
Boehringer, D.1
Makarov, E.M.2
Sander, B.3
Makarova, O.V.4
Kastner, B.5
Lührmann, R.6
Stark, H.7
-
28
-
-
33745860086
-
Protein composition and electron microscopy structure of affinity-purified human spliceosomal B complexes isolated under physiological conditions
-
Deckert J., Hartmuth K., Boehringer D., Behzadnia N., Will C.L., Kastner B., Stark H., Urlaub H., Lührmann R. Protein composition and electron microscopy structure of affinity-purified human spliceosomal B complexes isolated under physiological conditions. Mol Cell Biol 2006, 26:5528-5543.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 5528-5543
-
-
Deckert, J.1
Hartmuth, K.2
Boehringer, D.3
Behzadnia, N.4
Will, C.L.5
Kastner, B.6
Stark, H.7
Urlaub, H.8
Lührmann, R.9
-
29
-
-
0035161567
-
Biochemical and genetic analyses of the U5 U6, and U4/U6×U5 small nuclear ribonucleoproteins from Saccharomyces cerevisiae
-
Stevens S.W., Barta I., Ge H.Y., Moore R.E., Young M.K., Lee T.D., Abelson J. Biochemical and genetic analyses of the U5 U6, and U4/U6×U5 small nuclear ribonucleoproteins from Saccharomyces cerevisiae. RNA 2001, 7:1543-1553.
-
(2001)
RNA
, vol.7
, pp. 1543-1553
-
-
Stevens, S.W.1
Barta, I.2
Ge, H.Y.3
Moore, R.E.4
Young, M.K.5
Lee, T.D.6
Abelson, J.7
-
30
-
-
0033575711
-
Identification by mass spectrometry and functional analysis of novel proteins of the yeast [U4/U6.U5] tri-snRNP
-
Gottschalk A., Neubauer G., Banroques J., Mann M., Lührmann R., Fabrizio P. Identification by mass spectrometry and functional analysis of novel proteins of the yeast [U4/U6.U5] tri-snRNP. EMBO J 1999, 18:4535-4548.
-
(1999)
EMBO J
, vol.18
, pp. 4535-4548
-
-
Gottschalk, A.1
Neubauer, G.2
Banroques, J.3
Mann, M.4
Lührmann, R.5
Fabrizio, P.6
-
31
-
-
0031741144
-
The human U5-220kD protein (hPrp8) forms a stable RNA-free complex with several U5-specific proteins, including an RNA unwindase, a homologue of ribosomal elongation factor EF-2, and a novel WD-40 protein
-
Achsel T., Ahrens K., Brahms H., Teigelkamp S., Lührmann R. The human U5-220kD protein (hPrp8) forms a stable RNA-free complex with several U5-specific proteins, including an RNA unwindase, a homologue of ribosomal elongation factor EF-2, and a novel WD-40 protein. Mol Cell Biol 1998, 18:6756-6766.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 6756-6766
-
-
Achsel, T.1
Ahrens, K.2
Brahms, H.3
Teigelkamp, S.4
Lührmann, R.5
-
32
-
-
17844395704
-
Prp8 protein: at the heart of the spliceosome
-
Grainger R.J., Beggs J.D. Prp8 protein: at the heart of the spliceosome. RNA 2005, 11:533-557.
-
(2005)
RNA
, vol.11
, pp. 533-557
-
-
Grainger, R.J.1
Beggs, J.D.2
-
33
-
-
0032537739
-
RNA unwinding in U4/U6 snRNPs requires ATP hydrolysis and the DEIH-box splicing factor Brr2
-
Raghunathan P.L., Guthrie C. RNA unwinding in U4/U6 snRNPs requires ATP hydrolysis and the DEIH-box splicing factor Brr2. Curr Biol 1998, 8:847-855.
-
(1998)
Curr Biol
, vol.8
, pp. 847-855
-
-
Raghunathan, P.L.1
Guthrie, C.2
-
34
-
-
69149090973
-
Common design principles in the spliceosomal RNA helicase Brr2 and in the Hel308 DNA helicase
-
Pena V., Jovin S.M., Fabrizio P., Orlowski J., Bujnicki J.M., Lührmann R., Wahl M.C. Common design principles in the spliceosomal RNA helicase Brr2 and in the Hel308 DNA helicase. Mol Cell 2009, 35:454-466.
