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Volumn 16, Issue 12, 2015, Pages 1664-1672

JAK/STAT signaling in Drosophila muscles controls the cellular immune response against parasitoid infection

Author keywords

Drosophila; innate immunity; JAK STAT signaling; muscles

Indexed keywords

JANUS KINASE; STAT PROTEIN; CYTOKINE; DROSOPHILA PROTEIN; JANUS KINASE 1; PROTEIN TYROSINE KINASE; TRANSCRIPTION FACTOR; UPD2 PROTEIN, DROSOPHILA; UPD3 PROTEIN, DROSOPHILA;

EID: 84954373011     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.15252/embr.201540277     Document Type: Article
Times cited : (94)

References (57)
  • 1
    • 0015524896 scopus 로고
    • Inducible antibacterial defence system in Drosophila
    • Boman HG, Nilsson I, Rasmuson B, (1972) Inducible antibacterial defence system in Drosophila. Nature 237: 232-235
    • (1972) Nature , vol.237 , pp. 232-235
    • Boman, H.G.1    Nilsson, I.2    Rasmuson, B.3
  • 2
    • 0037290892 scopus 로고    scopus 로고
    • Drosophila immunity: Paths and patterns
    • Hultmark D, (2003) Drosophila immunity: paths and patterns. Curr Opin Immunol 15: 12-19
    • (2003) Curr Opin Immunol , vol.15 , pp. 12-19
    • Hultmark, D.1
  • 3
    • 34047268684 scopus 로고    scopus 로고
    • The host defense of Drosophila melanogaster
    • Lemaitre B, Hoffmann J, (2007) The host defense of Drosophila melanogaster. Annu Rev Immunol 25: 697-743
    • (2007) Annu Rev Immunol , vol.25 , pp. 697-743
    • Lemaitre, B.1    Hoffmann, J.2
  • 4
    • 34247103287 scopus 로고    scopus 로고
    • Drosophila hemopoiesis and cellular immunity
    • Williams MJ, (2007) Drosophila hemopoiesis and cellular immunity. J Immunol 178: 4711-4716
    • (2007) J Immunol , vol.178 , pp. 4711-4716
    • Williams, M.J.1
  • 5
    • 79955533160 scopus 로고    scopus 로고
    • Drosophila cellular immunity: A story of migration and adhesion
    • Fauvarque MO, Williams MJ, (2011) Drosophila cellular immunity: a story of migration and adhesion. J Cell Sci 124: 1373-1382
    • (2011) J Cell Sci , vol.124 , pp. 1373-1382
    • Fauvarque, M.O.1    Williams, M.J.2
  • 6
    • 0028922245 scopus 로고
    • Signals from the IL-1 receptor homolog, Toll, can activate an immune response in a Drosophila hemocyte cell line
    • Rosetto M, Engström Y, Baldari CT, Telford JL, Hultmark D, (1995) Signals from the IL-1 receptor homolog, Toll, can activate an immune response in a Drosophila hemocyte cell line. Biochem Biophys Res Commun 209: 111-116
    • (1995) Biochem Biophys Res Commun , vol.209 , pp. 111-116
    • Rosetto, M.1    Engström, Y.2    Baldari, C.T.3    Telford, J.L.4    Hultmark, D.5
  • 8
    • 0030595339 scopus 로고    scopus 로고
    • The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults
    • Lemaitre B, Nicolas E, Michaut L, Reichhart J-M, Hoffmann JA, (1996) The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 86: 973-983
    • (1996) Cell , vol.86 , pp. 973-983
    • Lemaitre, B.1    Nicolas, E.2    Michaut, L.3    Reichhart, J.-M.4    Hoffmann, J.A.5
  • 9
    • 84863281623 scopus 로고    scopus 로고
    • Genetic evidence of a redox-dependent systemic wound response via Hayan protease-phenoloxidase system in Drosophila
    • Nam HJ, Jang IH, You H, Lee KA, Lee WJ, (2012) Genetic evidence of a redox-dependent systemic wound response via Hayan protease-phenoloxidase system in Drosophila. EMBO J 31: 1253-1265
    • (2012) EMBO J , vol.31 , pp. 1253-1265
