Functional and physical interactions between components of the Prp19p-associated complex

Nucleic Acids Research

Volumn 30, Issue 4, 2002, Pages 1029-1037

  Chen, Chun Hong ^a,b   Yu, Wan Chin ^a,c   Tsao, Twee Y ^a   Wang, Lian Yung ^a,b   Chen, Hau Ren ^a,d   Lin, Jui Yen ^a   Tsai, Wei Yü ^a,b,e   Cheng, Soo Chen ^a,b  

^a INSTITUTE OF MOLECULAR BIOLOGY   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c DEVELOPMENT CENTER FOR BIOTECHNOLOGY   (Taiwan)

^d UNIVERSITY OF WISCONSIN MADISON   (United States)

^e CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

FUNGAL PROTEIN; MESSENGER RNA; PROTEIN NTC20P; PROTEIN NTC25P; PROTEIN NTC30P; PROTEIN NTC31P; PROTEIN NTC77P; PROTEIN NTC85P; PROTEIN NTC90P; PROTEIN PRP19P; SMALL NUCLEAR RNA; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

COMPLEX FORMATION; CONTROLLED STUDY; GENETIC ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REVIEW; RNA SPLICING; TWO HYBRID SYSTEM; YEAST;

EID: 0037082435     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/30.4.1029     Document Type: Review

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15. The DEAH-box protein PRP22 is an ATPase that mediates ATP-dependent mRNA release from the spliceosome and unwinds RNA duplexes
16. The DEAH-box splicing factor Prp16 unwinds RNA duplexes in vitro
17. Specific alterations of U1-C protein or U1 small nuclear RNA can eliminate the requirement of Prp28p, an essential DEAD box splicing factor
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19. An RNA switch at the 5′ splice site requires ATP and the DEAD box protein Prp28p
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21. Yeast precursor mRNA processing protein PRP19 associates with the spliceosome concomitant with or just after dissociation of U4 small nuclear RNA
22. Functional association of essential splicing factor(s) with PRP19 in a protein complex
23. Snt309p, a component of the Prp19p-associated complex that interacts with Prp19p and associates with the spliceosome simultaneously with or immediately after dissociation of U4 in the same manner as Prp19p
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27. Myb-related Schizosaccharomyces pombe cdc5p is structurally and functionally conserved in eukaryotes
28. Snt309p modulates interactions of Prp19p with its associated components to stabilize the Prp19p-associated complex essential for pre-mRNA splicing
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34. The PRP4 (RNA4) protein of Saccharomyces cerevisiae is associated with the 5′ portion of the U4 snRNA
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42. Yeast ortholog of the Drosophila crooked neck protein promotes spliceosome assembly through stable U4/U6.U5 snRNP addition
43. Requirement of the RNA helicase-like protein PRP22 for release of messenger RNA from spliceosomes
44. Prp22, a DExH-box RNA helicase, plays two distinct roles in yeast pre-mRNA splicing