메뉴 건너뛰기




Volumn 358, Issue 1, 2016, Pages 3-25

Why Does Industry Not Use Immobilized Transition Metal Complexes as Catalysts?

Author keywords

homogeneous catalysis; hydrogenation; immobilization; metathesis; palladium

Indexed keywords


EID: 84954380924     PISSN: 16154150     EISSN: 16154169     Source Type: Journal    
DOI: 10.1002/adsc.201500846     Document Type: Review
Times cited : (343)

References (191)
  • 8
    • 34548728077 scopus 로고    scopus 로고
    • Angew. Chem. Int. Ed. 2007, 46, 6786-6801.
    • (2007) Angew. Chem. Int. Ed. , vol.46 , pp. 6786-6801
  • 10
    • 84902545004 scopus 로고    scopus 로고
    • Several examples of metathesis in flow have been described. See, among others:, One major problem with these proofs of concept is that, once again, the TON problem is not addressed and a meaningful comparison with batch reactions is not carried out. Unavoidable progressive catalyst deactivation leads to limited column usefulness and necessitates sophisticated in-process control tools. However, as thoroughly documented in many reviews, flow chemistry using immobilized catalysts can give rise to novel kinetic phenomena which are sometimes advantageous and yield potential improvements that are not available with the same immobilized catalysts in batch mode. See, e.g
    • Several examples of metathesis in flow have been described. See, among others:, J. Gmeiner, M. Seibicke, C. Lang, U. Gärtner, O. Trapp, Adv. Synth. Catal. 2014, 356, 2081-2087. One major problem with these proofs of concept is that, once again, the TON problem is not addressed and a meaningful comparison with batch reactions is not carried out. Unavoidable progressive catalyst deactivation leads to limited column usefulness and necessitates sophisticated in-process control tools. However, as thoroughly documented in many reviews, flow chemistry using immobilized catalysts can give rise to novel kinetic phenomena which are sometimes advantageous and yield potential improvements that are not available with the same immobilized catalysts in batch mode. See, e.g
    • (2014) Adv. Synth. Catal. , vol.356 , pp. 2081-2087
    • Gmeiner, J.1    Seibicke, M.2    Lang, C.3    Gärtner, U.4    Trapp, O.5
  • 14
    • 0034602069 scopus 로고    scopus 로고
    • Angew. Chem. Int. Ed. 2000, 39, 3898-3901.
    • (2000) Angew. Chem. Int. Ed. , vol.39 , pp. 3898-3901
  • 42
    • 0035915174 scopus 로고    scopus 로고
    • Angew. Chem. Int. Ed. 2001, 40, 4251-4256.
    • (2001) Angew. Chem. Int. Ed. , vol.40 , pp. 4251-4256
  • 46
    • 0037131458 scopus 로고    scopus 로고
    • Angew. Chem. Int. Ed. 2002, 41, 3835-3838.
    • (2002) Angew. Chem. Int. Ed. , vol.41 , pp. 3835-3838
  • 55
    • 0043031400 scopus 로고    scopus 로고
    • Angew. Chem. Int. Ed. 2003, 42, 3395-3398;
    • (2003) Angew. Chem. Int. Ed. , vol.42 , pp. 3395-3398
  • 58
    • 34447302076 scopus 로고    scopus 로고
    • Angew. Chem. Int. Ed. 2007, 46, 5152-5155;
    • (2007) Angew. Chem. Int. Ed. , vol.46 , pp. 5152-5155
  • 65
    • 84954375997 scopus 로고    scopus 로고
    • European Medicines Agency, Guideline on the Specification Limits for Residues of Metal Catalysts
    • European Medicines Agency, Guideline on the Specification Limits for Residues of Metal Catalysts, 2008, http://www.ema.europa.eu/docs/en GB/document library/Scientific guideline/2009/09/WC500003587.pdf.
    • (2008)
  • 82
    • 33746305931 scopus 로고    scopus 로고
    • Angew. Chem. Int. Ed. 2006, 45, 1120-1123.
    • (2006) Angew. Chem. Int. Ed. , vol.45 , pp. 1120-1123
  • 85
    • 0043032746 scopus 로고    scopus 로고
    • Angew. Chem. Int. Ed. 2003, 42, 3501-3504.
    • (2003) Angew. Chem. Int. Ed. , vol.42 , pp. 3501-3504
  • 169


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.