    • Nam, H.J.1    Jang, I.H.2    You, H.3    Lee, K.A.4    Lee, W.J.5
  • 11
    • 63449131302 scopus 로고    scopus 로고
    • Involvement of pro-phenoloxidase 3 in lamellocyte-mediated spontaneous melanization in Drosophila
    • Nam HJ, Jang IH, Asano T, Lee WJ, (2008) Involvement of pro-phenoloxidase 3 in lamellocyte-mediated spontaneous melanization in Drosophila. Mol Cells 26: 606-610
    • (2008) Mol Cells , vol.26 , pp. 606-610
    • Nam, H.J.1    Jang, I.H.2    Asano, T.3    Lee, W.J.4
  • 12
    • 33748912954 scopus 로고    scopus 로고
    • Melanotic mutants in Drosophila: Pathways and phenotypes
    • Minakhina S, Steward R, (2006) Melanotic mutants in Drosophila: pathways and phenotypes. Genetics 174: 253-263
    • (2006) Genetics , vol.174 , pp. 253-263
    • Minakhina, S.1    Steward, R.2
  • 13
    • 0019891136 scopus 로고
    • A genetic melanotic neoplasm of Drosophila melanogaster
    • Hanratty WP, Ryerse JS, (1981) A genetic melanotic neoplasm of Drosophila melanogaster. Dev Biol 83: 238-249
    • (1981) Dev Biol , vol.83 , pp. 238-249
    • Hanratty, W.P.1    Ryerse, J.S.2
  • 14
    • 0028938172 scopus 로고
    • Tum-l Jak kinase causes leukemia-like hematopoietic defects
    • Tum-l Jak kinase causes leukemia-like hematopoietic defects. EMBO J 14: 1412-1420
    • (1995) EMBO J , vol.14 , pp. 1412-1420
    • Luo, H.1    Hanratty, W.P.2    Dearolf, C.R.3
  • 15
    • 0029031668 scopus 로고
    • Activation of a Drosophila Janus kinase (JAK) causes hematopoietic neoplasia and developmental defects
    • Harrison DA, Binari R, Nahreini TS, Gilman M, Perrimon N, (1995) Activation of a Drosophila Janus kinase (JAK) causes hematopoietic neoplasia and developmental defects. EMBO J 14: 2857-2865
    • (1995) EMBO J , vol.14 , pp. 2857-2865
    • Harrison, D.A.1    Binari, R.2    Nahreini, T.S.3    Gilman, M.4    Perrimon, N.5
  • 16
    • 0024003902 scopus 로고
    • Zygotic expression and activity of the Drosophila Toll gene, a gene required maternally for embryonic dorsal-ventral pattern formation
    • Gerttula S, Jin Y, Anderson KV, (1988) Zygotic expression and activity of the Drosophila Toll gene, a gene required maternally for embryonic dorsal-ventral pattern formation. Genetics 119: 123-133
    • (1988) Genetics , vol.119 , pp. 123-133
    • Gerttula, S.1    Jin, Y.2    Anderson, K.V.3
  • 18
    • 1942485935 scopus 로고    scopus 로고
    • Genetic analysis of contributions of dorsal group and JAK-Stat92E pathway genes to larval hemocyte concentration and the egg encapsulation response in Drosophila
    • Sorrentino RP, Melk JP, Govind S, (2004) Genetic analysis of contributions of dorsal group and JAK-Stat92E pathway genes to larval hemocyte concentration and the egg encapsulation response in Drosophila. Genetics 166: 1343-1356
    • (2004) Genetics , vol.166 , pp. 1343-1356
    • Sorrentino, R.P.1    Melk, J.P.2    Govind, S.3
  • 19
    • 23844435317 scopus 로고    scopus 로고
    • Drosophila melanogaster Rac2 is necessary for a proper cellular immune response
    • Williams MJ, Ando I, Hultmark D, (2005) Drosophila melanogaster Rac2 is necessary for a proper cellular immune response. Genes Cells 10: 813-823
    • (2005) Genes Cells , vol.10 , pp. 813-823
    • Williams, M.J.1    Ando, I.2    Hultmark, D.3
  • 20
    • 33745205862 scopus 로고    scopus 로고
    • Rac1 signalling in the Drosophila larval cellular immune response