-
(2009)
Mol Cell
, vol.35
, pp. 454-466
-
-
Pena, V.1
Jovin, S.M.2
Fabrizio, P.3
Orlowski, J.4
Bujnicki, J.M.5
Lührmann, R.6
Wahl, M.C.7
-
35
-
-
67650296697
-
Structural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2
-
Zhang L., Xu T., Maeder C., Bud L.O., Shanks J., Nix J., Guthrie C., Pleiss J.A., Zhao R. Structural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2. Nat Struct Mol Biol 2009, 16:731-739.
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 731-739
-
-
Zhang, L.1
Xu, T.2
Maeder, C.3
Bud, L.O.4
Shanks, J.5
Nix, J.6
Guthrie, C.7
Pleiss, J.A.8
Zhao, R.9
-
36
-
-
84867913431
-
Structural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosome
-
Santos K.F., Jovin S.M., Weber G., Pena V., Lührmann R., Wahl M.C. Structural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosome. Proc Natl Acad Sci U S A 2012, 109:17418-17423.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 17418-17423
-
-
Santos, K.F.1
Jovin, S.M.2
Weber, G.3
Pena, V.4
Lührmann, R.5
Wahl, M.C.6
-
37
-
-
84878849387
-
Structural basis of Brr2-Prp8 interactions and implications for U5 snRNP biogenesis and the spliceosome active site
-
Nguyen T.H., Li J., Galej W.P., Oshikane H., Newman A.J., Nagai K. Structural basis of Brr2-Prp8 interactions and implications for U5 snRNP biogenesis and the spliceosome active site. Structure 2013, 21:910-919.
-
(2013)
Structure
, vol.21
, pp. 910-919
-
-
Nguyen, T.H.1
Li, J.2
Galej, W.P.3
Oshikane, H.4
Newman, A.J.5
Nagai, K.6
-
38
-
-
0030976931
-
An evolutionarily conserved U5 snRNP-specific protein is a GTP-binding factor closely related to the ribosomal translocase EF-2
-
Fabrizio P., Laggerbauer B., Lauber J., Lane W.S., Lührmann R. An evolutionarily conserved U5 snRNP-specific protein is a GTP-binding factor closely related to the ribosomal translocase EF-2. EMBO J 1997, 16:4092-4106.
-
(1997)
EMBO J
, vol.16
, pp. 4092-4106
-
-
Fabrizio, P.1
Laggerbauer, B.2
Lauber, J.3
Lane, W.S.4
Lührmann, R.5
-
39
-
-
0242516080
-
Two crystal structures demonstrate large conformational changes in the eukaryotic ribosomal translocase
-
Jørgensen R., Ortiz P.A., Carr-Schmid A., Nissen P., Kinzy T.G., Andersen G.R. Two crystal structures demonstrate large conformational changes in the eukaryotic ribosomal translocase. Nat Struct Biol 2003, 10:379-385.
-
(2003)
Nat Struct Biol
, vol.10
, pp. 379-385
-
-
Jørgensen, R.1
Ortiz, P.A.2
Carr-Schmid, A.3
Nissen, P.4
Kinzy, T.G.5
Andersen, G.R.6
-
40
-
-
33746441457
-
The EF-G-like GTPase Snu114p regulates spliceosome dynamics mediated by Brr2p, a DExD/H box ATPase
-
Small E.C., Leggett S.R., Winans A.A., Staley J.P. The EF-G-like GTPase Snu114p regulates spliceosome dynamics mediated by Brr2p, a DExD/H box ATPase. Mol Cell 2006, 23:389-399.
-
(2006)
Mol Cell
, vol.23
, pp. 389-399
-
-
Small, E.C.1
Leggett, S.R.2
Winans, A.A.3
Staley, J.P.4
-
41
-
-
0041344523
-
Mutagenesis suggests several roles of Snu114p in pre-mRNA splicing
-
Bartels C., Urlaub H., Lührmann R., Fabrizio P. Mutagenesis suggests several roles of Snu114p in pre-mRNA splicing. J Biol Chem 2003, 278:28324-28334.
-
(2003)
J Biol Chem
, vol.278
, pp. 28324-28334
-
-
Bartels, C.1
Urlaub, H.2
Lührmann, R.3
Fabrizio, P.4
-
42
-
-
84873629024
-
Crystal structure of Prp8 reveals active site cavity of the spliceosome
-
Galej W.P., Oubridge C., Newman A.J., Nagai K. Crystal structure of Prp8 reveals active site cavity of the spliceosome. Nature 2013, 493:638-643.
-
(2013)
Nature
, vol.493
, pp. 638-643
-
-
Galej, W.P.1
Oubridge, C.2
Newman, A.J.3
Nagai, K.4
-
43
-
-
35848950003
-
Prp8 mutations that cause human retinitis pigmentosa lead to a U5 snRNP maturation defect in yeast
-
Boon K.L., Grainger R.J., Ehsani P., Barrass J.D., Auchynnikava T., Inglehearn C.F., Beggs J.D. Prp8 mutations that cause human retinitis pigmentosa lead to a U5 snRNP maturation defect in yeast. Nat Struct Mol Biol 2007, 14:1077-1083.
-
(2007)
Nat Struct Mol Biol
, vol.14
, pp. 1077-1083
-
-
Boon, K.L.1
Grainger, R.J.2
Ehsani, P.3
Barrass, J.D.4
Auchynnikava, T.5
Inglehearn, C.F.6
Beggs, J.D.7
-
44
-
-
84879797997
-
Inhibition of RNA helicase Brr2 by the C-terminal tail of the spliceosomal protein Prp8
-
Mozaffari-Jovin S., Wandersleben T., Santos K.F., Will C.L., Lührmann R., Wahl M.C. Inhibition of RNA helicase Brr2 by the C-terminal tail of the spliceosomal protein Prp8. Science 2013, 341:80-84.
-
(2013)
Science
, vol.341
, pp. 80-84
-
-
Mozaffari-Jovin, S.1
Wandersleben, T.2
Santos, K.F.3
Will, C.L.4
Lührmann, R.5
Wahl, M.C.6
-
45
-
-
31044438832
-
Prp8p dissection reveals domain structure and protein interaction sites
-
Boon K.L., Norman C.M., Grainger R.J., Newman A.J., Beggs J.D. Prp8p dissection reveals domain structure and protein interaction sites. RNA 2006, 12:198-205.
-
(2006)
RNA
, vol.12
, pp. 198-205
-
-
Boon, K.L.1
Norman, C.M.2
Grainger, R.J.3
Newman, A.J.4
Beggs, J.D.5
-
46
-
-
73249134403
-
Physical and genetic interactions of yeast Cwc21p, an ortholog of human SRm300/SRRM2, suggest a role at the catalytic center of the spliceosome
-
Grainger R.J., Barrass J.D., Jacquier A., Rain J.C., Beggs J.D. Physical and genetic interactions of yeast Cwc21p, an ortholog of human SRm300/SRRM2, suggest a role at the catalytic center of the spliceosome. RNA 2009, 15:2161-2173.
-
(2009)
RNA
, vol.15
, pp. 2161-2173
-
-
Grainger, R.J.1
Barrass, J.D.2
Jacquier, A.3
Rain, J.C.4
Beggs, J.D.5
-
47
-
-
0037107418
-
Hierarchical, clustered protein interactions with U4/U6 snRNA: a biochemical role for U4/U6 proteins
-
Nottrott S., Urlaub H., Lührmann R. Hierarchical, clustered protein interactions with U4/U6 snRNA: a biochemical role for U4/U6 proteins. EMBO J 2002, 21:5527-5538.
-
(2002)
EMBO J
, vol.21
, pp. 5527-5538
-
-
Nottrott, S.1
Urlaub, H.2
Lührmann, R.3
-
48
-
-
34147095881
-
Binding of the human Prp31 Nop domain to a composite RNA-protein platform in U4 snRNP
-
Liu S., Li P., Dybkov O., Nottrott S., Hartmuth K., Lührmann R., Carlomagno T., Wahl M.C. Binding of the human Prp31 Nop domain to a composite RNA-protein platform in U4 snRNP. Science 2007, 316:115-120.
-
(2007)
Science
, vol.316
, pp. 115-120
-
-
Liu, S.1
Li, P.2
Dybkov, O.3
Nottrott, S.4
Hartmuth, K.5
Lührmann, R.6
Carlomagno, T.7
Wahl, M.C.8
-
49
-
-
84954467080
-
Assembly and dynamics of the U4/U6 di-snRNP by single-molecule FRET
-
(in press)
-
Hardin J.W., Warnasooriya C., Kondo Y., Nagai K., Rueda D. Assembly and dynamics of the U4/U6 di-snRNP by single-molecule FRET. Nucleic Acids Res 2015, (in press).