    • Williams MJ, Wiklund ML, Wikman S, Hultmark D, (2006) Rac1 signalling in the Drosophila larval cellular immune response. J Cell Sci 119: 2015-2024
    • (2006) J Cell Sci , vol.119 , pp. 2015-2024
    • Williams, M.J.1    Wiklund, M.L.2    Wikman, S.3    Hultmark, D.4
  • 21
    • 33847385449 scopus 로고    scopus 로고
    • Reciprocal regulation of Rac1 and Rho1 in Drosophila circulating immune surveillance cells
    • Williams MJ, Habayeb MS, Hultmark D, (2007) Reciprocal regulation of Rac1 and Rho1 in Drosophila circulating immune surveillance cells. J Cell Sci 120: 502-511
    • (2007) J Cell Sci , vol.120 , pp. 502-511
    • Williams, M.J.1    Habayeb, M.S.2    Hultmark, D.3
  • 22
    • 0035975940 scopus 로고    scopus 로고
    • Identification of the first invertebrate interleukin JAK/STAT receptor, the Drosophila gene domeless
    • Brown S, Hu N, Hombria JC, (2001) Identification of the first invertebrate interleukin JAK/STAT receptor, the Drosophila gene domeless. Curr Biol 11: 1700-1705
    • (2001) Curr Biol , vol.11 , pp. 1700-1705
    • Brown, S.1    Hu, N.2    Hombria, J.C.3
  • 23
    • 0027957316 scopus 로고
    • Stripe-specific regulation of pair-rule genes by hopscotch, a putative Jak family tyrosine kinase in Drosophila
    • Binari R, Perrimon N, (1994) Stripe-specific regulation of pair-rule genes by hopscotch, a putative Jak family tyrosine kinase in Drosophila. Genes Dev 8: 300-312
    • (1994) Genes Dev , vol.8 , pp. 300-312
    • Binari, R.1    Perrimon, N.2
  • 24
    • 0030040691 scopus 로고    scopus 로고
    • Marelle acts downstream of the Drosophila HOP/JAK kinase and encodes a protein similar to the mammalian STATs
    • Hou XS, Melnick MB, Perrimon N, (1996) marelle acts downstream of the Drosophila HOP/JAK kinase and encodes a protein similar to the mammalian STATs. Cell 84: 411-419
    • (1996) Cell , vol.84 , pp. 411-419
    • Hou, X.S.1    Melnick, M.B.2    Perrimon, N.3
  • 25
    • 0001514956 scopus 로고    scopus 로고
    • Identification of a Stat gene that functions in Drosophila development
    • Yan R, Small S, Desplan C, Dearolf CR, Darnell JE Jr, (1996) Identification of a Stat gene that functions in Drosophila development. Cell 84: 421-430
    • (1996) Cell , vol.84 , pp. 421-430
    • Yan, R.1    Small, S.2    Desplan, C.3    Dearolf, C.R.4    Darnell, J.E.5
  • 26
    • 0042932806 scopus 로고    scopus 로고
    • Molecular phylogeny within type i cytokines and their cognate receptors
    • Boulay JL, O'Shea JJ, Paul WE, (2003) Molecular phylogeny within type I cytokines and their cognate receptors. Immunity 19: 159-163
    • (2003) Immunity , vol.19 , pp. 159-163
    • Boulay, J.L.1    O'Shea, J.J.2    Paul, W.E.3
  • 27
    • 79951855477 scopus 로고    scopus 로고
    • Differential activities of the Drosophila JAK/STAT pathway ligands Upd, Upd2 and Upd3
    • Wright VM, Vogt KL, Smythe E, Zeidler MP, (2011) Differential activities of the Drosophila JAK/STAT pathway ligands Upd, Upd2 and Upd3. Cell Signal 23: 920-927
    • (2011) Cell Signal , vol.23 , pp. 920-927
    • Wright, V.M.1    Vogt, K.L.2    Smythe, E.3    Zeidler, M.P.4
  • 29
    • 84901826520 scopus 로고    scopus 로고
    • The Drosophila JAK-STAT pathway in blood cell formation and immunity
    • Morin-Poulard I, Vincent A, Crozatier M, (2013) The Drosophila JAK-STAT pathway in blood cell formation and immunity. JAKSTAT 2: e25700
    • (2013) JAKSTAT , vol.2 , pp. e25700
    • Morin-Poulard, I.1    Vincent, A.2    Crozatier, M.3