-
(2015)
Nucleic Acids Res
-
-
Hardin, J.W.1
Warnasooriya, C.2
Kondo, Y.3
Nagai, K.4
Rueda, D.5
-
50
-
-
0032484029
-
Functional and structural characterization of the prp3 binding domain of the yeast prp4 splicing factor
-
Ayadi L., Callebaut I., Saguez C., Villa T., Mornon J.P., Banroques J. Functional and structural characterization of the prp3 binding domain of the yeast prp4 splicing factor. J Mol Biol 1998, 284:673-687.
-
(1998)
J Mol Biol
, vol.284
, pp. 673-687
-
-
Ayadi, L.1
Callebaut, I.2
Saguez, C.3
Villa, T.4
Mornon, J.P.5
Banroques, J.6
-
51
-
-
84938309511
-
A composite double-/single-stranded RNA-binding region in protein Prp3 supports tri-snRNP stability and splicing
-
Liu S., Mozaffari-Jovin S., Wollenhaupt J., Santos K.F., Theuser M., Dunin-Horkawicz S., Fabrizio P., Bujnicki J.M., Lührmann R., Wahl M.C. A composite double-/single-stranded RNA-binding region in protein Prp3 supports tri-snRNP stability and splicing. eLife 2015, 10.7554/eLife.07320.
-
(2015)
eLife
-
-
Liu, S.1
Mozaffari-Jovin, S.2
Wollenhaupt, J.3
Santos, K.F.4
Theuser, M.5
Dunin-Horkawicz, S.6
Fabrizio, P.7
Bujnicki, J.M.8
Lührmann, R.9
Wahl, M.C.10
-
52
-
-
84868592766
-
Brr2p-mediated conformational rearrangements in the spliceosome during activation and substrate repositioning
-
Hahn D., Kudla G., Tollervey D., Beggs J.D. Brr2p-mediated conformational rearrangements in the spliceosome during activation and substrate repositioning. Genes Dev 2012, 26:2408-2421.
-
(2012)
Genes Dev
, vol.26
, pp. 2408-2421
-
-
Hahn, D.1
Kudla, G.2
Tollervey, D.3
Beggs, J.D.4
-
53
-
-
84868583242
-
The Prp8 RNase H-like domain inhibits Brr2-mediated U4/U6 snRNA unwinding by blocking Brr2 loading onto the U4 snRNA
-
Mozaffari-Jovin S., Santos K.F., Hsiao H.H., Will C.L., Urlaub H., Wahl M.C., Lührmann R. The Prp8 RNase H-like domain inhibits Brr2-mediated U4/U6 snRNA unwinding by blocking Brr2 loading onto the U4 snRNA. Genes Dev 2012, 26:2422-2434.
-
(2012)
Genes Dev
, vol.26
, pp. 2422-2434
-
-
Mozaffari-Jovin, S.1
Santos, K.F.2
Hsiao, H.H.3
Will, C.L.4
Urlaub, H.5
Wahl, M.C.6
Lührmann, R.7
-
54
-
-
33344460290
-
Dissection of Prp8 protein defines multiple interactions with crucial RNA sequences in the catalytic core of the spliceosome
-
Turner I.A., Norman C.M., Churcher M.J., Newman A.J. Dissection of Prp8 protein defines multiple interactions with crucial RNA sequences in the catalytic core of the spliceosome. RNA 2006, 12:375-386.
-
(2006)
RNA
, vol.12
, pp. 375-386
-
-
Turner, I.A.1
Norman, C.M.2
Churcher, M.J.3
Newman, A.J.4
-
55
-
-
84942913896
-
Structural basis of pre-mRNA splicing
-
Hang J., Wan R., Yan C., Shi Y. Structural basis of pre-mRNA splicing. Science 2015, 349:1191-1198.
-
(2015)
Science
, vol.349
, pp. 1191-1198
-
-
Hang, J.1
Wan, R.2
Yan, C.3
Shi, Y.4
-
56
-
-
79952239719
-
Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19
-
Ren L., McLean J.R., Hazbun T.R., Fields S., Vander Kooi C., Ohi M.D., Gould K.L. Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19. PLoS One 2011, 6:e16719.
-
(2011)
PLoS One
, vol.6
, pp. e16719
-
-
Ren, L.1
McLean, J.R.2
Hazbun, T.R.3
Fields, S.4
Vander Kooi, C.5
Ohi, M.D.6
Gould, K.L.7
-
57
-
-
0027468210
-
PRP19: a novel spliceosomal component
-
Cheng S.C., Tarn W.Y., Tsao T.Y., Abelson J. PRP19: a novel spliceosomal component. Mol Cell Biol 1993, 13:1876-1882.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 1876-1882
-
-
Cheng, S.C.1
Tarn, W.Y.2
Tsao, T.Y.3
Abelson, J.4
-
58
-
-
0037082435
-
Functional and physical interaction between components of the Prp19p-associated complex
-
Chen C.H., Yu W.C., Tsao T.Y., Wang L.Y., Chen H.R., Lin J.Y., Tsai W.Y., Cheng S.C. Functional and physical interaction between components of the Prp19p-associated complex. Nucleic Acids Res 2002, 30:1029-1037.
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 1029-1037
-
-
Chen, C.H.1
Yu, W.C.2
Tsao, T.Y.3
Wang, L.Y.4
Chen, H.R.5
Lin, J.Y.6
Tsai, W.Y.7
Cheng, S.C.8
-
59
-
-
0036269649
-
Characterization of interactions among the Cef1p-Prp19p-associated splicing complex
-
Ohi M.D., Gould K.L. Characterization of interactions among the Cef1p-Prp19p-associated splicing complex. RNA 2002, 8:798-815.
-
(2002)
RNA
, vol.8
, pp. 798-815
-
-
Ohi, M.D.1
Gould, K.L.2
-
60
-
-
11144320747
-
Structural and functional analysis of essential pre-mRNA splicing factor Prp19p
-
Ohi M.D., Vander Kooi C.W., Rosenberg J.A., Ren L., Hirsch J.P., Chazin W.J., Walz T., Gould K.L. Structural and functional analysis of essential pre-mRNA splicing factor Prp19p. Mol Cell Biol 2005, 25:451-460.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 451-460
-
-
Ohi, M.D.1
Vander Kooi, C.W.2
Rosenberg, J.A.3
Ren, L.4
Hirsch, J.P.5
Chazin, W.J.6
Walz, T.7
Gould, K.L.8
-
61
-
-
3242737496
-
A subset of human 35S U5 proteins, including Prp19, function prior to catalytic step 1 of splicing
-
Makarova O.V., Makarov E.M., Urlaub H., Will C.L., Gentzel M., Wilm M., Lührmann R. A subset of human 35S U5 proteins, including Prp19, function prior to catalytic step 1 of splicing. EMBO J 2004, 23:2381-2391.
-
(2004)
EMBO J
, vol.23
, pp. 2381-2391
-
-
Makarova, O.V.1
Makarov, E.M.2
Urlaub, H.3
Will, C.L.4
Gentzel, M.5
Wilm, M.6
Lührmann, R.7
-
62
-
-
77952666620
-
The Prp19 WD40 domain contains a conserved protein interaction region essential for its function
-
Vander Kooi C.W., Ren L., Xu P., Ohi M.D., Gould K.L., Chazin W.J. The Prp19 WD40 domain contains a conserved protein interaction region essential for its function. Structure 2010, 18:584-593.
-
(2010)
Structure
, vol.18
, pp. 584-593
-
-
Vander Kooi, C.W.1
Ren, L.2
Xu, P.3
Ohi, M.D.4
Gould, K.L.5
Chazin, W.J.6
-
63
-
-
84926421065
-
The RNA helicase Aquarius exhibits structural adaptations mediating its recruitment to spliceosomes
-
De I., Bessonov S., Hofele R., dos Santos K., Will C.L., Urlaub H., Lührmann R., Pena V. The RNA helicase Aquarius exhibits structural adaptations mediating its recruitment to spliceosomes. Nat Struct Mol Biol 2015, 22:138-144.
-
(2015)
Nat Struct Mol Biol
, vol.22
, pp. 138-144
-
-
De, I.1
Bessonov, S.2
Hofele, R.3
dos Santos, K.4
Will, C.L.5
Urlaub, H.6
Lührmann, R.7
Pena, V.8
-
64
-
-
0027184481
-
A general two-metal-ion mechanism for catalytic RNA
-
Steitz T.A., Steitz J.A. A general two-metal-ion mechanism for catalytic RNA. Proc Natl Acad Sci USA 1993, 90:6498-6502.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 6498-6502
-
-
Steitz, T.A.1
Steitz, J.A.2
-
65
-
-
84904513583
-
A homolog of lariat-debranching enzyme modulates turnover of branched RNA
-
Garrey S.M., Katolik A., Prekeris M., Li X., York K., Bernards S., Fields S., Zhao R., Damha M.J., Hesselberth J.R. A homolog of lariat-debranching enzyme modulates turnover of branched RNA. RNA 2014, 20:1337-1348.