  • 31
    • 0344925804 scopus 로고    scopus 로고
    • Drosophila hemolectin gene is expressed in embryonic and larval hemocytes and its knock down causes bleeding defects
    • Goto A, Kadowaki T, Kitagawa Y, (2003) Drosophila hemolectin gene is expressed in embryonic and larval hemocytes and its knock down causes bleeding defects. Dev Biol 264: 582-591
    • (2003) Dev Biol , vol.264 , pp. 582-591
    • Goto, A.1    Kadowaki, T.2    Kitagawa, Y.3
  • 33
    • 37249024216 scopus 로고    scopus 로고
    • Expression and functional analysis of a novel Fusion Competent Myoblast specific GAL4 driver
    • Beckett K, Rochlin KM, Duan H, Nguyen HT, Baylies MK, (2008) Expression and functional analysis of a novel Fusion Competent Myoblast specific GAL4 driver. Gene Expr Patterns 8: 87-91
    • (2008) Gene Expr Patterns , vol.8 , pp. 87-91
    • Beckett, K.1    Rochlin, K.M.2    Duan, H.3    Nguyen, H.T.4    Baylies, M.K.5
  • 34
    • 84867961621 scopus 로고    scopus 로고
    • Of blood cells and the nervous system: Hematopoiesis in the Drosophila larva
    • Makhijani K, Bruckner K, (2012) Of blood cells and the nervous system: hematopoiesis in the Drosophila larva. Fly (Austin) 6: 254-260
    • (2012) Fly (Austin) , vol.6 , pp. 254-260
    • Makhijani, K.1    Bruckner, K.2
  • 36
    • 33947246071 scopus 로고    scopus 로고
    • Control of blood cell homeostasis in Drosophila larvae by the posterior signalling centre
    • Krzemien J, Dubois L, Makki R, Meister M, Vincent A, Crozatier M, (2007) Control of blood cell homeostasis in Drosophila larvae by the posterior signalling centre. Nature 446: 325-328
    • (2007) Nature , vol.446 , pp. 325-328
    • Krzemien, J.1    Dubois, L.2    Makki, R.3    Meister, M.4    Vincent, A.5    Crozatier, M.6
  • 37
    • 71949096183 scopus 로고    scopus 로고
    • Upregulation of the Drosophila Friend of GATA gene u-shaped by JAK/STAT signaling maintains lymph gland prohemocyte potency
    • Gao H, Wu X, Fossett N, (2009) Upregulation of the Drosophila Friend of GATA gene u-shaped by JAK/STAT signaling maintains lymph gland prohemocyte potency. Mol Cell Biol 29: 6086-6096
    • (2009) Mol Cell Biol , vol.29 , pp. 6086-6096
    • Gao, H.1    Wu, X.2    Fossett, N.3
  • 38
    • 79953029297 scopus 로고    scopus 로고
    • JAK/STAT and the GATA factor Pannier control hemocyte maturation and differentiation in Drosophila
    • Minakhina S, Tan W, Steward R, (2011) JAK/STAT and the GATA factor Pannier control hemocyte maturation and differentiation in Drosophila. Dev Biol 352: 308-316
    • (2011) Dev Biol , vol.352 , pp. 308-316
    • Minakhina, S.1    Tan, W.2    Steward, R.3
  • 39
    • 84455178975 scopus 로고    scopus 로고
    • Interaction between differentiating cell- and niche-derived signals in hematopoietic progenitor maintenance
    • Mondal BC, Mukherjee T, Mandal L, Evans CJ, Sinenko SA, Martinez-Agosto JA, Banerjee U, (2011) Interaction between differentiating cell- and niche-derived signals in hematopoietic progenitor maintenance. Cell 147: 1589-1600
    • (2011) Cell , vol.147 , pp. 1589-1600
    • Mondal, B.C.1    Mukherjee, T.2    Mandal, L.3    Evans, C.J.4    Sinenko, S.A.5    Martinez-Agosto, J.A.6    Banerjee, U.7
  • 40
    • 0032532120 scopus 로고    scopus 로고
    • Drosophila unpaired encodes a secreted protein that activates the JAK signaling pathway