-
(2014)
RNA
, vol.20
, pp. 1337-1348
-
-
Garrey, S.M.1
Katolik, A.2
Prekeris, M.3
Li, X.4
York, K.5
Bernards, S.6
Fields, S.7
Zhao, R.8
Damha, M.J.9
Hesselberth, J.R.10
-
66
-
-
84858799296
-
Cwc2 and its human homologue RBM22 promote an active conformation of the spliceosome catalytic centre
-
Rasche N., Dybkov O., Schmitzova J., Akyildiz B., Fabrizio P., Lührmann R. Cwc2 and its human homologue RBM22 promote an active conformation of the spliceosome catalytic centre. EMBO J 2012, 31:1591-1604.
-
(2012)
EMBO J
, vol.31
, pp. 1591-1604
-
-
Rasche, N.1
Dybkov, O.2
Schmitzova, J.3
Akyildiz, B.4
Fabrizio, P.5
Lührmann, R.6
-
67
-
-
84860540204
-
Crystal structure of Cwc2 reveals a novel architecture of a multipartite RNA-binding protein
-
Schmitzova J., Rasche N., Dybkov O., Kramer K., Fabrizio P., Henning U., Lührmann R., Pena V. Crystal structure of Cwc2 reveals a novel architecture of a multipartite RNA-binding protein. EMBO J 2012, 31:2222-2234.
-
(2012)
EMBO J
, vol.31
, pp. 2222-2234
-
-
Schmitzova, J.1
Rasche, N.2
Dybkov, O.3
Kramer, K.4
Fabrizio, P.5
Henning, U.6
Lührmann, R.7
Pena, V.8
-
68
-
-
70449625597
-
The evolutionarily conserved core design of the catalytic activation step of the yeast spliceosome
-
Fabrizio P., Dannenberg J., Dube P., Kastner B., Stark H., Urlaub H., Lührmann R. The evolutionarily conserved core design of the catalytic activation step of the yeast spliceosome. Mol Cell 2009, 36:593-608.
-
(2009)
Mol Cell
, vol.36
, pp. 593-608
-
-
Fabrizio, P.1
Dannenberg, J.2
Dube, P.3
Kastner, B.4
Stark, H.5
Urlaub, H.6
Lührmann, R.7
-
69
-
-
84863363427
-
Structure of the yeast U2/U6 snRNA complex
-
Burke J.E., Sashital D.G., Zuo X., Wang Y.X., Butcher S.E. Structure of the yeast U2/U6 snRNA complex. RNA 2012, 18:673-683.
-
(2012)
RNA
, vol.18
, pp. 673-683
-
-
Burke, J.E.1
Sashital, D.G.2
Zuo, X.3
Wang, Y.X.4
Butcher, S.E.5
-
70
-
-
78649650270
-
3D cryo-EM structure of an active step I spliceosome and localization of its catalytic core
-
Golas M.M., Sander B., Bessonov S., Grote M., Wolf E., Kastner B., Stark H., Lührmann R. 3D cryo-EM structure of an active step I spliceosome and localization of its catalytic core. Mol Cell 2010, 40:927-938.
-
(2010)
Mol Cell
, vol.40
, pp. 927-938
-
-
Golas, M.M.1
Sander, B.2
Bessonov, S.3
Grote, M.4
Wolf, E.5
Kastner, B.6
Stark, H.7
Lührmann, R.8
-
71
-
-
84868035651
-
Visualizing group II intron catalysis through the stages of splicing
-
Marcia M., Pyle A.M. Visualizing group II intron catalysis through the stages of splicing. Cell 2012, 151:497-507.
-
(2012)
Cell
, vol.151
, pp. 497-507
-
-
Marcia, M.1
Pyle, A.M.2
-
72
-
-
84908347683
-
Crystal structure of a eukaryotic group II intron lariat
-
Robart A.R., Chan R.T., Peters J.K., Rajashankar K.R., Toor N. Crystal structure of a eukaryotic group II intron lariat. Nature 2014, 514:193-197.
-
(2014)
Nature
, vol.514
, pp. 193-197
-
-
Robart, A.R.1
Chan, R.T.2
Peters, J.K.3
Rajashankar, K.R.4
Toor, N.5
|