    • Harrison DA, McCoon PE, Binari R, Gilman M, Perrimon N, (1998) Drosophila unpaired encodes a secreted protein that activates the JAK signaling pathway. Genes Dev 12: 3252-3263
    • (1998) Genes Dev , vol.12 , pp. 3252-3263
    • Harrison, D.A.1    McCoon, P.E.2    Binari, R.3    Gilman, M.4    Perrimon, N.5
  • 42
    • 67549133157 scopus 로고    scopus 로고
    • Cytokine/Jak/Stat signaling mediates regeneration and homeostasis in the Drosophila midgut
    • Jiang H, Patel PH, Kohlmaier A, Grenley MO, McEwen DG, Edgar BA, (2009) Cytokine/Jak/Stat signaling mediates regeneration and homeostasis in the Drosophila midgut. Cell 137: 1343-1355
    • (2009) Cell , vol.137 , pp. 1343-1355
    • Jiang, H.1    Patel, P.H.2    Kohlmaier, A.3    Grenley, M.O.4    McEwen, D.G.5    Edgar, B.A.6
  • 43
    • 78650397479 scopus 로고    scopus 로고
    • Drosophila EGFR pathway coordinates stem cell proliferation and gut remodeling following infection
    • Buchon N, Broderick NA, Kuraishi T, Lemaitre B, (2010) Drosophila EGFR pathway coordinates stem cell proliferation and gut remodeling following infection. BMC Biol 8: 152
    • (2010) BMC Biol , vol.8 , pp. 152
    • Buchon, N.1    Broderick, N.A.2    Kuraishi, T.3    Lemaitre, B.4
  • 45
    • 33644915010 scopus 로고    scopus 로고
    • Regular tai chi chuan exercise enhances functional mobility and CD4CD25 regulatory T cells
    • Yeh SH, Chuang H, Lin LW, Hsiao CY, Eng HL, (2006) Regular tai chi chuan exercise enhances functional mobility and CD4CD25 regulatory T cells. Br J Sports Med 40: 239-243
    • (2006) Br J Sports Med , vol.40 , pp. 239-243
    • Yeh, S.H.1    Chuang, H.2    Lin, L.W.3    Hsiao, C.Y.4    Eng, H.L.5
  • 46
    • 0033814923 scopus 로고    scopus 로고
    • Infections and exercise in high-performance athletes
    • Friman G, Wesslén L, (2000) Infections and exercise in high-performance athletes. Immunol Cell Biol 78: 510-522
    • (2000) Immunol Cell Biol , vol.78 , pp. 510-522
    • Friman, G.1    Wesslén, L.2
  • 47
    • 0035161806 scopus 로고    scopus 로고
    • Haemocyte changes in resistant and susceptible strains of D. Melanogaster caused by virulent and avirulent strains of the parasitic wasp Leptopilina boulardi
    • Russo J, Brehelin M, Carton Y, (2001) Haemocyte changes in resistant and susceptible strains of D. melanogaster caused by virulent and avirulent strains of the parasitic wasp Leptopilina boulardi. J Insect Physiol 47: 167-172
    • (2001) J Insect Physiol , vol.47 , pp. 167-172
    • Russo, J.1    Brehelin, M.2    Carton, Y.3
  • 48
    • 0037106184 scopus 로고    scopus 로고
    • Negative regulation of STAT92E by an N-terminally truncated STAT protein derived from an alternative promoter site
    • Henriksen MA, Betz A, Fuccillo MV, Darnell JE Jr, (2002) Negative regulation of STAT92E by an N-terminally truncated STAT protein derived from an alternative promoter site. Genes Dev 16: 2379-2389
    • (2002) Genes Dev , vol.16 , pp. 2379-2389
    • Henriksen, M.A.1    Betz, A.2    Fuccillo, M.V.3    Darnell, J.E.4
  • 50
    • 0032980725 scopus 로고    scopus 로고
    • P38 mitogen-activated protein kinase can be involved in transforming growth factor β superfamily signal transduction in Drosophila wing morphogenesis
    • Adachi-Yamada T, Nakamura M, Irie K, Tomoyasu Y, Sano Y, Mori E, Goto S, Ueno N, Nishida Y, Matsumoto K, (1999) p38 mitogen-activated protein kinase can be involved in transforming growth factor β superfamily signal transduction in Drosophila wing morphogenesis. Mol Cell Biol 19: 2322-2329
    • (1999) Mol Cell Biol , vol.19 , pp. 2322-2329
    • Adachi-Yamada, T.1    Nakamura, M.2    Irie, K.3    Tomoyasu, Y.4    Sano, Y.5    Mori, E.6    Goto, S.7    Ueno, N.8    Nishida, Y.9    Matsumoto, K.10
  • 51
    • 0033828645 scopus 로고    scopus 로고
    • Jun mediates Frizzled-induced R3/R4 cell fate distinction and planar polarity determination in the Drosophila eye
    • Weber U, Paricio N, Mlodzik M, (2000) Jun mediates Frizzled-induced R3/R4 cell fate distinction and planar polarity determination in the Drosophila eye. Development 127: 3619-3629
    • (2000) Development , vol.127 , pp. 3619-3629
    • Weber, U.1    Paricio, N.2    Mlodzik, M.3
  • 52
    • 0042697323 scopus 로고    scopus 로고
    • Signaling role of hemocytes in Drosophila JAK/STAT-dependent response to septic injury
    • Agaisse H, Petersen U-M, Boutros M, Mathey-Prevot B, Perrimon N, (2003) Signaling role of hemocytes in Drosophila JAK/STAT-dependent response to septic injury. Dev Cell 5: 441-450
    • (2003) Dev Cell , vol.5 , pp. 441-450
    • Agaisse, H.1    Petersen, U.-M.2    Boutros, M.3    Mathey-Prevot, B.4    Perrimon, N.5
  • 53
    • 73249135853 scopus 로고    scopus 로고
    • New hemocyte-specific enhancer-reporter transgenes for the analysis of hematopoiesis in Drosophila
    • Tokusumi T, Shoue DA, Tokusumi Y, Stoller JR, Schulz RA, (2009) New hemocyte-specific enhancer-reporter transgenes for the analysis of hematopoiesis in Drosophila. Genesis 47: 771-774
    • (2009) Genesis , vol.47 , pp. 771-774
    • Tokusumi, T.1    Shoue, D.A.2    Tokusumi, Y.3    Stoller, J.R.4    Schulz, R.A.5
  • 54
    • 10944238599 scopus 로고    scopus 로고
    • Increased expression of Drosophila tetraspanin, Tsp68C, suppresses the abnormal proliferation of ytr-deficient and Ras/Raf-activated hemocytes
    • Sinenko SA, Mathey-Prevot B, (2004) Increased expression of Drosophila tetraspanin, Tsp68C, suppresses the abnormal proliferation of ytr-deficient and Ras/Raf-activated hemocytes. Oncogene 23: 9120-9128
    • (2004) Oncogene , vol.23 , pp. 9120-9128
    • Sinenko, S.A.1    Mathey-Prevot, B.2
  • 55
    • 0029992508 scopus 로고    scopus 로고
    • Wingless signaling induces nautilus expression in the ventral mesoderm of the Drosophila embryo
    • Ranganayakulu G, Schulz RA, Olson EN, (1996) Wingless signaling induces nautilus expression in the ventral mesoderm of the Drosophila embryo. Dev Biol 176: 143-148
    • (1996) Dev Biol , vol.176 , pp. 143-148
    • Ranganayakulu, G.1    Schulz, R.A.2    Olson, E.N.3
  • 56
    • 0030020645 scopus 로고    scopus 로고
    • Autonomous and nonautonomous Notch functions for embryonic muscle and epidermis development in Drosophila
    • Baker R, Schubiger G, (1996) Autonomous and nonautonomous Notch functions for embryonic muscle and epidermis development in Drosophila. Development 122: 617-626
    • (1996) Development , vol.122 , pp. 617-626
    • Baker, R.1    Schubiger, G.2
  • 57
    • 25444494901 scopus 로고    scopus 로고
    • Quantification strategies in real-time PCR
    • Bustin S.A. (ed), La Jolla, CA, USA: International University Line (IUL)
    • Pfaffl MW, (2004) Quantification strategies in real-time PCR. In A-Z of Quantitative PCR, Bustin SA, (ed), pp 87-112. La Jolla, CA, USA: International University Line (IUL)
    • (2004) A-Z of Quantitative PCR , pp. 87-112
    • Pfaffl, M.W.1


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